Gallium Ga 68 P3

{
  "id": "MLC-T-ONC-013832",
  "term": "Gallium Ga 68 P3",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting ligand, P3, labeled with the radioisotope gallium Ga 68, with potential use as a tracer for PSMA-expressing tumors during positron emission tomography (PET). Upon intravenous administration of gallium Ga 68 P3, the P3 moiety targets and binds to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells as well as a variety of other solid tumors.",
  "synonyms": [
    "ERK inhibitor D3S-002",
    "68Ga-P3",
    "[68Ga]-P3",
    "[68Ga]P3"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-p3/"
}