MLchartDataset catalogue

gimeracil

Term · Oncology and biomedicine · MLC-T-ONC-013940

A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines.

Table 1. Record
IdentifierMLC-T-ONC-013940
FieldOncology and biomedicine
AbbreviationCDHP
Synonymschlorodihydroxypyridine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-013940",
  "term": "gimeracil",
  "field": "Oncology and biomedicine",
  "definition": "A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines.",
  "abbreviation": "CDHP",
  "synonyms": [
    "chlorodihydroxypyridine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gimeracil/"
}

Record 7,977 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.