indium In 111 FPI-2058

{
  "id": "MLC-T-ONC-014414",
  "term": "indium In 111 FPI-2058",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate consisting of the neurotensin receptor type 1 (NTR1; NTSR1) antagonist, IPN01087 (3BP-227) that is linked to the radioisotope indium In 111, with potential imaging activity during single photon emission computed tomography (SPECT)/computed tomography (PET/CT). Upon administration, indium In 111 IPN01087 targets and binds to NTR1 expressed on certain tumor cells. Upon binding and radioimaging, NTR1-expressing tumor cells can be visualized and the biodistribution of IPN01087 can be assessed. NTR1, a G-protein coupled receptor, is highly expressed in ductal pancreatic adenocarcinoma but not in normal pancreatic tissue.",
  "synonyms": [
    "111In-IPN01087",
    "111indium-labeled IPN01087",
    "(111In)-IPN01087",
    "indium In 111 3BP-227",
    "111 In-3BP-227",
    "[111In]-FPI-2058",
    "indium In 111 IPN01087"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/indium-in-111-fpi-2058/"
}