Oncology and biomedicine terminology · MLC-0111
Oncology and biomedicine terms: G (582)
- G. lucidum/A. blazei/G. frondosa/H. erinaceus/C. sinensis/I. obliquus/P. ostreatus/P. umbellatus/ L. edodes supplementA dietary supplement composed of fungal extracts of Ganoderma lucidum, Agaricus blazei, Grifola frondosa...
- G protein-coupled estrogen receptor agonist LNS8801An orally bioavailable selective agonist of the G protein-coupled estrogen receptor (G protein-coupled...
- G207A neuroattenuated, replication-competent, recombinant herpes simplex virus-1 (HSV-1) with potential oncolytic...
- G250 peptide vaccineA cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250...
- G6PD deficiencyAn inherited disorder in which a person doesn’t have enough of an enzyme called G6PD that helps red blood...
- Ga-68-labeled F(ab') 2- trastuzumabA radioimmunoconjugate consisting of a trastuzumab fragment labeled with the positron-emitting radioisotope...
- gabapentinA substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It...
- GADA condition marked by excessive worry and feelings of fear, dread, and uneasiness that last six months or...
- gadobenate dimeglumineA drug used in MRI to help make clear pictures of blood vessels in the brain, spine, and nearby tissues. It...
- gadobutrolA gadolinium-based, hydrophilic, macrocyclic, electrically neutral contrast agent used in contrast-enhanced...
- gadodiamideA paramagnetic gadolinium-based contrast agent (GBCA), with imaging activity upon magnetic resonance imaging...
- gadofosveset trisodiumThe trisodium salt form of gadofosveset, an injectable, intravascular, amphiphilic gadolinium-based contrast...
- gadoliniumA metal element that is used in magnetic resonance imaging (MRI) and other imaging methods. It is a contrast...
- gadolinium texaphyrinA substance being studied in the treatment and diagnosis of some types of cancer. It builds up in some cancer...
- gadolinium-based contrast agent BAY1747846A gadolinium (Gd)-based contrast agent (GBCA) that can potentially be used for contrast-enhanced MRI...
- gadolinium-chelateA coordination complex consisting of a gadolinium ion bound to a hexadentate organic chelating agent such as...
- gadopentetate dimeglumineA substance used in magnetic resonance imaging (MRI) to help make clear pictures of the brain, spine, heart...
- gadopiclenolA gadolinium-based paramagnetic contrast agent, with potential imaging enhancing activity upon magnetic...
- gadoterate meglumineA gadolinium chelate paramagnetic contrast agent. When placed in a magnetic field, gadoterate meglumine...
- Gadoxetate DisodiumA paramagnetic contrast agent consisting of the disodium salt of the gadolinium ion chelated with the...
- Gag:267-274 peptide vaccineA peptide vaccine containing the amino acids 267 through 274 of the human immunodeficiency virus type 1...
- Gail modelA computer program that uses personal and family medical history information to estimate a woman’s chance of...
- Gail risk modelA computer program that uses personal and family medical history information to estimate a woman’s chance of...
- galactographyA procedure that uses x-rays to create pictures of milk ducts in the breast. A very thin catheter (tube) is...
- galactomannan derivativeA carbohydrate polymer composed of mannose and galactose, with chemotherapeutic enhancing activity...
- galacto-oligosaccharide prebiotic supplementA nutritional supplement containing fibers and galacto-oligosaccharides (GOS), with potential...
- galactoseA hexose which is almost identical to glucose except that orientation of -H and -OH on carbon 4 are...
- galantamine hydrobromideThe hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the...
- galectin-1 inhibitor OTX008A calixarene-based compound and galectin-1 (Gal-1) inhibitor with potential anti-angiogenic and...
- galeteroneAn orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential...
- galinpepimut-SA peptide cancer vaccine comprised of four peptide chains derived from the Wilms’ tumor gene 1 (WT1) protein...
- galiximabA substance being studied in the treatment of follicular non-Hodgkin lymphoma. It binds to the protein CD80...
- gallbladderThe pear-shaped organ found below the liver. Bile is concentrated and stored in the gallbladder.
- gallbladder cancerCancer that forms in tissues of the gallbladder. The gallbladder is a pear-shaped organ below the liver that...
- gallium citrate Ga 67The citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67...
- gallium Ga 68 AIP-301A radioconjugate composed of AIP-301, a molecule targeting the tumor-associated antigen (TAA) epidermal...
- gallium Ga 68 EB-ss-CPTA radioconjugate composed of the amphiphilic camptothecin (CPT) prodrug EB-ss-CPT, labeled with the...
- gallium Ga 68 FAP-2286A radioconjugate composed of FAP-2286, a fibroblast activation protein (FAP)-targeted peptide, attached to a...
- gallium Ga 68 FAP-CHXA radioconjugate composed of FAP-CHX, a fibroblast activation protein (FAP)-targeted tracer, labeled with the...
- gallium Ga 68 FAPi-46A radioconjugate composed of FAPi-46, a quinoline-based fibroblast activation protein (FAP)-targeted tracer...
- gallium Ga 68 FF58A radiopharmaceutical agent comprised of FF58, a non-arginine-glycine-aspartic acid (Arg-Gly-Asp/RGD) small...
- gallium Ga 68 gozetotideA radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand...
- gallium Ga 68 labeled PSMA-targeting radiodiagnostic agent HRS-9815A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting agent labeled with...
- gallium Ga 68 N188A radioconjugate composed of a nectin-4 (poliovirus receptor-like 4; PVRL4)-targeting moiety, labeled with...
- gallium Ga 68 NNS309A radioconjugate composed of NNS309, which targets an as of yet unelucidated target on tumor cells, that is...
- gallium Ga 68 NODAGA-CBP8A radiotracer composed of CBP8, a collagen-targeting peptide, linked via a tris(tert-butyl) ester-protected...
- gallium Ga 68 NY104A radioconjugate composed of NY104, a small molecule carbonic anhydrase IX (CAIX; carbonic anhydrase 9; CA9...
- gallium Ga 68 P3A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand, P3, labeled...
- gallium Ga 68 R8760A radioconjugate composed of a melanocortin 2 receptor (MC2R; adrenocorticotropic hormone receptor...
- gallium Ga 68 satoreotide tetraxetanA radioconjugate consisting of the somatostatin antagonistic peptide satoreotide that is linked via the...
- gallium Ga 68 satoreotide trizoxetanA radioconjugate consisting of the somatostatin antagonistic peptide OPS202 that is labeled with the...
- gallium Ga 68-citrateA radiopharmaceutical citrate salt form of the positron-emitting radioisotope gallium Ga 68, with potential...
- gallium Ga 68/copper Cu 64-labeled FAPI-XT117A radioconjugate composed of FAPI-XT117, a fibroblast activation protein inhibitor (FAPi), labeled with the...
- gallium Ga 68-DOTA-5GA radioconjugate composed of 5G, an agent targeting an as of yet undisclosed target, conjugated, via the...
- gallium Ga 68-DOTA-exendin-4A radiopharmaceutical composed of the glucagon-like peptide 1 receptor (GLP-1R) agonist exendin-4 linked by...
- gallium Ga 68-DOTA-FAPI-04A radioconjugate composed of FAPI-04, a quinoline-based fibroblast activation protein (FAP)-targeted tracer...
