MLchartDataset catalogue

glioma-associated peptide-loaded dendritic cell vaccine SL-701

Term · Oncology and biomedicine · MLC-T-ONC-013962

A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis.

Table 1. Record
IdentifierMLC-T-ONC-013962
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013962",
  "term": "glioma-associated peptide-loaded dendritic cell vaccine SL-701",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/glioma-associated-peptide-loaded-dendritic-cell-vaccine-sl-701/"
}

Record 8,023 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.