autologous TAAs-loaded autologous dendritic cells AV-GBM-1

{
  "id": "MLC-T-ONC-011768",
  "term": "autologous TAAs-loaded autologous dendritic cells AV-GBM-1",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous dendritic cells (DCs) loaded with immunogenic tumor-associated antigens (TAAs) derived from cultured autologous glioblastoma multiforme (GBM) tumor cells, with potential immunostimulatory and antineoplastic activities. Upon administration, the autologous TAA-loaded DCs AV-GBM-1 expose the immune system to the GBM neoantigens, which results in a cytotoxic T-lymphocyte (CTL)-mediated immune response against the autologous GBM cells leading to GBM cell lysis.",
  "synonyms": [
    "neoantigen-loaded autologous dendritic cells AV-GBM-1",
    "autologous TAAs-loaded autologous DCs AV-GBM-1",
    "autologous dendritic cells loaded with autologous tumor associated antigens"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-taas-loaded-autologous-dendritic-cells-av-gbm-1/"
}