Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: L (655)

Page 1 of 2

• LA measure of volume for a liquid, using the metric system. One L is equal to 1,000 cubic centimeters (cc)...
• L-3,5,5’-tetraiodothyronineA hormone that is made by the thyroid gland and contains iodine. L-3,5,5’-tetraiodothyronine increases the...
• L-377,202A substance that is being studied in the treatment of cancer.
• L-778,123An anticancer drug that belongs to the family of drugs called enzyme inhibitors. It may inhibit the...
• labetuzumab-SN-38 immunoconjugate IMMU-130An antibody-drug conjugate (ADC) containing labetuzumab, a mildly reduced, anti-CEACAM5 humanized monoclonal...
• labial mucosaThe inner lining of the lips.
• lab-on-a-chipAn instrument that uses very small amounts of fluid on a microchip to do certain laboratory tests. A...
• laboratory studyResearch done in a laboratory. A laboratory study may use special equipment and cells or animals to find out...
• laboratory testA medical procedure that involves testing a sample of blood, urine, or other substance from the body...
• labyrinthin peptide vaccine LabVax 3(22)-23A synthetic peptide vaccine composed of four synthetic peptide epitopes of the tumor-associated antigen (TAA)...
• lacosamideA functionalized amino acid compound specifically synthesized as an anticonvulsive drug to use as add-on...
• lacrimal glandA gland that secretes tears. The lacrimal glands are found in the upper, outer part of each eye socket.
• lactaseAn enzyme that breaks down lactose, a type of sugar found in milk and milk products.
• lactate dehydrogenaseOne of a group of enzymes found in the blood and other body tissues and involved in energy production in...
• lactationThe process of making and secreting milk from the mammary glands in the breasts. Lactation usually begins...
• lactic acidA substance made from sugars in milk, by the action of certain enzymes. It is used in skin care products to...
• lactic acid dehydrogenaseOne of a group of enzymes found in the blood and other body tissues, and involved in energy production in...
• lactobacillusA type of bacterium that makes lactic acid (a substance that is made from sugars found in milk and is also...
• Lactobacillus acidophilus/estriol vaginal tabletA vaginal tablet containing a low dose of the estrogen hormone estriol and lyophilized Lactobacillus...
• Lactobacillus acidophilus/Streptococcus thermophilus/Bifidobacterium lactis/L. rhamnosus/B. longum/B. bifidum-based probiotic supplementA nutritional supplement containing probiotic cultures of Lactobacillus acidophilus (L. acidophilus), L...
• Lactobacillus brevis CD2 lozengeA lozenge containing an extract from the Lactobacillus brevis (L. brevis) with potential anti-inflammatory...
• Lactobacillus bulgaricus,/Bifidobacterium longum/Streptococcus thermophilus-based probiotic mixtureA nutritional supplement containing probiotic cultures of Lactobacillus bulgaricus, Bifidobacterium longum...
• Lactobacillus crispatus M247 supplementA supplement containing the probiotic strain Lactobacillus crispatus M247, with potential protective...
• lactobacillus fermented extractA proprietary dietary supplement. Lactobacillus fermented extract is made from soymilk fermented by several...
• Lactobacillus fermentum strain HEM 1036A nutritional supplement containing a probiotic strain of the Gram-positive bacterium Lactobacillus (L.)...
• Lactobacillus plantarum 299v/Lactobacillus acidophilus/Bifidobacterium lactis probiotic supplementA powder-based, probiotic supplement drink containing the non-pathogenic microorganisms Lactobacillus...
• Lactobacillus plantarum strain 299A nutritional supplement containing the probiotic bacterium Lactobacillus plantarum 299 (Lp 299) with...
• Lactobacillus plantarum strain 299vA nutritional supplement containing a strain of the probiotic bacterium Lactobacillus plantarum 299v (Lp...
• Lactobacillus probiotic BSL_PS6A probiotic composed of a strain of the Gram-positive, naturally-occurring bacterium Lactobacillus, with...
• Lactobacillus reuteri probiotic lozengeAn oral lozenge containing the DSM 17938 and ATCC PTA 5289 strains of the probiotic Gram-positive, naturally...
• Lactobacillus reuteri probiotic tabletA tablet containing a strain of the probiotic Gram-positive, naturally-occurring bacterium Lactobacillus...
• Lactobacillus rhamnosus GGA live form of a bacterium that makes lactic acid (a substance that is made from sugars found in milk and is...
• Lactobacillus rhamnosus/L. acidophilus/L. plantarum/Enterococcus faecium aqueous probiotic supplementA water-based multi-strain probiotic composed of an extract of germinated barley containing the four live...
• Lactobacillus rhamnosus/L. jensenii/L. crispatus/L. gasseri oral supplementA nutritional supplement containing the probiotic Lactobacillus strains L. rhamnosus, L. jensenii, L...
• Lactobacillus rhamnosus/Lactobacillus reuteri probiotic supplementA probiotic supplement containing the bacteria Lactobacillus (L.) rhamnosus and L. reuteri, with potential...
• Lactobacillus vaginalis-containing vaginal capsuleA vaginal capsule formulation containing the lactic acid-producing bacterium Lactobacillus vaginalis (L...
• Lactobacillus-based probiotic capsuleA capsule containing a strain of the probiotic bacterium Lactobacillus with potential antimicrobial and...
• lactoferrinA protein that is found in milk, tears, mucus, bile, and some white blood cells and is being studied in the...
• lactoseA type of sugar found in milk and milk products.
• lactose intoleranceThe inability to digest or absorb lactose, a type of sugar found in milk and other dairy products.
• lacutamabA humanized monoclonal antibody against the immune receptor human killer cell immunoglobulin-like receptor...
• ladarixin sodiumThe sodium salt form of ladarixin, an orally bioavailable, small molecule, dual inhibitor of C-X-C motif...
• ladiratuzumab vedotinAn antibody-drug conjugate (ADC) composed of a humanized monoclonal antibody directed against the anti-solute...
• laetrileA purified form of amygdalin made in the laboratory. Amygdalin is a substance found in the pits of some...
• LAIR-2 fusion protein NC410A fusion protein of leukocyte-associated immunoglobulin (Ig)-like receptor (LAIR)-2, a high-affinity collagen...
• LAK cellA white blood cell that is stimulated in a laboratory to kill tumor cells. Also called lymphokine-activated...
• LAMA3 geneA gene that makes one of the three subunits of a protein involved in cell growth, cell movement, and cell...
• LAMB3 geneA gene that makes one of the three subunits of a protein involved in cell growth, cell movement, and cell...
• LAMC2 geneA gene that makes one of the three subunits of a protein involved in cell growth, cell movement, and cell...
• lamellar body mimetic mouth spray LMS-611A suspension-based oral spray containing multilamellar lipid vesicles in which the lipids mimic the lipidic...
• lamina propriaA type of connective tissue found under the thin layer of tissues covering a mucous membrane.
• lamivudineA drug used to treat infection caused by viruses.
• lamotrigineA drug that is used to help control some types of seizures. It is being studied in the prevention of...
• landogrozumabA monoclonal antibody against myostatin (MSTN) with potential anti-cachexia activity. Upon administration...
• Langerhans cell histiocytosisA group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain...
• lanolinAn oily substance taken from sheep's wool. Lanolin is used in moisturizing creams and lotions to treat dry...
