Oncology and biomedicine terminology · MLC-0111
Oncology and biomedicine terms: S (1,286)
- S-1A drug that is being studied for its ability to enhance the effectiveness of fluorouracil and prevent...
- S100 calcium binding protein A8A protein that is made by many different types of cells and is involved in processes that take place both...
- S100 calcium binding protein A9A protein that is made by many different types of cells and is involved in processes that take place both...
- S-3304An orally-agent agent with potential antineoplastic activity. S-3304 inhibits matrix metalloproteinases...
- SABA temporary loss of feeling in the abdomen and/or the lower part of the body. Special drugs called...
- sabarubicinA disaccharide analogue of the anthracycline antineoplastic antibiotic doxorubicin. Sabarubicin intercalates...
- sabatolimabAn inhibitor of the inhibitory T-cell receptor T-cell immunoglobulin and mucin domain-containing protein 3...
- sabizabulinAn orally bioavailable, small molecule tubulin inhibitor, with potential antineoplastic, antiviral and...
- SABRA type of external radiation therapy that uses special equipment to position a patient and precisely deliver...
- Saccharomyces boulardii probiotic supplementA probiotic containing the non-pathogenic yeast Saccharomyces boulardii with antidiarrheal and potential...
- sacituzumab govitecanA drug used to treat adults with certain types of breast cancer that have already been treated with other...
- sacituzumab govitecan-hziyAn antibody drug conjugate containing the humanized monoclonal antibody, hRS7, against tumor-associated...
- sacituzumab tirumotecanAn antibody-drug conjugate (ADC) composed of a monoclonal antibody against tumor-associated antigen (TAA)...
- sacrumThe large, triangle-shaped bone in the lower spine that forms part of the pelvis. It is made of 5 fused bones...
- sacubitrilA neprilysn (NEP) inhibitor prodrug with natriuretic activity. Upon administration, sacubitril is metabolized...
- S-adenosyl-L-methionine disulfate p-toluene-sulfonateThe disulfate salt of the stable p-toluene-sulfonate complex of s-adenosyl-L-methionine (SAMe) with...
- S-adenosylmethionineA nutritional supplement that is synthesized from adenosine triphosphate (ATP) and the amino acid methionine...
- safingolA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
- safusidenibAn orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1; IDH-1; IDH1 [NADP+] soluble) mutant...
- sagopiloneA fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to...
- SAHAA drug used to treat cutaneous T-cell lymphoma that came back, got worse, or did not get better during or...
- salineA solution of salt and water.
- salirasibA salicylic acid derivative with potential antineoplastic activity. Salirasib dislodges all Ras isoforms from...
- salivaThe clear, watery fluid in the mouth made by the salivary glands. Saliva moistens food to help with chewing...
- salivary glandA gland in the mouth that produces saliva.
- salivary gland cancerA rare cancer that forms in tissues of a salivary gland (gland in the mouth that makes saliva). Most salivary...
- Salmonella enterica serotype typhimurium expressing L-methioninase SGN1A genetically modified strain of Salmonella enterica, serotype typhimurium that expresses L-methioninase...
- Salmonella enterica serovar typhi ZH9A formulation containing a live-attenuated strain of the bacterium Salmonella typhi, with potential...
- salmonella VNP20009A genetically stable Salmonella typhimurium strain, attenuated by chromosomal deletion of the purI and msbB...
- salpingo-oophorectomySurgical removal of the fallopian tubes and ovaries.
- salsalateAn orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory...
- salt-inducible kinase inhibitor GRN-300An orally bioavailable small molecule inhibitor of the salt inducible kinases 2 (SIK2) and 3 (SIK3), with...
- salvage therapyTreatment that is given after the cancer has not responded to other treatments.
- Salvia hispanica seedThe edible seed of the flowering plant Salvia hispanica (chia) used as a nutritional supplement, with...
- Salvia officinalis extract tabletAn oral tablet containing an extract of the plant Salvia officinalis (common sage) with reported...
- Sam68 modulator CWP232291A small molecule and prodrug of CWP232204 targeting Src associated in mitosis, of 68 kDa (Sam68 or KHDRBS1)...
- samalizumabA humanized monoclonal antibody directed against the human immunosuppressive molecule CD200 (OX-2) with...
- samarium Sm 153A radioactive substance used to treat bone cancer and other cancers that have spread to the bone. Samarium Sm...
- samarium Sm 153-DOTMPA radioconjugate composed of the phosphonic acid chelator DOTMP...
- samarium Sm 153-lexidronam pentasodiumA drug used to treat bone pain caused by bone cancer and other cancers that have spread to the bone. It...
- sample sizeThe number of participants involved in the different treatment groups. A larger sample size provides stronger...
- samrotamab vedotinAn antibody-drug conjugate (ADC) composed of a humanized monoclonal antibody against leucine-rich repeat...
- samuraciclibAn orally available, selective inhibitor of cyclin-dependent kinase 7 (CDK7) with potential antineoplastic...
- San Zhong Kui Jian TangA traditional Chinese herbal medicine containing sixteen or seventeen herbs, including berberine and...
- SancusoA drug used alone or with other drugs in adults to prevent nausea and vomiting caused by chemotherapy...
- Sanger sequencingA low-throughput laboratory method used to determine the nucleotide sequence of a piece of DNA. Sanger...
- sapablursenAn antisense oligonucleotide (ASO) targeting the transmembrane protease serine 6 (TMPRSS6) mRNA and...
- sapacitabineAn orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity. Sapacitabine is...
- sapanisertibAn orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or...
- sapitinibAn erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. Sapitinib binds to and...
- saponinA substance found in soybeans and many other plants. Saponins may help lower cholesterol and may have...
- saponin-based immunoadjuvant OBI-821A purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential...
- saponin-cholesterol-phospholipid adjuvantAn adjuvant comprised of saponin, derived from the bark of Quillaia saponaria Molina, cholesterol and...
- saquinavir mesylateA drug that belongs to the family of drugs called protease inhibitors. It interferes with the ability of a...
- saracatinibAn orally available 5-, 7-substituted anilinoquinazoline with anti-invasive and anti-tumor activities...
- SarclisaA drug used with other drugs to treat adults with certain types of multiple myeloma. It is also being studied...
- sarCNUA substance being studied in the treatment of cancer. It is a type of alkylating agent. Also called...
- sarcoidAn inflammatory disease marked by the formation of granulomas (small nodules of immune cells) in the lungs...
- sarcoidosisAn inflammatory disease marked by the formation of granulomas (small nodules of immune cells) in the lungs...
- sarcomaA type of cancer that begins in bone or in the soft tissues of the body, including cartilage, fat, muscle...
