Gallium Ga 68 FAPi-46

{
  "id": "MLC-T-ONC-013824",
  "term": "Gallium Ga 68 FAPi-46",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of FAPi-46, a quinoline-based fibroblast activation protein (FAP)-targeted tracer belonging to the group of FAP inhibitors (FAPi), conjugated to the radioisotope gallium Ga 68, with potential use as a tracer for FAP-expressing tumors during positron emission tomography (PET). Upon administration of gallium Ga 68 FAPi-46, the FAPi-46 moiety targets and binds to FAP-expressing tumor cells. Upon binding, FAP-expressing tumor cells can be detected during PET imaging. FAP, a cell surface protein, is overexpressed in a wide variety of cancer cell types.",
  "synonyms": [
    "68Ga-FAPi-46",
    "gallium-68-FAPi-46"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-fapi-46/"
}