• LanoxinA drug used to treat irregular heartbeat and some types of heart failure. It is also being studied in the...
• lanraplenibAn orally available inhibitor of spleen tyrosine kinase (Syk), with potential immunomodulating and...
• lanreotide acetateA drug that is similar to somatostatin (a hormone made by the body) and is used to treat certain types of...
• lanreotide acetate copolymer microparticlesA prolonged-release depot suspension of microparticles containing the acetate salt of lanreotide, a synthetic...
• lanreotide long-acting aqueous gelA long-acting aqueous gel preparation of lanreotide, a synthetic cyclic octapeptide analogue of somatostatin...
• lansoprazoleA drug that reduces the amount of acid made in the stomach. It is used to treat stomach ulcers...
• LantusA drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the...
• laparoscopeA thin, tube-like instrument used to look at tissues and organs inside the abdomen. A laparoscope has a light...
• laparoscopic surgerySurgery done with the aid of a laparoscope. A laparoscope is a thin, tube-like instrument with a light and a...
• laparoscopic-assisted colectomySurgery done with the aid of a laparoscope to remove all or part of the colon through several small incisions...
• laparoscopic-assisted resectionSurgery done with the aid of a laparoscope. A laparoscope is a thin, tube-like instrument with a light and a...
• laparoscopyA procedure that uses a laparoscope, inserted through the abdominal wall, to examine the inside of the...
• laparotomyA surgical incision made in the wall of the abdomen.
• lapatinib ditosylateA drug used with capecitabine or letrozole to treat certain types of HER2-positive breast cancer that are...
• lapatinib/letrozole regimenA regimen consisting of lapatinib and letrozole that is used as a treatment for breast cancer.
• lappaA plant whose seeds and root have been used in some cultures to treat certain medical problems. It may have...
• lapuleucel-TA cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor...
• large cell carcinomaLung cancer in which the cells are large and look abnormal when viewed under a microscope.
• large granular lymphocyteA type of white blood cell that contains granules with enzymes that can kill tumor cells or microbial cells.
• large intestineThe long, tube-like organ that is connected to the small intestine at one end and the anus at the other. The...
• largetrifoliolious bugbane rhizome supplementA proprietary tablet formulation containing an extract from Largetrifoliolious Bugbane rhizome (Shengma), the...
• L-arginineOne of the twenty common amino acids (building blocks of proteins). L-arginine is being studied as a...
• L-arginine/Korean ginseng/ Gingko biloba/damiana-based supplementAn amino acid and herbal supplement with libido-enhancing activity. L-arginine/korean ginseng/Ginkgo...
• laromustineA drug used to treat acute myelogenous leukemia (AML). It is also being studied in the treatment of several...
• larotaxelA semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities...
• larotinib mesylateThe mesylate salt form of larotinib, a reversible pan-ErbB inhibitor with potential antineoplastic activity...
• larotrectinib sulfateA drug used to treat adults and children with certain types of solid tumors that have spread or cannot be...
• lartesertibAn orally bioavailable ATP-competitive inhibitor of ataxia telangiectasia mutated kinase (ATM), with...
• laryngealHaving to do with the larynx.
• laryngeal cancerCancer that forms in tissues of the larynx. The larynx is the area of the throat that contains the vocal...
• laryngectomeeA person whose larynx (voice box) has been removed.
• laryngectomyAn operation to remove all or part of the larynx (voice box).
• laryngitisInflammation of the larynx.
• laryngopharyngectomySurgery to remove all or part of the larynx (voice box) and pharynx (throat). Part of the esophagus and all...
• laryngoscopeA thin, tube-like instrument used to examine the larynx (voice box). A laryngoscope has a light and a lens...
• laryngoscopyExamination of the larynx (voice box) with a mirror (indirect laryngoscopy) or with a laryngoscope (direct...
• larynxThe area of the throat containing the vocal cords and used for breathing, swallowing, and talking. Also...
• laserA device that forms light into intense, narrow beams that may be used to cut or destroy tissue, such as...
• laser acupunctureThe use of a low-level laser beam instead of an acupuncture needle to stimulate an acupuncture point.
• laser interstitial thermal therapyA type of treatment that uses heat created by a laser beam to remove or destroy abnormal tissue, such as...
• laser surgeryA surgical procedure that uses the cutting power of a laser beam to make bloodless cuts in tissue or to...
• laser therapyTreatment that uses intense, narrow beams of light to cut and destroy tissue, such as cancer tissue. Laser...
• lasmotinibAn orally bioavailable inhibitor of checkpoint kinase 2 (chk2), with potential antineoplastic and...
• lasofoxifeneA non-steroidal, naphthalene-derived, third-generation selective estrogen receptor modulator (SERM) with...
• L-asparaginaseA drug that is used to treat acute lymphoblastic leukemia (ALL) and is being studied in the treatment of some...
• lassitudeA feeling of tiredness, weakness, and lack of interest in daily activities.
• late effectA health problem that occurs months or years after a disease is diagnosed or after treatment has ended. Late...
• late or variable onsetRefers to the age at which a disease phenotype is expressed in an individual who carries a pathogenic...
• latency periodThe time that passes between being exposed to something that can cause disease (such as radiation or a virus)...
• latentDescribes a condition that is present but not active or causing symptoms.
• late-stage cancerA term used to describe cancer that is far along in its growth, and has spread to the lymph nodes or other...
• LatisseThe drug bimatoprost used to increase the length, thickness, and darkness of eyelashes. It is being studied...
• latissimus dorsi flapA type of surgery used to rebuild the shape of the breast after a mastectomy. A muscle in the back called the...
• laughter therapyA type of therapy that uses humor to help relieve pain and stress and improve a person’s sense of well-being...
• lavageIn medicine, washing out an organ (such as the stomach or colon), a body cavity, or a wound by flushing it...
• lavenderA plant with aromatic leaves and flowers that is a member of the mint family. Oil from the flowers has been...
• lavender oilThe essential oil extracted from the flowers of several species of Lavandula. Lavender oil is used primarily...
• laventatug tivedotinAn antibody-drug conjugate (ADC) composed of laventatug, a humanized monoclonal antibody directed against...
• laxativeA substance that promotes bowel movements.
• LazcluzeA drug used with amivantamab to treat adults with non-small cell lung cancer that has spread to other parts...
• lazertinib mesylate hydrateA drug used with amivantamab to treat adults with non-small cell lung cancer that has spread to other parts...
• L-carnitineA form of carnitine, which is a substance made in muscle and liver tissue and found in certain foods, such as...
• L-carnitine L-tartrateA dietary supplement containing the levo-enantiomers of carnitine and tartrate with potential chemoprotective...
• LCHA group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain...
• LCISA condition in which abnormal cells are found in the lobules of the breast. This condition seldom becomes...
• LC-MSA laboratory technique that combines two different processes to separate, identify, and measure the amount of...
• LDWhere alleles (DNA markers) occur together more often than can be accounted for by chance because of their...
• LDCTA procedure that uses a computer linked to an x-ray machine that gives off a very low dose of radiation to...
• LDE225A drug used to treat locally advanced basal cell carcinoma (BCC) that has come back after surgery or...
• LDHOne of a group of enzymes found in the blood and other body tissues, and involved in energy production in...