- gallium Ga 68-DOTA-MGS5A radioconjugate consisting of the minigastrin analog, MGS5, conjugated, via the bifunctional, macrocyclic...
- gallium Ga 68-DOTANOCA gallium Ga 68-radiolabeled analogue of somatostatin that may be used in conjunction with positron emission...
- gallium Ga 68-DOTA-siglec-9A radiopharmaceutical composed of the sialic acid binding Ig-like lectin 9 (siglec-9) linked by the...
- gallium Ga 68-DOTATATEA radioconjugate consisting of the somatostatin analogue tyrosine-3-octreotate (Tyr3-octreotate or TATE)...
- gallium Ga 68-edotreotideA radioconjugate consisting of the octreotide derivative edotreotide labeled with gallium 68 (Ga-68) with...
- gallium Ga 68-EVS459A radioconjugate composed of EVS459, a folate receptor alpha (FRa; FolRa; FOLR1)-targeting moiety...
- gallium Ga 68-HA-DOTA-TATEA radioconjugate consisting of consisting of the high affinity somatostatin analogue...
- gallium Ga 68-HBED-CC-exendin-4A radiopharmaceutical composed of the glucagon-like peptide 1 receptor (GLP-1R) agonist exendin-4 linked by...
- gallium Ga 68-ICAM-1pepA radioconjugate composed of ICAM-1pep, an intercellular adhesion molecule-1 (ICAM-1; CD54)-targeted tracer...
- gallium Ga 68-labeled affibody ABY-025A radioconjugate composed of an optimized affibody conjugated, via its C-terminal cysteine, to...
- gallium Ga 68-labeled alphaVbeta6 binding peptide RAD 301A radiotracer composed of RAD301, which comprises an integrin alphaVbeta6 (aVb6) binding peptide (BP) and is...
- gallium Ga 68-labeled BNOTA-PRGD2A radiopharmaceutical agent comprised of a pegylated arginine-glycine-aspartic acid dimer (PRGD2) labeled...
- gallium Ga 68-labeled DOTA Di-HSG peptide IMP-288A radiolabeled divalent histamine-succinyl-glycine (HSG) hapten-peptide linked with the macrocyclic chelator...
- gallium Ga 68-labeled DX600A radioconjugate composed of an angiotensin converting enzyme 2 (ACE2)-specific inhibitor DX600 labeled with...
- gallium Ga 68-labeled MLN6907A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the...
- gallium Ga 68-labeled NODAGA-MJ9A radiopharmaceutical agent comprised of a peptide targeting the gastrin releasing peptide receptor (GRPR)...
- gallium Ga 68-labeled RM2A radioconjugate containing a synthetic bombesin receptor antagonist targeting the gastrin-releasing peptide...
- gallium Ga 68-labeled tilmanoceptA radioconjugate composed of tilmanocept, a macromolecule consisting of multiple units of mannose and the...
- gallium Ga 68-NEBA radiotracer composed of a truncated form of the azo dye Evans blue (EB) conjugated, via a...
- gallium Ga 68-NeoBA radioconjugate consisting of a gastrin-releasing peptide receptor (GRPR) antagonist linked via the...
- gallium Ga 68-NODAGA-Ac-Cys-ZEGFR:1907A radiolabeled recombinant EGFR-specific affibody molecule composed of an epidermal growth factor receptor...
- gallium Ga 68-NODAGA-E(c[RGDyK])2A radiopharmaceutical agent composed of a dimeric cyclic arginine-glycine-aspartic acid (RGD)-based peptide...
- gallium Ga 68-NODAGA-LM3A radiopharmaceutical agent comprised of LM3, a human somatostatin receptor (SSTR) antagonist, chelated with...
- gallium Ga 68-NODAGA-ZIGF-1R:4:40A radiolabeled recombinant insulin-like growth factor 1 receptor (IGF-1R; IGF1R)-specific affibody ligand...
- gallium Ga 68-NOTA-3PTATE-RGDA radiopharmaceutical agent composed of a modified form of the somatostatin analogue octreotate (TATE)...
- gallium Ga 68-NOTA-Aca-BBN(7-14)A radioconjugate containing the bombesin (BBN) fragment BBN(7-14) comprised of the amino acid sequence of...
- gallium Ga 68-NOTA-AE105A radiotracer composed of AE105, an urokinase-type plasminogen activator receptor (uPAR) peptide antagonist...
- gallium Ga 68-NOTA-anti-HER2 nanobody VHH1A radioconjugate composed of a nanobody directed against human epidermal growth factor receptor 2 (HER2...
- gallium Ga 68-NOTA-anti-MMR-VHH2 nanobodyA radiotracer composed of a nanobody against the macrophage mannose receptor (MMR, CD206) conjugated with the...
- gallium Ga 68-NOTA-BBN-RGDA radioconjugate containing the bombesin (BBN) fragment BBN(7-14) comprised of the amino acid sequence...
- gallium Ga 68-NOTA-exendin-4A radiopharmaceutical composed of the glucagon-like peptide 1 receptor (GLP-1R) agonist exendin-4 linked by...
- gallium Ga 68-NOTA-FAPI-04A radioconjugate composed of FAPI-04, a quinoline-based fibroblast activation protein (FAP)-targeted tracer...
- gallium Ga 68-NOTA-hGZPA radiotracer composed of hGZP, a biotinylated human granzyme B peptide, conjugated with the bifunctional...
- gallium Ga 68-NOTA-MAL-Cys39-exendin-4A radiopharmaceutical tracer composed of the glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 in...
- gallium Ga 68-NOTA-NFBA radioconjugate composed of a derivative of the CXCR4 peptide antagonist T140, in which the N-terminal...
- gallium Ga 68-NOTA-RM26A radioconjugate containing RM26, a synthetic bombesin analogue and antagonist of the gastrin-releasing...
- gallium Ga 68-NOTA-Sgc8A radioconjugate consisting of Sgc8, a 41 oligonucleotides long single-stranded DNA aptamer and protein...
- gallium Ga 68-NOTA-SNA002A radiotracer composed of SNA002, a targeting agent for programmed cell death-1 ligand 1 (PD-L1; cluster of...
- gallium Ga 68-P15-041A radiotracer composed of a bone targeting agent P15-041 linked to the radioisotope gallium Ga 68, with...
- gallium Ga 68-P16-093A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand (P16-093)...
- gallium Ga 68-pentixaforA radioconjugate composed of a synthetic, cyclic pentapeptide analog of stromal-cell derived factor-1 (SDF-1...
- gallium Ga 68-PNT6555A radioconjugate composed of PNT6555, a fibroblast activation protein (FAP)-targeting moiety linked to the...
- gallium Ga 68-PSMA-617A radioconjugate composed of PSMA-617, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
- gallium Ga 68-PSMA-R2A radioconjugate composed of PSMA-R2, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
- gallium Ga 68-R10602A radioconjugate containing a small molecule radioligand targeting an as of yet undisclosed hormone receptor...
- gallium Ga 68-RGDA radiopharmaceutical agent comprised of a cyclic arginine-glycine-aspartic acid (Arg-Gly-Asp/RGD) peptide...
