Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: D (690)

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• D vitaminA family of lipo-soluble steroids important to the absorption, metabolism, and function of calcium and...
• D1/3-Mage-3-His Fusion ProteinA recombinant, chimeric protein derived from a melanoma antigenic epitope (MAGE-3) and recognized by specific...
• D-1MTA substance being studied in the treatment of melanoma and many other types of cancer. D-1MT blocks the...
• D-20761A synthetic luteinizing hormone-releasing hormone (LH-RH) antagonist that suppresses LH and sex steroid...
• DAB389 epidermal growth factorA recombinant fusion protein composed of the diphtheria toxin with the receptor-binding domain replaced by...
• dabigatranA benzimidazole and direct thrombin inhibitor, with anticoagulant activity. Upon administration, dabigatran...
• dabigatran etexilate mesylateAn orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct...
• dabogratinibAn orally bioavailable, selective inhibitor of human fibroblast growth factor receptor 3 (FGFR3), with...
• dabrafenibAn orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. Dabrafenib...
• dabrafenib mesylateA drug used alone or with trametinib to treat low-grade glioma (a type of brain tumor) in children aged 1...
• Dabska tumorA rare, slow-growing tumor of blood vessels that forms in or under the skin anywhere on the body. Dabska...
• DACAA substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. Also called...
• dacarbazineA drug used to treat Hodgkin lymphoma that did not get better with other anticancer drugs and melanoma that...
• dacetuzumabA humanized monoclonal antibody directed against the CD40 receptor with potential antineoplastic activity...
• DACH polymer platinate AP5346A low molecular weight polymer-conjugated platinum complex with potential antineoplastic activity. This...
• DACH-platin micelle NC-4016Polymeric micellar nanoparticles containing diaminocyclohexane platinum (DACH-platin or DACH-Pt) with...
• daclatasvirAn orally available inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) replication...
• dacliximabA drug used to keep the body from rejecting kidney transplants. It is also being studied in the treatment of...
• daclizumabA drug used to keep the body from rejecting kidney transplants. It is also being studied in the treatment of...
• DacogenA drug used to treat adults with myelodysplastic syndromes, including chronic myelomonocytic leukemia. It is...
• dacomitinibA drug used to treat non-small cell lung cancer that has spread, has not already been treated, and has...
• dactinomycinA drug that comes from the bacterium Streptomyces parvulus and is used alone or with other drugs to treat...
• dactolisibAn orally bioavailable imidazoquinoline targeting the phosphatidylinositol 3 kinase (PI3K) and the mammalian...
• DA-EPOCH-RAn abbreviation for a chemotherapy combination used to treat certain types of non-Hodgkin lymphoma. It...
• DA-EPOCH-R regimenAn abbreviation for a chemotherapy combination used to treat certain types of non-Hodgkin lymphoma. It...
• Daflon 500Daflon 500 is a phlebotonic drug and a vascular protecting agent. It is reported to improve microcirculation...
• da-huangThe root of this plant has been used in some cultures to treat certain medical problems. It may have...
• daidzeinAn isoflavone found in soy products. Soy isoflavones are being studied in the prevention of cancer.
• Dakin's solutionA highly diluted solution of sodium hypochlorite (0.5% w/v) with topical anti-infective activity. Dakin's...
• dalanterceptA soluble fusion protein containing the extracellular domain of activin receptor-like kinase-1 (ALK1) fused...
• dalbavancinA second-generation, semi-synthetic lipoglycopeptide antibiotic, with bactericidal activity against a variety...
• dalnicastobartA humanized, agonistic monoclonal antibody targeting the B-cell surface antigen CD40, with potential...
• dalotuzumabA recombinant monoclonal antibody directed against the insulin-like growth factor 1 receptor (IGF1R) with...
• dalpiciclibA cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Upon administration...
• dalpiciclib isethionateThe isethionate salt form of dalpiciclib, an orally bioavailable cyclin-dependent kinase (CDK) inhibitor...
• dalteparin sodiumA drug used to prevent blood clots from forming or to treat blood clots that have formed in patients with...
• dalutrafusp alfaA bifunctional fusion protein composed of a humanized aglycosylated immunoglobulin G1 kappa (IgG1k) antibody...
• D’Amico criteriaA set of clinical criteria that is used to stratify prostate cancers into three risk categories to estimate...
• danaparoid sodiumThe sodium salt form of danaparoid, a synthetic low molecular weight heparin (LMWH) derived from porcine gut...
• danazolA synthetic hormone that is a type of androgen and is used to treat endometriosis. It is being evaluated in...
• danicopanAn orally bioavailable inhibitor of complement factor D (FD; CFD), a serine protease that cleaves complement...
• daniquidoneA water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits...
• danusertibA small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Dalotuzumab binds to and...
