Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: M (1,028)

Page 1 of 3

• M proteinAn antibody found in unusually large amounts in the blood or urine of people with multiple myeloma and other...
• M200A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies...
• M87o-transduced CD34+ peripheral blood stem cellsPeripheral blood stem cells (PBSCs) transduced with the retroviral vector M87o encoding for the HIV-1-entry...
• Ma huangA shrub native to China and India. The stems and roots are used in traditional medicine as a diuretic and for...
• Ma zi ren wanA proprietary, traditional Chinese herbal (TCH) formula composed of six different herbs: Semen Cannabis...
• Maackia amurensis seed lectinA preparation of lectin extracted from the seeds of Maackia amurensis, with potential antineoplastic...
• Machine learningA field of computer science that develops the processes by which computers are taught how to learn and...
• MacimorelinAn orally available synthetic mimetic of the growth hormone (GH) secretagogue ghrelin with potential...
• MacitentanAn orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and...
• Macrobiotic dietA plant-based diet that is high in unprocessed carbohydrates and low in fat and processed carbohydrates. A...
• MacrocalcificationA small deposit of calcium in the breast that cannot be felt but can be seen on a mammogram. It is usually...
• Macrocycle-bridged STING agonist E7766An agonist of macrocycle-bridged stimulator of interferon genes (STING) protein, with potential...
• MacroglobulinemiaA condition in which the blood contains high levels of large proteins and is too thick to flow through small...
• Macrogol 3350-based oral osmotic laxativeAn isotonic solution containing macrogol 3350 and electrolytes with laxative activity. Macrogol 3350-based...
• MacrophageA type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the...
• Macular degenerationA condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive...
• Macular edemaA buildup of fluid in the macula, the part of the retina (the light-sensitive layers of tissue at the back of...
• Maekmoondong-tangA traditional East Asian herbal medicine composed of six herbs, including Ophiopogonis tuber, Pinelliae...
• Maffucci syndromeA very rare disorder that affects the skin and cartilage. It is marked by benign (not cancer) growths of...
• MafosfamideA form of cyclophosphamide that can be administered as an intrathecal infusion. Mafosfamide is being studied...
• MAGE-10.A2A synthetic nonapeptide derived from a melanoma-associated antigen. Vaccination with MAGE-10.A2 may stimulate...
• MAGE-12 peptide vaccineA synthetic vaccine comprised of a peptide consisting of peptide fragments of melanoma-associated antigen 12...
• MAGE-3 antigenA protein found in many types of tumors but not in most normal tissues. Vaccines using pieces of the MAGE-3...
• MAGE-3.A1 peptide vaccineA synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived...
• MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccineA cancer vaccine containing multiple synthetic antigen peptides derived from MAGE-A1, Her-2/neu, and folate...
• MAGE-A1, MAGE-A3, NY-ESO-1 peptides vaccineA cancer vaccine comprised of synthetic peptides derived from human melanoma antigen A1 (MAGE-A1), human...
• MAGE-A1-specific T-cell receptor-transduced autologous T cellsA preparation of autologous CD4- and CD8-positive T lymphocytes genetically modified to express a T-cell...
• MAGE-A3 reactive T cell receptor-transduced autologous T cellsHuman autologous T-lymphocytes transduced with a retroviral vector encoding a T cell receptor (TCR) specific...
• MAGE-A3/12-specific TCR gene-transduced autologous PBLsHuman autologous peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T-cell...
• MAGE-A3-expressing adenovirus type5 vaccineAn oncolytic adenoviral vaccine composed of a replication-defective, E1- and E3-deleted adenovirus serotype 5...
• MAGE-A3/HPV 16 peptide vaccineA multi-epitope "Trojan antigen" ("TA") construct vaccine consisting of human melanoma antigen A3 (MAGE-A3)...
• MAGE-A4-specific T-cell engager CDR404A bispecific T-cell engaging antibody directed against the human leukocyte antigen (HLA)-A2-restricted...
• MAGE-A4-specific TCR gene-transduced T lymphocytes TBI-1201Autologous human T lymphocytes transduced with a retroviral vector encoding a T-cell receptor (TCR) specific...
• MagnesiumIn medicine, a mineral used by the body to help maintain muscles, nerves, and bones. It is also used in...
• Magnesium chloride-based lotionA skin lotion containing magnesium chloride and other trace minerals, that may be used for supplemental...
• Magnesium citrateThe citrate salt of the element magnesium with cathartic activity. The cathartic action of magnesium cations...
• Magnesium glycinateAn orally available magnesium salt of glycine. Magnesium activates over 600 enzymes and is essential for DNA...
• Magnesium hydroxideA solution of magnesium hydroxide with antacid and laxative properties. Milk of magnesium exerts its antacid...
• Magnesium isoglycyrrhizinateThe magnesium salt form of the saponin, isoglycyrrhizinate, a derivative of glycyrrhizic acid extracted from...
• Magnesium L-threonateA nutritional supplement containing the L-threonate form of magnesium (Mg) that can be used to normalize Mg...
• Magnesium oxideThe oxide salt of magnesium with antacid, laxative and vascular smooth muscle relaxant activities. Magnesium...
• Magnesium sulfateA drug used to treat pre-eclampsia and eclampsia (serious complications of pregnancy). Magnesium sulfate is...
• Magnesium valproateThe magnesium salt of valproic acid (2-propylpentanoic acid) with antiepileptic and potential antineoplastic...
• Magnesium-based bone void fillerAn injectable magnesium oxide-based bone void filler (BVF) with potential osteoconductive properties. Upon...
• Magnesium-rich mineral waterCarbonated, iron-depleted mineral water from the French springs of Beauregard-Vendon (Rouzat) containing very...
• Magnetic resonance angiographyA procedure that uses radio waves and a powerful magnet linked to a computer to create detailed pictures of...
• Magnetic resonance cholangiopancreatographyA procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of the...
• Magnetic resonance imagingA procedure that uses radio waves, a powerful magnet, and a computer to make a series of detailed pictures of...
• Magnetic resonance lymphangiographyA procedure that uses radio waves, a powerful magnet, and a computer to make a series of detailed pictures of...
• Magnetic resonance perfusion imagingA special type of magnetic resonance imaging (MRI) that uses an injected dye in order to see blood flow...
• Magnetic resonance spectroscopic imagingA noninvasive imaging method that provides information about cellular activity (metabolic information). It is...
• Magnetic-targeted carrierA tiny bead made from particles of iron and carbon that can be attached to an anticancer drug. A magnet...
• MagnevistA substance used in magnetic resonance imaging (MRI) to help make clear pictures of the brain, spine, heart...
• MagrolimabA humanized monoclonal antibody targeting the human cell surface antigen CD47, with potential...
• MAG-Tn3/AS15 vaccineA vaccine containing synthetic multiple antigenic glycopeptide (MAG) composed of tri Tn glycotope (MAG-Tn3)...
• Mai dongThe root of the perennial herbaceous plant Ophiopogon belonging to the Liliaceae family. Mai Dong is believed...
• Maidenhair treeA tree native to China. Substances taken from the leaves and seeds have been used in some cultures to treat...
