gallium Ga 68 FAP-CHX

{
  "id": "MLC-T-ONC-013823",
  "term": "gallium Ga 68 FAP-CHX",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of FAP-CHX, a fibroblast activation protein (FAP)-targeted tracer, labeled with the radioisotope gallium Ga 68, with potential use as a tracer for FAP-expressing cancer-associated fibroblasts (CAFs) during positron emission tomography/computed tomography (PET/CT). Upon administration of gallium Ga 68 FAP-CHX, the FAP-CHX moiety targets and binds to FAP-expressing CAFs. Upon binding, FAP-expressing cells can be detected during PET/CT imaging. FAP, a cell surface protein, is overexpressed on CAFs in the tumor microenvironment (TME).",
  "synonyms": [
    "68Ga-FAP-CHX",
    "gallium Ga 68-FAP-CHX"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-fap-chx/"
}