Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: L (655)

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• lubricantAn oily or slippery substance.
• lucanthoneAn orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme...
• lucatumumabA monoclonal antibody directed against the B-cell surface antigen CD40 with potential antineoplastic...
• lucitanibA novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast...
• Lugol's solutionA solution composed of iodine and potassium iodide, which can be used as a reagent and antiseptic, with...
• LumakrasA drug used alone to treat adults with non-small cell lung cancer that has spread or cannot be removed by...
• lumbar punctureA procedure in which a thin, hollow needle is inserted into the lower part of the spine to collect a sample...
• LUMBAR/PELVIS/SACRAL syndromeA rare disorder marked by a hemangioma (a benign blood vessel tumor) that spreads across a large area of the...
• lumenThe cavity or channel within a tube or tubular organ such as a blood vessel or the intestine.
• LumiganThe drug bimatoprost used to treat glaucoma (a build-up of fluid in the eye). It lowers pressure in the eye...
• luminal A breast cancerA subtype of hormone receptor-positive breast cancer. Luminal A breast cancer cells typically have estrogen...
• luminal B breast cancerA subtype of hormone receptor-positive breast cancer. Luminal B breast cancer cells typically have estrogen...
• lumpectomySurgery to remove cancer or other abnormal tissue from the breast and some normal tissue around it, but not...
• lumretuzumabAn immunoconjugate containing a glycoengineered, humanized monoclonal antibody directed against the human...
• lumrotatugA monoclonal antibody directed against the human cell surface glycoprotein ADP-ribosyl cyclase 1 (CD38), with...
• lungOne of a pair of organs in the chest that supplies the body with oxygen, and removes carbon dioxide from the...
• lung biopsyThe removal of a small piece of lung tissue to be checked by a pathologist for cancer or other diseases. The...
• lung cancerCancer that forms in tissues of the lung, usually in the cells lining air passages. The two main types are...
• lung disorderA type of disease that affects the lungs and other parts of the respiratory system. Lung disorders may be...
• lung functionA term used to describe how well the lungs work in helping a person breathe. During breathing, oxygen is...
• lung function testA test used to measure how well the lungs work. It measures how much air the lungs can hold and how quickly...
• lung metastasisCancer that has spread from the original (primary) tumor to the lung.
• lung tumor-associated antigenA tumor-associated antigen derived from the cell surface antigen of lung cancer cells. Lung tumor-associated...
• lung-targeted immunomodulator QBKPNA proprietary, lung-targeted, site specific immunomodulator (SSI), with potential immunostimulating and...
• lunresertibAn orally bioavailable inhibitor of the human membrane-associated tyrosine- and threonine-specific...
• LunsumioA drug used to treat adults with follicular lymphoma that came back or did not get better after treatment...
• Lupron DepotA drug used under the brand names Eligard and Lupron Depot to treat prostate cancer and under the brand name...
• lupusA chronic, inflammatory, connective tissue disease that can affect the joints and many organs, including the...
• lurbinectedinA drug used to treat adults with small cell lung cancer that has spread to other parts of the body and got...
• lurtotecanAn anticancer drug that belongs to the family of drugs called topoisomerase inhibitors.
• luspaterceptA drug used to treat anemia in adults with certain types of myelodysplastic syndromes or...
• luspatercept-aamtA soluble, recombinant fusion protein composed of a modified form of the extracellular domain of human...
• LutatheraA radioactive drug used to treat adults and children aged 12 years and older with gastroenteropancreatic...
• luteinizing hormoneA hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their...
• luteinizing hormone-releasing hormoneA hormone made by a part of the brain called the hypothalamus. Luteinizing hormone-releasing hormone causes...
• luteinizing hormone-releasing hormone agonistA substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are...
• luteinizing hormone-releasing hormone antagonistA substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH)...
• luteolinA naturally-occurring flavonoid, with potential anti-oxidant, anti-inflammatory, apoptosis-inducing and...
• lutetium Lu 177 AB-3PRGD2A radiopharmaceutical agent comprised of a pegylated cyclic arginine-glycine-aspartic acid (RGD) dimer...
• lutetium Lu 177 anti-CA19-9 monoclonal antibody 5B1A radioimmunoconjugate comprised of a human monoclonal antibody (huMAb-5B1) against the carbohydrate antigen...
• lutetium Lu 177 anti-PD-L1 nanobody RAD204A radioimmunoconjugate composed of a nanobody directed against programmed cell death-1 ligand 1 (PD-L1...
• lutetium Lu 177 DOTA-biotinA radioconjugate of biotin conjugated with the bifunctional, macrocyclic chelating agent...