- sarcomatoid carcinomaA type of cancer that looks like a mixture of carcinoma (cancer that begins in the skin or in tissues that...
- sarcopeniaA condition characterized by loss of muscle mass, strength, and function in older adults. Signs and symptoms...
- sarcosinamide nitrosoureaA substance being studied in the treatment of cancer. It is a type of alkylating agent. Also called sarCNU.
- sargramostimA substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that...
- sargramostim plasmid DNA hepatocellular carcinoma vaccine adjuvantA vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (granulocyte-macrophage...
- sargramostim plasmid DNA melanoma vaccine adjuvantA vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (a granulocyte macrophage-colony...
- sargramostim plasmid DNA pancreatic tumor cell vaccineA whole cell vaccine comprised of irradiated allogenic pancreatic tumor cells transfected with a plasmid DNA...
- sarilumabA recombinant, human immunoglobulin (IgG) monoclonal antibody targeting the interleukin 6 receptor (IL-6R)...
- SARS-CoV-2The virus that causes a respiratory disease called coronavirus disease 19 (COVID-19). SARS-CoV-2 is a member...
- SARS-CoV-2 spike protein plasmid DNA vaccine CORVaxA vaccine consisting of DNA plasmids encoding the severe acute respiratory syndrome-coronavirus 2...
- saruparibAn orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP), with potential...
- sasanlimabAn inhibitor of the human inhibitory receptor programmed cell death 1 (PD-1; PDCD1), with potential immune...
- satellite tumorA group of tumor cells in an area near the primary (original) tumor. In melanoma, satellite tumors occur...
- satraplatinA substance being studied in the treatment of prostate and other types of cancer. It contains the metal...
- saturated fatA type of fat with certain chemical properties that is usually solid at room temperature. Most saturated fats...
- savolitinibAn orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic...
- saw palmettoA shrub that is a member of the palm tree family. An extract made from the berries of this shrub has been...
- saw palmetto berry extract supplementAn herbal supplement used commonly to alleviate symptoms of benign prostatic hyperplasia. In vitro studies...
- saxagliptin hydrochlorideThe hydrochloride salt form of saxagliptin, an orally bioavailable, potent, selective and competitive...
- SB-715992A substance being studied in the treatment of cancer. SB-715992 blocks a protein that tumor cells need to...
- SB-743921A synthetic small molecule with potential antineoplastic properties. SB-743921 selectively inhibits kinesin...
- SB939A substance being studied in the treatment of several types of cancer. SB939 blocks the action of an enzyme...
- SB-AS02B adjuvantA proprietary oil-in-water emulsion specifically designed for combining protein preparations used in...
- SB-AS15 adjuvantA vaccine adjuvant containing CpG 7909, monophosphoryl lipid, and QS-21 with potential antineoplastic and...
- SBRTA type of external radiation therapy that uses special equipment to position a patient and precisely deliver...
- SC-70935A substance being studied for its ability to stimulate the production of blood cells during chemotherapy. It...
- scalpelA small, thin knife used for surgery.
- scanA type of test that makes detailed pictures of areas inside the body. A scan may also refer to the picture...
- scannerIn medicine, an instrument that takes pictures of the inside of the body.
- scapulaOne of a pair of triangular bones at the back of the shoulder. The scapula connects the collarbone with the...
- scar tissueFibrous tissue that forms when normal tissue is destroyed by disease, injury, or surgery. For example, scar...
- scatter radiationRadiation that spreads out in different directions from a radiation beam when the beam interacts with a...
- scattered fibroglandular breast tissueA term used to describe breast tissue that is made up of mostly fatty tissue and also has some dense fibrous...
- SCD1 inhibitor MTI-301An orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor, with potential antineoplastic and...
- ScemblixA drug used to treat adults with chronic phase chronic myelogenous leukemia that is Philadelphia chromosome...
- SCFA substance that causes blood stem cells (cells from which other types of cells develop) to change into...
- SCH 66336An anticancer drug that belongs to the family of drugs called enzyme inhibitors. Also called lonafarnib.
- SCH-58500A substance that has been studied in the treatment of some types of cancer. SCH-58500 is a weakened...
- Schedule I controlled substanceA drug or other substance that has a high chance of being abused or causing addiction and has no FDA-approved...
- Schedule I drugA drug or other substance that has a high chance of being abused or causing addiction and has no FDA-approved...
- Schiller testA test in which iodine is applied to the cervix. The iodine colors healthy cells brown; abnormal cells remain...
- schistosomeA parasitic worm that can cause diseases of the liver, bladder, and gastrointestinal tract. One type of...
- schizophreniaA group of severe mental disorders in which a person has trouble telling the difference between real and...
- school liaisonA person who helps a child return to school after a serious illness, such as cancer, or a long hospital stay...
- Schwann cellA type of glial cell of the peripheral nervous system that helps separate and insulate nerve cells.
- schwannomaA tumor of the peripheral nervous system that arises in the nerve sheath (protective covering). It is almost...
- SCIDA rare, inherited disease that is marked by a lack of B lymphocytes (white blood cells that make antibodies...
- scientific review committeeA group of doctors, scientists, and other experts that reviews the detailed plan of a clinical trial for...
- scientific review panelA group of doctors, scientists, and other experts that reviews the detailed plan of a clinical trial for...
- scientistA person who has studied science, especially one who is active in a particular field of investigation.
- scintigraphyA procedure that produces pictures (scans) of structures inside the body, including areas where there are...
- scintimammographyA type of breast imaging test that is used to detect cancer cells in the breasts of some women who have had...
- scleraThe white layer of the eye that covers most of the outside of the eyeball.
- sclerodermaA chronic disorder marked by hardening and thickening of the skin. Scleroderma can be localized or it can...
- sclerosing adenosisA benign (not cancerous) condition in which scar-like fibrous tissue is found in the breast lobules (the...
- sclerosing epithelioid fibrosarcomaA rare, type of cancer that forms in fibrous (connective) tissue. Sclerosing epithelioid fibrosarcoma is a...
- Sclerosol Intrapleural AerosolA mist or powdered form of the mineral magnesium silicate that is used to prevent malignant pleural effusions...
- sclerotherapyA treatment used to destroy abnormal blood vessels. A liquid is injected into a blood vessel, causing it to...
- scoliosisA condition marked by a side-to-side curve of the backbone. The curve is usually shaped like an S or a C. In...
- SC-PEG E. coli L-asparaginaseA drug used with other drugs to treat acute lymphoblastic leukemia in children and young adults aged 1 month...
- screeningChecking for disease when there are no symptoms. Since screening may find diseases at an early stage, there...