• danvatirsenAn antisense oligonucleotide targeting signal transducer and activator of transcription 3 (STAT3) with...
• DanyelzaA drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF) to treat children aged 1 year and...
• dapagliflozinA selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity...
• dapagliflozin propanediolThe propanediol form of dapagliflozin, a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor...
• dapansutrileAn orally bioavailable inhibitor of the innate immune signaling sensor nucleotide-binding domain and...
• daphnetinAn orally bioavailable coumarin derivative and phytochemical extracted from Daphne species, with potential...
• dapolsertibAn orally available inhibitor of PIM family serine/threonine protein kinases and mutant forms of FMS-related...
• daporinadA small molecule with potential antineoplastic and antiangiogenic activities. Daporinad binds to and inhibits...
• dapsoneA drug used to treat acne. It is also used to treat other types of skin diseases and certain bacterial...
• dapsone gel, 5%A gel containing 5% (w/w) dapsone, a synthetic derivative of diamino-sulfone with anti-infective properties...
• daptomycinA drug used to treat certain bacterial skin and bloodstream infections in adults. Daptomycin is also being...
• DARA log of study drugs kept by an investigator running a clinical trial. It lists many things about each drug...
• daratumumabA drug used alone or with other drugs to treat adults with multiple myeloma. It is used in patients whose...
• daratumumab and hyaluronidaseA combination of two drugs used alone or with other drugs to treat adults with certain types of multiple...
• daratumumab and hyaluronidase-fihjA co-formulation composed of daratumumab, a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed...
• daraxonrasibAn orally bioavailable inhibitor of the active, guanosine triphosphate (GTP)-bound form of both wild type and...
• darbepoetin alfaA drug used to treat anemia caused by chronic kidney disease and some types of chemotherapy. Darbepoetin alfa...
• dargistotugAn immunoglobulin G1 (IgG1) human monoclonal antibody directed against T-cell immunoreceptor with...
• darinaparsinA small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of...
• darizmetinibAn orally bioavailable inhibitor of mitogen-activated protein (MAP) kinase kinase 4 (MKK4; MAP2K4), with...
• dark-field microscopeA microscope (device used to magnify small objects) in which objects are lit at a very low angle from the...
• darlifarnibAn orally bioavailable inhibitor of farnesyl transferase, with potential antineoplastic activity. Upon oral...
• darolutamideA drug used alone or with docetaxel to treat adults with certain types of prostate cancer. Darolutamide is...
• daromunA combination of darleukin (L19-IL2), an immunocytokine consisting of the recombinant form of interleukin-2...
• darovasertibAn orally available protein kinase C (PKC) inhibitor with potential immunosuppressive and antineoplastic...
• darunavir/ritonavirA fixed combination of darunavir, a human immunodeficiency virus type 1 (HIV-1) protease nonpeptidic...
• DarzalexA drug used alone or with other drugs to treat adults with multiple myeloma. It is used in patients whose...
• Darzalex FasproA combination of daratumumab and hyaluronidase used alone or with other drugs to treat adults with certain...
• dasabuvirA non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent...
• dasatinibA drug used alone or with other drugs to treat adults and children aged 1 year and older with certain types...
• dasatinib anhydrousAn orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib...
• Data and Safety Monitoring BoardAn impartial group that oversees a clinical trial and reviews the results to see if they are acceptable. This...
• datopotamab deruxtecanA drug used to treat adults with breast cancer that cannot be removed by surgery or has spread to other parts...
• datopotamab deruxtecan-dlnkAn antibody-drug conjugate (ADC) composed of a humanized monoclonal antibody against tumor-associated antigen...
• DatrowayA drug used to treat adults with breast cancer that cannot be removed by surgery or has spread to other parts...
• daunomycin hydrochlorideA drug that comes from the bacterium Streptomyces coeruleorubidus and is used with other drugs as remission...
• daunorubicinAn anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin...
• daunorubicin hydrochlorideA drug that comes from the bacterium Streptomyces coeruleorubidus and is used with other drugs as remission...
• daunorubicin hydrochloride and cytarabine liposomeA form of the anticancer drugs daunorubicin hydrochloride and cytarabine that is contained inside very tiny...
• DaurismoA drug used with low-dose cytarabine to treat acute myeloid leukemia that is newly diagnosed. It is used in...
• davamotecan pegadexamerA formulation of camptothecin, an alkaloid isolated from the Chinese tree Camptotheca acuminata, conjugated...
• dazostinag disodiumThe disodium salt form of dazostinag, an agonist of the stimulator of interferon genes protein (STING...
• DBAA very rare disorder in which the bone marrow doesn’t make enough red blood cells. It is usually seen in the...
• DBEA procedure used to look at the inside of the small intestine. A special instrument made up of two tubes (one...
• DBVEAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
• DBVE regimenAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
• DBVE-PCAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
• DBVE-PC regimenAn abbreviation for a chemotherapy combination used with radiation therapy to treat childhood Hodgkin...
• D&CA procedure to scrape and remove tissue from the inner lining of the uterus. The cervix is dilated (made...
• DC-cholesterol liposomeA cationic cholesterol derivative mixed with dimethylaminoethane-carbamoyl and sonicated to form small...
• DCEP regimenA regimen consisting of dexamethasone, cyclophosphamide, etoposide, and cisplatin that may be used as a...
• DCFAn abbreviation for a chemotherapy combination used to treat certain types of head and neck cancer and...
• D-chiro-inositol and alpha-lactalbumin supplementA supplement composed of D-chiro-inositol and alpha-lactalbumin that may be used to increase insulin...
• DCISA condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not...
• DC-OVA vaccineAn autologous, multivalent dendritic cell vaccine targeting ovarian cancer with potential immunostimulating...
• DCR ligand-bearing liposome-encapsulated melanoma antigens vaccineA cancer cell-based vaccine containing liposome encapsulated melanoma antigens and an immunomodulatory...
• D-cycloserineA drug used to treat tuberculosis. It is also being studied in the treatment of pain and nerve problems...
• DDB2 geneA gene that makes a protein involved in many cell functions, including the repair of damaged DNA. Mutations...
• DDR1-2/VEGFR2-3/PDGFRalpha-beta inhibitor ICP-033An orally bioavailable inhibitor of multiple receptor tyrosine kinases (RTKs), with potential antineoplastic...
• DDSA rare disorder that causes kidney failure before age 3, abnormal development of the sexual organs, and, in...
• DDX nanoparticles-encapsulated IL-12 and RIG-I activating DNA plasmid EG-70A nanoparticle-based formulation composed of a non-viral plasmid DNA vector encoding the human...
• DDX5 degrader FL118An orally bioavailable small molecule derivative of camptothecin, a component found in the bark and stem of a...
• de Gramont regimenA chemotherapy combination used to treat colorectal cancer. It is also used with radiation therapy to treat...
• de novoIn cancer, the first occurrence of cancer in the body.
• de novo mutationA term used to describe a change in the DNA sequence of a gene that is seen for the first time in a person...
• de novo variantA term used to describe a change in the DNA sequence of a gene that is seen for the first time in a person...
• de qi sensationTingling, numbness, heaviness, and other feelings that occur after an acupuncture needle has been properly...
• death capA type of poisonous mushroom that has harmful effects on the kidneys and liver. It is responsible for most...
• death rattleA gurgling sound that comes from the back of the throat of a dying person. It is caused by the build-up of...
• death receptor 4A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• death receptor 5A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• DEBA rare, inherited disorder in which blisters form on the skin and the moist inner lining of some organs and...
• debulkingSurgical removal of as much of a tumor as possible. Debulking may increase the chance that chemotherapy or...
• deceasedDead.
• decitabineA drug used to treat adults with myelodysplastic syndromes, including chronic myelomonocytic leukemia. It is...
• decitabine and cedazuridineA combination of two drugs used to treat adults with myelodysplastic syndromes, including chronic...
• DeclomycinA substance being studied as a way to detect bone growth in patients receiving bisphosphonates (a type of...
• decorticationRemoval of part or all of the external surface of an organ.
• decubitus ulcerDamage to an area of the skin caused by constant pressure on the area for a long time. This pressure can...
• deductibleThe amount of money that a patient with health insurance pays for health care services before the health...
• deep breathingA relaxation technique in which a person focuses on taking slow, deep breaths. Deep breathing involves...
• deep sedationA level of sedation in which a person is in a deep sleep, loses feeling, and is hard to wake up. Deep...
• deep vein thrombosisThe formation of a blood clot in a deep vein of the leg or lower pelvis. Symptoms may include pain, swelling...
• defactinibAn orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic...
• defactinib hydrochlorideThe hydrochloride salt form of defactinib, an orally bioavailable, small-molecule focal adhesion kinase (FAK)...
• defecationMovement of feces (undigested food, bacteria, mucus, and cells from the lining of the intestines) through the...
• deferasiroxA drug used to treat too much iron in the blood caused by blood transfusions. It is being studied in the...
• deferiproneAn orally bioavailable bidentate ligand with iron chelating activity. Deferiprone binds to iron in a 3:1...
• deferoxamineAn iron-chelating agent that removes iron from tumors by inhibiting DNA synthesis and causing cancer cell...
• deferoxamine mesylateThe mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from...
• deferred therapyClosely watching a patient’s condition but not giving treatment unless symptoms appear or change, or there...
• defibrotide sodiumA drug used to treat hepatic veno-occlusive disease (a condition in which small veins in the liver are...
• deficiencyIn medicine, a shortage of a substance (such as a vitamin or mineral) needed by the body.
