Total tumor RNA-loaded dendritic cell vaccine

{
  "id": "MLC-T-ONC-017278",
  "term": "Total tumor RNA-loaded dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine containing autologous dendritic cells (DCs) that are loaded with total tumor RNA (TTRNA) from a specific tumor, with potential immunostimulatory and antineoplastic activities. Upon administration, TTRNA-loaded DC vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against the tumor-associated antigens (TAAs) encoded by the TTRNA.",
  "synonyms": [
    "TTRNA-loaded DC vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/total-tumor-rna-loaded-dendritic-cell-vaccine/"
}