Menogaril
Term · Oncology and biomedicine · MLC-T-ONC-015094
A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin.
| Identifier | MLC-T-ONC-015094 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | 7-OMEN |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-015094",
"term": "Menogaril",
"field": "Oncology and biomedicine",
"definition": "A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin.",
"abbreviation": "7-OMEN",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/menogaril/"
}
Record 10,844 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.