indium In 111 monoclonal antibody huPAM4

{
  "id": "MLC-T-ONC-014419",
  "term": "indium In 111 monoclonal antibody huPAM4",
  "field": "Oncology and biomedicine",
  "definition": "The humanized monoclonal antibody huPAM4, directed against the pancreatic cancer antigen MUC-1 and radiolabled with the gamma-emitting radioisotope indium I 111, with radioisotopic and antibody activities. Upon administration, indium In 111 monoclonal antibody huPAM4 may bind to MUC-1-positive tumor cells, allowing radioimmunolocalization with gamma scintigraphy. Overexpressed by many tumor cell types, MUC-1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein.",
  "synonyms": [
    "111 In- labeled humanized PAM4 IgG"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-monoclonal-antibody-hupam4/"
}