lutetium Lu 177-DOTA-ABM-5G

{
  "id": "MLC-T-ONC-014929",
  "term": "lutetium Lu 177-DOTA-ABM-5G",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of 5G, an agent targeting an as of yet undisclosed target, conjugated, via the bifunctional, macrocyclic chelating agent 1,4,7,10-tetra-azacyclododecane-1,4,7,10-tetra-acetic acid (DOTA) and an albumin binding moiety (ABM), to the radioisotope lutetium Lu 177, with potential antineoplastic activity. Upon administration of lutetium Lu 177-DOTA-ABM-5G, the 5G moiety targets and binds to a specific target on tumor cells. Upon binding, lutetium Lu 177 delivers a cytotoxic dose of beta radiation to the tumor cells.",
  "synonyms": [
    "[177Lu]-DOTA-ABM-5G"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lutetium-lu-177-dota-abm-5g/"
}