indium In 111-DOTA-girentuximab

{
  "id": "MLC-T-ONC-014432",
  "term": "indium In 111-DOTA-girentuximab",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate comprised of the chimeric monoclonal antibody girentuximab conjugated with the gamma-emitting radioisotope indium In 111. Indium In 111-DOTA-girentuximab binds to G250, allowing the localization of G250-expressing tumor cells using gamma scintigraphy. Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA).",
  "synonyms": [
    "111-indium labeled chimeric monoclonal antibody G250",
    "indium In 111 chimeric monoclonal antibody G250"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-dota-girentuximab/"
}