Inosine dialdehyde

{
  "id": "MLC-T-ONC-014462",
  "term": "Inosine dialdehyde",
  "field": "Oncology and biomedicine",
  "definition": "A toxic purine analogue. Inosine dialdehyde inhibits ribonucleotide reductase, resulting in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle arrest. This agent also forms stable covalent crosslinks in proteins, thereby inhibiting the activity of enzymes involved in nucleic acid synthesis.",
  "abbreviation": "IdA",
  "synonyms": [
    "INOX",
    "diglycoaldehyde"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/inosine-dialdehyde/"
}