- gallium Ga 68-THP-PSMAA radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting agent conjugated...
- gallium Ga 68-VMT02A radioconjugate composed of the melanocyte-stimulating hormone receptor (MSHR; melanocortin-1 receptor...
- gallium Ga 68-WL12A radiotracer composed of the programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274...
- gallium Ga-labeled PSMA-11-gadoxetateA radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand...
- gallium maltolateAn orally bioavailable form of the element gallium (Ga) composed of a trivalent gallium cation (Ga3+)...
- gallium nitrateA drug that lowers blood calcium. Used as treatment for hypercalcemia (too much calcium in the blood) and for...
- gallium scanA procedure to detect areas of the body where cells are dividing rapidly. It is used to locate cancer cells...
- gallium-based bone resorption inhibitor AP-002An orally bioavailable gallium (Ga)-based small molecule agent with potential anti-bone resorption and...
- gallstoneSolid material that forms in the gallbladder or common bile duct. Gallstones are made of cholesterol or other...
- galunisertibAn orally available, small molecule antagonist of the tyrosine kinase transforming growth factor-beta (TGF-b)...
- galvanic skin responseA change in the heat and electricity passed through the skin by nerves and sweat. Galvanic skin response...
- gamboge resin extract TSB-9-W1An orally bioavailable extract from the yellow to brown gum-resin of the gamboge tree (genus Garcinia)...
- gameteAn egg cell in females or sperm cell in males. Each mature gamete contains 23 chromosomes. When an egg...
- GamifantA drug used to treat a rare immune system disorder called primary hemophagocytic lymphohistiocytosis (HLH)...
- gamitrinibA resorcinolic-based mitochondrial-targeted heat shock protein 90 (Hsp90) family inhibitor, with potential...
- gamma irradiationA type of radiation therapy that uses gamma radiation. Gamma radiation is a type of high-energy radiation...
- Gamma Knife therapyA treatment using gamma rays, a type of high-energy radiation that can be tightly focused on small tumors or...
- gamma rayA type of high-energy radiation that is different from an x-ray.
- gamma secretaseA protein complex found in the cell membrane that has an enzyme that cuts proteins, such as Notch and APP...
- gamma secretase inhibitorA substance that blocks the enzyme activity of a protein complex called gamma secretase. Gamma secretase is...
- gamma-delta tocotrienolAn orally available nutritional supplement containing the gamma and delta forms of the vitamin E family...
- gamma-secretase/Notch signalling pathway inhibitor RO4929097An orally bioavailable, small-molecule gamma secretase (GS) inhibitor with potential antitumor activity...
- gamma-tocopherolThe orally bioavailable gamma form of the naturally-occurring fat-soluble vitamin E, found in certain nuts...
- ganaxoloneAn orally bioavailable synthetic analog of the neuroactive steroid allopregnanolone and positive allosteric...
- ganciclovirAn antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body's immune...
- gandotinibAn orally bioavailable imidazopyridazine and inhibitor of Janus kinase 2 mutant V617F (JAK2V617F), with...
- ganetespibA substance being studied in the treatment of some types of cancer. Ganetespib blocks the activity of a...
- gangliosideA complex molecule that contains both lipids (fats) and carbohydrates (sugars) and is found in the plasma...
- ganitumabA recombinant, fully human monoclonal antibody directed against the insulin-like growth factor 1 receptor...
- Ganoderma lucidum spores powder capsuleAn orally available powder-based nutritional supplement containing the spores of the mushroom Ganoderma...
- GAPPSA rare, inherited disorder in which many polyps (usually hundreds) form in the lining of the upper part of...
- GardasilA vaccine that is no longer available in the United States but is still used in other countries to protect...
- Gardasil 9A vaccine that is FDA-approved for use in females and males aged 9 to 45 years to protect against infection...
- garden heliotropeA plant whose roots are used as a sedative and to treat certain medical conditions. It is being studied as a...
- garden valerianA plant whose roots are used as a sedative and to treat certain medical conditions. It is being studied as a...
- Gardner syndromeA rare, inherited disorder in which many polyps (abnormal growths of tissue) form on the inner walls of the...
- garetatug rezetecanAn antibody-drug conjugate (ADC) composed of garetatug, an immunoglobulin G1 (IgG1) monoclonal antibody...
- garlicA European plant that has a bulb used to flavor food. It has also been used in some cultures to treat certain...
- garlic extractThe alcoholic extract of the bulb or whole garlic plant Allium sativum (Liliaceae) with potential...
- garsorasibAn orally available inhibitor of the oncogenic KRAS substitution mutation, G12C, with potential...
- gastrectomyAn operation to remove all or part of the stomach.
- gastricHaving to do with the stomach.
- gastric acidAcid that is released into the stomach from glands in the stomach wall. It helps digest food. Gastric acid is...
- gastric acid secretion testA test used to measure the amount of gastric acid made by the stomach. The patient receives an injection of...
- gastric adenocarcinoma and proximal polyposis of the stomachA rare, inherited disorder in which many polyps (usually hundreds) form in the lining of the upper part of...
- gastric atrophyA condition marked by thinning of the inner lining of the stomach wall and the loss of gland cells in the...
- gastric cancerCancer that forms in tissues lining the stomach. Also called stomach cancer.
- gastric cardia cancerA type of stomach cancer that begins in the mucous-producing cells in the inner lining of the cardia (the...
- gastric feeding tubeA tube that is inserted through the nose, down the throat and esophagus, and into the stomach. It can be used...
- gastric mucosal hypertrophyA condition marked by inflammation and ulcers (breaks on the skin or on the surface of an organ) of the...
- gastric refluxThe backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the...
- gastric scirrhous carcinomaA rare type of stomach cancer that begins in the lining of the stomach and spreads to the muscles of the...
- gastrinA hormone released from special cells in the lining of the stomach after eating. Gastrin causes the stomach...
- gastrin immunotoxinAn immunotoxin containing an epitope of human gastrin conjugated to diphtheria toxin, with antineoplastic...
- gastrinomaA tumor that causes overproduction of gastric acid. It usually begins in the duodenum (first part of the...
- gastritisInflammation of the lining of the stomach.
- gastroenteritisInflammation of the lining of the stomach and the intestines. Symptoms may include nausea, vomiting...
- gastroenterologistA doctor who has special training in diagnosing and treating disorders of the digestive system.
- gastroenteropancreatic neuroendocrine tumorA rare type of tumor that can form in the pancreas or in other parts of the gastrointestinal tract, including...
- gastroesophageal junctionThe place where the esophagus is connected to the stomach.
- gastroesophageal refluxThe backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the...
- gastrointestinalHaving to do with the gastrointestinal (GI) tract or GI system. The GI tract includes the mouth, throat...
- gastrointestinal carcinoid tumorA rare, slow-growing type of cancer that forms in the lining of the gastrointestinal (GI) tract, usually in...
- gastrointestinal neuroendocrine tumorA rare, slow-growing type of cancer that forms in the lining of the gastrointestinal (GI) tract, usually in...
- gastrointestinal stromal tumorA type of tumor that usually begins in cells in the wall of the gastrointestinal tract. Some gastrointestinal...
- gastrointestinal systemThe organs that take in food and liquids and break them down into substances that the body can use for...
