gallium Ga 68 N188

{
  "id": "MLC-T-ONC-013828",
  "term": "gallium Ga 68 N188",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of a nectin-4 (poliovirus receptor-like 4; PVRL4)-targeting moiety, labeled with gallium Ga 68, with potential nectin-4 imaging activity during positron emission topography (PET)/computed tomography (CT). After intravenous administration of gallium Ga 68 N188, the nectin-4-targeting moiety selectively targets and binds to nectin-4 expressed on tumor cells. Upon PET/CT imaging, nectin-4-expressing tumor cells can be visualized. Nectin-4, a tumor-associated antigen (TAA) belonging to the nectin family, is overexpressed in a variety of cancers, but has a restricted distribution in normal tissue.",
  "synonyms": [
    "[68Ga]N188",
    "gallium Ga 68-N188",
    "68Ga-N188"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-n188/"
}