• Mainstream medicineA system in which medical doctors and other health care professionals (such as nurses, pharmacists, and...
• Mainstream smokeTobacco smoke that is exhaled by smokers. Mainstream smoke can be a form of secondhand smoke. It contains...
• Maintenance therapyTreatment that is given to help keep cancer from coming back after it has disappeared following the initial...
• Maitake mushroom extractAn extract of the edible mushroom Maitaki, Grifola frondosa, rich in glucan polysaccharides, with potential...
• Malabsorption syndromeA group of symptoms such as gas, bloating, abdominal pain, and diarrhea resulting from the body's inability...
• Male breast cancerCancer that forms in tissues of the breast in men. Most male breast cancer begins in cells lining the ducts...
• MalignancyA term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant...
• MalignantA term used to describe cancer. Malignant cells grow in an uncontrolled way and can invade nearby tissues and...
• Malignant ascitesA condition in which fluid containing cancer cells collects in the abdomen.
• Malignant ectomesenchymomaA rare, fast-growing tumor of the nervous system or soft tissue that occurs in children and young adults...
• Malignant fibrous cytomaA type of cancer that usually forms in the soft tissue, but it may also form in bone. It can occur anywhere...
• Malignant fibrous histiocytomaA type of cancer that usually forms in the soft tissue, but it may also form in bone. It can occur anywhere...
• Malignant glioma tumor lysate-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from malignant...
• Malignant meningiomaA rare, fast-growing tumor that forms in one of the inner layers of the meninges (thin layers of tissue that...
• Malignant mesotheliomaA rare type of cancer in which malignant cells are found in the lining of the chest or abdomen. Exposure to...
• Malignant mixed Müllerian tumorA rare type of tumor that is a mixture of carcinoma and sarcoma cells. MMMT usually occurs in the uterus...
• Malignant pericardial effusionA condition in which cancer causes extra fluid to collect inside the sac around the heart. The extra fluid...
• Malignant peripheral nerve sheath tumorA type of soft tissue sarcoma that develops in cells that form a protective sheath (covering) around...
• Malignant peritoneal effusionA condition in which cancer causes extra fluid to collect between the thin layers of the peritoneum (tissue...
• Malignant pleural effusionA condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue...
• Malignant triton tumorA very rare, fast-growing type of cancer that forms in the nerve sheath (a protective covering around nerves...
• MalnourishedDescribes a condition caused by not getting enough calories or the right amount of key nutrients needed for...
• MalnutritionA condition caused by not getting enough calories or the right amount of key nutrients, such as vitamins and...
• MalondialdehydeA byproduct of lipid (fat) metabolism in the body. It is also found in many foods and can be present in high...
• MALT lymphomaA type of cancer that arises in cells in mucosal tissue that are involved in antibody production. Also called...
• MALT1 inhibitor ABBV-525An orally bioavailable inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1...
• MALT1 inhibitor JNJ-67856633An orally bioavailable inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1...
• MALT1 inhibitor MPT-0118An orally bioavailable inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1...
• MALT1 inhibitor ONO-7018An orally bioavailable inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1...
• MALT1 inhibitor SGR-1505A fourth-generation, orally bioavailable, mutant-selective epidermal growth factor receptor (EGFR) inhibitor...
• MaltodextrinAn oligosaccharide derived from starch that is used as a food additive and as a carbohydrate supplement. As a...
• MaltoseA disaccharide consisting of two glucose units linked through an alpha-1,4 glycosidic bond.
• Malva sylvestris/Alcea digitata herbal compoundA traditional Persian medicine composed of Malva sylvestris (M. sylvestris) and Alcea digitata (A. digitata...
• mammaglobin-A DNA vaccineA cancer vaccine containing a plasmid encoding the mammaglobin-A gene with potential immunostimulating and...
• Mammalian target of rapamycinA protein that helps control several cell functions, including cell division and survival, and binds to...
• MammaPrintA lab test that is used to help predict whether breast cancer will come back or spread to other parts of the...
• MammaryHaving to do with the breast.
• Mammary duct ectasiaA benign (not cancer) condition in which a milk duct under the nipple widens and thickens. This can cause the...
• Mammary dysplasiaA group of conditions marked by changes in breast tissue that are benign (not cancer). There are different...
• Mammary glandGlandular organ located on the chest. The mammary gland is made up of connective tissue, fat, and tissue that...
• Mammary Paget diseaseA rare type of breast cancer that involves the nipple and, usually, the areola (the darker circle of skin...
• MammogramAn x-ray image of the breast used to detect signs of breast cancer or other abnormal breast changes. It is...
• MammographyAn imaging method that uses low-dose x-rays to create detailed pictures of the breast. It is used to detect...
• MammoSiteA system used to deliver internal radiation therapy to breast cancer patients after surgery to remove their...
• MAMMOTOMEA device that uses a computer-guided probe to perform breast biopsies. A biopsy procedure using the MAMMOTOME...
• MandibleThe mandible is the largest and strongest bone in the face. It forms the lower part of the jaw and part of...
• Mangafodipir trisodiumThe trisodium salt of mangafodipir with potential antioxidant and chemoprotective activities. Consisting of...
• Manganese chlorideThe dichloride salt of manganese, an essential trace element and a cofactor for many enzymes involved in a...
• Manganese-based MRI contrast agent RVP-001A contrast agent formulation based on the paramagnetic ion Mn2+, stabilized by the chelator PyC3A, that can...
• manganese/L-alanine/vitamin D3-containing contrast agent formulationAn orally bioavailable contrast agent formulation composed of manganese chloride tetrahydrate (MnCl2 4H2O)...
• Manipulative and body-based practiceA type of therapy in which the therapist moves or manipulates one or more parts of the patient’s body. It may...
• MannitolA drug used to decrease swelling of the brain and to treat kidney failure. Mannitol can also be used to open...
• Mantle cell lymphomaAn aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that usually occurs in middle-aged or older...
• Mantle fieldThe area of the neck, chest, and lymph nodes in the armpit that are exposed to radiation.
• Manual healingA type of therapy in which the therapist moves or manipulates one or more parts of the patient’s body. It may...
• Manuka honeyA monofloral honey with potential wound repair and antibacterial activities. Manuka honey is produced by bees...
• MAO inhibitorA type of drug used to treat depression. It stops the breakdown of certain chemicals in the brain that help...
• MAPA rare, inherited disorder in which multiple polyps (abnormal growths) form on the inner walls of the colon...
• MAP2K geneA member of a group of genes that make proteins that send chemical signals from outside the cell to the...
• MapatumumabA substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL R1 on...
• MaplirpaceptA soluble recombinant antibody-like fusion protein composed of the N-terminal CD47 binding domain of human...
• Maprotiline hydrochlorideThe hydrochloride salt form of maprotiline, a tetracyclic antidepressant closely related to the tricyclic...
• Maraba oncolytic virus expressing mutant HPV E6/E7A cancer vaccine comprised of a recombinant, attenuated form of the oncolytic rhabdovirus Maraba (MG1)...
