gallium Ga 68 R8760

{
  "id": "MLC-T-ONC-013833",
  "term": "gallium Ga 68 R8760",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of a melanocortin 2 receptor (MC2R; adrenocorticotropic hormone receptor; ACTHR)-binding ligand, conjugated to the radioisotope gallium Ga 68, with potential use as a tracer for MC2R-expressing tumors during positron emission tomography (PET). Upon administration of gallium Ga 68 R8760, the MC2R-targeting moiety targets and binds to MC2R-expressing tumor cells. Upon binding, MC2R-expressing tumor cells can be detected during PET imaging. MC2R, a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors, plays a key role in adrenal steroidogenesis and is overexpressed in adrenocortical carcinoma.",
  "synonyms": [
    "68Ga-R8760",
    "gallium Ga 68-R8760"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-r8760/"
}