• lead compoundIn medicine, a chemical compound that shows promise as a treatment for a disease and may lead to the...
• lead Pb 203 VMT-a-NETA radioconjugate consisting of the human somatostatin receptor subtype 2 (SSTR2)-targeting peptide and...
• lead Pb 203-VMT01A radioconjugate composed of the melanocyte-stimulating hormone receptor (MSHR; melanocortin-1 receptor...
• lead Pb 212 DOTAMTATEA radioconjugate consisting of the tyrosine-containing somatostatin analog Tyr3-octreotate (TATE) conjugated...
• lead Pb 212 pentixatherA radioconjugate composed of pentixather, a chemokine receptor C-X-C chemokine receptor type 4...
• lead Pb 212 TCMC-trastuzumabA radioimmunoconjugate containing the recombinant humanized monoclonal antibody trastuzumab conjugated with...
• lead Pb 212-DOTAM-GRPR1A radioconjugate consisting of a gastrin-releasing peptide receptor (GRPR)-targeting antagonist conjugated...
• lead Pb 212-VMT01A radioconjugate composed of the melanocyte-stimulating hormone receptor (MSHR; melanocortin-1 receptor...
• lead shieldIn medicine, a protective shield that may be placed on the outside of the body during radiation therapy or...
• lebrikizumabA humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic...
• lectinA complex molecule that has both protein and sugars. Lectins are able to bind to the outside of a cell and...
• LED therapyTreatment with drugs that become active and may kill cancer cells when exposed to light. LED therapy is a...
• ledipasvirAn orally available inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) replication...
• ledipasvir mixture with sofosbuvirA tablet containing a fixed dose combination of ledipasvir, an inhibitor of the hepatitis C virus (HCV)...
• LEEPA technique that uses electric current passed through a thin wire loop to remove abnormal tissue. Also called...
• leflunomideAn anticancer drug that works by inhibiting a cancer cell growth factor. Also called SU101.
• legal aid organizationA group or agency that gives legal help to some people with low incomes. Health legal aid organizations help...
• Legius syndromeA rare genetic condition marked by flat brown spots on the skin. The number of brown spots on the skin tends...
• leiomyomaA benign smooth muscle tumor, usually in the uterus or gastrointestinal tract. Also called fibroid.
• leiomyosarcomaA malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most...
• lemonA small, yellow citrus fruit that is a source of citric acid and ascorbic acid (vitamin C). The juice is used...
• lemzoparlimabA human monoclonal antibody targeting the human cell surface antigen CD47, with potential...
• lenalidomideA drug that is similar to thalidomide and is used alone or with other drugs to treat adults with certain...
• lenalidomide analog KPG-121A lenalidomide analog with potential anti-angiogenic and immunomodulatory activities. Upon oral...
• lenalidomide prolonged-release formulation NEX-20AA prolonged-release formulation composed of a suspension of the thalidomide analog lenalidomide coated with...
• lenapenemA broad-spectrum, carbapenem antibiotic with bactericidal activity. Lenapenem binds to penicillin binding...
• lenograstimA glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an...
• lensA clear disk that focuses light, as in a camera or microscope. In the eye, the lens is a clear, curved...
• Lenti-D/ABCD1-transduced autologous hematopoietic stem cellsAutologous CD34+ hematopoietic stem cells transduced with Lenti-D lentiviral vector encoding the human...
• LentiGlobin BB305 lentiviral vector-transduced autologous SCD CD34+ hemaptopoietic stem cells bb1111A preparation of autologous, CD34-positive hematopoietic stem cells (HSCs), obtained from patients with...
• lentinanA beta-glucan (a type of polysaccharide) from the mushroom Lentinus edodes (shiitake mushroom). It has been...
• lentivirus vector CCR5 shRNA/TRIM5alpha/TAR decoy-transduced autologous CD34-positive hematopoietic progenitor cellsAutologous, CD34-positive hematopoietic progenitor cells (HPCs) transduced with a lentiviral vector encoding...
• lentivirus vector rHIV7-shI-TAR-CCR5RZ-transduced hematopoietic progenitor cellsAutologous, CD34-positive hematopoietic progenitor cells (HPCs) transduced with rHIV7-shI-TAR-CCR5RZ, a...
• lenumlostatAn orally available, small-molecule, irreversible inhibitor of lysyl oxidase homolog 2 (lysyl oxidase-like...
• lenvatinib mesylateA drug used alone or with other drugs to treat certain types of endometrial cancer, renal cell carcinoma (a...
• LenvimaA drug used alone or with other drugs to treat certain types of endometrial cancer, renal cell carcinoma (a...
• lenzilumabA recombinant monoclonal antibody against the cytokine granulocyte macrophage colony-stimulating factor...
• LEP-ETUA form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have...
• lepirudinA drug that inhibits blood clotting. It is being studied in cancer treatment.
• leptinA hormone made by fat cells that helps control the feeling of hunger, the amount of fat stored in the body...
• leptomeningealHaving to do with the two innermost meninges (thin layers of tissue that cover and protect the brain and...
• leptomeningeal carcinomaA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• leptomeningeal carcinomatosisA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• leptomeningeal metastasisA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• lerapolturevA recombinant, live attenuated, nonpathogenic oncolytic virus containing the oral poliovirus Sabin type 1 in...
• leridistimA substance being studied for its ability to stimulate the production of blood cells during chemotherapy. It...
• leriglitazoneAn orally bioavailable, blood-brain-barrier (BBB) penetrable, selective peroxisome proliferator-activated...
• lerisetronThe hydrochloride salt of a 2-piperazinylbenzimidazole-derivative serotonin type 3 (5-HT3) receptor...
• lerociclibAn orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential...
• leronlimabA humanized immunoglobulin (Ig) G4 monoclonal antibody against CC chemokine receptor 5 (CCR5; CD195), with...
• lesionAn area of abnormal or damaged tissue caused by injury, infection, or disease. A lesion can occur anywhere in...
• lestaurtinibA drug being studied in the treatment of acute leukemias and some other types of cancer. It binds to a...
• letermovirAn orally bioavailable, non-nucleoside, 3,4-dihydroquinazolinyl acetic acid and inhibitor of the pUL56...
• letetresgene autoleucelHuman autologous T lymphocytes transduced with a lentiviral vector encoding a T-cell receptor (TCR) specific...
• lethargyA condition marked by drowsiness and an unusual lack of energy and mental alertness. It can be caused by many...
• letrozoleA drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the...
• letrozole/palbociclib regimenA regimen consisting of letrozole and palbociclib that can be used in the treatment of breast cancer.
• [Leu15] gastrin-17A C-terminal amidated synthetic gastrin analog with a single amino acid change at position 15, where leucine...
• leucine-enhanced essential amino acid dietary supplementAn orally bioavailable leucine enriched essential amino acid dietary supplement with potential anti-cachexia...
• leucovorin calciumA form of folic acid used alone or with other drugs to treat certain types of colorectal cancer and anemia...
• leukapheresisRemoval of the blood to collect specific blood cells. The remaining blood is returned to the body.
• leukemiaCancer that starts in blood-forming tissue, such as the bone marrow, and causes large numbers of abnormal...
• leukemia cellAn abnormal type of white blood cell that builds up in the bone marrow and blood of patients with leukemia...