• MaravirocA C-C chemokine receptor type 5 (CCR5) antagonist with activity against human immunodeficiency virus (HIV)...
• MarcaineA drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain...
• MarcellomycinAn antineoplastic oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium...
• MARCKS protein inhibitor BIO-11006An aerosolized 10-amino acid peptide that inhibits the myristoylated alanine rich protein kinase C substrate...
• Marfan syndromeA genetic condition that affects the connective tissue in many organs and tissues in the body, especially the...
• MargenzaA drug used with other drugs to treat adults with HER2-positive breast cancer that has spread to other parts...
• MargetuximabA drug used with other drugs to treat adults with HER2-positive breast cancer that has spread to other parts...
• Margetuximab-cmkbA Fc-domain optimized IgG monoclonal antibody directed against the human epidermal growth factor receptor 2...
• MarginThe edge or border of the tissue removed in cancer surgery. The margin is described as negative or clean when...
• Marginal zone B-cell lymphomaAn indolent (slow-growing) type of B-cell non-Hodgkin lymphoma that begins forming in certain areas (the...
• Marginal zone lymphomaAn indolent (slow-growing) type of B-cell non-Hodgkin lymphoma that begins forming in certain areas (the...
• MaribavirA substance that blocks the ability of viruses to make new viruses and infect cells. It is being studied in...
• MarijuanaThe dried leaves and flowering tops of the Cannabis sativa or Cannabis indica plant. Marijuana contains...
• MarimastatAn anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Marimastat is a matrix...
• MarizomibA naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with...
• MarkerA diagnostic indication that disease may develop.
• MarlotamigA bispecific antibody directed against both human epidermal growth factor receptor (EGFR) and the...
• MART-1 antigenA protein found on normal melanocytes (cells that make the pigment melanin) in the skin and in the retina. It...
• MART-1 reactive CD8+ lymphocytesHuman CD8-positive T-lymphocytes that are engineered to recognize melanoma tumor-associated antigen MART-1...
• MART-1:26-35(27L) peptide vaccineA peptide-based cancer vaccine consisting of amino acid residues 26 through 35 of MART-1 (melanoma antigen...
• MART-1:27-35 peptide vaccineA natural or synthetic peptide cancer vaccine consisting of amino acid residues 27 through 35 of the...
• MART-1/gp100/Tyrosinase/MAGE-A3 peptides-loaded irradiated allogeneic plasmacytoid dendritic cellsIrradiated allogeneic, HLA-A*0201 positive, plasmacytoid dendritic cells (pDCs) loaded with 4 melanoma...
• Masitinib mesylateThe orally bioavailable mesylate salt of masatinib, a multi-targeted protein tyrosine kinase inhibitor with...
• MasofanitenAn orally bioavailable, second-generation inhibitor of the N-terminal domain (NTD) of androgen receptor (AR)...
• MasoprocolA drug put on the skin to treat growths caused by sun exposure. A form of masoprocol that is taken by mouth...
• MassIn medicine, a lump in the body. It may be caused by the abnormal growth of cells, a cyst, hormonal changes...
• Massage therapyA treatment in which the soft tissues of the body are kneaded, rubbed, tapped, and stroked. Massage therapy...
• Massively parallel sequencingA term that describes methods used in the lab to learn the order of building blocks (called nucleotides) for...
• Mast cellA type of white blood cell that is found in connective tissues all through the body, especially under the...
• Mast cell leukemiaA very rare, aggressive (fast-growing) type of systemic mastocytosis in which too many immature mast cells (a...
• Mast cell stabilizer TF002A small molecule with mast cell stabilizing activity. Mast cell stabilizer TF002 inhibits the formation of...
• Mast cell tumorA growth or lump of mast cells (a type of white blood cell). Mast cell tumors can involve the skin...
• MastalgiaPain or discomfort in one or both breasts. The pain can be mild or severe and affect one area of the breast...
• MastectomySurgery to remove part or all of the breast. There are different types of mastectomy that differ in the...
• MastitisA condition in which breast tissue is inflamed. It is usually caused by an infection and is most often seen...
• MastocytomaA growth or lump of mast cells (a type of white blood cell). Mast cell tumors can involve the skin...
• MAT2A inhibitor AG-270An orally available small molecule inhibitor of methionine adenosyltransferase II alpha (MAT2A) with...
• MAT2A inhibitor IDE397An orally bioavailable inhibitor of methionine adenosyltransferase II alpha (MAT2A), with potential...
• MAT2A inhibitor ISM3412An orally bioavailable inhibitor of methionine adenosyltransferase II alpha (MAT2A), with potential...
• MAT2A inhibitor S-095035An orally bioavailable inhibitor of methionine adenosyltransferase II alpha (MAT2A), with potential...
• MaternalHaving to do with the mother, coming from the mother, or related through the mother.
• Matricaria recutita gelA gel-based formulation containing an extract of the herb Matricaria chamomilla (M. recutita or German...
• Matricaria recutita topical infusionA gel-based formulation containing an extract of the herb Matricaria chamomilla (M. recutita or German...
• Matrix metalloproteinaseA member of a group of enzymes that can break down proteins, such as collagen, that are normally found in the...
• Matted lymph nodesA group of fused lymph nodes. Matted lymph nodes may be a sign of certain conditions, such as infection...
• MatulaneA drug used with other drugs to treat advanced Hodgkin lymphoma. It is also being studied in the treatment of...
• Mature T-cell lymphomaOne of a group of aggressive (fast-growing) non-Hodgkin lymphomas that begin in mature T lymphocytes (T cells...
• Mature teratomaA type of germ cell tumor that is usually made up of several different types of tissue, such as hair, muscle...
• MatuzumabA humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor...
• maveropepimut-SA lipid depot-based therapeutic cancer vaccine composed of survivin epitopes, a universal T Helper peptide...
• MavorixaforAn orally bioavailable inhibitor of C-X-C chemokine receptor type 4 (CXCR4), with potential antineoplastic...
• MaxamineA substance being studied in the treatment of some types of cancer and other conditions. When used together...
• MaxillaThe bones that form the upper part of the jaw, the roof of the mouth, and parts of the eye socket and nose...
• Maxillary sinusA type of paranasal sinus (a hollow space in the bones around the nose). There are two large maxillary...
• Maximum inspiratory pressure testA test that measures the strength of the muscles used in breathing. A person inhales and exhales through a...
• Maximum tolerated doseThe highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated...
• Mayo Clinic regimenA chemotherapy combination used to treat colorectal cancer. It is also used with radiation therapy to treat...
• MaytansineAn ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata. Maytansine binds to...
• Maytansinoid DM4-conjugated humanized monoclonal antibody huC242A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal...
• m-azidopyrimethamineAn antifolate derived from diaminopyrimidine with cytotoxic properties. With a mechanism of action similar to...
• MBLA condition in which a higher-than-normal number of identical B cells are found in the blood. People with MBL...
• MC1RA protein found in skin and eye cells that make melanin (a pigment that gives color to the skin and helps...
• MC5-A scrambler therapyA type of treatment for nerve pain that uses electrodes placed on the skin. Electricity is carried from the...
