MLchartDataset catalogue

aminothiadiazole

Term · Oncology and biomedicine · MLC-T-ONC-010034

A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist.

Table 1. Record
IdentifierMLC-T-ONC-010034
FieldOncology and biomedicine
AbbreviationA-TD
Synonyms2-Aminothiadiazole; Amino 134-Thiadiazole
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-010034",
  "term": "aminothiadiazole",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist.",
  "abbreviation": "A-TD",
  "synonyms": [
    "2-Aminothiadiazole",
    "Amino 134-Thiadiazole"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/aminothiadiazole/"
}

Record 982 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.