- gastrointestinal tractThe organs that food and liquids travel through when they are swallowed, digested, absorbed, and leave the...
- gastrojejunostomyA surgical procedure that connects part of the stomach to the jejunum (the middle part of the small...
- gastroscopeA thin, tube-like instrument used to examine the inside of the stomach. A gastroscope has a light and a lens...
- gastrostomy tubeA tube inserted through the wall of the abdomen directly into the stomach. It allows air and fluid to leave...
- gataparsen sodiumA second-generation antisense oligonucleotide directed against survivin mRNA with potential antitumor...
- gatipotuzumabA humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1), with potential...
- gavageA way of giving medicines and liquids, including liquid foods, through a small tube placed through the nose...
- gavilimomabA murine IgM monoclonal antibody (MoAb) developed for the potential treatment of graft versus host disease...
- gavocabtagene autoleucelA preparation of autologous T lymphocytes that have been genetically engineered to express a single-domain...
- GavretoA drug used to treat adults with non-small cell lung cancer that has a RET fusion gene and has spread to...
- GazyvaA drug used with other drugs to treat certain types of follicular lymphoma and chronic lymphocytic leukemia...
- GBMA fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain...
- GBM antigens and alloantigens immunotherapeutic vaccineAn orally bioavailable, immunotherapeutic vaccine composed of hydrolyzed and formulated glioblastoma...
- GBSA rare condition in which the body’s immune system attacks the nerves located outside the brain and spinal...
- GC1008A substance being studied in the treatment of breast cancer that has spread to other parts of the body. It is...
- GCN2 inhibitor APL-4098An orally bioavailable inhibitor of the serine/threonine protein kinase general control nonderepressible 2...
- GCN2 modulator HC-7366-KAn immediate release (IR) capsule formulation of the potassium salt monohydrate form of HC-7366, a modulator...
- GCPAn international set of guidelines that helps make sure that the results of a clinical trial are reliable and...
- G-CSFA drug used under the brand names Neupogen, Zarxio, and Nivestym to treat neutropenia (a lower-than-normal...
- GCTA rare tumor that usually forms in bone, but may also form in cartilage, muscle, fat, blood vessels, or other...
- GD2 lactone/GD3 lactone-KLH conjugate bivalent vaccineA cancer vaccine, containing epitopes of the gangliosides GD2 and GD3 conjugated with the immunostimulant...
- GD2-CAR-expressing autologous T-lymphocytesGenetically modified, autologous T-lymphocytes transduced with a retroviral vector encoding a 14g2a.zeta...
- GDC-0449A drug used to treat basal cell carcinoma that has spread to other parts of the body, has come back after...
- Gd-DTPAA substance used in magnetic resonance imaging (MRI) to help make clear pictures of the brain, spine, heart...
- gebasaxturevA preparation of naturally occurring, oncolytic enterovirus, with potential antineoplastic activity. Upon...
- gedatolisibAn agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the...
- gefitinibA drug used to treat non-small cell lung cancer that has spread to other parts of the body and has certain...
- gefurulimabA humanized bispecific VHH antibody directed against terminal complement protein C5 and albumin, with...
- gel electrodeA device that uses a gel to carry an electric current from the skin to a measuring instrument. A sticky patch...
- GelclairA gel used to lessen pain from mouth sores caused by chemotherapy or radiation therapy, oral surgery, braces...
- geldanamycin analogAn antineoplastic antibiotic drug that belongs to the family of drugs called ansamycins.
- geloninA class I ribosome-inactivating protein (RIP) and toxin derived from the seeds of the plant Gelonium...
- GEM 231A drug that may inhibit the growth of malignant tumors.
- GEM640A substance being studied in the treatment of cancer. GEM640 may kill cancer cells by blocking the production...
- gemcitabine 5'-elaidic acid esterA lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite...
- gemcitabine hydrochlorideA drug used alone or with other drugs to treat certain types of breast, non-small cell lung, ovarian, and...
- gemcitabine hydrochloride emulsionAn orally available nanoparticle-based formulation containing the hydrochloride salt form of gemcitabine, a...
- gemcitabine liposome FF-10832A liposomal formulation in which gemcitabine, a broad-spectrum antimetabolite and deoxycytidine analogue, is...
- gemcitabine prodrug LY2334737An orally available valproic acid ester of gemcitabine, a broad-spectrum antimetabolite with antineoplastic...
- gemcitabine-cisplatinA chemotherapy combination used to treat malignant mesothelioma, advanced non-small cell lung cancer...
- gemcitabine-cisplatin regimenA chemotherapy combination used to treat malignant mesothelioma, advanced non-small cell lung cancer...
- gemcitabine-erlotinib regimenA chemotherapy combination used for the treatment of locally advanced and metastatic pancreatic cancer. It...
- gemcitabine-oxaliplatinA chemotherapy combination used to treat pancreatic cancer and some other types of cancer. It includes the...
- gemcitabine-oxaliplatin regimenA chemotherapy combination used to treat pancreatic cancer and some other types of cancer. It includes the...
- gemcitabine-releasing intravesical systemA controlled-release intravesical system consisting of a small flexible tube-like device with a solid core...
- gemcitabine-Tarceva regimenA chemotherapy combination used for the treatment of locally advanced and metastatic pancreatic cancer. It...
- gemfibrozilA fibric acid derivative with hypolipidemic effects. Gemfibrozil interacts with peroxisome...
- gemigliptinAn orally bioavailable inhibitor of the serine protease dipeptidyl peptidase 4 (DPP-4), with hypoglycemic and...
- gemogenovatucel-TAutologous tumor cells transfected with a plasmid expressing recombinant human granulocyte macrophage-colony...
- GEMOXA chemotherapy combination used to treat pancreatic cancer and some other types of cancer. It includes the...
- gemtuzumab ozogamicinA drug used alone or with other drugs to treat acute myeloid leukemia that is CD33 positive (expresses the...
- GemzarA drug used alone or with other drugs to treat certain types of breast, non-small cell lung, ovarian, and...
- GenasenseA substance being studied in the treatment of cancer. It may kill cancer cells by blocking the production of...
- geneThe functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and...
- gene amplificationAn increase in the number of copies of a gene. There may also be an increase in the RNA and protein made from...
- gene deletionThe loss of all or a part of a gene. There may also be a change in the RNA and protein made from that gene...
- gene expressionThe process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be...
- gene expression profileInformation about all of the genes in a cell or tissue that are making messenger RNA. Messenger RNA molecules...
- gene signatureInformation about the activity of a specific group of genes in a cell or tissue. In cancer, gene signatures...
- gene therapyAn experimental treatment that adds a new gene or replaces or repairs a mutated (changed) gene inside the...
- gene transferThe insertion of genetic material into a cell.
- gene-edited autologous neoantigen-targeted NeoTCR-P1 T cellsA preparation of autologous CD4- and CD8-positive T lymphocytes that have been engineered with site-specific...
- gene-modifiedCells that have been altered to contain different genetic material than they originally contained.
- gene-modified HIV-protected hematopoietic stem cellsAutologous hematopoietic stem cells (HSCs) genetically modified to be resistant to infection by human...
- general anesthesiaA temporary loss of feeling and a complete loss of awareness that feels like a very deep sleep. It is caused...
