MLchartDataset catalogue

gallium Ga 68 satoreotide trizoxetan

Term · Oncology and biomedicine · MLC-T-ONC-013835

A radioconjugate consisting of the somatostatin antagonistic peptide OPS202 that is labeled with the positron-emitting radionuclide gallium Ga 68, which may be used as a somatostatin receptor (SSTR) imaging agent in conjunction with positron emission tomography (PET) to image neuroendocrine tumors (NETs). Gallium Ga 68 satoreotide trizoxetan binds to SSTR subtype 2 present on the cell membranes of many types of NETs. This allows for visualization of SSTR-positive cells upon imaging. SSTR subtypes have been shown to be present in large numbers on NETs and their metastases, while most other normal tissues express low levels of SSTR subtypes.

Table 1. Record
IdentifierMLC-T-ONC-013835
FieldOncology and biomedicine
Synonymsgallium Ga 68 OPS202; 68Ga-OPS202; 68Ga-NODAGA-JR11; gallium Ga 68 NODAGA-JR11
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013835",
  "term": "gallium Ga 68 satoreotide trizoxetan",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate consisting of the somatostatin antagonistic peptide OPS202 that is labeled with the positron-emitting radionuclide gallium Ga 68, which may be used as a somatostatin receptor (SSTR) imaging agent in conjunction with positron emission tomography (PET) to image neuroendocrine tumors (NETs). Gallium Ga 68 satoreotide trizoxetan binds to SSTR subtype 2 present on the cell membranes of many types of NETs. This allows for visualization of SSTR-positive cells upon imaging. SSTR subtypes have been shown to be present in large numbers on NETs and their metastases, while most other normal tissues express low levels of SSTR subtypes.",
  "synonyms": [
    "gallium Ga 68 OPS202",
    "68Ga-OPS202",
    "68Ga-NODAGA-JR11",
    "gallium Ga 68 NODAGA-JR11"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/gallium-ga-68-satoreotide-trizoxetan/"
}

Record 7,715 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.