• deficient DNA mismatch repairDescribes cells that have mutations (changes) in certain genes that are involved in correcting mistakes made...
• deficient mismatch repairDescribes cells that have mutations (changes) in certain genes that are involved in correcting mistakes made...
• definitive diagnosisA final diagnosis that is made after getting the results of tests, such as blood tests and biopsies, that are...
• definitive treatmentThe treatment plan for a disease or disorder that has been chosen as the best one for a patient after all...
• DefitelioA drug used to treat hepatic veno-occlusive disease (a condition in which small veins in the liver are...
• deflazacortA synthetic glucocorticoid prodrug, with anti-inflammatory and immunomodulating properties. Upon...
• defosbarasertibA small-molecule inhibitor of the serine-threonine kinase Aurora B, with potential antineoplastic activity...
• degarelixA long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties...
• degarelix acetateA drug used to treat advanced prostate cancer. Degarelix acetate binds to gonadotropin-releasing hormone...
• degenerative diseaseA disease in which the function or structure of the affected tissues or organs changes for the worse over...
• deglycosylated ricin A chain-conjugated anti-CD19/anti-CD22 immunotoxinsA combination preparation of 1:1 mixture of the immunotoxins HD37-dgA and RFB4-dgA with potential...
• dehydrated human amnion/chorion membraneTissue derived from portions of the placenta donated by the patient during a C-section, with potential...
• dehydrationA condition that occurs when the body loses too much water and other fluids that it needs to work normally...
• dehydroepiandrosteroneA substance being studied in the prevention of cancer. It is a type of steroid. Also called DHEA.
• delamanidA nitro-dihydro-imidazooxazole derivative, with antimycobacterial activity. Upon oral administration...
• delanzomibAn orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the...
• delayed-type hypersensitivity responseAn inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system...
• deleterious mutationA change in the DNA sequence of a gene that causes a person to have or be at risk of developing a certain...
• deletionA type of genetic change that involves the absence of a segment of DNA. It may be as small as a single base...
• deletion 17pThe loss of all or part of the short arm (also called the p arm) of chromosome 17. The deletion 17p leads to...
• deliriumA mental state in which a person is confused and has reduced awareness of their surroundings. The person may...
• delolimogene mupadenorepvecA double-armed oncolytic adenovirus composed of a recombinant genetically modified E1/E3-deleted, adenoviral...
• delta-8-tetrahydrocannabinolAn analogue of tetrahydrocannabinol (THC), with potential antiemetic, anxiolytic, appetite-stimulating...
• delta9-tetrahydrocannabinol/cannabidiol combination agentA sub-micron spray containing a nanoparticle water soluble equimolar solution composed of...
• delta-tocopherolThe orally bioavailable delta form of the naturally-occurring fat-soluble vitamin E, mostly found in soybean...
• delta-tocotrienolThe delta form of the vitamin E family member tocotrienol, with potential antineoplastic activity. Upon...
• demcizumabA humanized monoclonal antibody directed against the N-terminal epitope of Notch ligand DLL4 (delta-like 4)...
• demeclocycline hydrochlorideA substance being studied as a way to detect bone growth in patients receiving bisphosphonates (a type of...
• dementiaA condition in which a person loses the ability to think, remember, learn, make decisions, and solve...
• DemerolA drug used to treat moderate to severe pain. Demerol works by binding to opioid receptors, such as the mu...
• demineralized bone matrixDemineralized allograft bone with osteoinductive activity. Demineralized bone matrices are prepared by acid...
• dencatistatAn orally bioavailable, small molecule inhibitor of cytidine triphosphate synthase 1 (CTPS1), with potential...
• dendrimer-conjugated Bcl-2/Bcl-XL inhibitor AZD0466A drug-dendrimer conjugate composed of a B-cell lymphoma 2 (Bcl-2)/Bcl-XL inhibitor AZD4320 that is...
• dendritic cellA special type of immune cell that is found in tissues, such as the skin, and boosts immune responses by...
• dendritic cell vaccineA vaccine made of antigens and dendritic antigen-presenting cells (APCs).
• dendritic cell-autologous lung tumor vaccineA cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become...
• dendritic cell-CEA peptide vaccineA cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced...
• dendritic cell-gp100-MART-1 antigen vaccineAn autologous dendritic cell vaccine with antineoplastic property. Dendritic cells harvested from cancer...
• dendritic cell-idiotype-keyhole limpet hemocyanin vaccineA cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's...
• dendritic cell-MART-1 peptide vaccineA cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced...
• dendritic cell-precision multiple antigen T lymphocytesA preparation of dendritic cell-precision multiple antigen T-cells (DC-PMAT) that have been induced to...
• dendritic cell-recombinant prostate-specific membrane antigen vaccineA vaccine comprised of autologous dendritic cells pulsed with a recombinant prostate specific membrane...