• leukemic apoptotic corpse-pulsed autologous dendritic cellsA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic...
• leukemic leptomeningitisA serious problem that may occur in leukemia. In leukemic leptomeningitis, cancer cells have spread from the...
• leukemic meningitisA serious problem that may occur in leukemia. In leukemic meningitis, cancer cells have spread from the...
• LeukeranA drug used to treat chronic lymphocytic leukemia, Hodgkin lymphoma, and certain types of non-Hodgkin...
• leukocyteA type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. Leukocytes are...
• leukopeniaA condition in which there is a lower-than-normal number of leukocytes (white blood cells) in the blood.
• leukoplakiaAn abnormal patch of white or gray tissue that usually forms on the inside of the mouth, especially on the...
• leuprolide acetateA drug used under the brand names Eligard and Lupron Depot to treat prostate cancer and under the brand name...
• leuprolide acetate for injectable suspension TOL2506A subcutaneous injectable suspension formulation containing the acetate salt form of leuprolide, a synthetic...
• leuprolide acetate sustained-release microspheres PT105A sustained-release (SR) injectable microsphere formulation composed of the acetate salt of leuprolide, a...
• leuprolide mesylateA drug used to treat adults with advanced prostate cancer. Leuprolide mesylate initially causes the pituitary...
• leuvectinAn agent that delivers the gene for interleukin-2 (IL-2) into cells to increase production of IL-2 by the...
• levamisoleAn antiparasitic drug that is also being studied in cancer therapy with fluorouracil.
• levamisole hydrochlorideThe orally bioavailable hydrochloride salt of the synthetic imidazothiazole derivative levamisole with...
• levels of evidenceA ranking system used to describe the strength of the results measured in a clinical trial or research study...
• levetiracetamA drug used to treat seizures (involuntary muscle movements) caused by epilepsy (a group of brain disorders)...
• levobupivacaine hydrochlorideThe hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine...
• levocarnitineA form of carnitine, which is a substance made in muscle and liver tissue and found in certain foods, such as...
• levocetirizine dihydrochlorideThe dihydrochloride salt form of the active levorotatory enantiomer of cetirizine, levocetirizine; a third...
• levodopaAn amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted...
• levofloxacinA substance used to treat bacterial infections. It belongs to the family of drugs called quinolone...
• levoketoconazoleAn orally available levorotary enantiomer of ketoconazole with potential steroidogenesis inhibitory activity...
• levoleucovorin calciumA drug used to lessen the toxic effects of the anticancer drug methotrexate or other substances that block...
• levonantradolA synthetic cannabinoid analogue of delta (9)-tetrahydrocannabinol (delta(9)-THC) with antiemetic and...
• levonorgestrelA form of the hormone progesterone that is made in the laboratory and used to prevent pregnancy. It is being...
• levonorgestrel-releasing intrauterine systemA long-acting, hormone-releasing, intrauterine device consisting of a small, T-shaped, polyethylene frame and...
• levothyroxine sodiumThe sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous...
• Levulan KerastickA drug that contains the active ingredient aminolevulinic acid hydrochloride and is used with photodynamic...
• LexaproA drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called...
• lexaptepid pegolA proprietary 44-nucleotide L-stereoisomer RNA oligonucleotide conjugated to a 40 kDa polyethylene glycol...
• lexatumumabA substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL-R2 on...
• lexibulinAn orally bioavailable small-molecule with tubulin-inhibiting, vascular-disrupting, and potential...
• Leydig cell tumorA rare tumor that usually forms in the testicles. It may also form in the ovaries, but this is very rare...
• LFSA rare, inherited disorder that is caused by mutations (changes) in the TP53 gene. Having Li-Fraumeni...
• LGD1069A drug used to treat skin problems caused by cutaneous T-cell lymphoma that did not get better after other...
• L-glutamic acidOne of twenty amino acids (molecules that join together to form proteins). L-glutamic acid may help nerve...
• L-gossypolThe levo-enantiomer of an orally bioavailable polyphenolic aldehyde, derived primarily from unrefined...
• LHA hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their...
• Lhermitte's signA sensation similar to an electrical shock radiating from the back of the head down the spine as the neck is...
• LH-RHA hormone made by a part of the brain called the hypothalamus. LH-RH causes the pituitary gland in the brain...
• LHRHA hormone made by a part of the brain called the hypothalamus. LHRH causes the pituitary gland in the brain...
• LHRH agonistA substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are...
• LHRH antagonistA substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH)...
• liarozoleAn anticancer drug that promotes differentiation by increasing the levels of retinoic acid within the tumor.
• liarozole fumarateThe orally active fumarate salt of the benzimidazole derivative liarozole with potential antineoplastic...
• libidoSexual desire or the mental energy or emotion related to sex.
• LibtayoA drug that binds to the protein PD-1 to help immune cells kill cancer cells better and is used to treat...
• licartinAn immunoradioconjugate containing metuximab, an antibody fragment targeting the hepatocellular cancer...
• licochalcone AA derivative of the phenol chalconoid, found in and extracted from the roots of Glycyrrhiza species G. glabra...
• licogliflozinAn inhibitor of the sodium-dependent glucose co-transporter (sodium-glucose transporter; sodium-glucose...
• licoriceAn herbal extract derived from the root of the plant Glycyrrhiza glabra with potential anti-inflammatory...
• licorice root extractA substance prepared from dried roots of the plant Glycyrrhiza glabra. It is used as a flavoring in...
• lidocaineA substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given...
• lidocaine hydrochlorideThe hydrochloride salt form of lidocaine, an aminoethylamide and a prototypical member of the amide class...
• lidocaine hydrochloride ophthalmic gelAn ophthalmic gel formulation containing the synthetic amide-type anesthetic lidocaine, with potential...
• lidocaine mixture with tribenosideA formulation composed of the local anesthetic lidocaine and the vasoprotective agent tribenoside that can be...
• lidocaine patch 5%A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic...
• lidocaine topicalA synthetic aminoethylamide with local anesthetic activity applied topically to either the skin or mucous...
• lifestyle risk factorPersonal behaviors or choices that can increase a person’s chance of developing a disease. Lifestyle risk...
• lifetime riskA measure of the risk that a certain event will happen during a person’s lifetime. In cancer research, it is...
• lifileucelA treatment used for adults with melanoma that has spread to other parts of the body or cannot be removed by...
• Li-Fraumeni syndromeA rare, inherited disorder that is caused by mutations (changes) in the TP53 gene. Having Li-Fraumeni...
• ligand directed degrader BMS-986460A ligand directed degrader (LDD) composed of an E3 ubiquitin ligase-binding moiety that is conjugated, via a...
• ligationThe process of tying off blood vessels so that blood cannot flow to a part of the body or to a tumor.
• light cigaretteA type of cigarette that is claimed to give off less tobacco tar than a regular cigarette when smoked. Light...
• light microscopeA microscope (device to magnify small objects) in which objects are lit directly by white light.
• light therapyThe treatment of disease with certain types of light. Light therapy can use lasers, LED, fluorescent lamps...
• light-emitting diode therapyTreatment with drugs that become active and may kill cancer cells when exposed to light. Light-emitting diode...
• lignanA member of a group of substances found in plants that have shown estrogenic and anticancer effects. Lignans...
