Girentuximab
Term · Oncology and biomedicine · MLC-T-ONC-013948
A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, girentuximab may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents.
| Identifier | MLC-T-ONC-013948 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | MOAB G250 |
| Synonyms | WX-G250; monoclonal antibody G-250; chimeric monoclonal antibody cG250 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013948",
"term": "Girentuximab",
"field": "Oncology and biomedicine",
"definition": "A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, girentuximab may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents.",
"abbreviation": "MOAB G250",
"synonyms": [
"WX-G250",
"monoclonal antibody G-250",
"chimeric monoclonal antibody cG250"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/girentuximab/"
}
Record 7,989 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.