- general surgeryThe branch of surgery that covers the main areas of surgical treatment. General surgeons treat diseases of...
- generalized anxiety disorderA condition marked by excessive worry and feelings of fear, dread, and uneasiness that last six months or...
- genericOfficial nonbrand names by which medicines are known. Generic names usually refer to the chemical name of the...
- geneticHaving to do with genes. Most genes are sequences of DNA that contain information for making specific RNA...
- genetic analysisA laboratory method that looks for changes in genes, gene expression, or chromosomes in a person’s cells or...
- genetic anticipationA phenomenon in which the signs and symptoms of some genetic conditions tend to become more severe and/or...
- genetic counselingA communication process between a specially trained health professional and a person concerned about the...
- genetic counselorA health professional who has special training in medical genetics and counseling. Genetic counselors help...
- genetic heterogeneityA term that describes when different gene mutations (changes) cause the same disease or condition. Genetic...
- genetic infantile agranulocytosisAn inherited disorder in which there is a lower-than-normal number of neutrophils (a type of white blood cell...
- genetic markerA specific sequence of DNA at a known location on a chromosome. There are many genetic markers on each...
- genetic marker of susceptibilityA specific change in a person’s DNA that makes the person more likely to develop certain diseases such as...
- genetic predispositionAn inherited increase in the risk of developing a disease. Also called genetic susceptibility, hereditary...
- genetic profileInformation about changes in specific genes, gene expression, or chromosomes in cells or tissue of a person...
- genetic screeningThe process of testing individuals in a given population to identify those who have an increased risk of...
- genetic susceptibilityAn inherited increase in the risk of developing a disease. Also called genetic predisposition, hereditary...
- genetic testingA laboratory method that looks for changes in genes, gene expression, or chromosomes in a person’s cells or...
- genetically modified interleukin-12 transgene-encoding Bifidobacterium longumA live, genetically modified probiotic bacteria Bifidobacterium longum (B. longum) engineered to deliver...
- genetically-modified anti-HER2-CAR-CD28zeta-expressing allogeneic NK-92/5.28.z cellsA preparation of genetically-modified natural killer (NK) cells derived from the allogeneic NK-92 cell line...
- genetically-modified MAGE-A3-expressing MG1 Maraba virus vaccineA vaccine consisting of the attenuated, genetically-modified, oncolytic form of the Maraba virus, MG1, which...
- geneticistA scientist who has special training in the study of genes and heredity (the passing of genetic information...
- geneticsThe study of genes and heredity. Heredity is the passing of genetic information and traits (such as eye color...
- genisteinAn isoflavone found in soy products. Soy isoflavones are being studied to see if they help prevent cancer.
- genitalRefers to the genitalia (external and internal sex organs and glands).
- genital wartA raised growth on the surface of the genitals or in or around the anus caused by infection with certain...
- genitourinary systemThe parts of the body that play a role in reproduction, getting rid of waste products in the form of urine...
- genodermatosisAn inherited syndrome that includes a dermatological (skin) phenotype.
- genolimzumabAn immunoglobulin G4 (IgG4) humanized monoclonal antibody directed against the negative immunoregulatory...
- genomeThe complete set of DNA (genetic material) in an organism. In people, almost every cell in the body contains...
- genome-wide association studyA study that compares DNA markers across the genome (the complete genetic material in a person) in people...
- genomic characterizationA laboratory method that uses a sample of tissue, blood, or other body fluid to learn about all the genes in...
- genomic imprintingAn epigenetic process resulting in the inactivation of an allele depending on which parent it was inherited...
- genomic instabilityThe increased tendency for DNA mutations (changes) and other genetic changes to occur during cell division...
- genomic profilingA laboratory method that uses a sample of tissue, blood, or other body fluid to learn about all the genes in...
- genomic sequencingA laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type...
- genomic testingA laboratory method that looks for genetic changes across all the DNA (including the entire set of genes) in...
- genomicsThe study of the complete set of DNA (including all of its genes) in a person or other organism. Almost every...
- genotypeA term that refers to the two alleles present at a specific locus in the genome. Genotype also refers to the...
- genotypingA laboratory process in which an individual’s germline DNA is analyzed for specific nucleotides or bases to...
- gentuximabA recombinant, humanized monoclonal antibody directed against the vascular endothelial growth factor receptor...
- GEP-NETA rare type of tumor that can form in the pancreas or in other parts of the gastrointestinal tract, including...
- geraniumA type of plant that is native to southern Africa and has white, pink, purple, or red flowers and 3- to...
- geranylgeranyltransferase I inhibitorA substance that inhibits protein geranylgeranyltransferase type 1 (GGTase-I), with potential antineoplastic...
- germA bacterium, virus, or other microorganism that can cause infection and disease.
- germ cellA cell that develops into a reproductive cell, which is an egg in females and a sperm in males.
- germ cell tumorA type of tumor that begins in the cells that give rise to sperm or eggs. Germ cell tumors can occur almost...
- German chamomileA plant whose daisy-like flowers are used in tea to calm and relax, improve sleep, and help stomach problems...
- German Commission EThe German Federal Institute for Drugs and Medical Devices Commission E. A committee made up of scientists...
- germfreeFree of bacteria, viruses, and other microorganisms that can cause infection and disease.
- germicideAny substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause...
- germinomaA type of tumor that begins in germ cells (cells that form sperm or eggs). Germinomas can occur in the...
- germlineThe cells that form eggs in females and sperm in males. Germline cells contain the genetic information that...
- germline DNAThe DNA in germ cells (egg and sperm cells that join to form an embryo). Germline DNA is the source of DNA...
- germline mosaicismA term that refers to the presence of a pathogenic variant that is confined to the ovaries or testes...
- germline mutationA gene change in a body's reproductive cell (egg or sperm) that becomes incorporated into the DNA of every...
- germline variantA gene change in a body's reproductive cell (egg or sperm) that becomes incorporated into the DNA of every...
- Gerota's capsuleA fibrous envelope of tissue that surrounds the kidney. Also called Gerota's fascia and renal fascia.
- Gerota's fasciaA fibrous envelope of tissue that surrounds the kidney. Also called Gerota's capsule and renal fascia.
- Gerson therapyA diet plan that has been claimed to be a treatment for cancer, migraine, tuberculosis, and other diseases...
- gestational carrierA woman who carries and gives birth to a baby for a person who is not able to have children. Eggs from an egg...
- gestational surrogateA woman who carries and gives birth to a baby for a person who is not able to have children. Eggs from an egg...
- gestational trophoblastic diseaseA rare condition in which abnormal cells grow inside the uterus from tissue that forms after conception (the...
- gestational trophoblastic tumorA rare condition in which abnormal cells grow inside the uterus from tissue that forms after conception (the...
- gevokizumabAn IgG2 humanized monoclonal antibody against the pro-inflammatory cytokine interleukin 1 beta (IL-1b) with...
- gFOBTA test that checks for occult (hidden) blood in the stool. Small samples of stool are placed on special cards...
- GG745A drug used to treat symptoms of an enlarged prostate gland. It is being studied in the treatment of male...
- ghrelin peptide analogueA ghrelin peptide analogue with potential anti-cachexia activity. Upon subcutaneous administration, ghrelin...
