Gallium Ga 68-NeoB

{
  "id": "MLC-T-ONC-013860",
  "term": "Gallium Ga 68-NeoB",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate consisting of a gastrin-releasing peptide receptor (GRPR) antagonist linked via the chelating agent, dodecanetetraacetic acid (DOTA), to the beta-emitting radioisotope gallium Ga 68, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT). Upon administration, gallium Ga 68-NeoB binds to GRPRs present on cancer cells. Upon binding, this radioconjugate can be used to quantify tumor uptake of NeoBOMB1 using PET/CT. GRPR, also known as bombesin receptor subtype 2, is a G protein-coupled receptor that is overexpressed in some cancer types.",
  "synonyms": [
    "68Ga-DOTA-NeoBOMB1",
    "gallium-68 DOTA-NeoBOMB1",
    "68Ga-NeoB",
    "[68Ga]-NeoB",
    "gallium Ga 68 NeoBOMB1"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-neob/"
}