• lignin-derived polyphenolic composition with ammonium molybdate BP-C2An orally bioavailable solution containing lignin-derived benzene-polycarboxylic acids mixed with ammonium...
• ligufalimabA humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47, with...
• lilotomabA murine immunoglobulin G1 (IgG1) monoclonal antibody directed against the CD37 antigen with potential...
• limb perfusionA procedure that may be used to deliver anticancer drugs directly to an arm or leg. The flow of blood to and...
• limbic systemA network of structures in the brain involved in memory and emotions.
• limb-salvage surgerySurgery to remove a tumor in a limb (arm or leg) without removing the whole limb. The bone and tissue around...
• limb-sparing surgerySurgery to remove a tumor in a limb (arm or leg) without removing the whole limb. The bone and tissue around...
• limited-stage small cell lung cancerCancer is found in one lung, the tissues between the lungs, and nearby lymph nodes only.
• limonene, (+)-An oral dietary supplement containing a natural cyclic monoterpene, and a major component of the oil...
• LINA condition in which abnormal cells are found in the lobules (glands that make milk) of the breast. This...
• linacA machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy...
• linaclotide acetateThe acetate salt form of linaclotide, a synthetic, fourteen amino acid peptide and agonist of intestinal...
• linagliptinA potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with...
• Lindera obtusiloba extractA dietary supplement composed of an ethanol extracted powder of Lindera obtusiloba, with potential...
• linear acceleratorA machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy...
• linezolidA synthetic oxazolidinone derivative, linezolid selectively inhibits an early step in bacterial protein...
• linifanibAn orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic...
• linitis plasticaA rare type of stomach cancer that begins in the lining of the stomach and spreads to the muscles of the...
• linkageThe tendency for genes or other segments of DNA to be inherited together during meiosis because of their...
• linkage analysisA gene-hunting technique that traces patterns of disease in high-risk families. Linkage analysis attempts to...
• linkage disequilibriumWhere alleles (DNA markers) occur together more often than can be accounted for by chance because of their...
• linoleyl carbonate-paclitaxelA formulation of the 6-omega fatty acid derivative 2’-linoleyl carbonate (LOC) conjugated to paclitaxel, a...
• linperlisibAn orally available selective inhibitor of the delta form of phosphatidylinositol 3-kinase (PI3-kinase...
• linrodostatAn orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and...
• linseedThe seed of the flax plant. It is a rich source of omega-3 fatty acid, fiber, and a compound called lignin...
• linsitinibAn orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with...
• lintuzumabA substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds...
• linvoseltamabA human, immunoglobulin G4 (IgG4) bispecific antibody directed against the tumor-associated antigen (TAA)...
• linzagolixAn orally bioavailable gonadotropin-releasing hormone (GnRH or LHRH) receptor antagonist, with potential...
• LioresalA drug that is used to treat certain types of muscle spasms and is being studied in the treatment of liver...
• liothyronine sodiumA drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also...
• lipegfilgrastimA long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with...
• lipidFat.
• Lipid Nanoparticle Encapsulated mRNA Encoding Human Single-chain IL-12 ABO2011A formulation consisting of lipid nanoparticle (LNP)-encapsulated messenger RNA (mRNA) encoding human...
• lipid nanoparticle encapsulated mRNAs encoding human IL-12A/IL-12B MEDI-1191A formulation consisting of lipid nanoparticle encapsulated messenger RNA (mRNA) encoding human...
• lipid nanoparticle encapsulated MYC-targeting mRNA-based agent OTX-2002A lipid nanoparticle (LNP)-based formulation consisting of a biscistronic mRNA that encodes two independent...
• lipid nanoparticle encapsulated self-replicating RNA encoding human IL-12 JCXH-211A formulation consisting of lipid nanoparticle (LNP) encapsulating self-replicating RNA (srRNA) encoding...
• lipid nanoparticle encapsulated self-replicating RNA encoding human IL-12 STX-001A formulation consisting of lipid nanoparticle (LNP) encapsulating self-replicating RNA (srRNA) encoding...
• lipid nanoparticle encapsulating glutathione S-transferase P siRNA NBF-006A biodegradable, lyophilized lipid nanoparticle (LNP) encapsulating small interfering ribonucleic acid...
• lipid nanoparticle encapsulating hAQP1 circular RNA RXRG001A formulation consisting of lipid nanoparticles (LNPs) encapsulating circular RNA (circRNA) encoding human...
• lipid nanoparticle encapsulating mRNA encoding Cas9 protein and TTR-targeting single guide RNA NTLA-2001A lipid nanoparticle (LNP) formulation encapsulating messenger RNA (mRNA) encoding the clustered regularly...
• lipid nanoparticle encapsulating mRNAs encoding human OX40L/IL-23/IL-36gamma mRNA-2752A lipid nanoparticle encapsulating mRNAs encoding for the human co-stimulatory protein tumor necrosis factor...
• lipid nanoparticle-encapsulated EBV mRNA vaccine mRNA-1189A vaccine consisting of a lipid nanoparticle (LNP) encapsulating four messenger RNAs (mRNAs) encoding the...
• lipid nanoparticle-encapsulated OX40L mRNA-2416A proprietary formulation consisting of a lipid nanoparticle encapsulating a synthetic messenger RNA (mRNA)...
• lipid-encapsulated anti-PLK1 siRNA TKM-PLK1Short interfering RNAs (siRNAs) directed against polo-like kinase 1 (PLK1, STPK13), with potential...
• LipiodolA form of poppy seed oil that contains iodine. Lipiodol is given by injection and builds up in the blood and...
• LipitorA drug used to lower the amount of cholesterol in the blood and to prevent stroke, heart attack, and angina...
• lipomaA benign (not cancer) tumor made of fat cells.
• lipophilicAble to dissolve, be dissolved in, or absorb lipids (fats).
• lipopolysaccharideAn endotoxin and biologically active component of the Gram-negative bacterial cell wall that is a Toll-like...
• liposarcomaA rare type of cancer that begins in fat cells. It usually forms in the layer of fat just under the skin or...
• liposomalA drug preparation that contains the active drug inside very tiny, fat-like particles. This form is easier...
• liposomal alpha galactosylceramideA liposomal formulation of alpha galactosylceramide, a synthetic glycolipid isolated from the Okinawan marine...
• liposomal amphotericin BA liposome-encapsulated formulation of the polyene antifungal antibiotic amphotericin B produced by the...
• liposomal Bcl-2 antisense oligonucleotide BP1002A liposomal-based nanoparticle composed of an uncharged P-ethoxy antisense oligodeoxynucleotide (ODN)...
• liposomal belotecanA sterically stabilized, pegylated liposomal formulation containing CKD602, a semi-synthetic analogue of...
• liposomal Chk1 inhibitor SMP-3124 SMP-3124LPA liposomal formulation containing an inhibitor of checkpoint kinase 1 (chk1), with potential antineoplastic...
• liposomal CMTR2 inhibitor AT-1965A liposomal formulation containing an inhibitor of cap-specific mRNA (nucleoside-2-O-)-methyltransferase 2...
• liposomal c-raf antisense oligonucleotideThe liposomal formulation of a c-raf-1 antisense oligonucleotide, with potential antineoplastic activity...
• liposomal curcuminA liposomal formulation containing curcumin, a poorly water-soluble polylphenol pigment isolated from the...
