glioma lysate vaccine GBM6-AD

{
  "id": "MLC-T-ONC-013960",
  "term": "glioma lysate vaccine GBM6-AD",
  "field": "Oncology and biomedicine",
  "definition": "An allogeneic cell lysate-based vaccine derived from the glioma stem cell line GBM6-AD, which was isolated from the brain tumor of a patient diagnosed with glioblastoma multiforme (GBM), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration, the glioma lysate vaccine GBM6-AD exposes the immune system to an undefined amount of glioma-associated antigens (GAAs), and stimulates the immune system to mount a specific anti-tumoral, cytotoxic T-lymphocyte (CTL)-mediated response against the GAA-expressing cells, resulting in glioma cell lysis.",
  "synonyms": [
    "GBM6-AD lysate protein vaccine",
    "glioma cell lysate vaccine GBM6-AD"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/glioma-lysate-vaccine-gbm6-ad/"
}