M87o-transduced CD34+ peripheral blood stem cells

{
  "id": "MLC-T-ONC-014954",
  "term": "M87o-transduced CD34+ peripheral blood stem cells",
  "field": "Oncology and biomedicine",
  "definition": "Peripheral blood stem cells (PBSCs) transduced with the retroviral vector M87o encoding for the HIV-1-entry inhibitor peptide membrane-anchored antiviral peptide C46 (maC46). Expression of C46 by M87o-transduced CD34+ peripheral blood stem cells may prevent the fusion of viral and cellular membranes, thereby inhibiting HIV-1 entry. C46 is a membrane-anchored peptide encoding amino acids 628 to 673 of the HIV-1 entry inhibitory transmembrane glycoprotein gp41.",
  "synonyms": [
    "therapeutic gamma-retroviral vector M87o-transduced CD34+ peripheral blood stem cells",
    "M87o-transduced CD34+ PBSC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/m87o-transduced-cd34-plus-peripheral-blood-stem-cells/"
}