• lutetium Lu 177 DOTA-N3-CTT1403A radioconjucate consisting of CTT1403, a phosphoramidate-based irreversible inhibitor of human...
• lutetium Lu 177 DOTA-tetulomabA radioimmunoconjugate, which consists of a monoclonal antibody against the cell-surface antigen CD37...
• lutetium Lu 177 DPI-4452 Debio 0228A radioconjugate composed of the DOTA cyclic peptide DPI-4452, a carbonic anhydrase IX (CAIX; CA9)-targeting...
• lutetium Lu 177 EB-PSMA-617A radioconjugate composed of PSMA-617, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium Lu 177 FF58A radioconjugate composed of FF58, a non-arginine-glycine-aspartic acid (Arg-Gly-Asp/RGD) small molecule...
• lutetium Lu 177 LNC1004A radioconjugate consisting of an Evans blue (EB) modified fibroblast activation protein inhibitor (FAPi)...
• lutetium Lu 177 ludotadipepA radioconjugate composed of ludotadipep, a prostate-specific membrane antigen (PSMA)-targeting agent, linked...
• lutetium Lu 177 monoclonal antibody CC49A radioimmunoconjugate of the humanized monoclonal antibody (MoAb) CC49 labeled with lutetium 131 (Lu-177)...
• lutetium Lu 177 NYM032A radioconjugate composed of NYM032, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium Lu 177 PP-F11NA radioconjugate composed of PP-F11N, a gastrin analog, conjugated to the beta-emitting radioisotope lutetium...
• lutetium Lu 177 PSMA-10.1A radioconjugate composed of PSMA-10.1, a prostate-specific membrane antigen (PSMA)-targeting ligand and...
• lutetium Lu 177 PSMA-EB-01A radioconjugate composed of PSMA-EB-01, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium Lu 177 rsopatamab tetraxetanA radioimmunoconjugate consisting of rosopatamab, a humanized monoclonal antibody (MoAb) against the external...
• lutetium Lu 177 satoreotide tetraxetanA radioconjugate consisting of the somatostatin antagonistic peptide satoreotide tetraxetan (JR11) that is...
• lutetium Lu 177 vipivotide tetraxetanA radioactive drug used to treat adults with PSMA-positive prostate cancer that has spread to other parts of...
• lutetium Lu 177 XT117A radioconjugate composed of XT117, a fibroblast activation protein inhibitor (FAPi), conjugated to the...
• lutetium Lu 177-capromabA radioimmunoconjugate consisting of capromab linked to lutetium Lu 177 via the bifunctional macrocyclic...
• lutetium Lu 177-DOTAA radioconjugate composed of the chelating agent 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid...
• lutetium Lu 177-DOTA-ABM-5GA radioconjugate composed of 5G, an agent targeting an as of yet undisclosed target, conjugated, via the...
• lutetium Lu 177-DOTA-di-HSG peptide IMP-288A radiolabeled divalent histamine-succinyl-glycine (HSG) hapten-peptide linked with the macrocyclic chelator...
• lutetium Lu 177-DOTA-EB-TATEA radioconjugate consisting of Evans blue (EB) modified, tyrosine-containing somatostatin analog...
• lutetium Lu 177-DOTA-IPN01087A radioconjugate consisting of the neurotensin receptor type 1 (NTR1) antagonist, IPN01087 (3BP-227), that is...
• lutetium Lu 177-dotatateA radioactive drug used to treat adults and children aged 12 years and older with gastroenteropancreatic...
• lutetium Lu 177-DTPA-omburtamabA radioimmunoconjugate consisting of omburtamab, a murine immunoglobulin G1 (IgG1) antibody directed against...
• lutetium Lu 177-EB-LM3A radioconjugate composed of LM3, a human somatostatin receptor (SSTR) antagonist, conjugated to the...
• lutetium LU 177-edotreotideA radioconjugate consisting of the somatostatin analogue edotreotide labeled with lutetium Lu 177 with...
• lutetium Lu 177-NeoBA radioconjugate consisting of the gastrin-releasing peptide receptor (GRPR) antagonist, NeoB, linked via the...
• lutetium Lu 177-PSMA-I&TA radioconjugate composed of PSMA-I&T, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium Lu-177 girentuximabA radioimmunoconjugate consisting of the chimeric monoclonal antibody cG250 linked to the low energy...
• lutetium Lu-177 PNT2002A radioconjugate composed of PNT2002, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium Lu-177 PSMA-R2A radioconjugate composed of PSMA-R2, a human prostate-specific membrane antigen (PSMA)-targeting ligand...