• dendritic cell-targeting lentiviral vector ID-LV305An engineered lentiviral vector targeting dendritic cells (DCs) and containing nucleic acids encoding for the...
• Dendrobium huoshanense granulesA granules formulation of the Chinese medicinal herbal plant Dendrobium huoshanense (D. huoshanense), with...
• denenicokinA recombinant peptide similar to or identical to endogenous human cytokine interleukin-21 (IL-21) with...
• denfivontinib hydrochlorideThe hydrochloride salt form of denfivontinib, an orally bioavailable inhibitor of both wild type and mutant...
• dengue virus adjuvant PV-001-DVAn attenuated strain of dengue virus that was originally developed as a potential preventative vaccine for...
• denialIn psychiatry, a state in which a person is unable or unwilling to see the truth or reality about an issue or...
• denibulin hydrochlorideThe hydrochloride salt of denibulin, a small molecular vascular disrupting agent, with potential antimitotic...
• denifanstatAn orally bioavailable fatty acid synthase (FASN) inhibitor, with potential antineoplastic activity. Upon...
• denileukin diftitoxA drug used to treat adults with stage I, stage II, or stage III cutaneous T-cell lymphoma that came back or...
• denileukin diftitox-cxdlA cytotoxic recombinant protein consisting of interleukin-2 (IL-2) protein sequences fused to diphtheria...
• denintuzumab mafodotinAn immunoconjugate consisting of an anti-CD19 monoclonal antibody conjugated to the auristatin derivative...
• denominationIn religion, describes a group whose members are organized under a common name and set of rules and have...
• denosumabA drug used to prevent or treat certain bone problems. Denosumab is used under the brand name Xgeva to...
• dense breastA term used to describe breast tissue that has more fibrous and glandular tissue than fatty tissue. Dense...
• dense connective tissueA type of tissue that is mostly made up of tough protein fibers called collagen and cells called fibroblasts...
• dental implantA metal device that is surgically placed in the jawbone. It acts as an anchor for an artificial tooth or...
• dentistA health professional who has special training in caring for the teeth, gums, and other tissues in the mouth.
• Denys-Drash syndromeA rare disorder that causes kidney failure before age 3, abnormal development of the sexual organs, and, in...
• deoxycholic acidA steroidal acid that is a secondary bile acid, with cytolytic activity. Upon subcutaneous administration...
• deoxycytidineA drug that protects healthy tissues from the toxic effects of anticancer drugs.
• deoxycytidine analogue TAS-109An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue...
• deoxycytidine kinase inhibitor TRE-515An orally bioavailable inhibitor of deoxycytidine kinase (dCK), with potential antineoplastic activity. Upon...
• deoxyribonucleic acidThe molecule inside cells that contains the genetic information needed for a person and most other organisms...
• DepakeneA drug used to treat epileptic seizures and bipolar disorder and to prevent migraine headaches. It is also...
• Department of Health and Human ServicesThe U.S. federal government agency responsible for protecting the public’s health and providing important...
• depatuxizumab mafodotinAn antibody-drug conjugate (ADC) consisting of depatuxizumab, a humanized monoclonal antibody directed...
• DEPDC1/MPHOSH1 peptide vaccineA cancer vaccine containing HLA-A*2402-restricted epitopes derived from DEP domain containing 1 (DEPDC1) and...
• depressionA mental condition marked by ongoing feelings of sadness, despair, loss of energy, and difficulty dealing...
• depsipeptideA substance that is made naturally by some bacteria, fungi, and other organisms, and can also be made in the...
• depth of coverageRefers to the number of times a nucleotide is read during sequencing. A greater depth of coverage can...
• derazantinibAn orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential...
• derivativeIn chemistry, a compound produced from or related to another.
• dermabrasionA type of surgery used to make the skin smooth and to improve the way deep scars, pits, and wrinkles look...
• derma-membrane-structure topical creamA topical cream formulation containing physiological lipids with potential anti-xerotic activity...
• dermatitisInflammation of the skin.
• dermatofibrosarcoma protuberansA type of tumor that begins as a hard nodule and grows slowly. These tumors are usually found in the dermis...
• dermatologistA doctor who has special training to diagnose and treat skin problems.
• dermatomyositisA disease that causes inflammation of the skin and muscles. Signs and symptoms include a red or bluish-purple...
• dermatoscopeA small, handheld device used to examine the skin, nails, scalp, and hair. A dermatoscope has a light and a...
• dermisThe inner layer of the two main layers of the skin. The dermis has connective tissue, blood vessels, oil and...
• dermoid cystA type of tumor that contains a cyst filled with tissues that are normally found in the outer layers of the...
• dersimelagonAn orally bioavailable selective, non-peptide melanocortin-1 receptor (MC1R; melanocyte-stimulating hormone...
