MLchartDataset catalogue

Gallium Ga 68-labeled MLN6907

Term · Oncology and biomedicine · MLC-T-ONC-013855

A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography (PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic neurons in the brain, that is also overexpressed on the surface of a variety of cancer cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.

Table 1. Record
IdentifierMLC-T-ONC-013855
FieldOncology and biomedicine
Abbreviation[68Ga]MLN6907
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013855",
  "term": "Gallium Ga 68-labeled MLN6907",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography (PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic neurons in the brain, that is also overexpressed on the surface of a variety of cancer cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.",
  "abbreviation": "[68Ga]MLN6907",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-labeled-mln6907/"
}

Record 7,734 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.