Autologous tumor-specific antigen-loaded dendritic cells

{
  "id": "MLC-T-ONC-011809",
  "term": "Autologous tumor-specific antigen-loaded dendritic cells",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) loaded with tumor-specific antigen(s) (TSAs), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous TSA-loaded DCs, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the tumor cells expressing the TSA(s), resulting in tumor cell lysis.",
  "synonyms": [
    "autologous TSA-loaded dendritic cells",
    "autologous TSA-DCs",
    "autologous TSA-DC vaccine",
    "tumor specific antigen-loaded autologous dendritic cells",
    "autologous TSA-DC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-tumor-specific-antigen-loaded-dendritic-cells/"
}