Gallium Ga 68-EVS459

{
  "id": "MLC-T-ONC-013846",
  "term": "Gallium Ga 68-EVS459",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of EVS459, a folate receptor alpha (FRa; FolRa; FOLR1)-targeting moiety, radiolabeled with gallium Ga 68 (68Ga), with potential imaging activity upon positron emission tomography/computed tomography (PET/CT) or PET/magnetic resonance imaging (MRI). Upon administration of gallium Ga 68-EVS459, the FOLR1-targeting moiety targets and binds to FOLR1 expressed on tumor cells. Upon PET/CT or PET/MRI imaging, FOLR1-expressing tumor cells can be visualized. FOLR1 is a glycosylphosphatidylinositol linked cell-surface glycoprotein that is widely expressed in certain cancers while its expression is limited in normal tissues.",
  "synonyms": [
    "68Ga-EVS459",
    "[68Ga]-EVS459",
    "[68Ga]Ga-EVS459",
    "gallium Ga 68 EVS459",
    "gallium Ga 68-EVS-459"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-evs459/"
}