Gallium Ga 68-PSMA-R2

{
  "id": "MLC-T-ONC-013884",
  "term": "Gallium Ga 68-PSMA-R2",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of PSMA-R2, a human prostate-specific membrane antigen (PSMA)-targeting ligand, conjugated to the beta-emitting radioisotope gallium Ga 68, with potential imaging activity during positron emission topography/computed tomography (PET/CT). Upon administration of gallium Ga 68-PSMA-R2, the PSMA-R2 moiety targets and binds to PSMA-expressing tumor cells. This allows for visualization of PSMA-expressing cells upon imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on the majority of prostate tumor cells.",
  "synonyms": [
    "gallium Ga 68 PSMA-R2",
    "68GaPSMA-R2",
    "68Ga-PSMA-R2",
    "gallium-68 PSMA-R2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-psma-r2/"
}