- screening mammogramAn x-ray image of the breast used to check for breast cancer in people who have no signs or symptoms of the...
- screening testA test that checks for a disease or condition before symptoms appear. Screening tests may help find diseases...
- scrotal edemaA buildup of fluid in the scrotum (sac around the testicles). This causes swelling on one or both sides of...
- scrotumIn males, the external sac that contains the testicles.
- Scutellaria barbataAn herb that belongs to a group of herbs named the Scutellaria species or scullcap. Both the root and the...
- SDF-1 receptor antagonist PTX-9908A stromal cell-derived factor 1 (SDF-1; CXCL12) analog and inhibitor of C-X-C chemokine receptor type 4...
- SDOHThe social, economic, and physical conditions in the places where people are born and where they live, learn...
- SDRA way of describing how family members are related to each other when there is one other family member in the...
- SDSA rare, inherited disorder in which the pancreas and bone marrow do not work the way they should. Symptoms...
- SDX-102A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
- sebaceomaA rare, benign (not cancer) tumor that forms in an oil gland in the skin. Most sebaceomas appear as yellow...
- sebaceous epitheliomaA rare, benign (not cancer) tumor that forms in an oil gland in the skin. Most sebaceous epitheliomas appear...
- sebumAn oily substance produced by certain glands in the skin.
- Sec61 inhibitor KZR-261A small molecule inhibitor of the Sec61 translocon, with potential antineoplastic activity. Upon...
- seclidemstatAn orally available, reversible, noncompetitive inhibitor of lysine-specific demethylase 1 (LSD1, or KDM1A)...
- second opinionIn medicine, the opinion of a doctor other than the patient’s current doctor. The second doctor reviews the...
- second primary cancerA term used to describe a new primary cancer that occurs in a person who has had cancer in the past. Second...
- secondary cancerA term used to describe cancer that has spread (metastasized) from the place where it first started to...
- secondary endpointIn clinical trials, an additional result beyond the primary endpoint measured at the end of the study.
- secondary ovarian failureA condition in which the ovaries stop working and menstrual periods stop before age 40. This can cause...
- secondary ovarian insufficiencyA condition in which the ovaries stop working and menstrual periods stop before age 40. This can cause...
- secondary tumorA term used to describe cancer that has spread (metastasized) from the place where it first started to...
- second-degree relativeA way of describing how family members are related to each other when there is one other family member in the...
- secondhand smokeSmoke that comes from the burning of a tobacco product and smoke that is exhaled by smokers. Inhaling...
- second-line therapyTreatment that is given when initial treatment (first-line therapy) doesn’t work, or stops working.
- second-look surgerySurgery performed after primary treatment to determine whether tumor cells remain.
- secreteTo form and release a substance. In the body, cells secrete substances, such as sweat that cools the body or...
- secretinA hormone released into the blood by cells in the inner layer of the small intestine. It is released when...
- secretin humanA drug used to help diagnose gastrinomas (tumors that cause too much gastric acid to be made) and other...
- secretin stimulation testA test used to measure the ability of the pancreas to respond to a hormone called secretin. Secretin causes...
- secukinumabA recombinant human immunoglobulin G1 (IgG1) monoclonal antibody against the pro-inflammatory cytokine...
- sedationA state of calmness, relaxation, or sleepiness caused by certain drugs. Sedation may be used to help relieve...
- sedativeA drug or substance used to calm a person down, relieve anxiety, or help a person sleep.
- sedimentation rateThe distance red blood cells travel in one hour in a sample of blood as they settle to the bottom of a test...
- sedoxantrone trihydrochlorideA substance being studied in the treatment of some types of cancer. Sedoxantrone trihydrochloride binds to...
- SEER ProgramA program of the National Cancer Institute that uses information collected by cancer registries to report on...
- SEGAA benign (not cancer), slow-growing tumor that usually forms in the walls of fluid-filled spaces in the...
- segmental cystectomySurgery to remove part of the bladder (the organ that holds urine). Also called partial cystectomy.
- segmental mastectomySurgery to remove cancer or other abnormal tissue from the breast and some normal tissue around it, but not...
- segmental resectionSurgery to remove part of an organ or gland. It may also be used to remove a tumor and normal tissue around...
- segmentectomySurgery to remove part of an organ or gland. It may also be used to remove a tumor and normal tissue around...
- segregation analysisThe process of fitting formal genetic models to data on expressed disease characteristics (phenotype) in...
- seizureSudden, uncontrolled body movements and changes in behavior that occur because of abnormal electrical...
- selatinib ditosilateAn orally bioavailable ditosilate salt form of selatinib, an analog of the quinazoline lapatinib and dual...
- selected vegetables/Sun's soupA mixture of vegetables and other edible plants that has been studied in the treatment of cancer. The...
- selection biasAn error in choosing the individuals or groups to take part in a study. Ideally, the subjects in a study...
- selective androgen receptor modulator LY2452473An orally bioavailable selective androgen receptor modulator (SARM), with potential tissue-selective...
- selective cytokine inhibitory drug CC-1088An analog of thalidomide with potential antineoplastic activity that belongs to the functional class of...
- selective estrogen receptor covalent antagonist H3B-6545An orally available, selective and covalent antagonist of estrogen receptor alpha (ERalpha; ERa; ESR1...
- selective estrogen receptor covalent antagonist TQB3915An orally bioavailable, selective and covalent antagonist of estrogen receptor alpha (ERalpha; ERa; ESR1...
- selective estrogen receptor degraderA drug that binds to and breaks down proteins called estrogen receptors (ERs), which are found inside the...
- selective estrogen receptor degrader AND019An orally bioavailable selective estrogen receptor degrader/downregulator (SERD), with potential...
- selective estrogen receptor degrader AZD9496An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon...
- selective estrogen receptor degrader LX-039A bispecific antibody fusion protein directed against the human negative immunoregulatory checkpoint...
- selective estrogen receptor degrader SRN-927An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic...
- selective estrogen receptor degraderLSZ102A selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon...
- selective estrogen receptor modulatorA drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen...
- selective human estrogen-receptor alpha partial agonist TTC-352A benzothiophene and orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial...
- selective serotonin reuptake inhibitorA type of drug that is used to treat depression and some other conditions. Selective serotonin reuptake...
- selegiline hydrochlorideThe hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with...
- seleniumA mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of...
- self-esteemA feeling of self-worth, self-confidence, and self-respect.
- seliciclibAn orally bioavailable, small-molecule cyclin-dependent kinase (CDK) inhibitor with potential proapoptotic...
- selicrelumabA monoclonal antibody agonist of the cell surface receptor CD40, with potential immunostimulatory and...
