indium In 111 chimeric monoclonal antibody 806

{
  "id": "MLC-T-ONC-014413",
  "term": "indium In 111 chimeric monoclonal antibody 806",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant chimeric, mouse-human monoclonal antibody IgG1, directed against the epidermal growth factor receptor (EGFR) and labeled with the radioisotope indium-111, with potential radioimaging activity. Indium 111 chimeric monoclonal antibody 806 binds to a specific epitope on EGFR-expressing tumor cells, allowing imaging of EGFR-expressing tumor cells using gamma scintigraphy. EGFR is a receptor tyrosine kinase that is involved in the regulation of cell growth and is found to be overexpressed on the cell surfaces of many tumor cell types.",
  "abbreviation": "111-Indium-ch806",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-chimeric-monoclonal-antibody-806/"
}