• DESA synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971...
• DES daughterA female who was exposed before birth to a synthetic form of the hormone estrogen called diethylstilbestrol...
• DES sonA male who was exposed before birth to a synthetic form of the hormone estrogen called diethylstilbestrol...
• desfluraneA fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of...
• desipramine hydrochlorideThe hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA). In the central...
• deslorelinA substance being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or...
• deslorelin acetateA synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential...
• desmoid tumorA rare type of soft tissue tumor that forms in fibrous connective tissue of the body, usually in the abdomen...
• desmoid-type fibromatosisA rare type of soft tissue tumor that forms in fibrous connective tissue of the body, usually in the abdomen...
• desmoplasticCausing or forming adhesions or fibrous connective tissue within a tumor.
• desmoplastic melanomaA rare form of malignant melanoma marked by nonpigmented lesions on sun-exposed areas of the body, most...
• desmoplastic small round cell tumorA rare, aggressive cancer that usually affects young males and usually is located in the abdomen.
• desmopressin acetateAn analogue of the hormone vasopressin with antidiuretic and antihemorrhagic properties. Desmopressin acetate...
• desogestralA synthetic progestogen structurally related to levonorgestrel, with progesterone hormone receptor agonistic...
• desvenlafaxine succinateThe succinate salt form of desvenlafaxine, a synthetic phenethylamine bicyclic derivative with antidepressant...
• detorubicinA semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin...
• Detox-B adjuvantA cancer vaccine adjuvant that consists of an oil droplet emulsion of monophosphoryl lipid A and...
• detoxifyTo make something less poisonous or harmful. It may refer to the process of removing toxins, poisons, or...
• DetoxPCA detoxified, nonspecific immunostimulant consisting of a combination of the active monophosphoryl lipid A...
• deulorlatinibAn orally bioavailable inhibitor of the receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and c-ros...
• deupirfenidoneAn orally bioavailable and deuterated form of the synthetic antifibrotic agent pirfenidone, with potential...
• deuteporfinA photosensitizing agent composed of four sub-porphyrin derivatives, methoxyethy-hydroxyethyl-dipropionic...
• deuterated 3-methylhistidineA derivative of the amino acid histidine labeled with heavy hydrogen (D) used in diagnostic procedures. Upon...
• deuterated enzalutamideA deuterated form of enzalutamide, an orally bioavailable, organic, non-steroidal small molecule targeting...
• deuterated glucoseA deuterium metabolic imaging (DMI) agent composed of glucose labeled with the non-radioactive deuterium (2H...
• deuterated phenanthreneA noncarcinogenic and structural analogue of polycyclic aromatic hydrocarbon (PAH), phenanthrene labeled with...
• deuterium oxideA stable, non-radioactive isotopic form of water, containing 2 atoms of deuterium (D) and one atom of oxygen...
• developmental stageThe physical, mental, and emotional stages a child goes through as he or she grows and matures.
• deviantDifferent from what is normal or standard, especially in terms of behavior.
• deviceAn object that has a specific use. In medicine, wheelchairs, pumps, and artificial limbs are examples of...
• devimistatA racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential...
• DEXA scanA procedure that measures the amount of calcium and other minerals in a bone by passing x-rays with two...
• dexamethasoneA drug used to reduce inflammation and lower the body’s immune response. It is used with other drugs to treat...
• dexamethasone acetate, unspecifiedThe acetate salt form of dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory...
• dexamethasone intravitreal implantAn intravitreal implant containing the corticosteroid dexamethasone embedded in a biodegradable polymer...
• dexamethasone sodium phosphateA sodium phosphate salt form of dexamethasone, a synthetic adrenal corticosteroid with potent...
• dexanabinolA synthetic, terpene-based cannabinoid derivative devoid of cannabinoid receptors 1 and 2 agonist activity...
• dexmedetomidine hydrochlorideThe hydrochloride salt form of dexmedetomidine, an imidazole derivate and active d-isomer of medetomidine...
• dexmethylphenidateA substance being studied in the treatment of fatigue and nervous system side effects caused by chemotherapy...
• dexpanthenol creamAn alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of...
• dexpanthenol mouthwashA mouthwash containing 5% dexpanthenol, the alcoholic analogue of the dextrorotatory isomer of pantothenic...
• dexrazoxaneA bisdioxopiperazine with iron-chelating, chemoprotective, cardioprotective, and antineoplastic activities...
• dexrazoxane hydrochlorideA drug used to treat severe side effects caused by certain types of anticancer drugs. It is used under the...
• dextroamphetamine sulfateThe salt of the dextro-isomer of amphetamine and sympathomimetic amine with CNS stimulating properties...
• dextroamphetamine-amphetamineA combination of drugs used as a treatment for attention deficit hyperactivity disorder (ADHD) and narcolepsy...
