Gallium Ga 68-labeled MLN6907
Term · Oncology and biomedicine · MLC-T-ONC-013855
A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography (PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic neurons in the brain, that is also overexpressed on the surface of a variety of cancer cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.
| Identifier | MLC-T-ONC-013855 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | [68Ga]MLN6907 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013855",
"term": "Gallium Ga 68-labeled MLN6907",
"field": "Oncology and biomedicine",
"definition": "A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography (PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic neurons in the brain, that is also overexpressed on the surface of a variety of cancer cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.",
"abbreviation": "[68Ga]MLN6907",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/gallium-ga-68-labeled-mln6907/"
}
Record 7,734 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.