- GIHaving to do with the gastrointestinal (GI) tract or GI system. The GI tract includes the mouth, throat...
- GI14721An antitumor drug that belongs to the family of drugs called topoisomerase inhibitors. It is a camptothecin...
- GI-4000 vaccineA vaccine containing a heat-killed recombinant Saccharomyces cerevisiae yeast transfected with mutated forms...
- giant cell fibroblastomaA rare type of soft tissue tumor marked by painless nodules in the dermis (the inner layer of the two main...
- giant cell tumorA rare tumor that usually forms in bone, but may also form in cartilage, muscle, fat, blood vessels, or other...
- giant hypertrophic gastritisA condition marked by inflammation and ulcers (breaks on the skin or on the surface of an organ) of the...
- giant lymph node hyperplasiaA rare disorder in which benign (not cancer) growths form in lymph node tissue. There are two main ways that...
- gigantismA condition in which the whole body or any of its parts grow much larger than normal.
- GilotrifA drug used to treat certain types of non-small cell lung cancer that have spread to other parts of the body...
- gilteritinibAn orally bioavailable inhibitor of the receptor tyrosine kinases (RTKs) FMS-like tyrosine kinase 3 (FLT3...
- gilteritinib fumarateA drug used to treat adults with acute myeloid leukemia that came back or did not get better with other...
- gimatecanA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
- gimeracilA pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines...
- gingerAn herb with a root that has been used in cooking, and by some cultures to treat nausea, vomiting, and...
- ginger extractAn extract of the rhizome of the perennial plant Zingiber officinale with potential antineoplastic activity...
- gingivaThe tissue of the upper and lower jaws that surrounds the base of the teeth. Also called gums.
- ginkgoA tree native to China. Substances taken from the leaves and seeds have been used in some cultures to treat...
- ginkgo bilobaA tree native to China. Substances taken from the leaves and seeds have been used in some cultures to treat...
- ginsengAn herb with a root that has been used in some cultures to treat certain medical problems. It may have...
- ginseng compoundA compound containing the traditional Chinese medicine (TCM) ginseng, a herb belonging to the Araliaceae...
- ginseng/lingzhi mushroom/Cordyceps sinensis/rose oral liquidAn orally available supplement containing ginseng, lingzhi mushroom, Cordyceps sinensis, and rose with...
- ginsenoside Rg3 capsuleA capsule containing the steroidal saponin ginsenoside Rg3 isolated from the root of Panax ginseng, with...
- ginsenosides supplementAn oral and herbal supplement containing sixteen ginsenosides derived from ginseng and including the...
- GintemetostatAn orally available small molecule inhibitor of the histone-lysine N-methyltransferase nuclear...
- giredestrantAn orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic...
- girentuximabA chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal...
- GISTA type of tumor that usually begins in cells in the wall of the gastrointestinal tract. Some GISTs may grow...
- GITRL RNA-transfected autologous dendritic cell vaccineAn autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. GITRL...
- givinostatAn orally bioavailable hydroxymate inhibitor of histone deacetylase (HDAC) with potential anti-inflammatory...
- givosiranA proprietary enhanced stabilization chemistry (ESC)-stabilized conjugate composed of the liver-targeted...
- glandAn organ that makes one or more substances, such as hormones, digestive juices, sweat, tears, saliva, or...
- gland of LieberkuhnTube-like gland found in the lining of the colon and rectum. Glands of Lieberkuhn renew the lining of the...
- glandular cell of the cervixA type of cell that makes mucus and is found in tissue that lines the inner part of the cervix. Abnormal...
- glandular epitheliumA type of tissue that lines certain internal organs and makes and releases substances in the body, such as...
- glandular tissueA type of tissue that lines certain internal organs and makes and releases substances in the body, such as...
- glans penisThe rounded, gland-like head of the penis.
- glasdegib maleateA drug used with low-dose cytarabine to treat acute myeloid leukemia that is newly diagnosed. It is used in...
- glaucomaA condition in which there is a build-up of fluid in the eye, which presses on the retina and the optic...
- Gleason scoreA way of describing prostate cancer based on how abnormal the cancer cells in a biopsy sample look under a...
- glecaprevir/pibrentasvirA fixed dose combination of glecaprevir, an inhibitor of the hepatitis C virus (HCV) NS3/4A serine protease...
- glecirasibAn orally available inhibitor of the oncogenic KRAS substitution mutation, G12C, with potential...
- GleevecA drug used to treat certain types of leukemia and other blood cancers, gastrointestinal stromal tumors, skin...
- glembatumumab vedotinAn antibody-drug conjugate, consisting of the fully human monoclonal antibody CR011 directed against...
- GleolanA drug that contains the active ingredient aminolevulinic acid hydrochloride and is used during surgery to...
- GleostineA drug used to treat brain tumors that have already been treated with surgery or radiation therapy and...
- glesatinibAn orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic...
- Gliadel WaferA drug used with surgery and radiation therapy to treat high-grade glioma that has not already been treated...
- glial cellAny of the cells that hold nerve cells in place and help them work the way they should. The types of glial...
- glial tumorA group of tumors that form in glial cells in the brain and spinal cord. Glial cells support and protect the...
- gliclazideA short-acting, relatively high-potency, second-generation sulfonylurea compound with hypoglycemic activity...
- glimepirideA long-acting, third-generation sulfonylurea with hypoglycemic activity. Compared to other generations of...
- glioblastomaA fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain...
- glioblastoma cancer vaccine ERC1671A cancer vaccine composed of a combination of autologous glioblastoma (GBM) tumor cells, allogeneic GBM tumor...
- glioblastoma multiformeA fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain...
- glioblastoma multiforme multipeptide vaccine IMA950A cancer vaccine comprising 11 peptides associated with glioblastoma multiforme (GBM), with potential...
- gliomaA group of tumors that form in glial cells in the brain and spinal cord. Glial cells support and protect the...
- glioma lysate vaccine GBM6-ADAn allogeneic cell lysate-based vaccine derived from the glioma stem cell line GBM6-AD, which was isolated...
- glioma-associated antigen peptide-pulsed autologous dendritic cell vaccineA cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen...
- glioma-associated peptide-loaded dendritic cell vaccine SL-701A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various synthetic...
- glioneuronal tumorOne of a group of rare tumors that contain a mixture of nerve cells and glial cells (supporting cells) of the...
- gliosarcomaA type of glioma (cancer of the brain that comes from glial, or supportive, cells).
- glipizideA short-acting, second-generation sulfonylurea with hypoglycemic activity. Glipizide is rapidly absorbed, has...
- gliquidoneA potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation...
- glisoxepideA second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds...
- Globo H-DT vaccine OBI-833A carbohydrate-based vaccine comprised of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to...
- Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH conjugate vaccineA heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide...
- globulin component macrophage-activating factorA recombinant form of naturally-occurring GC (group-specific component) protein-derived macrophage-activating...
- glofitamabA drug used to treat adults with certain types of diffuse large B-cell lymphoma or large B-cell lymphoma that...
- glofitamab-gxbmA bispecific monoclonal antibody, with potential antineoplastic activity. Glofitamab contains two...
- glomerulonephritisA condition in which the tissues in the kidney become inflamed and have problems filtering waste from the...
