MLchartDataset catalogue

13-deoxydoxorubicin

Term · Oncology and biomedicine · MLC-T-ONC-009515

An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.

Table 1. Record
IdentifierMLC-T-ONC-009515
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-009515",
  "term": "13-deoxydoxorubicin",
  "field": "Oncology and biomedicine",
  "definition": "An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/13-deoxydoxorubicin/"
}

Record 18 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.