- selinexorA drug used alone or with other drugs to treat adults with certain types of diffuse large B-cell lymphoma or...
- sella turcicaA depression of the bone at the base of the skull where the pituitary gland is located.
- selpercatinibA drug used to treat certain types of non-small cell lung cancer in adults and certain types of thyroid...
- SelumetinibAn orally active, small molecule with potential antineoplastic activity. Selumetinib is an ATP-independent...
- selumetinib sulfateA drug used to treat children aged 2 years and older with a rare genetic condition called neurofibromatosis...
- semaglutideA glucagon-like peptide-1 (GLP-1) receptor agonist that is 94% homologous to human GLP-1 (7-37), with...
- semaxanibA substance that has been studied in the treatment of cancer. It belongs to the families of drugs called...
- semenThe fluid that is released through the penis during orgasm. Semen is made up of sperm from the testicles and...
- Se-methyl-seleno-L-cysteineA substance that contains the element selenium (a nutrient that protects cells against damage) and is found...
- seminal fluidFluid from the prostate and other sex glands that helps transport sperm out of the man's body during orgasm...
- seminal vesicleA gland that helps produce semen.
- seminal vesicle biopsyThe removal of fluid or tissue with a needle from the seminal vesicles for examination under a microscope...
- seminomaA type of cancer that begins in germ cells in males. Germ cells are cells that form sperm in males or eggs in...
- semiparasiticIn botany, a plant that gets food from a host but also contains chlorophyll and is capable of photosynthesis.
- semuloparinAn ultralow-molecular-weight heparin (ULMWH) (Mw: 2000-3000 daltons) consisting of a polydisperse mixture of...
- semustineA substance that has been studied in the treatment of some types of cancer. Semustine damages the cell’s DNA...
- senaparibAn orally bioavailable inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with...
- Seneca Valley virus-001A virus being studied in the treatment of neuroendocrine tumors and other types of cancer. Neuroendocrine...
- senega rootThe root of an herb called Polygala senega. It has been used in some cultures to treat certain medical...
- senescenceThe process of growing old. In biology, senescence is a process by which a cell ages and permanently stops...
- senile keratosisA thick, scaly patch of skin that may become cancer. It usually forms on areas exposed to the sun, such as...
- senna extractAn extract made from the dried leaflets on the pods of Cassia angustifolia or Cassia acutifolia with...
- senna fruitThe fruit of Cassia acutifolia and Cassia angustifolia (Cassia) with laxative and purgative activities. The...
- sensesIn medicine, the ways in which the body receives signals from the environment. The five human senses are...
- sensitivityIn medicine, sensitivity may describe how well a test can detect a specific disease or condition in people...
- sensorA device that responds to a stimulus, such as heat, light, or pressure, and generates a signal that can be...
- SensorcaineA drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain...
- sensoryHaving to do with the senses.
- sentinel lymph nodeThe first lymph node to which cancer is likely to spread from the primary tumor. When cancer spreads, the...
- sentinel lymph node biopsyRemoval and examination of the sentinel node(s) (the first lymph node(s) to which cancer cells are likely to...
- sentinel lymph node mappingThe use of dyes and radioactive substances to identify the first lymph node to which cancer is likely to...
- seocalcitolA substance that is being studied as a treatment for cancer. It belongs to the family of drugs called vitamin...
- sepantronium bromideA small-molecule proapoptotic agent with potential antineoplastic activity. Sepantronium bromide selectively...
- sepsisAn extreme immune response to infection that can lead to tissue damage, organ failure, or death if not...
- septateAn organ or structure that is divided into compartments.
- septicemiaDisease caused by the spread of bacteria and their toxins in the bloodstream. Also called blood poisoning and...
- sequential AC/Taxol-Trastuzumab regimenAn abbreviation for a chemotherapy combination used to treat breast cancer. It includes the drugs doxorubicin...
- sequential treatmentOne treatment after the other.
- S-equolAn orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid...
- serabelisibAn orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential...
- SERDA drug that binds to and breaks down proteins called estrogen receptors (ERs), which are found inside the...
- SERD SHR9549An orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic...
- SERD ZB716An orally bioavailable selective estrogen receptor degrader/downregulator (SERD) and a structural analog of...
- serdemetanAn orally bioavailable, small-molecule HDM2 antagonist with potential antineoplastic activity. Serdemetan...
- seribantumabA fully human monoclonal antibody directed against the human epidermal growth factor receptor ErbB3 (Her3)...
- serine hydrolase monoacylglycerol lipase inhibitor ABX-1431An orally bioavailable inhibitor of the serine hydrolase monoacylglycerol lipase (MGLL), with potential use...
- serine protease inhibitor WX-671An orally bioavailable, 3-amidinophenylalanine-derived, second generation serine protease inhibitor prodrug...
- serine/threonine kinase inhibitor CBP501A peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple...
- serine/threonine kinase inhibitor XL418A selective, orally active small molecule, targeting protein kinase B (PKB or AKT) and ribosomal protein S6...
- SERMA drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen...
- seroconversionThe production of antibodies (proteins) in the blood of a person who did not have the antibodies before. It...
- serologyThe examination of antibodies and other substances in the serum (clear liquid part of the blood). Serology...
- serology testA laboratory test that checks for the presence of antibodies or other substances in a blood sample...
- seromaA mass or lump caused by a buildup of clear fluid in a tissue, organ, or body cavity. It usually goes away on...
- SeromycinA drug used to treat tuberculosis. It is also being studied in the treatment of pain and nerve problems...
- seronegativeDescribes a laboratory test result that shows that a substance the test is supposed to find, such as an...
- seropositiveDescribes a laboratory test result that shows the presence of a specific marker, usually an antibody, in the...
- seroprevalenceThe percentage of people in a population who have proteins called antibodies in their blood that show they...
- serosaThe outer lining of organs and body cavities of the abdomen and chest, including the stomach. Also called...
- serotoninA substance that is found mostly in the digestive tract, central nervous system (brain and spinal cord), and...
- serotonin-norepinephrine reuptake inhibitorA type of drug that is used to treat depression and some other conditions. Serotonin-norepinephrine reuptake...
- serotypeDescribes a way of grouping cells or microorganisms, such as bacteria or viruses, based on the antigens or...
- serousHaving to do with serum, the clear liquid part of blood.
- serous membraneThe outer lining of organs and body cavities of the abdomen and chest, including the stomach. Also called...
- serplulimabA humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed...
- serrated polypA type of polyp (abnormal growth) that usually forms on the inner lining of the colon or rectum but can also...