• liposomal daunorubicin citrateA liposome-encapsulated form of the citrate salt of the anthracycline antineoplastic antibiotic daunorubicin...
• liposomal docetaxelA formulation of the poorly soluble, semi-synthetic, second-generation taxane docetaxel encapsulated within...
• liposomal doxorubicin hydrochlorideA form of the anticancer drug doxorubicin that is contained inside very tiny, fat-like particles and is used...
• liposomal eribulin mesylateA liposome-encapsulated formulation of the mesylate salt form of eribulin, a synthetic, macrocyclic ketone...
• liposomal HPV-16 E6/E7 multipeptide vaccine PDS0101A liposomal nanoparticle-based therapeutic vaccine composed of the cationic lipid R-DOTAP (R-enantiomer of...
• liposomal interleukin-2A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T...
• liposomal lurtotecanA liposome-encapsulated formulation of lurtotecan with antineoplastic activity. Lurtotecan, a semisynthetic...
• liposomal mitoxantrone hydrochlorideA formulation composed of the hydrochloride salt form of the anthracenedione antibiotic mitoxantrone...
• liposomal MUC1/PET-lipid A vaccineA cancer vaccine comprised of a 43 amino acid epitope from glycoprotein MUC1 (mucin 1) and the synthetic...
• liposomal NDDPA synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation...
• liposomal oxaliplatinA liposomal formulation of the prodrug oxaliplatin, an organoplatinum complex in which the platinum atom is...
• liposomal paclitaxelA form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have...
• liposomal rhenium Re 186A therapeutic preparation consisting of the beta-emitting radioisotope rhenium Re 186 encapsulated in a...
• liposomal SN-38A form of the anticancer drug irinotecan that is contained in very tiny, fat-like particles. It may have...
• liposomal T4N5 lotionA topical lotion that contains the enzyme T4-bacteriophage endonuclease V encapsulated within liposomes. With...
• liposomal topotecan FF-10850A liposome encapsulated formulation of the semisynthetic camptothecin analogue topotecan with potential...
• liposomal topotecan hydrochlorideThe hydrochloride salt of a semisynthetic derivative of camptothecin mixed with sphingomyelin/cholesterol and...
• liposomal tretinoinAn intravenous formulation of tretinoin (vitamin A acid or all-trans retinoic acid) encased in liposomes...
• liposomal vinorelbineA formulation of the semisynthetic vinca alkaloid, vinorelbine, encapsulated within liposomes, with...
• liposomal vinorelbine tartrateA formulation of the tartrate salt form of vinorelbine, a semisynthetic vinca alkaloid, encapsulated within...
• liposomeA very tiny, fat-like particle that is made in the laboratory. In medicine, liposomes containing drugs or...
• liposome-encapsulated daunorubicin-cytarabineA liposomal formulation containing a fixed combination of the antineoplastic agents cytarabine and...
• liposome-encapsulated doxorubicin citrateA formulation of the citrate salt of the antineoplastic anthracycline antibiotic doxorubicin, encapsulated...
• liposome-encapsulated miR-34 mimic MRX34A liposomal formulation containing a nucleotide that mimics the human tumor suppressor microRNA (miRNA)...
• liposome-encapsulated RB94 plasmid DNA gene therapy agent SGT-94A systemic gene therapy anti-cancer agent composed of cationic liposomes, which encapsulates plasmid DNA...
• liposome-encapsulated recombinant human Cu/Zn superoxide-dismutaseA topical hydrophilic gel containing a recombinant form of the human Cu/Zn superoxide dismutase (SOD1), a...
• liposome-encapsulated TAAs mRNA vaccine W_ova1A vaccine consisting of messenger RNA (mRNA) encoding three tumor-associated antigens (TAAs) specific for...
• liposome-incorporated Grb2 antisense oligodeoxynucleotideA liposomal formulation containing the antisense oligodeoxynucleotide (ODN) growth factor receptor-bound...
• liposuctionA surgical procedure in which a vacuum device is used to remove extra fat from the body. Liposuction is...
• LipoTaxenA form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have...
• liquid biopsyA laboratory test done on a sample of blood, urine, or other body fluid to look for cancer cells from a tumor...
• liquid chromatography-mass spectrometryA laboratory technique that combines two different processes to separate, identify, and measure the amount of...
• liquid-based Pap testA type of Pap test. A Pap test is a procedure in which cells are scraped from the cervix for examination...
• liraglutideA long-acting, fatty acylated glucagon-like peptide-1 (GLP-1) analog administered subcutaneously, with...
• lirilumabA fully human monoclonal antibody against killer-cell immunoglobulin-like receptors (KIR), with potential...
• lisaftoclaxAn orally bioavailable and selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with...
• lisdexamfetamine dimesylateThe dimesylate form and prodrug of the d-isomer of amphetamine, a non-catecholamine sympathomimetic amine...
• lisinoprilA drug used to treat high blood pressure and certain heart conditions. It is also being studied in the...
• lisocabtagene maraleucelA treatment used for adults with chronic lymphocytic leukemia, small lymphocytic lymphoma, follicular...
• lisofyllineA drug that may protect healthy cells from chemotherapy and radiation without inhibiting the effects of these...
• Listeria monocytogenes-LLO-prostate cancer neoantigens vaccine ADXS-504An off-the-shelf (OTS) cancer vaccine containing a live-attenuated strain of the Gram-positive bacterium...
• Listeria monocytogenes-LLO-PSA vaccine ADXS31-142A cancer vaccine containing a live-attenuated strain of the Gram-positive bacterium Listeria monocytogenes...
• literA measure of volume for a liquid, using the metric system. One liter is equal to 1,000 cubic centimeters...
• lithiumA soft metal. Lithium salts are used to treat certain mental disorders, especially bipolar (manic depressive)...
• lithium carbonateThe carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium...
• litronesibAn inhibitor of the kinesin-related motor protein Eg5 with potential antineoplastic activity. Litronesib...
• LITTA type of treatment that uses heat created by a laser beam to remove or destroy abnormal tissue, such as...
• live attenuated measles virus vaccineA live, attenuated measles vaccine with potential antineoplastic activity. Upon subcutaneous administration...
• live freeze-dried lactic acid bacteria probioticA probiotic containing live, cultivated, freeze-dried lactic acid bacteria with gastrointestinal (GI)...
• live virus vaccineA vaccine made from a virus that has been weakened so it does not cause the disease the virus usually causes...
• live-attenuated double-deleted Listeria monocytogenes bacteria JNJ-64041809A proprietary, live-attenuated, double-deleted (LADD) strain of the Gram-positive bacterium Listeria...
• live-attenuated Listeria monocytogenes encoding EGFRvIII-NY-ESO-1 vaccine ADU-623A live-attenuated, double-deleted strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding...
• live-attenuated listeria-encoding human mesothelin vaccine CRS-207A recombinant Listeria-based cancer vaccine containing a live-attenuated strain of the facultative...
• liverA large organ located in the upper abdomen. The liver cleanses the blood and aids in digestion by secreting...
• liver and bile duct cancerPrimary liver cancer is cancer that forms in the tissues of the liver. The most common type of primary liver...
• liver cancerPrimary liver cancer is cancer that forms in the tissues of the liver. Secondary liver cancer is cancer that...