• MCD testA type of blood test that is being studied as a way to screen for many types of cancer at the same time. MCD...
• MCL-1 inhibitor ABBV-467An inhibitor of induced myeloid leukemia cell differentiation protein (myeloid cell leukemia-1; Mcl-1...
• MCL-1 inhibitor AMG 397An inhibitor of induced myeloid leukemia cell differentiation protein (myeloid cell leukemia-1; Mcl-1...
• Mcl-1 inhibitor AZD5991An inhibitor of induced myeloid leukemia cell differentiation protein (myeloid cell leukemia-1; Mcl-1...
• MCL1 inhibitor GS-9716An orally bioavailable inhibitor of the anti-apoptotic protein myeloid cell leukemia 1 (MCL1; induced myeloid...
• Mcl-1 inhibitor MIK665An inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential...
• MCPyV TAg-specific polyclonal autologous CD8-positive T cell vaccineA preparation of polyclonal autologous CD8 positive T-lymphocytes specific for the Merkel cell polyomavirus...
• MCPyV-LT-encoding plasmid DNA vaccine ITI-3000A cancer vaccine consisting of plasmid DNA encoding LTS220A, a truncated form of the large T antigen (LT) of...
• MCT/LCT lipid emulsionA nutritional lipid emulsion consisting of both coconut oil-derived medium chain triglycerides (MCTs) and...
• MCT/LCT/fish oil omega-3 fatty triglyceride lipid emulsionA nutritional lipid emulsion consisting of coconut oil-derived medium chain triglycerides (MCTs), soybean...
• MDL 101,731A drug that belongs to a family of drugs called ribonucleotide reductase inhibitors.
• MDM2 antagonist ASTX295An orally available, small molecule inhibitor of the human homolog of murine double minute 2 (MDM2; HDM2)...
• MDM2 antagonist RO5045337An MDM2 (human homolog of double minutes-2; HDM2) antagonist with potential antineoplastic activity...
• MDM2 antagonist RO6839921An MDM2 (human homolog of murine double minute-2; HDM2) antagonist with potential antineoplastic activity...
• MDM2 degrader KT-253A small molecule protein and selective degrader of the oncoprotein murine double minute 2 (MDM2), with...
• MDM2 inhibitor KRT-232An orally available inhibitor of MDM2 (murine double minute 2), with potential antineoplastic activity. Upon...
• MDM2 inhibitor SA53-OSAn orally bioavailable inhibitor of murine double minute 2 (MDM2), with potential antineoplastic activity...
• MDM2/MDMX inhibitor ALRN-6924An orally available inhibitor of both murine double minute 2 (MDM2) and murine double minute X (MDMX), with...
• MDR modulator CBT-1A substance taken from plants that is being studied in the treatment of cancer. It may help drugs kill tumor...
• MDSA type of cancer in which the bone marrow does not make enough healthy blood cells (white blood cells, red...
• MDX-010A drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better and is used to treat...
• MDX-060A monoclonal antibody that is being studied in the treatment of some lymphomas. Monoclonal antibodies are...
• MeanA statistics term. The average value in a set of measurements. The mean is the sum of a set of numbers...
• Mean survivalThe average length of time from either the date of diagnosis or the start of treatment for a disease, such as...
• Measles virusThe virus that causes measles (a highly contagious disease marked by fever, cough, and raised red spots on...
• Measles/mumps/rubella vaccineA trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella. It is an...
• Measurable diseaseA tumor that can be accurately measured in size. This information can be used to judge response to treatment.
• Measurable residual diseaseA term that is increasingly being used in place of the term minimal residual disease to describe a very small...
• MebendazoleA synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and...
• MecapegfilgrastimA long-acting, pegylated, recombinant analog of the endogenous human granulocyte colony-stimulating factor...
• Mecbotamab vedotinAn antibody-drug conjugate (ADC) composed of a conditionally active biologic (CAB) antibody against AXL...
• Mechanism of actionIn medicine, a term used to describe how a drug or other substance produces an effect in the body. For...
• Mechanistic target of rapamycinA protein that helps control several cell functions, including cell division and survival, and binds to...
• Mechlorethamine hydrochlorideA drug used on the skin to treat stage I mycosis fungoides (a type of cutaneous T-cell lymphoma) in patients...
• Mechlorethamine hydrochloride gelA gel formulation composed of the hydrochloride salt form of mechlorethamine, which is a nitrogen mustard...
• Meclizine hydrochlorideThe hydrochloride salt form of meclizine, a synthetic piperazine with anti-emetic, sedative and histamine H1...
• Meclocycline sulfosalicylateThe sulfosalicylate salt form of meclocycline, a tetracycline antibiotic with broad-spectrum antibacterial...
• Meclofenamate sodiumThe sodium salt form of meclofenamate, an anthranilic acid and non-steroidal anti-inflammatory drug (NSAID)...
• MecobalaminA synthetic and active form of vitamin B12 that can cross the blood brain barrier without biotransformation...
• MEDI-507A substance being studied in the treatment of certain types of T-cell lymphoma. It is also being studied in...
• MEDI-522A substance being studied in the treatment of some types of cancer and other conditions. MEDI-522 binds to a...
• Medial supraclavicular lymph nodeA lymph node located above the collar bone and between the center of the body and a line drawn through the...
• MedianA statistics term. The middle value in a set of measurements.
• Median overall survivalThe length of time from either the date of diagnosis or the start of treatment for a disease, such as cancer...
• Median survivalThe length of time from either the date of diagnosis or the start of treatment for a disease, such as cancer...
• Median umbilical ligamentA fibrous cord that connects the urinary bladder to the umbilicus (navel). The median umbilical ligament is...
• Mediastinal pleuraThe thin membrane that lines the chest cavity in the area between the lungs.
• MediastinoscopeA thin, tube-like instrument used to examine the tissues and lymph nodes in the area between the lungs. These...
• MediastinoscopyA procedure in which a mediastinoscope is used to examine the organs in the area between the lungs and nearby...
• MediastinumThe area between the lungs. The organs in this area include the heart and its large blood vessels, the...
• MedicaidA public health insurance program for some people or families with limited incomes and resources, including...
• Medical castrationRefers to the use of drugs to suppress the function of the ovaries or testicles.
• Medical deviceAn instrument, tool, machine, test kit, or implant that is used to prevent, diagnose, or treat disease or...
• Medical historyA record of information about a person’s health. A personal medical history may include information about...
• Medical nutrition therapyA nutrition-based treatment plan to help manage or treat certain health conditions. These include diabetes...
• Medical oncologistA doctor who has special training in diagnosing and treating cancer in adults using chemotherapy, hormonal...
• Medical power of attorneyA type of advance directive that gives a person (called a proxy) the authority to make medical decisions for...
• MedicareA U.S. federal health insurance program for people aged 65 and older and some people younger than 65 with...
• Medicare Part DA type of insurance that helps people with Medicare pay for prescription drugs. People with Medicare Part D...
• Medicare Prescription Drug CoverageA type of insurance that helps people with Medicare pay for prescription drugs. People with Medicare...