- Sertoli cell tumorA rare tumor that usually forms in the testicles. It may also form in the ovaries, but this is very rare...
- Sertoli-Leydig cell tumorA rare tumor that forms in the tissues that surround and support the ovaries. Sertoli-Leydig cell tumors make...
- sertralineA drug used to treat depression. It is a type of selective serotonin reuptake inhibitor (SSRI). Also called...
- sertraline hydrochlorideThe hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and...
- serumThe clear liquid part of the blood that remains after blood cells and clotting proteins have been removed.
- serum albuminThe main protein in blood plasma. Low levels of serum albumin occur in people with malnutrition...
- serum glutamate pyruvate transaminaseAn enzyme found in the liver and other tissues. A high level of serum glutamate pyruvate transaminase...
- serum glutamic-oxaloacetic transaminaseAn enzyme found in the liver, heart, and other tissues. A high level of serum glutamic-oxaloacetic...
- serum tumor marker testA blood test that measures the amount of substances called tumor markers (or biomarkers). Tumor markers are...
- serum-derived bovine immunoglobulin protein isolateA nutritional supplement composed of serum-derived bovine protein concentrate containing high levels of...
- SerzoneA drug used to treat depression. It belongs to the family of drugs called antidepressant agents. Also called...
- SESA way of describing people based on their education, income, and type of job. SES is usually described as...
- sesquiterpene lactoneA substance found in some plants. Sesquiterpene lactones may have anti-inflammatory and anticancer effects...
- sestamibi breast imagingA type of breast imaging test that is used to detect cancer cells in the breasts of some women who have had...
- sestamibi scanAn imaging test used to find overactive parathyroid glands (four pea-sized glands found on the thyroid) and...
- setanaxibAn orally bioavailable inhibitor of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) 1...
- SETD2 inhibitor EZM0414An orally bioavailable selective inhibitor of the histone methyltransferase (HMT) SETD2 (SET domain...
- sevabertinibAn orally bioavailable, mutant-selective, dual kinase inhibitor of epidermal growth factor receptor (EGFR)...
- seventh cranial nerveA nerve that runs from the brainstem, through openings in the skull, to the face and tongue. The seventh...
- severe acute respiratory syndrome coronavirus 2The virus that causes a respiratory disease called coronavirus disease 19 (COVID-19). Severe acute...
- severe combined immunodeficiency diseaseA rare, inherited disease that is marked by a lack of B lymphocytes (white blood cells that make antibodies...
- severe myelosuppressionA severe form of myelosuppression. Myelosuppression is a condition in which bone marrow activity is...
- seviteronelAn orally available non-steroidal, lyase-selective inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase...
- sevofluraneA fluorinated isopropyl ether with general anesthetic activity. Although the mechanism of action has not been...
- sex cellAn egg cell in females or sperm cell in males. Each mature sex cell contains 23 chromosomes. When an egg...
- sex cord tumorA rare type of cancer that forms in the tissues that support the ovaries or testes. These tumors may release...
- sex cord-gonadal stromal tumorA rare type of cancer that forms in the tissues that support the ovaries or testes. These tumors may release...
- sex cord-stromal tumorA rare type of cancer that forms in the tissues that support the ovaries or testes. These tumors may release...
- sex driveThe need for sex. Also called sexual drive.
- sexual driveThe need for sex. Also called sex drive.
- sexualityA person's behaviors, desires, and attitudes related to sex and physical intimacy with others.
- sexually transmitted diseaseA disease caused by infection with certain bacteria, viruses, or other microorganisms that can be passed from...
- sexually transmitted infectionA disease caused by infection with certain bacteria, viruses, or other microorganisms that can be passed from...
- Sézary cellA cancerous T cell (a type of white blood cell) found in the blood, skin, and lymph nodes of patients who...
- Sézary syndromeA cancer that affects the skin. It is a form of cutaneous T-cell lymphoma.
- SGI-110A substance being studied in the treatment of some types of cancer. SGI-110 may stop the growth of tumor...
- SGN-00101A substance that is being studied in the prevention of cancer. It belongs to the family of drugs called...
- SGN-30A monoclonal antibody that binds to cells that have the CD30 antigen on their surface, including Hodgkin...
- SGN-35A drug used alone or with other drugs to treat adults with certain types of classic Hodgkin lymphoma...
- SGN-40A monoclonal antibody that binds to cells that have the CD40 antigen on their surface, including cells from...
- SGOTAn enzyme found in the liver, heart, and other tissues. A high level of SGOT released into the blood may be a...
- SGPTAn enzyme found in the liver and other tissues. A high level of SGPT released into the blood may be a sign of...
- sham-controlledAn inactive procedure that is designed to mimic as closely as possible the active procedure being studied in...
- shared decision makingIn medicine, a process in which both the patient and health care professional work together to decide the...
- shark cartilageA nutritional supplement gleaned from the exoskeleton of the shark. Shark cartilage inhibits...
- shark cartilage extract AE-941A multifunctional antiangiogenic agent derived from shark cartilage with potential antineoplastic activity...
- shave biopsyA procedure in which a skin abnormality and a thin layer of surrounding skin are removed with a small blade...
- sheddase inhibitor INCB007839An orally bioavailable inhibitor of the ADAM (A Disintegrin And Metalloprotease) family of multifunctional...
- sheep sorrelA plant that has been used in some cultures to treat certain medical problems. It may have anticancer...
- Sheng Di HuangA Chinese herbal medicine (CHM) derived from the root tuber of perennial herbaceous plant Rehmannia glutinosa...
- Sheng-Mai SanA Chinese herbal medicine composed of extracts from the roots of Panax ginseng (ren shen) and Ophiopogon...
- Sheng-Yu-TangA traditional Chinese medicine (TCM) containing Radix rehmanniae praeparata, Radix paeoniae alba, Radix...
- Shenqi Fuzheng injection SQ001An injectable formulation composed of the two Chinese medicinal herbs Radix astragali, the root of astragalus...
- Sheridan’s FormulaA liquid mixture that has been promoted as a treatment for cancer and other diseases. None of the ingredients...
- Shi Pi Yin herbal decoctionA traditional Chinese medicine (TCM) decoction containing a mixture of Aconiti lateral root, Zingiberis...
- shiitake mushroomA dark oriental mushroom widely used as a food. Several anticancer substances have been found in shiitake...
- shinboneThe larger of two bones between the knee and ankle. Also called tibia.
- shinglesA common condition that occurs when the virus that causes chickenpox is reactivated in the body. After having...
- short chain fatty acid HQK-1004A short chain fatty acid (SCFA) with potential herpes simplex virus thymidine kinase gene (HSV-TK)-inducing...