• lutetium texaphyrinA substance that is being studied in the treatment of cancer using photodynamic therapy. It belongs to the...
• lutikizumabA dual-variable domain (DVD) immunoglobulin G1 kappa (IgG1k) against the inflammatory cytokine human...
• lutropinA hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their...
• luveltamab tazevibulinAn antibody drug conjugate (ADC) composed of SP8166 (H01), an anti-folate receptor alpha (FolRa; FOLR1) human...
• LuvoxA drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective...
• LVASurgery done to help relieve symptoms of lymphedema (swelling caused by a buildup of lymph in the tissues)...
• LVBSurgery done to help relieve symptoms of lymphedema (swelling caused by a buildup of lymph in the tissues)...
• LV.IL-2/B7.1-transduced AML blast vaccineA whole-cell cancer vaccine, containing human acute myeloid leukemic (AML) blasts that have been genetically...
• LXR alpha pathwayDescribes a group of proteins in a cell that work together to help control how certain genes are expressed...
• LY231514A drug used alone or with other drugs to treat certain types of non-small cell lung cancer and malignant...
• LY293111A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called...
• LY317615A substance being studied in the treatment of certain types of cancer, including non-Hodgkin lymphoma...
• LY335979A substance being studied in the treatment of cancer. LY335979 may help kill cancer cells that are resistant...
• LY353381 hydrochlorideA substance being studied in the treatment of osteoporosis and breast cancer. LY353381 hydrochloride is made...
• LY6K/VEGFR1/VEGFR2 multipeptide vaccineA multipeptide vaccine consisting of peptides derived from lymphocyte antigen 6 complex locus K (LY6K) and...
• lycopeneA red pigment found in tomatoes and some fruits. It is an antioxidant and may help prevent some types of...
• lymphClear, watery fluid that comes from plasma (the liquid part of the blood) that has leaked through the blood...
• lymph glandA small bean-shaped structure that is part of the body’s immune system. Lymph glands filter substances that...
• lymph nodeA small bean-shaped structure that is part of the body’s immune system. Lymph nodes filter substances that...
• lymph node biopsyA procedure in which all or part of a lymph node is removed and checked under a microscope for signs of...
• lymph node dissectionA surgical procedure in which the lymph nodes are removed and a sample of tissue is checked under a...
• lymph node drainageThe flow of lymph from an area of tissue into a particular lymph node.
• lymph node mappingThe use of dyes and radioactive substances to identify lymph nodes that may contain tumor cells. Also called...
• lymph systemThe tissues and organs that help the body fight infection and disease. The lymph system includes the lymph...
• lymph vesselA thin tube that collects lymph (clear watery fluid) from tissues in different parts of the body and returns...
• lymphadenectomyA surgical procedure in which the lymph nodes are removed and a sample of tissue is checked under a...
• lymphadenopathyDisease or swelling of the lymph nodes.
• lymphangiogramAn x-ray or computer image of the lymphatic system. A dye is injected into the body to make the lymphatic...
• lymphangiographyA procedure that uses x-rays or magnetic resonance imaging (MRI) to make pictures of the lymphatic system. A...
• lymphangiosarcomaA type of cancer that begins in the cells that line lymph vessels.
• lymphangitic carcinomatosisA serious condition in which cancer cells spread from the original (primary) tumor to the lymph vessels (the...
• lymphatic basinA group of lymph nodes that receives and filters lymph that flows from a certain area of the body. Special...
• lymphatic fluidClear, watery fluid that comes from plasma (the liquid part of the blood) that has leaked through the blood...
• lymphatic mappingThe use of dyes and radioactive substances to identify lymph nodes that may contain tumor cells. Also called...
• lymphatic systemThe tissues and organs that help the body fight infection and disease. The lymphatic system includes the...
• lymphatic vesselA thin tube that collects lymph (clear watery fluid) from tissues in different parts of the body and returns...
• lymphaticovenous anastomosisSurgery done to help relieve symptoms of lymphedema (swelling caused by a buildup of lymph in the tissues)...
• lymphedemaA condition in which lymph builds up in tissues and causes swelling. Lymphedema usually affects an arm or...
• LymphirA drug used to treat adults with stage I, stage II, or stage III cutaneous T-cell lymphoma that came back or...
• lymphoblastA lymphocyte that has gotten larger after being stimulated by an antigen. Lymphoblast also refers to an...
• lymphoblasticRefers to lymphoblasts (a type of immature white blood cell).
• lymphoblastic lymphomaAn aggressive (fast-growing) type of non-Hodgkin lymphoma in which too many lymphoblasts (immature white...
• lymphocyteA type of immune cell that is made in the bone marrow and is found in the blood and in lymph tissue. The two...