• dextromethorphan acetic acidAn anticancer drug that is a type of angiogenesis inhibitor.
• dextromethorphan hydrobromideThe hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol...
• dextromethorphan/bupropion tablet AXS-05A tablet composed of the non-opioid derivative of morphine dextromethorphan (DM) and the aminoketone...
• dextropropoxyphene hydrochlorideThe hydrochloride salt of the d-isomer of the synthetic opiate propoxyphene with weak narcotic analgesic...
• dexverapamilThe R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug...
• dezamizumabA fully humanized monoclonal IgG1 anti-serum amyloid P component (SAP) antibody, with potential anti-amyloid...
• DFMOA substance being studied in the treatment of cancer. Also called difluoromethylornithine.
• DFSIn cancer, the length of time after primary treatment for a cancer ends that the patient survives without any...
• DGK alpha/zeta inhibitor BMS-986408An orally bioavailable inhibitor of both the alpha-isoenzyme of diacylglycerol kinase (DGK-alpha; DGKa) and...
• DGKalpha inhibitor BAY 2862789An orally bioavailable inhibitor of the alpha-isoenzyme of diacylglycerol kinase (DGK alpha; DGKa), with...
• DGK-alpha inhibitor GS-9911An orally bioavailable inhibitor of the alpha-isoenzyme of diacylglycerol kinase (DGK-alpha; DGKa), with...
• DHAP regimenA chemotherapy regimen consisting of dexamethasone, high-dose cytarabine (ARA-C) and cisplatin (Platinol)...
• DHA-paclitaxelA combination of DHA (a natural fatty acid) and paclitaxel (an anticancer drug) being studied in the...
• DHEAA substance being studied in the prevention of cancer. It is a type of steroid. Also called...
• DHEA mustardA steroidal alkylating agent with potential antineoplastic activity. Alkylating agents exert cytotoxic and...
• dHER2+AS15 vaccineA cancer vaccine consisting of a truncated recombinant HER2/neu peptide (dHER2) combined with the...
• DHFR inhibitorA substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that...
• DHHSThe U.S. federal government agency responsible for protecting the public’s health and providing important...
• DHLA rare, aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma caused by changes in the DNA that...
• DHODH inhibitor JBZ-001An orally available inhibitor of dihydroorotate dehydrogenase (DHODH), with potential antineoplastic...
• DHODH inhibitor JNJ-74856665An orally available inhibitor of dihydroorotate dehydrogenase (DHODH), with potential antineoplastic...
• DHODH inhibitor RP7214An orally available inhibitor of dihydroorotate dehydrogenase (DHODH), with potential antineoplastic...
• DHPLNA childhood condition in which abnormal tissue grows on the outer part of one or both kidneys. DHPLN usually...
• DHTA hormone made from testosterone in the prostate, testes, and certain other tissues. It is needed to develop...
• DHX9 inhibitor ATX-559An orally bioavailable inhibitor of the protein RNA helicase A (DHX9; DDX9; RHA), with potential...
• diabetesAny of several diseases in which the kidneys make a large amount of urine. Diabetes usually refers to...
• diabetes insipidusA condition in which a person is very thirsty and makes large amounts of urine. The most common types of...
• diabetes mellitusA disease in which the body does not control the amount of glucose (a type of sugar) in the blood and the...
• diacetylmorphineA highly addictive substance once used to treat severe pain but is now illegal to use or sell in the United...
• diacetylmorphine hydrochlorideThe hydrochloride salt of a diacetyl derivative of the opiate morphine, a naturally occurring alkaloid...
• diacylglycerol kinase zeta inhibitor ASP1570An orally bioavailable inhibitor of diacylglycerol kinase zeta (DGKzeta), with potential antineoplastic...
• diacylglycerol kinase zeta inhibitor BGB-30813An orally bioavailable inhibitor of diacylglycerol kinase zeta (DGKzeta), with potential antineoplastic...
• diagnosisThe process of identifying a disease, condition, or injury from its signs and symptoms. A health history...
• diagnostic mammogramAn x-ray picture of the breast used to check for breast cancer after a lump or other sign or symptom of the...
• diagnostic procedureA test used to help figure out what disease or condition a person has based on their signs and symptoms...
• diagnostic techniqueA type of method or test used to help diagnose a disease or condition. Imaging tests and tests to measure...
• diagnostic testA test used to help figure out what disease or condition a person has based on their signs and symptoms...
• diagnostic trialA research study that evaluates methods of detecting disease.
• dialysisThe process of filtering the blood when the kidneys are not able to cleanse it.
• diameterThe length of a straight line that extends from one edge of a tumor or other object, through its center and...
• diammonium glycyrrhizinateThe diammonium salt of glycyrrhizin and the active constituent in the traditional Chinese medicinal herb...