- short hairpin RNA-IL-6 gene silencing anti-CD19 CAR T cellsA preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor...
- short-term side effectA problem that is caused by treatment of a disease but usually goes away after treatment ends. Short-term...
- Sho-saiko-toA Japanese formulation of seven Chinese herbs that is being studied as a treatment for cancer.
- shoulder bladeOne of a pair of triangular bones at the back of the shoulder. The shoulder blade connects the collarbone...
- SHP-1 agonist SC-43An orally available, small molecule agonist of Src homology region 2 domain-containing phosphatase-1 (SHP-1...
- SHP2 inhibitor BBP-398An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor ERAS-601An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor ET0038An orally bioavailable allosteric inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2...
- SHP2 inhibitor HBI-2376An orally bioavailable small molecule inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11...
- SHP2 inhibitor HS-10381An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor JAB-3068An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor JAB-3312An orally bioavailable allosteric inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2...
- SHP2 inhibitor PF-07284892A small molecule inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src homology...
- SHP2 inhibitor RLY-1971An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor RMC-4630An orally bioavailable inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; Src...
- SHP2 inhibitor SH3809An orally bioavailable, small molecule inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11...
- Shu Di HuangA Chinese herbal medicine (CHM) containing the cooked or steamed root of the herbaceous plant Rehmannia...
- shu yu wan formulaA traditional Chinese medicine comprising different herbs that may be used for a variety of medical purposes...
- shuntIn medicine, a passage that is made to allow blood or other fluid to move from one part of the body to...
- Shwachman syndromeA rare, inherited disorder in which the pancreas and bone marrow do not work the way they should. Symptoms...
- Shwachman-Diamond syndromeA rare, inherited disorder in which the pancreas and bone marrow do not work the way they should. Symptoms...
- sialic acidAny of a group of simple sugar molecules.
- sialyl Lewisª-keyhole limpet hemocyanin conjugate vaccineA vaccine consisting of the oligosaccharide antigen sialyl Lewisª (CA19-9) conjugated to the nonspecific...
- sialyl Tn-KLHA vaccine composed of a substance that enhances immunity plus an antigen found on some tumors of the colon...
- siblingA person’s brother or sister who has the same parents.
- sickle cell anemiaAn inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels...
- sickle cell diseaseAn inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels...
- side effectAn effect of a drug or other type of treatment that is in addition to or beyond its desired effect. Side...
- sideropenic dysphagiaA disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that...
- sidestream smokeSmoke that comes from the lighted end of a burning tobacco product, such as a cigarette, pipe, or cigar...
- side-to-end coloanal anastomosisA surgical procedure in which the side of the colon is attached to the anus after the rectum has been...
- SIDSA disorder marked by the sudden and unexpected death of a healthy child who is younger than one year old...
- siG12D LODERA proprietary, miniature biodegradable polymeric matrix containing small-interfering RNAs for the mutated...
- sigmoid colonThe S-shaped section of the colon that connects to the rectum.
- sigmoidoscopeA thin, tube-like instrument used to examine the inside of the colon. A sigmoidoscope has a light and a lens...
- sigmoidoscopyExamination of the lower colon using a sigmoidoscope, inserted into the rectum. A sigmoidoscope is a thin...
- signIn medicine, a sign is something found during a physical exam or as a result of a laboratory or imaging test...
- signal transductionThe process by which a cell responds to substances outside the cell through signaling molecules found on the...
- signal transduction inhibitorA substance that blocks signals passed from one molecule to another inside a cell. Blocking these signals can...
- signaling pathwayDescribes a series of chemical reactions in which a group of molecules in a cell work together to control a...
- signature moleculeA biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal...
- signet ring cell carcinomaA highly malignant type of cancer typically found in glandular cells that line the digestive organs. The...
- significantIn statistics, describes a mathematical measure of difference between groups. The difference is said to be...
- SIK inhibitor OMX-0407An orally bioavailable inhibitor of the salt-inducible kinase 3 (SIK3), with potential antineoplastic and...
- SILAn abnormal growth of squamous cells that forms on the surface of certain organs, such as the cervix, vagina...
- silatecan AR-67A synthetic, highly lipophilic derivative of camptothecin, with potential antineoplastic and radiosensitizing...
- sildenafilA drug used to treat erectile dysfunction. Sildenafil relaxes the smooth muscle of the penis to allow...
- sildenafil citrateThe citrate salt form of sildenafil, an orally bioavailable pyrazolopyrimidinone derivative structurally...
- silevertinibAn orally bioavailable, brain penetrating, mutant-selective, epidermal growth factor receptor (EGFR)...
- silicon phthalocyanine 4A substance being studied in the treatment of cancer. When absorbed by cancer cells and exposed to light, it...
- siliconeA synthetic gel that is used as an outer coating on breast implants and as the inside filling of some...
- silicone-based film-forming topical gelA silicone-based film forming gel, with potential skin protective and healing activities. Upon topical...
- silmitasertibAn orally bioavailable small-molecule inhibitor of the enzyme casein kinase II (CK2), with potential...
- silmitasertib sodiumThe sodium salt of silmitasertib, an orally bioavailable small-molecule inhibitor of CK2 with potential...
- silodosinAn orally available, alpha-1 adrenoreceptor (alpha-1a) selective antagonist that can be used to relieve...
- siltuximabA drug used to treat a rare condition called multicentric Castleman disease in patients who do not have HIV...
- silver nitrateAn inorganic chemical with antiseptic activity. Silver nitrate can potentially be used as a cauterizing or...
- silver sulfadiazineA sulfonamide-based topical agent with antibacterial and antifungal activity. Silver sulfadiazine may act...
- Silybum marianumA plant that has been used in some cultures to treat certain medical problems, including stomach, liver, and...
- silymarinA substance obtained from milk thistle seeds that is being studied in the prevention of liver damage caused...
- simeprevirAn orally bioavailable inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural...
- simethiconeA mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the...
- simian virus 40A virus that infects some types of monkeys. It may also infect humans, and was found in some polio vaccines...
- simlukafusp alfaA recombinant fusion protein comprised of a human monoclonal antibody directed against fibroblast activation...
- simmiparibAn orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) 1 (PARP1) and 2...
- simmitecan hydrochlorideThe hydrochloride salt form of simmitecan, an ester prodrug of chimmitecan, a 9-alkyl substituted...
- simmitinibAn orally bioavailable inhibitor of numerous tyrosine kinases (TKs) including fibroblast growth factor...
- simo decoctionA traditional Chinese medicine (TCM) containing simo decoction which contains Fructus aurantii, Radix...
