gallium Ga 68-labeled NODAGA-MJ9
Term · Oncology and biomedicine · MLC-T-ONC-013856
A radiopharmaceutical agent comprised of a peptide targeting the gastrin releasing peptide receptor (GRPR) chelated with 1,4,7-triazacyclononane,1-glutaric acid-4,7 acetic acid (NODAGA) and radiolabeled with gallium Ga 68, with potential tumor imaging activity upon positron emission tomography (PET). After administration of gallium Ga 68-labeled-NODAGA-MJ9, the MJ9 moiety binds to GRPR located on tumor cells. Upon PET imaging, GRPR-expressing tumor cells can be visualized and expression levels can be quantified. GRPR is overexpressed on certain tumor cells and plays a key role in tumor proliferation and survival.
| Identifier | MLC-T-ONC-013856 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | Ga-68-NODAGA-MJ9 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013856",
"term": "gallium Ga 68-labeled NODAGA-MJ9",
"field": "Oncology and biomedicine",
"definition": "A radiopharmaceutical agent comprised of a peptide targeting the gastrin releasing peptide receptor (GRPR) chelated with 1,4,7-triazacyclononane,1-glutaric acid-4,7 acetic acid (NODAGA) and radiolabeled with gallium Ga 68, with potential tumor imaging activity upon positron emission tomography (PET). After administration of gallium Ga 68-labeled-NODAGA-MJ9, the MJ9 moiety binds to GRPR located on tumor cells. Upon PET imaging, GRPR-expressing tumor cells can be visualized and expression levels can be quantified. GRPR is overexpressed on certain tumor cells and plays a key role in tumor proliferation and survival.",
"synonyms": [
"Ga-68-NODAGA-MJ9"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/gallium-ga-68-labeled-nodaga-mj9/"
}
Record 7,736 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.