• Medicated urethral system for erectionA method used to treat impotence (inability to have an erection). A suppository, in the form of a very small...
• MedicationA dosage form that contains one or more active and/or inactive ingredients. Medications come in many dosage...
• MedicineRefers to the practices and procedures used for the prevention, treatment, or relief of symptoms of diseases...
• MeditationA mind-body practice in which a person focuses his or her attention on something, such as an object, word...
• Medroxyprogesterone acetateA drug used to prevent endometrial cancer. It is also used to treat menstrual disorders and as a form of...
• M-EDTAA substance being studied in the prevention of bacterial infections that occur in catheters (thin tubes that...
• Medullary breast carcinomaA rare type of breast cancer that often can be treated successfully. It is marked by lymphocytes (a type of...
• Medullary thyroid cancerCancer that develops in C cells of the thyroid. The C cells make a hormone (calcitonin) that helps maintain a...
• MedulloblastomaA fast-growing type of cancer that forms in the cerebellum (the lower, back part of the brain)...
• MefloquineA quinolinemethanol derivative with antimalarial, anti-inflammatory, and potential chemosensitization and...
• Mega-voltage linear acceleratorA machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy...
• Megestrol acetateA drug used in tablet form to relieve the symptoms of advanced breast cancer and endometrial cancer. It is...
• MeiosisA special form of cell division in which each daughter cell receives half the amount of DNA as the parent...
• MEK 1/2 inhibitor AS703988/MSC2015103BAn orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK...
• MEK 1/2 inhibitor FCN-159An orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK kinase, or MEK)...
• MEK geneA member of a group of genes that make proteins that send chemical signals from outside the cell to the...
• MEK inhibitorA substance that blocks proteins called MEK1 and MEK2, which help control cell growth and survival. Blocking...
• MEK inhibitor AZD6244A drug used to treat children aged 2 years and older with a rare genetic condition called neurofibromatosis...
• MEK inhibitor AZD8330An orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor AZD8330...
• MEK inhibitor BI 3011441An orally bioavailable, small-molecule, allosteric inhibitor of mitogen-activated protein kinase kinase...
• MEK inhibitor CS3006An orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase (MAP2K; MAPKK...
• MEK inhibitor GDC-0623An orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor GDC-0623...
• MEK inhibitor IMM-1-104An orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MAP2K; MAPK/ERK kinase; MEK) 1...
• MEK inhibitor IMM-6-415An orally bioavailable small molecule and deep cyclic inhibitor (DCI) of mitogen-activated protein kinase...
• MEK inhibitor NFX-179A topical gel formulation composed of an inhibitor of mitogen-activated protein kinase kinase (MAP2K; MAPKK...
• MEK inhibitor REC-4881An orally bioavailable, non-ATP-competitive, allosteric, small-molecule inhibitor of mitogen-activated...
• MEK inhibitor RO4987655An orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with...
• MEK inhibitor SHR 7390An orally available small molecule inhibitor of mitogen-activated protein kinase kinase (MAP2K; MAPK/ERK...
• MEK inhibitor WX-554An orally available small molecule mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK kinase, or MEK)...
• MEK1 proteinA protein involved in a cell signaling pathway that helps control cell division, cell maturation, and cell...
• MEK1/2 inhibitor ABM-168An orally bioavailable, brain-penetrant, allosteric inhibitor of mitogen-activated protein kinase kinase...
• MEK1/2 inhibitor PAS-004An orally bioavailable macrocyclic inhibitor of mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK...
• MEK-1/MEKK-1 inhibitor E6201A synthetic, fungal metabolite analogue inhibitor of mitogen-activated protein kinase kinase 1 (MEK-1) and...
• MEK2 proteinA protein involved in a cell signaling pathway that helps control cell division, cell maturation, and cell...
• MEK/Aurora kinase dual inhibitor BI 847325An orally available dual inhibitor of mitogen-activated protein kinase kinase (MEK) and Aurora kinases, with...
• MekinistA drug used alone or with dabrafenib to treat low-grade glioma (a type of brain tumor) in children aged 1...
• MEK/RAF molecular glue IK-595An orally bioavailable mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK kinase, or MEK)/RAF molecular...
• MektoviA drug used with encorafenib to treat melanoma that has spread or cannot be removed by surgery and has a...
• Melan-A proteinA protein found on normal melanocytes (cells that make the pigment melanin) in the skin and in the retina. It...
• Melan-A VLP vaccineA vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in...
• melan-A/MAGE-3.DP4 peptide vaccineA cancer vaccine consisting of a peptide derived from the melanocyte differentiation antigen Melan-A (or...
• MelaninA pigment that gives color to skin and eyes and helps protect it from damage by ultraviolet light.
• Melanocortin 1 receptorA protein found in skin and eye cells that make melanin (a pigment that gives color to the skin and helps...
• MelanocyteA cell in the skin and eyes that produces and contains the pigment called melanin.
• Melanocytic macules associated with Peutz-Jeghers syndromeBenign pigmented patches that are commonly found on the lips. They may also be found inside the mouth, on the...
• MelanomaA form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole...
• Melanoma and neural system tumor syndromeAn extremely rare, inherited disorder in which affected people have an increased risk of developing melanoma...
• Melanoma Antigen Recognized by T cells 1A protein found on normal melanocytes (cells that make the pigment melanin) in the skin and in the retina. It...
• Melanoma helper peptide vaccineA multivalent vaccine consisting of peptides derived from melanoma-associated antigens and an adjuvant...
• Melanoma in situAbnormal melanocytes (cells that make melanin, the pigment that gives skin its natural color) are found in...
• Melanoma TRP2 CTL epitope vaccine SCIB1A proprietary DNA-based cancer vaccine that encodes a melanoma antigen tyrosinase-related protein 2 (TRP2)...
• Melanoma vaccineA cancer vaccine prepared from human melanoma cancer cells. It can be used alone or with other therapy in...
• Melanoma-astrocytoma syndromeAn extremely rare, inherited disorder in which affected people have an increased risk of developing melanoma...
• Melanotropin receptorA protein found in skin and eye cells that make melanin (a pigment that gives color to the skin and helps...
• MelatoninA hormone made by the pineal gland (tiny organ near the center of the brain). Melatonin helps control the...
• Melia azadirachta flower extractThe flower extract from the tree Melia azadirachta.
• MELITAC 12.1 peptide vaccineA peptide cancer vaccine consisting of an emulsion of a mixture of 12 class I MHC-restricted melanoma...
• MELK inhibitor OTS167An orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential...
• MeloxicamAn oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic...
• MelphalanA drug used to treat multiple myeloma and ovarian epithelial cancer that cannot be removed by surgery. It is...
• Melphalan flufenamideA peptide-drug conjugate composed of a peptide conjugated, via an aminopeptidase-targeting linkage, to the...
• Melphalan flufenamide hydrochlorideThe hydrochloride salt form of the peptide-drug conjugate melphalan flufenamide in which the flufenamide...
• Melphalan hydrochlorideA drug used to treat certain types of multiple myeloma and uveal melanoma (a type of eye cancer). An infusion...