- simotaxelA semi-synthetic, orally bioavailable, third-generation taxane derivative and microtubule-stabilizing agent...
- simple fibroadenomaA type of benign (not cancer) tumor that usually forms in the breast and is made up of fibrous (connective)...
- simple hysterectomySurgery to remove the uterus and the cervix. The ovaries and fallopian tubes may also be removed. A simple...
- simple mastectomySurgery to remove the whole breast, which may include the nipple, areola (the dark-colored skin around the...
- simple nephrectomySurgery to remove one kidney.
- simple vulvectomySurgery to remove the entire vulva (the external female genital organs, including the clitoris, vaginal lips...
- simulationIn cancer treatment, a process used to plan radiation therapy so that the target area is precisely located...
- simvastatinA drug used to lower the amount of cholesterol and other harmful substances in the blood, such as...
- single nucleotide polymorphismThe most common type of change in DNA (molecules inside cells that carry genetic information). Single...
- single nucleotide variantA DNA sequence variation that occurs when a single nucleotide (adenine, thymine, cytosine, or guanine) in the...
- single-blind studyA type of clinical trial in which only the researcher doing the study knows which treatment or intervention...
- single-photon emission computed tomographyA special type of computed tomography (CT) scan in which a small amount of a radioactive drug is injected...
- SingulairA drug used to treat symptoms of asthma, such as trouble breathing, tight chest, wheezing, coughing, and...
- sintilimabA recombinant human monoclonal antibody directed against the negative immunoregulatory human cell surface...
- sinusA cavity, space, or channel in the body. Examples include hollow spaces in the bones at the front of the...
- sinusitisA condition in which the tissue lining the sinuses (small hollow spaces in the bones around the nose) becomes...
- sinusoidal obstruction syndromeA condition in which some of the veins in the liver are blocked. This causes a decrease in blood flow inside...
- sipjeondaebo-tangAn orally bioavailable east Asian herbal supplement, with potential gastro- and neuro-protective...
- siplizumabA substance being studied in the treatment of certain types of T-cell lymphoma. It is also being studied in...
- siponimod fumarateThe fumarate salt form of siponimod, an orally bioavailable sphingosine 1-phosphate (S1P) receptor modulator...
- Sipple syndromeA rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called...
- sipuleucel-TA vaccine used to treat prostate cancer that has spread to other parts of the body. It is used in patients...
- siremadlinAn orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity...
- sirexatamabA humanized monoclonal antibody directed against the WNT antagonist dickkopf homolog 1 (DKK1), with potential...
- siRNA-expressing SV40 vectorA simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential...
- siRNA-transfected peripheral blood mononuclear cells APN401Autologous peripheral blood mononuclear cells (PBMCs) transfected ex vivo with small-interfering ribonucleic...
- sirolimusA drug used to keep the body from rejecting organ and bone marrow transplants. Sirolimus blocks certain white...
- sirolimus protein-bound nanoparticlesThe macrolide antibiotic rapamycin bound to nanoparticle albumin with immunosuppressant (see sirolimus) and...
- sirolimus protein-bound particlesA form of the drug sirolimus that is used to treat adults with malignant perivascular epithelioid cell tumor...
- sirolimus topical gel NPC-12YA topical gel formulation containing the macrolide sirolimus (rapamycin), with potential anti-proliferative...
- sirolimus topical gel PTX-022A topical gel formulation containing the macrolide sirolimus (rapamycin), with potential anti-proliferative...
- SIRPa-4-1BBL fusion protein DSP107A bi-functional, trimeric, fusion protein consisting of the extracellular domains (ECDs) of human...
- SIRPa-Fc fusion protein TTI-621A soluble recombinant antibody-like fusion protein composed of the N-terminal CD47 binding domain of human...
- SIRPa-Fc-CD40L fusion protein SL-172154A bi-functional fusion protein consisting of the extracellular domains (ECDs) of human signal-regulatory...
- SIRP-alpha Fc fusion protein IMM01A recombinant fusion protein composed of human signal-regulatory protein alpha (SIRP-alpha; SIRPa; CD172a)...
- SIRP-alpha-Fc fusion protein HCB101A recombinant fusion protein composed of an extracellular domain of human signal-regulatory protein alpha...
- SIRPa-targeting agentAny agent that targets tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPalpha; SIRPa; CD172a).
- sirpiglenastatA broad acting glutamine antagonist, with potential immunomodulatory and antineoplastic activities. Upon...
- SIRSA serious condition in which there is inflammation throughout the whole body. SIRS may be caused by an...
- sirtratumab vedotinAn antibody-drug conjugate (ADC) composed of sirtratumab, a monoclonal antibody directed against SLIT and...
- sister chromatid exchangeMitotic crossover between homologous chromosomes.
- sisunatovirAn orally available, small molecule inhibitor of human respiratory syncytial virus (RSV) fusion protein (F...
- sitagliptin phosphateThe phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor...
- site specific immunomodulator QBECOA formulation composed of components of the inactivated bacteria Escherichia coli (E. coli), with potential...
- SitravatinibAn orally bioavailable, receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Upon...
- sivifene gelThe phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with...
- six TAAs-specific autologous T cells MT-601A preparation of autologous, ex vivo-expanded, CD4- and CD8-positive T lymphocytes specific for six...
- sizofiranA soluble beta-D-glucan produced by the Basidiomycetes fungus, Schizophyllum commune Fries, with potential...
- SJG-136A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called DNA...
- Sjögren syndromeAn autoimmune disease that affects the tear glands and salivary glands, and may affect glands in the stomach...
- skeletalHaving to do with the skeleton (bones of the body).
- skeletonThe framework that supports the soft tissues of vertebrate animals and protects many of their internal...
- SK&F106615A substance being studied in the treatment of certain multiple myelomas and other advanced cancers...
- skin cancerCancer that forms in the tissues of the skin. There are several types of skin cancer. Skin cancer that forms...
- skin conductionA change in the heat and electricity passed through the skin by nerves and sweat. Skin conduction increases...
- skin graftSkin that is moved from one part of the body to another.
- skin patchA bandage-like patch that releases medicine into the body through the skin. The medicine enters the blood...
- skin stimulationThe process of applying pressure, friction, temperature change, or chemical substances to the skin to lessen...
- skin tagA common benign (not cancer) skin growth that appears as a small, raised, brown or skin-colored bump that may...
- skin testA test for an immune response to a compound by placing it on or under the skin.
- skin vesicleA fluid-filled sac in the outer layer of skin. It can be caused by rubbing, heat, or diseases of the skin...
- skinning vulvectomySurgery to remove the top layer of skin of the vulva (the external female genital organs, including the...
