gallium Ga 68-ICAM-1pep

{
  "id": "MLC-T-ONC-013849",
  "term": "gallium Ga 68-ICAM-1pep",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of ICAM-1pep, an intercellular adhesion molecule-1 (ICAM-1; CD54)-targeted tracer, labeled with the radioisotope gallium Ga 68, with potential use as a tracer for ICAM-1 during positron emission tomography/computed tomography (PET/CT). Upon administration of gallium Ga 68-ICAM-1pep, the ICAM-1pep moiety targets and binds to ICAM-1. Upon binding, ICAM-1pep expression can be detected during PET/CT imaging. ICAM-1, an inducible glycoprotein of the immunoglobulin superfamily (IgSF) normally expressed on leukocytes and endothelial cells, may be overexpressed in a variety of cancers. Its expression may also be up-regulated in nonirradiated tumors that are responsive to radiation therapy.",
  "synonyms": [
    "68Ga-ICAM-1pep",
    "68Ga-CD54pep",
    "gallium Ga 68-CD54pep"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-icam-1pep/"
}