• Melphalan hydrochloride/sulfobutyl ether beta-cyclodextrin complexA propylene glycol-free intravenous formulation containing the hydrochloride salt of the nitrogen mustard...
• MemantineA low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine...
• Memantine hydrochlorideA drug used to treat dementia caused by Alzheimer disease. It is also being studied in the treatment of side...
• MembraneA very thin layer of tissue that covers a surface.
• Membrane-bound IL-15-expressing Tumor-infiltrating Lymphocytes OBX-115A preparation of tumor-infiltrating lymphocytes (TILs) that have been genetically engineered to express...
• Membrane-bound interleukin-21-expanded haploidentical natural killer cellsA preparation of human cytokine interleukin-21 (IL-21) primed, tumor-activated allogeneic human leukocyte...
• MEN syndromeAn inherited condition that may result in the development of cancers of the endocrine system. There are...
• MEN1 syndromeA rare, inherited disorder that affects the endocrine glands and can cause tumors in the parathyroid and...
• MEN-10755An anticancer drug that belongs to the family of drugs called antitumor antibiotics.
• MEN2A rare, genetic disorder that affects the endocrine glands and can cause tumors in the thyroid gland...
• MEN2 syndromeA rare, genetic disorder that affects the endocrine glands and can cause tumors in the thyroid gland...
• MEN2AA rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called...
• MEN2A syndromeA rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called...
• MEN2BA rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called...
• MEN2B syndromeA rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called...
• Menadione topical lotionA topical lotion containing the small organic molecule protein tyrosine phosphatase (PTP) inhibitor menadione...
• MenatetrenoneA menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act...
• Ménétrier diseaseA condition marked by inflammation and ulcers (breaks on the skin or on the surface of an organ) of the...
• Menin inhibitorA substance that binds to a protein called menin and keeps it from binding to another protein called MLL...
• Menin inhibitor BMF-219An orally bioavailable, irriversible inhibitor of menin, an essential co-factor of oncogenic menin-mixed...
• Menin inhibitor DS-1594bAn orally bioavailable small molecule inhibitor of menin, with potential antineoplastic activity. Upon oral...
• Menin inhibitor DSP-5336An orally bioavailable, small molecule inhibitor of menin, with potential antineoplastic activity. Upon oral...
• MeningealHaving to do with the meninges (three thin layers of tissue that cover and protect the brain and spinal cord).
• Meningeal carcinomatosisA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• Meningeal leukemiaA serious problem that may occur in leukemia. In meningeal leukemia, cancer cells have spread from the...
• Meningeal metastasisA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• Meningeal syndromeA condition marked by headache, fever, and a stiff neck, which is caused when the meninges (three thin layers...
• MeningesThe three thin layers of tissue that cover and protect the brain and spinal cord.
• MeningiomaA type of slow-growing tumor that forms in the meninges (thin layers of tissue that cover and protect the...
• MeningitisInflammation of the meninges (three thin layers of tissue that cover and protect the brain and spinal cord)...
• Meningococcal diseaseA serious disease caused by infection with bacteria called Neisseria meningitidis. The bacteria can invade...
• Meningococcal vaccineA vaccine that helps protect the body against infection with certain types of Neisseria meningitidis bacteria...
• menin-MLL interaction inhibitor JNJ-75276617An orally bioavailable protein-protein interaction (PPI) inhibitor of the menin-mixed lineage leukemia (MLL...
• MenogarilA semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates...
• Menopausal hormone therapyTreatment with the hormones estrogen and progesterone or with estrogen alone to help relieve symptoms of...
• MenopauseThe time of life when a woman’s ovaries stop producing hormones and menstrual periods stop. Natural menopause...
• MenorrhagiaAbnormally heavy menstrual bleeding.
• MensesThe normal monthly shedding of blood and tissue from the lining of the uterus (womb) when pregnancy does not...
• Menstrual cycleThe monthly cycle of hormonal changes from the beginning of one menstrual period to the beginning of the...
• Menstrual periodThe normal monthly shedding of blood and tissue from the lining of the uterus (womb) when pregnancy does not...
• MenstruationThe normal monthly shedding of blood and tissue from the lining of the uterus (womb) when pregnancy does not...
• Mental healthA person’s overall psychological and emotional condition. Good mental health is a state of well-being in...
• Mental health counselorA specialist who talks to patients and their families about emotional and personal matters, and can help them...
• MentholA substance that comes from mint oils or is made in the laboratory. It is used to relieve itching and to...
• MEPACTA drug being studied in the treatment of young adults with bone cancer that has gotten worse or come back...
• Meperidine hydrochlorideA drug used to treat moderate to severe pain. Meperidine hydrochloride works by binding to opioid receptors...
• Mepivacaine hydrochlorideThe hydrochloride salt form of mepivacaine, an amide-type local anesthetic agent. At the injection site...
• MepolizumabA humanized immunoglobulin G1 (IgG1) monoclonal antibody directed against interleukin-5 (IL-5) with...
• MercaptopurineA drug used with other drugs to treat adults and children with acute lymphoblastic leukemia. It is also being...
• Mercaptopurine oral suspensionAn oral suspension containing the thiopurine-derivative antimetabolite 6-mercaptopurine, with potential...
• Mercaptopurine tabletThe anhydrous form of mercaptopurine, a thiopurine-derivative antimetabolite with antineoplastic and...
• MercuryA silver-white, poisonous metal that is a liquid at ordinary temperatures. It is commonly used in...
• Mercy killingAn easy or painless death, or the intentional ending of the life of a person suffering from an incurable or...
• MerestinibAn orally available, small molecule inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor...
• MeridianIn traditional Chinese medicine, one of 20 channels that form a network through which qi (the body's vital...
• Merkel cellA special type of cell found right below the epidermis (top layer of skin). These cells are very close to the...
• Merkel cell cancerA rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been...
• Merkel cell carcinomaA rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been...
• MeropenemA broad-spectrum carbapenem with antibacterial properties, synthetic Meropenem inhibits cell wall synthesis...
• MesalamineAn agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through...
• MesenchymalRefers to cells that develop into connective tissue, blood vessels, and lymphatic tissue.
• Mesenchymal stem cellsAn undifferentiated stromal cell with the ability to develop into the cells that form distinct mesenchymal...
• Mesenchymal stromal cells-derived exosomes with KRAS G12D siRNAExosomes derived from mesenchymal stromal cells (MSCs) that have been engineered to carry short interfering...
• Mesenteric membraneThe peritoneal membrane that attaches the intestines to the abdominal wall near the back.
• Mesmulogene ancovacivecA bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1...
• MesnaA drug used to prevent hemorrhagic cystitis (bleeding in the bladder) caused by the anticancer drug...
• MesnexA drug used to prevent hemorrhagic cystitis (bleeding in the bladder) caused by the anticancer drug...
• MesothelinA protein found on the surface of certain types of normal cells and cancer cells. Mesothelin may help these...
• mesothelin/CD3e tri-specific T-cell activating construct HPN536A recombinant antibody derivative composed of a tri-specific T-cell activating construct (TriTAC) directed...