- skullThe bones that form the head. The skull is made up of cranial bones (bones that surround and protect the...
- SL-11047A substance that is being studied in the treatment of lymphoma. It belongs to the family of drugs called...
- SLC24A5 geneA gene that makes a protein involved in giving color to the skin, hair, and eyes. Mutations (changes) in the...
- SLC45A2 geneA gene that makes a protein involved in making melanin (a pigment that gives color to the skin, hair, and...
- SLC6A8 inhibitor RGX-202An orally available, small molecule inhibitor of the creatine transporter, solute carrier family 6, member 8...
- SLEA chronic, inflammatory, connective tissue disease that can affect many organs including the joints, skin...
- sleep apneaA sleep disorder that is marked by pauses in breathing of 10 seconds or more during sleep, and causes...
- sleep disorderA disturbance of normal sleep patterns. There are a number of sleep disorders that range from trouble falling...
- sleep stageOne of four stages of the sleep cycle based on the type of brain activity that occurs during the stage...
- sleeve lobectomySurgery to remove a lung tumor in a lobe of the lung and a part of the main bronchus (airway). The ends of...
- sleeve resectionSurgery to remove a lung tumor in a lobe of the lung and a part of the main bronchus (airway). The ends of...
- SLFN12-PDE3A complex inducer BAY 2666605An orally bioavailable agent that triggers the formation of a complex of the two proteins Schlafen family...
- slippery elmThe inner bark of this plant has been used in some cultures to treat certain medical problems. It may have...
- slit-lamp biomicroscopyAn eye exam using an instrument that combines a low-power microscope with a light source that makes a narrow...
- slit-lamp eye examAn eye exam using an instrument that combines a low-power microscope with a light source that makes a narrow...
- SLLAn indolent (slow-growing) type of lymphoma in which too many immature lymphocytes (white blood cells) are...
- Smac mimetic BGB-24714An orally bioavailable mimetic of the natural second mitochondrial-derived activator of caspases (Smac), with...
- SMAC mimetic BI 891065A mimetic of second mitochondrial-derived activator of caspases (Smac/DIABLO) and inhibitor of IAPs...
- Smac mimetic CUDC-427An orally available, monovalent mimetic of second mitochondrial-derived activator of caspases (Smac/DIABLO)...
- Smac mimetic GDC-0152A second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis...
- SMAC mimetic LCL161An orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP...
- SM-AHNA rare condition in which too many mast cells (a type of white blood cell) build up in certain tissues and...
- small cell carcinomaA fast-growing type of cancer that usually occurs in the lungs but may also occur in many other parts of the...
- small cell lung cancerAn aggressive (fast-growing) cancer that forms in tissues of the lung and can spread to other parts of the...
- small intestineA long tube-like organ that connects the stomach and the large intestine. It is about 20 feet long and folds...
- small intestine cancerA rare cancer that forms in tissues of the small intestine (a long tube-like organ that connects the stomach...
- small lymphocytic lymphomaAn indolent (slow-growing) type of lymphoma in which too many immature lymphocytes (white blood cells) are...
- small-molecule drugA drug that can enter cells easily because it has a low molecular weight. Once inside the cells, it can...
- SMARCA2 degrader PRT3789A targeted protein degrader (TPD) of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin...
- SMARCA2 degrader PRT7732An orally bioavailable targeted protein degrader (TPD) of SWI/SNF-related matrix-associated actin-dependent...
- SMO antagonist BMS 833923An orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity. SMO...
- SMO protein inhibitor ZSP1602An orally bioavailable small molecule SMO (Smoothened) inhibitor with potential antineoplastic activity. SMO...
- smoked plumThe fruit of the Prunus mume tree that is used as a traditional Chinese medicine (TCM) called Wu Mei, which...
- smokeless tobaccoA type of tobacco that is not smoked or burned. It may be used as chewing tobacco or moist snuff, or inhaled...
- smoking cessationTo quit smoking. Smoking cessation lowers the risk of cancer and other serious health problems. Counseling...
- smoldering myelomaA very slow-growing type of myeloma in which abnormal plasma cells (a type of white blood cell) make too much...
- Smoothened antagonist LDE225 topicalA topical formulation of the small-molecule Smoothened (Smo) antagonist LDE225 with potential antineoplastic...
- Smoothened antagonist LEQ506An orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity...
- Smoothened antagonist TAK-441An orally bioavailable pyrrolopyridine derivative and Smoothened (Smo) antagonist with potential...
- SN-38 liposomeA form of the anticancer drug irinotecan that is contained in very tiny, fat-like particles. It may have...
- SN-38-loaded polymeric micelles NK012A formulation consisting of polymeric micelles loaded with the irinotecan metabolite SN-38 with potential...
- SNDX-275A substance being studied in the treatment of several types of cancer. It blocks enzymes needed for cell...
- SnET2An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called...
- SNPThe most common type of change in DNA (molecules inside cells that carry genetic information). SNPs occur...
- SNRIA type of drug that is used to treat depression and some other conditions. SNRIs stop or delay substances...
- SNS01-T nanoparticlesA colloidal mixture of nanoparticles consisting of small interfering RNA (siRNA) targeting the native...
- snuff tobaccoA type of smokeless tobacco that is made of finely ground or shredded tobacco leaves. It may have different...
- SNVA DNA sequence variation that occurs when a single nucleotide (adenine, thymine, cytosine, or guanine) in the...
- SNX 111A drug used in the treatment of chronic pain. Also called Prialt and ziconotide.
- SNX-5422A substance being studied in the treatment of cancer. SNX-5422 blocks a protein needed for cells to grow and...
- SNX-5422 mesylateA substance being studied in the treatment of cancer. SNX-5422 mesylate blocks a protein needed for cells to...
- soblidotinA substance being studied in the treatment of cancer. It is a type of tubulin inhibitor. Also called TZT-1027.
- social determinants of healthThe social, economic, and physical conditions in the places where people are born and where they live, learn...
- social serviceA community resource that helps people in need. Services may include help getting to and from medical...
- social supportA network of family, friends, neighbors, and community members that is available in times of need to give...
- social workerA professional trained to talk with people and their families about emotional or physical needs, and to find...
- socioeconomic statusA way of describing people based on their education, income, and type of job. Socioeconomic status is usually...
- SOD1 inhibitor ATN-224A substance being studied in the treatment of cancer. It may prevent the growth of new blood vessels that...
- sodiumA mineral needed by the body to keep body fluids in balance. Sodium is found in table salt and in many...
- sodium alginate microspheresAn embolic agent containing microporous hydrospheres of sodium alginate with potential arterial occlusive...
1,286 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.