- glossectomySurgical removal of all or part of the tongue.
- glottisThe middle part of the larynx; the area where the vocal cords are located.
- glucagonA hormone produced by the pancreas that increases the level of glucose (sugar) in the blood.
- glucagonomaA rare pancreatic tumor that produces a hormone called glucagon. Glucagonomas can produce symptoms similar to...
- glucarpidaseA drug used to treat toxic levels of the anticancer drug methotrexate in the blood of adults and children...
- glucocorticoidA compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect...
- glucocorticoid receptor antagonist ORIC-101A mifepristone-based steroidal glucocorticoid receptor (GR) antagonist with potential antineoplastic...
- gluconeogenesisThe process of making glucose (sugar) from its own breakdown products or from the breakdown products of...
- GlucophageA drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in...
- glucosamine sulfate/chondroitin sulfate tabletAn oral tablet formulation of a dietary supplement containing the sulfate salts of the amino sugar...
- glucoseA type of sugar; the chief source of energy for living organisms.
- glucose-6-phosphate dehydrogenase deficiencyAn inherited disorder in which a person doesn’t have enough of an enzyme called G6PD that helps red blood...
- glucuronic acidA form of a type of sugar called glucose that helps remove harmful substances from the body. Glucuronic acid...
- glufosfamideAn anticancer drug that belongs to the family of drugs called alkylating agents.
- glutamic acidOne of twenty amino acids (molecules that join together to form proteins). Glutamic acid may help nerve cells...
- glutaminase inhibitor CB-839 hydrochlorideThe hydrochloride salt form of CB-839, an orally bioavailable inhibitor of glutaminase, with potential...
- glutaminase-1 inhibitor IACS-6274An orally bioavailable inhibitor of the metabolic enzyme glutaminase-1 (GLS1), with potential antineoplastic...
- glutamineAn amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by...
- glutathioneA substance found in plant and animal tissues that has many functions in a cell. These include activating...
- glutathione disulfide NOV-002A stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin...
- glutathione pegylated liposomal doxorubicin hydrochloride formulation 2B3-101A glutathione (GSH) pegylated, liposome-encapsulated preparation of the hydrochloride salt form of the...
- glutathione S-transferaseA family of enzymes involved in metabolism and in making toxic compounds less harmful to the body.
- gluten-free compact nutritional supplement drinkA gluten-free, calorie-dense, milkshake-like nutritional supplement drink containing all essential vitamins...
- gluten-free DHA/EPA/GLA/antioxidant-rich nutritional liquidA gluten- and lactose-free, energy-rich, calorie-dense, non-complete liquid nutritional supplement enriched...
- gluten-free/fiber enriched compact nutritional supplement drinkA gluten-free, calorie-dense, fiber-enriched milkshake-like nutritional supplement drink containing all...
- glyburideA sulfonamide urea derivative with antihyperglycemic activity that can potentially be used to decrease...
- glycanA large carbohydrate molecule. It contains many small sugar molecules that are joined chemically. Also called...
- glycan analysisA study of the types of carbohydrate (sugar) molecules attached to proteins in cells. Proteins with...
- glycemiaGlucose (a type of sugar) found in the blood. Also called blood sugar.
- glycemic indexA measure of the increase in the level of blood glucose (a type of sugar) caused by eating a specific...
- glycerin enemaAn enema solution containing 5% glycerin, a trihydroxy alcohol with osmotic laxative activity. Upon rectal...
- glycinamide ribonucleotide formyltransferase inhibitorA drug that blocks DNA synthesis and may prevent tumor growth. It is being studied as a treatment for cancer.
- glycineA non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in...
- Glycine maxA product from a plant of Asian origin that produces beans used in many food products. Glycine max contains...
- glycocyamineA naturally-occurring derivative of glycine and a metabolic precursor of creatine. Glycocyamine, also known...
- glyco-engineered anti-CD20 monoclonal antibody CHO H01A glyco-engineered monoclonal antibody directed against the human B-cell-specific cell surface antigen CD20...
- glycogen storage diseaseA type of inherited disorder in which there are problems with how a form of glucose (sugar) called glycogen...
- glycolic acidA substance found in some fruits, sugar beets, and sugar cane. It is used in skin care products to reduce...
- glycolysisA process in which glucose (sugar) is partially broken down by cells in enzyme reactions that do not need...
- glycooptimized trastuzumab-GEXA glycoengineered form of a monoclonal antibody directed against the human epidermal growth factor receptor-2...
- glycopeptideA short chain of amino acids (the building blocks of proteins) that has sugar molecules attached to it. Some...
- glycopeptide antibioticOne of a class of antibiotics originally isolated from plant and soil bacteria with structures containing...
- glycoproteinA protein that has sugar molecules attached to it.
- glycoprotein 100gp100. A tumor-specific antigen used in the development of cancer vaccines. Also called gp100.
- glycopyrrolateA synthetic quaternary ammonium that is an anticholinergic agent with antispasmodic activity. Glycopyrrolate...
- glycosaminoglycanA type of long, unbranched polysaccharide molecule. Glycosaminoglycans are major structural components of...
- glycosylated recombinant human G-CSF AVI-014A glycosylated form of a recombinant agent that is chemically identical to or similar to endogenous human...
- glycosylated recombinant human interleukin-7A glycosylated recombinant protein which is chemically identical to or similar to endogenous human...
- glymidineA sulfapyrimidine derivative,also known as glycodiazine, with antihyperglycemic activity. Like sulfonylureas...
- GlyT2/5HT2a antagonist VVZ-149An antagonist of both glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with potential...
- GM2/GD2/GD3 lactone-KLH conjugate trivalent vaccineA trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the...
- GM2-KLH vaccineA substance used to stimulate the production of antibodies that fight certain cancer cells.
- GM.CD40L cell vaccineA cell-based vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage...
- GM-CSFA substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that...
- GM-CSF-encoding oncolytic adenovirus CGTG-102A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine...
- GM-CSF-secreting breast tumor vaccineA vaccine that is being studied as a way to help the body’s immune system kill breast cancer cells. To make...
- GM-CSF-secreting MVX-2-loaded capsules/autologous irradiated tumor cell vaccine MVX-ONCO-2A cancer vaccine composed of autologous irradiated tumor cells and two implantable capsules loaded with MVX-2...
- GM-K562 cell vaccineA cell-based vaccine comprised of K562 cells transfected with the granulocyte macrophage-colony stimulating...
- GNAQ/GNA11 antagonist DYP688An antagonist of guanine nucleotide-binding protein G(q) subunit alpha (GNAQ)/ guanine nucleotide-binding...
- GnRHA hormone made by a part of the brain called the hypothalamus. GnRH causes the pituitary gland in the brain...
- GnRH agonistA substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are...
- GnRH antagonistA substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH)...
- GnRH antagonist SHR7280An orally bioavailable gonadotropin-releasing hormone (GnRH) receptor antagonist, with potential hormone...
- GnRH antagonist VERU-100A long-acting depot formulation of a gonadotropin-releasing hormone (GnRH) receptor antagonist decapeptide...
- GnRHaA substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are...
- goiterAn enlarged thyroid. It may be caused by too little iodine in the diet or by other conditions. Most goiters...