• Mesothelin-specific chimeric antigen receptor-engineered peripheral blood lymphocytesA preparation of peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T cell...
• MesotheliomaA benign (not cancer) or malignant (cancer) tumor affecting the lining of the chest or abdomen. Exposure to...
• Mesothelioma tumor lysate-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor...
• Messenger RNAA type of RNA found in cells. Messenger RNA molecules carry the genetic information needed to make proteins...
• MET geneA gene that makes a protein that is involved in sending signals within cells and in cell growth and survival...
• MET kinase inhibitor OMO-1An inhibitor of the proto-oncogene and receptor tyrosine kinase (RTK) hepatocyte growth factor receptor...
• MET receptor tyrosine kinase inhibitor SGX523An orally bioavailable small molecule, belonging to the class of c-Met/hepatocyte growth factor receptor...
• Met tyrosine kinase inhibitor BMS-777607An inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor...
• MET tyrosine kinase inhibitor EMD 1204831An inhibitor of the receptor tyrosine kinase MET (hepatocyte growth factor receptor) with potential...
• MET tyrosine kinase inhibitor PF-04217903An orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte...
• MET tyrosine kinase inhibitor SAR125844An inhibitor of the proto-oncogene c-Met (also known as hepatocyte growth factor receptor [HGFR]) with...
• MET x MET bispecific antibody REGN5093A bispecific monoclonal antibody that targets two different epitopes of the human tumor-associated antigen...
• Meta-analysisA process that analyzes data from different studies done about the same subject. The results of a...
• MetabolicHaving to do with metabolism (the total of all chemical changes that take place in a cell or an organism to...
• Metabolic acidosisA condition in which the blood is too acidic. It may be caused by severe illness or sepsis (bacteria in the...
• Metabolic anti-cancer agent ASCA101An agent targeting cancer metabolic processes, with potential antineoplastic activity. Upon administration...
• Metabolic disorderA condition in which normal metabolic processes are disrupted, usually because of a missing enzyme.
• Metabolic syndromeA condition marked by extra fat around the abdomen, high levels of blood glucose (sugar) when not eating...
• Metabolic syndrome XA condition marked by extra fat around the abdomen, high levels of blood glucose (sugar) when not eating...
• Metabolic therapyTreatment to correct changes in metabolism that can be caused by disease.
• Metabolic typeIn alternative medicine, a theory that people fall into one of three groups (protein, carbohydrate, or mixed...
• MetabolismThe chemical changes that take place in a cell or an organism. These changes make energy and the materials...
• MetaboliteA substance made or used when the body breaks down food, drugs or chemicals, or its own tissue (for example...
• MetabolomicsThe study of substances called metabolites in cells and tissues. Metabolites are small molecules that are...
• Metachronous cancerA term used to describe a new or second primary cancer that develops months or years after a first primary...
• Meta-fluorine F 18 fluorobenzylguanidineA radioconjugate composed of the positron-emitting radioisotope fluorine F 18 labeled benzylguanidine, a...
• MetahexamideA long-acting, first-generation, cyclohexyl sulfonylurea with antihyperglycemic activity. Metahexamide has...
• Metaiodobenzylguanidine scanA procedure used to find neuroendocrine tumors, such as neuroblastomas and pheochromocytomas. A small amount...
• MetallicHaving to do with metal. Some cancer treatments may change the sense of taste and cause foods to have a...
• Metallic endoprosthesisA device made of metal that is placed inside the body to replace a body part removed by surgery. An example...
• MetAP2 inhibitor APL-1202An orally available inhibitor of methionine aminopeptidase II type (MetAP2) with potential antiangiogenic and...
• MetaplasiaA change of cells to a form that does not normally occur in the tissue in which it is found.
• Metaplastic carcinomaA general term used to describe cancer that begins in cells that have changed into another cell type (for...
• MetarrestinAn orally available small molecule inhibitor of perinucleolar compartment (PNC), with potential...
• MetastasectomySurgery to remove one or more metastases (tumors formed from cells that have spread from the primary tumor)...
• MetastasisThe spread of cancer cells from the place where they first formed to another part of the body. In metastasis...
• Metastasis-free survivalThe length of time from the start of treatment for cancer that a patient is still alive and the cancer has...
• MetastasizeTo spread from one part of the body to another. When cancer cells metastasize and form secondary tumors, the...
• MetastaticHaving to do with metastasis, which is the spread of cancer from the primary site (place where it started) to...
• MetasynchronousOccurring at nearly the same time.
• Metatinib tromethamineAn orally bioavailable tyrosine kinase inhibitor of the BCR-ABL fusion oncoprotein, with potential...
• MeteorismSwelling of the abdomen caused by gas in the intestines or peritoneal cavity. Also called tympanites.
• Metformide hydrochloride/pioglitazone hydrochloride extended-release tabletAn extended-release (ER) tablet composed of the hydrochloride salt form of the biguanide metformin and the...
• Metformin hydrochlorideA drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in...
• Methadone hydrochlorideA drug used to treat moderate to severe pain. It is also used to help people who are addicted to opioid...
• MethanolA type of alcohol used to make antifreeze, pesticides, windshield wiper fluid, paint thinner, certain types...
• Methanol extraction residue of BCGA cell wall fraction of bacillus Calmette-Guerin (BCG) obtained by menthol extraction with immunomodulating...
• MethazolamideA sulfonamide derivate and carbonic anhydrase inhibitor with potential antineoplastic activity. Methazolamide...
• MethemoglobinA form of hemoglobin found in the blood in small amounts. Unlike normal hemoglobin, methemoglobin cannot...
• MethemoglobinemiaA condition in which a higher-than-normal amount of methemoglobin is found in the blood. Methemoglobin is a...
• Methicillin-resistant Staphylococcus aureusA type of bacteria that causes an infection that does not respond to common antibiotics, including...
• MethimazoleA thioamide inhibitor of the enzyme thyroid peroxidase (TPO), with antithyroid activity. Upon administration...
• Methionine aminopeptidase 2 inhibitor M8891A proprietary orally available inhibitor of methionine aminopeptidase 2 (MetAP2), which cleaves the...
• Methionine C 11A synthetic amino acid radiolabeled with carbon-11. Acting as a methyl donor, methionine C 11 is incorporated...
• MethodologyIn medicine, the rules and procedures for doing research and evaluating results.
• MethotrexateAn antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate...
• Methotrexate sodiumA drug used alone or with other drugs to treat many types of cancer, certain types of arthritis, and severe...
• Methotrexate-e therapeutic implantAn injectable collagen matrix gel containing the antimetabolite methotrexate and the sympathicomimetic agent...
• Methotrexate-encapsulating autologous tumor-derived microparticlesA suspension of autologous tumor-derived microparticles (ATMP), that are harvested from a patient with...
• MethoxsalenA drug used together with UV light to treat psoriasis, vitiligo, and skin nodules of cutaneous T-cell...
• MethoxyamineAn orally bioavailable small molecule inhibitor with potential adjuvant activity. Methoxyamine covalently...
• Methoxyamine hydrochlorideA substance being studied in the treatment of cancer. It blocks the ability of a cell to repair damage to its...