• lymphocyte-predominant Hodgkin lymphomaA rare type of Hodgkin lymphoma (a cancer of the immune system). It is marked by the presence of...
• lymphocyticRefers to lymphocytes (a type of white blood cell).
• lymphocytic leukemiaA type of cancer in which the bone marrow makes too many lymphocytes (white blood cells).
• lymphocytic leukopeniaA condition in which there is a lower-than-normal number of lymphocytes (a type of white blood cell) in the...
• lymphocytopeniaA condition in which there is a lower-than-normal number of lymphocytes (a type of white blood cell) in the...
• lymphodepleted autologous CD4-directed CAR T cellsA preparation of autologous peripheral blood T lymphocytes (PBTLs) that have been genetically modified to...
• lymphoepitheliomaA type of cancer that begins in the tissues covering the nasopharynx (the upper part of the throat behind the...
• lymphographyA procedure that uses x-rays or magnetic resonance imaging (MRI) to make pictures of the lymphatic system. A...
• lymphoidReferring to lymphocytes, a type of white blood cell. Also refers to tissue in which lymphocytes develop.
• lymphoid progenitor cellA hematopoietic stem cell that is committed to differentiate into T cells, B cells, and natural killer (NK)...
• lymphokine-activated killer cellA white blood cell that is stimulated in a laboratory to kill tumor cells. Also called LAK cell.
• lymphokine-activated killer cellsKiller cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells...
• lymphomaCancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is...
• lymphomatoid granulomatosisDestructive growth of lymph cells, usually involving the lungs, skin, kidneys, and central nervous system...
• lymphomatous leptomeningitisA serious problem that may occur in lymphoma. In lymphomatous leptomeningitis, cancer cells have spread from...
• lymphomatous meningitisA serious problem that may occur in lymphoma. In lymphomatous meningitis, cancer cells have spread from the...
• lymphopeniaA condition in which there is a lower-than-normal number of lymphocytes (a type of white blood cell) in the...
• lymphoplasmacytic lymphomaAn indolent (slow-growing) type of non-Hodgkin lymphoma marked by abnormal levels of IgM antibodies in the...
• lymphopoietin-1One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body...
• lymphoproliferative disorderA disease in which cells of the lymphatic system grow excessively. Lymphoproliferative disorders are often...
• lymphosarcomaAn obsolete term for a malignant tumor of lymphatic tissue.
• lymphoscintigraphyA method used to check the lymph system for disease. A radioactive substance that flows through the lymph...
• lymphostatic elephantiasisA chronic condition marked by extreme swelling in an arm, leg, or other part of the body caused by a buildup...
• lymphovenous bypassSurgery done to help relieve symptoms of lymphedema (swelling caused by a buildup of lymph in the tissues)...
• lymphovenous transplantSurgery done to help relieve symptoms of lymphedema (swelling caused by a buildup of lymph in the tissues)...
• Lynch syndromeAn inherited disorder that increases the risk of developing colorectal cancer, endometrial cancer, ovarian...
• LynparzaA drug used alone or with other drugs to treat adults with certain types of prostate cancer, pancreatic...
• lyophilized black raspberry lozengeA lozenge containing lyophilized black raspberry with potential antioxidant, pro-apoptotic and...
• lyophilized black raspberry saliva substituteA saliva substitute (or artificial saliva) containing lyophilized black raspberry with potential antioxidant...
• lyophilized human recombinant interferon-beta 1a FP-1201A lyophilized form of recombinant human interferon (IFN) beta-1a (rhIFNb-1a), with potential protective...
• lyophilized inactivated group A Streptococcus TARA-002A lyophilized formulation containing cultures of the low-virulent Su strain of group A Streptococcus...
• LyricaA drug used to treat nerve pain caused by diabetes or herpes zoster infection and certain types of seizures...
• lysine-specific demethylase 1 inhibitor INCB059872An orally available inhibitor of lysine-specific demethylase 1 (LSD1; lysine-specific histone demethylase 1A...
• lysisIn biology, lysis refers to the breakdown of a cell caused by damage to its plasma (outer) membrane. It can...
• lysosomeA sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be...
• lyso-thermosensitive liposomal doxorubicinA temperature-sensitive liposomal formulation of the anthracycline antibiotic doxorubicin with potential...
• LytgobiA drug used to treat adults with intrahepatic cholangiocarcinoma (a type of cancer that forms in the bile...
• lyticHaving to do with lysis. In biology, lysis refers to the disintegration of a cell by disruption of its plasma...
• lytic lesionDestruction of an area of bone due to a disease process, such as cancer.

655 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.