- golcadomideA modulator of the E3 ubiquitin ligase complex containing cereblon (CRL4-CRBN E3 ubiquitin ligase), with...
- gold fiducial marker seedsTiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly...
- gold fiducial markersTiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly...
- gold seedsTiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly...
- gold sodium thiomalateThe sodium salt of gold thiomalic acid, an organogold compound with antirheumatic and potential...
- gold therapyA procedure that uses gold salts (a salt form of the metal element gold) to treat diseases, such as...
- goldenrodA group of North American weedy herbs belonging to the genus Solidago (family Asteraceae) with potential...
- gold-seed fiducial markersTiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly...
- Golgi apparatusA stack of small flat sacs formed by membranes inside the cell’s cytoplasm (gel-like fluid). The Golgi...
- Golgi bodyA stack of small flat sacs formed by membranes inside the cell’s cytoplasm (gel-like fluid). The Golgi body...
- Golgi complexA stack of small flat sacs formed by membranes inside the cell’s cytoplasm (gel-like fluid). The Golgi...
- golidocitinibAn orally available inhibitor of Janus-associated kinase 1 (JAK1), with potential antineoplastic activity...
- golimumabA human monoclonal antibody directed against the pro-inflammatory cytokine tumor necrosis factor-alpha...
- golnerminogene pradenovecA recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine...
- golotimodAn orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by...
- golvatinibAn orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2...
- gonadThe part of the reproductive system that produces and releases eggs (ovary) or sperm (testicle/testis).
- gonadal dysgenesisAbnormal development of a gonad (ovary or testicle). Men with gonadal dysgenesis have a greater risk of...
- gonadal mosaicismA term that refers to the presence of a pathogenic variant that is confined to the ovaries or testes. Gonadal...
- gonadal shieldingA procedure used to help keep a person fertile by preventing damage to reproductive organs during radiation...
- gonadoblastomaA rare tumor that is made up of more than one type of cell found in the gonads (testicles and ovaries)...
- gonadotrophin releasing hormone analogueA synthetic analog of the endogenous hormone gonadotropin-releasing hormone (GnRH), with potential...
- gonadotropin-releasing hormoneA hormone made by a part of the brain called the hypothalamus. Gonadotropin-releasing hormone causes the...
- gonadotropin-releasing hormone agonistA substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are...
- gonadotropin-releasing hormone antagonistA substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH)...
- gonioscopyA procedure in which a gonioscope (special lens) is used to look at the front part of the eye between the...
- Gonzalez regimenAn alternative therapy that is being studied as a treatment for pancreatic cancer. It includes a special...
- Good Clinical PracticeAn international set of guidelines that helps make sure that the results of a clinical trial are reliable and...
- gorilla-derived adenovirus-expressing HPV-16/18 E6/E7 vaccineAn off-the-shelf (OTS) cancer vaccine comprised of a genetically engineered, replication-deficient...
- gorilla-derived adenovirus-expressing HPV-6/11 vaccine PRGN-2012An off-the-shelf (OTS) cancer vaccine comprised of a genetically engineered, replication-deficient...
- Gorlin syndromeA rare, inherited disorder that affects many organs and tissues in the body. People with this disorder have a...
- goserelin acetateA drug used to treat prostate cancer, relieve the symptoms of advanced breast cancer, and treat problems with...
- goserelin acetate extended-release microspheres LY01005A long-acting, extended-release microsphere formulation of the acetate form of goserelin, a synthetic...
- goserelin acetate extended-release microspheres LY01022A long-acting, extended-release (ER) microsphere formulation of the acetate form of goserelin, a synthetic...
- gossypolAn orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from...
- gossypol acetic acidA substance being studied in the treatment of several types of cancer. It is a form of a chemical taken from...
- GotistobartA humanized, pH-sensitive immunoglobulin (Ig) G1 monoclonal antibody directed against the human...
- goutA condition marked by increased levels of uric acid in the blood, joints, and tissue. The buildup of uric...
- gozanertinibAn orally bioavailable dual kinase inhibitor of epidermal growth factor receptor (EGFR; ErbB1) and human...
- gozetotideAn unlabeled radiotracer composed of the human prostate specific membrane antigen (PSMA)-targeting ligand and...
- gp100A tumor-specific antigen used in the development of cancer vaccines. Also called glycoprotein 100.
- gp100 antigenA melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a...
- gp100:154-162 peptide vaccineA peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100...
- gp100:209-217(210M) peptide vaccineA synthetic peptide cancer vaccine consisting of amino acid residues 209 through 217 of the glycoprotein 100...
- gp100:280-288(288V) peptide vaccineA peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100...
- gp100-fowlpox vaccineA cancer vaccine comprised of a recombinant fowlpox virus vector encoding the melanoma antigen glycoprotein...
- GP2 peptide/GM-CSF vaccineA vaccine containing a HER2/Neu-derived epitope (amino acids 654-662) (GP2), and combined with...
- gp209-2MA peptide (short piece of protein) made from the tumor-specific antigen gp100, and used to make vaccines...
- gp96 heat shock protein-peptide complex vaccineA vaccine made from a patient’s tumor cells that may help the body’s immune system kill cancer cells. This...
- gp96 HSP-peptide complexA vaccine made from a patient’s tumor cells that may help the body’s immune system kill cancer cells. This...
- gp96-secreting allogeneic bladder cancer cell vaccine HS-410An allogeneic urothelial bladder cancer cell vaccine expressing a recombinant secretory form of the...
- GPC3-targeted plasmid DNA vaccine NWRD06A plasmid DNA therapeutic cancer vaccine encoding glypican-3 (GPC3), with potential immunomodulating and...
- GPI-0100A semi-synthetic triterpene glycoside, derived from the naturally occurring saponins. GPI-0100 functions as...
- GPR35 inhibitor CT3001An orally bioavailable inhibitor of G-protein coupled receptor 35 (GPR35) and formulated with polyethylene...
- GPRC5D/BCMA/CD3-targeting T-cell engager IBI3003A T-cell engager (TCE) targeting the tumor-associated antigens (TAAs) B-cell maturation antigen (BCMA; tumor...
- GPX-100An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline.
- G-quadruplex stabilizer BMVCA carbazole derivative (3,6-bis[2-(1-methylpyridinium)vinyl]carbazole diiodide) that selectively targets to...
- gradeIn cancer, a description of a tumor based on how abnormal the cancer cells and tissue look under a microscope...
- grade 1 follicular lymphomaAn indolent (slow-growing) type of non-Hodgkin lymphoma marked by enlarged lymph nodes and small cells that...
- grade 2 follicular lymphomaAn indolent (slow-growing) type of non-Hodgkin lymphoma marked by enlarged lymph nodes and a mix of large...
- grade 3 follicular lymphomaA type of non-Hodgkin lymphoma marked by large cells and enlarged lymph nodes. Grade 3 follicular lymphoma is...
- Grade GroupA way of describing prostate cancer based on how abnormal the cancer cells in a biopsy sample look under a...
- grade I DCISA condition in which cells that look mostly like normal cells under a microscope are found in the lining of a...
- grade I ductal carcinoma in situA condition in which cells that look mostly like normal cells under a microscope are found in the lining of a...
582 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.