• MethoxyfluraneA fluorinated isopropyl ether with anesthetic and muscle relaxant activities. Although the mechanism of...
• Methoxypolyethylene glycol epoetin betaA substance being studied in the treatment of anemia in patients who are receiving chemotherapy. It is a form...
• Methyl alcoholA type of alcohol used to make antifreeze, pesticides, windshield wiper fluid, paint thinner, certain types...
• Methyl bacteriopurpurinimideA brain-penetrant bacteriochlorin analog and photosensitizer, with potential imaging and antineoplastic...
• Methyl groupA small molecule made of one carbon and three hydrogen atoms. Methyl groups are added or removed from...
• methyl-5-aminolevulinateA drug used in photodynamic therapy; it is absorbed by tumor cells and, when exposed to light, becomes active...
• methyl-5-aminolevulinate hydrochloride creamA topical cream formulation containing the hydrochloride salt of methyl-5-aminolevulinate, a lipophilic...
• MethylationA chemical reaction in the body in which a small molecule called a methyl group gets added to DNA, proteins...
• MethylcantharidimideAn orally bioavailable derivative of the terpenoid cantharidin, which is a natural toxin extracted from...
• Methylene blueA synthetic basic dye. Methylene blue stains to negatively charged cell components like nucleic acids; when...
• Methylene dimethane sulfonateA member of the homologous series of dimethane sulphonic acid esters with alkylating properties. Methylene...
• Methylmercaptopurine ribosideA purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside...
• MethylnaltrexoneA methyl derivative of noroxymorphone with selective, opioid-receptor antagonistic activity. Methylnaltrexone...
• Methylnaltrexone bromideA drug used to relieve constipation caused by the use of opioids (pain killers that are like morphine). It is...
• Methylphenidate hydrochlorideA drug used to treat certain behavior disorders, such as attention deficit hyperactivity disorder (ADHD). It...
• MethylprednisoloneA corticosteroid hormone replacement.
• Methylprednisolone acetateThe acetate salt of a synthetic glucocorticoid receptor agonist with immunosuppressive and antiinflammatory...
• MethylselenocysteineA naturally occurring organoselenium compound found in many plants, including garlic, onions, and broccoli...
• MethyltestosteroneA methylated synthetic androgen receptor agonist with anabolic effects. Methyltestosterone, mimicking...
• MetoclopramideA drug that increases the motility (movements and contractions) of the stomach and upper intestine. It is...
• Metoclopramide hydrochlorideThe hydrochloride salt of the substituted benzamide metoclopramide, a para-aminobenzoic acid (PABA)...
• MetoprineA diaminopyrimidine folate antagonist with potential antineoplastic activity. Metoprine inhibits...
• MetoprololA cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and...
• Metoprolol succinateThe succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist...
• Metoprolol tartrateThe tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist...
• MetreleptinA recombinant human leptin analog composed of human leptin with the addition of a methionine residue at its...
• MetronidazoleA drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of...
• Metronidazole hydrochlorideThe hydrochloride salt of a synthetic nitroimidazole derivative with antiprotozoal and antibacterial...
• Metronomic chemotherapyTreatment in which low doses of anticancer drugs are given on a continuous or frequent, regular schedule...
• METTL-3 inhibitor STC-15An orally bioavailable methyltransferase-like protein 3 (METTL-3) inhibitor, with potential antineoplastic...
• MET/VEGFR-2 inhibitor GSK1363089A substance being studied in the treatment of cancer. MET/VEGFR-2 inhibitor GSK1363089 blocks enzymes...
• MetyrosineA methylated tyrosine, a catecholamine synthesis antagonist with antihypertensive property. Metyrosine...
• MeV linear acceleratorA machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy...
• MevacorA drug used to lower the amount of cholesterol in the blood. It is also being studied in the prevention and...
• Mevalonate pathwayDescribes a series of reactions in which proteins work together to make molecules. These molecules are part...
• Mexican valerianA plant whose roots are used as a sedative and to treat certain medical conditions. It is being studied as a...
• MexiletineA local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. Mexiletine exerts...
• Mexiletine hydrochlorideThe hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent...
• MezigdomideA modulator of the E3 ubiquitin ligase complex containing cereblon (CRL4-CRBN E3 ubiquitin ligase), with...
• MFSThe length of time from the start of treatment for cancer that a patient is still alive and the cancer has...
• MG 98A second-generation, mixed-backbone, phosphorothioate antisense oligonucleotide (ODN) with potential...
• MG98A substance being studied in the treatment of cancer. It blocks the production of a protein called DNA...
• MGCD0103A substance being studied in the treatment of several types of cancer. It blocks enzymes needed for cell...
• MGPTA laboratory test in which many genes are studied in a sample of tissue. MGPTs help find mutations (changes)...
• MGUSA benign condition in which there is a higher-than-normal level of a protein called M protein in the blood...
• MHTTreatment with the hormones estrogen and progesterone or with estrogen alone to help relieve symptoms of...
• MIBG scanA procedure used to find neuroendocrine tumors, such as neuroblastomas and pheochromocytomas. A small amount...
• MicafunginA semi-synthetic echinocandin derived from a natural product of the fungus Coleophama empedri with potent...
• Micellar nanoparticle-encapsulated cisplatin NC-6004A nanoparticle-based prodrug formulation consisting of polymeric micelles incorporating the inorganic...
• Micellar nanoparticle-encapsulated epirubicinA nanoparticle-based prodrug formulation consisting of polymeric micelles encapsulating the anthracycline...
• MicelleA tiny particle made of substances that are soluble in water and that come together to form a ball-like...
• Michelia alba leaf oilA steam distilled essential oil composed of the oil from the leaves of the Michelia alba (MA) plant belonging...
• Micro needle array-doxorubicinA formulation composed of dissolvable small, adhesive-like patches composed of a biocompatible material which...
• MicroarrayA laboratory tool used to analyze large numbers of genes or proteins at one time. In a microarray, biologic...
• Microbial ecosystem therapeutics-4An orally available formulation consisting of a well-defined mixture of over thirty intestinal bacteria...
• MicrobicideAny substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause...
• MicrobiomeThe collection of all the microorganisms and viruses that live in a given environment, including the human...
• Microbiome GEN-001A microbiome therapeutic composed of a single-strain bacterium, isolated from the gut of healthy donors, with...
• Microbiome SER-155An orally bioavailable, cultivated microbiome therapeutic composed of a consortium of fermented bacterial...
• Microbiome SER-401A donor-derived microbiome therapeutic composed of a combination of as of yet not disclosed microbes that...
• Microbiome-derived peptide vaccine EO2040An off-the-shelf (OTS), microbiome therapeutic cancer peptide vaccine composed of two onco-mimics, which are...
• Microbiome-derived peptide vaccine EO2401A donor-derived, off-the-shelf, microbiome therapeutic cancer peptide vaccine composed of three bacterial...
• Microbiome-derived peptide vaccine EO2463A microbiome therapeutic cancer peptide vaccine composed of onco-mimics, immunogenic microbiome-derived...

1,028 of 17,717 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.