MLchartDataset catalogue

siRNA-expressing SV40 vector

Term · Oncology and biomedicine · MLC-T-ONC-016751

A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity. The expression of siRNA in target tumor cells transfected with an siRNA-expressing SV40 vector may result in siRNA-mediated silencing of target oncogenes and, so, the inhibition of tumor cell growth and the induction of tumor cell death.

Table 1. Record
IdentifierMLC-T-ONC-016751
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-016751",
  "term": "siRNA-expressing SV40 vector",
  "field": "Oncology and biomedicine",
  "definition": "A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity. The expression of siRNA in target tumor cells transfected with an siRNA-expressing SV40 vector may result in siRNA-mediated silencing of target oncogenes and, so, the inhibition of tumor cell growth and the induction of tumor cell death.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sirna-expressing-sv40-vector/"
}

Record 15,030 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.