• liver cancer neoantigens-sensitized autoimmune cells IPM001A preparation of autoimmune cells that have been sensitized to liver cancer neoantigens, with potential...
• liver function testA blood test to measure the blood levels of certain substances released by the liver. A high or low level of...
• liver metastasisCancer that has spread from the original (primary) tumor to the liver.
• liver X receptor alpha pathwayDescribes a group of proteins in a cell that work together to help control how certain genes are expressed...
• liver-spleen scanA procedure used to check for abnormal areas in the liver or spleen. A very small amount of a radioactive...
• living willA type of advance directive that states the specific types of medical care that a person wishes to receive if...
• livmoniplimabA humanized monoclonal antibody directed against the transforming growth factor beta (TGFbeta) activator...
• lixumista acetateThe acetate salt form of lixumistat, an orally bioavailable biguanide compound and mitochondrial oxidative...
• L-leucyl-L-leucine methyl esterA 2-amino acid compound with immunomodulatory activity. L-leucyl-L-leucine methyl ester (LLME) is a...
• L-lysineA nutritional supplement containing the biologically active L-isomer of the essential amino acid lysine, with...
• L-lysine/L-arginine-containing amino acid solutionAn intravenous (IV) amino acid (AA) solution containing the cationic amino acids L-lysine and L-arginine...
• LMB-1 immunotoxinA toxic substance linked to an antibody that attaches to tumor cells and kills them.
• LMB-2 immunotoxinA toxic substance linked to an antibody that attaches to tumor cells and kills them.
• LMB-7 immunotoxinA toxic substance linked to an antibody that attaches to tumor cells and kills them.
• LMB-9 immunotoxinA toxic substance linked to an antibody that attaches to tumor cells and kills them.
• LmddA-LLO-chHER2 fusion protein-secreting live-attenuated Listeria cancer vaccine ADXS31-164A cancer vaccine containing a live, highly attenuated strain of the Gram-positive bacterium Listeria...
• L-menthol preparation NPO-11A preparation containing L-menthol with potential anti-peristaltic activity. Upon spraying directly onto the...
• L-methylfolateA nutritional supplement containing the biologically active form of the B9 vitamin folate...
• LMP1-specific chimeric antigen receptor-expressing T lymphocytesA preparation of cytotoxic T lymphocytes (CTL) transfected with a chimeric antigen receptor (CAR)...
• LMP-2:340-349 peptide vaccineA peptide cancer vaccine containing amino acid residues 340-349 of the Epstein-Barr virus (EBV) latent...
• LMP-2:419-427 peptide vaccineA peptide cancer vaccine containing amino acid residues 419-427 of the latent membrane protein-2 (LMP-2) of...
• LMP2a-specific cytotoxic T-lymphocytesA preparation of cytotoxic T-lymphocytes (CTL), specifically reactive to Epstein-Barr virus (EBV) latent...
• LMP2-specific IL-12-secreting T cell receptor-transduced T lymphocytesA preparation of T lymphocytes that have been genetically modified to encode a T-cell receptor (TCR) specific...
• LMP2-specific T-cell receptor-transduced autologous T lymphocytesA preparation of autologous T lymphocytes that have been genetically modified to express a T-cell receptor...
• LMP400A substance being studied in the treatment of cancer. It blocks certain enzymes that break and rejoin DNA...
• LMP7 inhibitor M3258An orally bioavailable, potent, selective, reversible inhibitor of the large multifunctional peptidase 7...
• LMP776A substance being studied in the treatment of cancer. It blocks certain enzymes that break and rejoin DNA...
• LMP/BARF1/ EBNA1-specific cytotoxic T lymphocytesA preparation of allogeneic cytotoxic T-lymphocytes (CTL) made specifically reactive to three Epstein-Barr...
• Lm-tLLO-neoantigens vaccine ADXS-NEOA proprietary, personalized plasmid DNA-based cancer vaccine composed of a live-attenuated strain of the...
• L-MTP-PEA drug being studied in the treatment of young adults with bone cancer that has gotten worse or come back...
• L-norgestrelA form of the hormone progesterone that is made in the laboratory and used to prevent pregnancy. It is being...
• lobaplatinA substance that contains the metal platinum and may kill cancer cells by damaging their DNA and stopping...
• lobeA portion of an organ, such as the liver, lung, breast, thyroid, or brain.
• lobectomySurgery to remove a whole lobe (section) of an organ (such as the lungs, liver, brain, or thyroid gland).
• lobelineA substance that comes from a plant known as Indian tobacco, which is different from the tobacco used to make...
• lobradimilA substance that is being studied for its ability to help other drugs reach the brain. It belongs to the...
• lobular capillary hemangiomaA benign (not cancer) blood vessel tumor that usually forms on the skin. It may also form on mucous membranes...
• lobular carcinomaCancer that begins in the lobules (milk glands) of the breast. Lobular carcinoma may be either lobular...
• lobular carcinoma in situA condition in which abnormal cells are found in the lobules of the breast. This condition seldom becomes...
• lobular intraepithelial neoplasiaA condition in which abnormal cells are found in the lobules (glands that make milk) of the breast. This...
• lobular neoplasiaA condition in which abnormal cells are found in the lobules (glands that make milk) of the breast. This...
• lobuleA small lobe or a subdivision of a lobe.
• local anesthesiaA temporary loss of feeling in one small area of the body caused by special drugs called anesthetics. The...
• local therapyTreatment that is directed to a specific organ or limited area of the body, such as the breast or an abnormal...
• localizedIn medicine, describes disease that is limited to a certain part of the body. For example, localized cancer...
• localized cancerDescribes cancer that is found only in the tissue or organ where it first began and that has not spread to...
• localized gallbladder cancerCancer found only in the tissues that make up the wall of the gallbladder. Localized gallbladder cancer can...
• localized therapyTreatment that is directed to a specific organ or limited area of the body, such as the breast or an abnormal...
• locally advanced cancerCancer that has spread from where it started to nearby tissue or lymph nodes.
• locally recurrent cancerCancer that has recurred (come back) at or near the same place as the original (primary) tumor, usually after...
• locally-acting temozolomide formulation SI-053A powder for gel formulation containing the cytotoxic alkylating agent temozolomide (TMZ), an...
• locusSpecific place where something is located or occurs. It may refer to a specific place on the body (such as an...
• locus heterogeneityA term that describes when mutations (changes) in different genes cause the same disease or condition. Each...
• LOD scoreA statistical estimate of whether two genetic loci are physically near enough to each other (or "linked") on...
• lodapolimabA monoclonal antibody directed against programmed cell death-1 ligand 1 (PD-L1) with immune checkpoint...
• LofibraA drug used to treat high levels of cholesterol and triglycerides in the blood. Lofibra is being studied in...
• logarithm of the odds scoreA statistical estimate of whether two genetic loci are physically near enough to each other (or "linked") on...
• LOHIf there is one normal and one abnormal allele at a particular locus, as might be seen in an inherited...
• lometrexolA substance that is being studied as a treatment for cancer. It belongs to the family of drugs called...
• lomonitinibAn orally bioavailable inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2) mutations and...
• lomustineA drug used to treat brain tumors that have already been treated with surgery or radiation therapy and...
• lomvastomigA bispecific antibody directed against both the negative immunoregulatory human cell receptor programmed cell...
