Ga-68-labeled F(ab') 2- trastuzumab

{
  "id": "MLC-T-ONC-013802",
  "term": "Ga-68-labeled F(ab') 2- trastuzumab",
  "field": "Oncology and biomedicine",
  "definition": "A radioimmunoconjugate consisting of a trastuzumab fragment labeled with the positron-emitting radioisotope gallium Ga 68 with radioisotopic and antibody activities. Upon administration, Ga-68-labeled F(ab')2-trastuzumab may bind to HER2-positive tumor cells, allowing radioimmunolocalization with positron emission tomography (PET). Trastuzumab is a recombinant humanized monoclonal antibody that selectively binds to the extracellular domain of human epidermal growth factor receptor 2 (HER2), overexpressed by many adenocarcinomas, particularly breast adenocarcinomas.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ga-68-labeled-f-ab-2-trastuzumab/"
}