• lonafarnibAn anticancer drug that belongs to the family of drugs called enzyme inhibitors. Also called SCH 66336.
• lonaprisanAn orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic...
• loncastuximab tesirineA drug used to treat adults with certain types of B-cell non-Hodgkin lymphoma that relapsed (came back) or...
• loncastuximab tesirine-lpylAn antibody-drug conjugate (ADC) consisting of an anti-CD19 humanized monoclonal antibody conjugated, via a...
• long PD-L1 peptide vaccineA peptide cancer vaccine composed of a long peptide, containing amino acids 19 through 27...
• long peptide vaccine 7A peptide vaccine consisting of a combination of seven synthetic long peptides (SLPs), which are each about...
• long-acting recombinant Erwinia asparaginase JZP341A long-acting and recombinant form of asparaginase (Erwinia asparaginase; crisantaspase), with potential...
• long-acting release pasireotideA long-acting release (LAR) formulation containing pasireotide, a synthetic long-acting cyclohexapeptide...
• longitudinal cohort studyA type of research study that follows large groups of people over a long time. The groups are alike in many...
• long-term side effectA problem that is caused by a disease or treatment of a disease and may continue for months or years...
• LonsurfA combination of two drugs used alone or with bevacizumab to treat adults with certain types of colorectal...
• loop electrosurgical excision procedureA technique that uses electric current passed through a thin wire loop to remove abnormal tissue. Also called...
• loop excisionA technique that uses electric current passed through a thin wire loop to remove abnormal tissue. Also called...
• loperamide hydrochlorideA drug used to treat diarrhea. Loperamide hydrochloride works by binding to mu opioid receptors in the...
• lopinavirA drug used with another drug, called ritonavir, to treat infection with HIV (the virus that causes AIDS). It...
• lopinavir/ritonavirA combination of the drugs ritonavir and lopinavir. It is used to treat infection with HIV (the virus that...
• LoqtorziA drug used alone or with other drugs to treat adults with certain types of nasopharyngeal cancer (a type of...
• loratadineA piperidine histamine H1-receptor antagonist with anti-allergic properties and without sedative effects...
• lorazepamA drug that is used to treat anxiety and certain seizure disorders (such as epilepsy), and to prevent nausea...
• LorbrenaA drug used to treat adults with non-small cell lung cancer that has spread to other parts of the body and is...
• lorigerlimabA hinge stabilized immunoglobulin G4 (IgG4) tetravalent bispecific antibody-like protein directed against the...
• lorlatinibA drug used to treat adults with non-small cell lung cancer that has spread to other parts of the body and is...
• lorpucitinibAn orally bioavailable pan-inhibitor of the Janus associated-kinases (JAKs), with potential immunomodulatory...
• lorvotuzumab mertansineA substance being studied in the treatment of some types of cancer, including Wilms tumor, neuroblastoma...
• losartanA non-peptide angiotensin II antagonist with antihypertensive activity. Upon administration, losartan and its...
• losartan potassiumA drug used to treat high blood pressure. Losartan potassium blocks the action of chemicals that make blood...
• losoxantroneAn anticancer drug that belongs to the family of drugs called antipyrazoles.
• loss of heterozygosityIf there is one normal and one abnormal allele at a particular locus, as might be seen in an inherited...
• lovastatinA drug used to lower the amount of cholesterol in the blood. It is also being studied in the prevention and...
• low birth weightA term used to describe an infant born weighing 5.5 pounds (2500 grams) or less. A low birth weight may occur...
• low gradeA term used to describe cells and tissue that look almost normal under a microscope. Low-grade cancer cells...
• low tar cigaretteA type of cigarette that is claimed to give off less tobacco tar than a regular cigarette when smoked. Low...
• low-dose chemotherapyTreatment in which low doses of anticancer drugs are given on a continuous or frequent, regular schedule...
• low-dose computed tomographyA procedure that uses a computer linked to an x-ray machine that gives off a very low dose of radiation to...
• low-dose CT scanA procedure that uses a computer linked to an x-ray machine that gives off a very low dose of radiation to...
• low-dose radiation therapyRadiation treatment in which the total dose of radiation is less than that given in standard radiation...
• lower extremityThe part of the body that includes the leg, ankle, and foot.
• lower GI seriesX-rays of the colon and rectum that are taken after a person is given a barium enema.
• lower jaw boneThe lower jaw bone is the largest and strongest bone in the face. It forms the lower part of the jaw and part...
• low-grade DCISA condition in which cells that look mostly like normal cells under a microscope are found in the lining of a...
• low-grade ductal carcinoma in situA condition in which cells that look mostly like normal cells under a microscope are found in the lining of a...
• low-grade fibromyxoid sarcomaA rare, slow-growing type of cancer that usually forms in the deep soft tissues of the legs or trunk (chest...
• low-grade lymphomaA type of lymphoma that tends to grow and spread slowly, and has few symptoms. Also called indolent lymphoma.
• low-grade squamous intraepithelial lesionAn area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva...
• low-risk cancerCancer that tends to grow slowly, usually does not spread to other parts of the body, and may have a good...
• low-risk HPVA group of human papillomaviruses (HPV) that can infect cells on the moist surfaces or inner lining of some...
• low-risk human papillomavirusA group of human papillomaviruses (HPV) that can infect cells on the moist surfaces or inner lining of some...
• LOXO-101A drug used to treat adults and children with certain types of solid tumors that have spread or cannot be...
• LPA procedure in which a thin, hollow needle is inserted into the lower part of the spine to collect a sample...
• LPHLA rare type of Hodgkin lymphoma (a cancer of the immune system). It is marked by the presence of...
• LRMDA geneA gene that makes a protein involved in the formation of cells that make the pigment melanin, which gives...
• LRP-1-targeted peptide-drug conjugate GRN1005A peptide-drug conjugate containing the taxane paclitaxel covalently linked to the proprietary 19 amino acid...
• LRP5 antagonist BI 905681An antagonist of the lipoprotein receptor-related protein (LRP) 5, with potential antineoplastic and...
• LRP5/6 antagonist BI 905677A humanized biparatopic nanobody composed of two blocking domains for the Wnt ligand co-receptors lipoprotein...
• LSD1 inhibitor GSK2879552An orally available, irreversible, inhibitor of lysine specific demethylase 1 (LSD1), with potential...
• LSD1 inhibitor SYHA1807An orally available inhibitor of lysine-specific demethylase 1 (LSD1; KDM1A), with potential antineoplastic...
• LSD1 inhibitor TAS1440An orally available inhibitor of lysine-specific demethylase 1 (LSD1; KDM1A), with potential antineoplastic...
• LSD1/HDAC6 inhibitor JBI-802An orally bioavailable inhibitor of two proteins that are part of the corepressor to the silencer repressor...
• L-selenomethionineThe amino acid methionine with selenium substituting for the sulphur moiety. Methionine is an essential amino...
• LSILAn area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva...
• L-threo-dihydrosphingosineA substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• LU 79553An anticancer drug that kills cancer cells by affecting DNA synthesis.
• LU-103793An anticancer drug that reduces the risk of tumor cell growth and reproduction.
• lubiprostoneA bicyclic fatty acid derived from prostaglandin E1 and a chloride channel activator with laxative activity...

655 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.