• Diamond-Blackfan anemiaA very rare disorder in which the bone marrow doesn’t make enough red blood cells. It is usually seen in the...
• diamorphineA highly addictive substance once used to treat severe pain but is now illegal to use or sell in the United...
• dianhydrogalactitolA bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and...
• diaphragmThe thin muscle below the lungs and heart that separates the chest from the abdomen.
• diaphragmatic breathingA relaxation technique in which a person focuses on taking slow, deep breaths. Diaphragmatic breathing...
• diarrheaFrequent or uncontrollable bowel movements that may be soft, loose, or watery. Other symptoms of diarrhea...
• diarylsulfonylurea compound ILX-295501ILX-295501 is a novel sulfonylurea compound that has demonstrated in-vivo antitumor activity against a broad...
• diathermyA procedure in which tissue is heated to destroy abnormal cells. The heat may come from electric currents...
• diazepamA drug used to treat mild to moderate anxiety and tension and to relax muscles. It is a type of...
• diazepinomicinA small-molecule inhibitor of the RAS/RAF/MAPK signaling pathway with potential antineoplastic activity...
• diaziquoneAn anticancer drug that is able to cross the blood-brain barrier and kill cancer cells in the central nervous...
• diazooxonorleucineAn L-glutamine diazo analogue amino acid antibiotic isolated from a species of the bacterial genus...
• diazoxideA benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane...
• dibotermin alfaA recombinant form of human bone morphogenetic protein 2 (rhBMP-2), with potential bone remodeling and...
• DICER1 syndromeA rare, inherited disorder that is caused by a mutation (change) in a gene called DICER1. Having this...
• dichloromethotrexateA chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase...
• diclofenacThe active ingredient in a drug that is used to treat the symptoms of rheumatoid arthritis and is being...
• diclofenac epolamine patchA topical patch containing the epolamine salt form of the nonsteroid anti-inflammatory drug (NSAID)...
• diclofenac sodiumA drug that is used to treat the symptoms of rheumatoid arthritis and is being studied in the prevention and...
• diclofenac sodium gelThe gel form of a drug that is used to treat the symptoms of rheumatoid arthritis and is being studied in the...
• dicumarolA hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K...
• didanosineA drug used in the treatment of infections caused by viruses.
• didemnin BA cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates...
• dideoxyadenosineA synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3' hydroxyl group...
• di-dgA-RFB4An anticancer drug that is a combination of a monoclonal antibody (RFB4) and an immunotoxin (dgA).
• Di-dgA-RFB4 immunotoxinAn immunotoxin of monoclonal antibody (MoAb) RFB4 covalently linked to two deglycosylated ricin toxin A-chain...
• dienogestAn orally-active, semisynthetic, fourth generation, nonethinylated progestogen with potential...
• DIEP flapA type of breast reconstruction in which blood vessels called deep inferior epigastric perforators (DIEP)...
• dietThe things a person eats and drinks.
• dietary counselingA process by which a health professional with special training in nutrition helps people make healthy food...
• dietary protocolA detailed diet plan that states what, how, and when a person will eat and drink. It may be used to test how...
• Dietary Reference IntakesA set of guidelines developed by U.S. and Canadian scientists to give information about the role of nutrients...
• dietary supplementA product that is added to the diet. A dietary supplement is taken by mouth and usually contains one or more...
• diethyldithiocarbamateA sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram...
• diethylstilbestrolA synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971...
• dietitianA health professional who has special training in diet and nutrition. Dietitians offer advice on nutrition...
• differentiated anti-BCMA autologous CAR T cells ARI0002hA preparation of adult human differentiated autologous T lymphocytes that have been ex vivo expanded and...
• differentiated thyroid cancerA type of thyroid cancer in which the cancer cells look similar to normal thyroid cells when viewed under a...
• differentiating agentA substance that causes a cell to change from an immature form to a mature form. In cancer, a differentiating...
• differentiationIn biology, describes the processes by which immature cells become mature cells with specific functions. In...
• differentiation syndromeA serious side effect that may occur in patients with acute promyelocytic leukemia or other types of acute...
• diffuseWidely spread; not localized or confined.
• diffuse hyperplastic perilobar nephroblastomatosisA childhood condition in which abnormal tissue grows on the outer part of one or both kidneys. Diffuse...
• diffuse intrinsic pontine gliomaA rare, fast-growing tumor that forms in cells called glial cells in a part of the brain stem called the...
• diffuse large B-cell lymphomaA term used to describe a group of fast-growing B-cell non-Hodgkin lymphomas (NHL) in which the cancer cells...
• diffuse optical imagingA procedure that uses light waves to create 2-dimensional (2-D) or 3-dimensional (3-D) pictures of tissues...
• diffuse optical tomographyA procedure that uses light waves to create 3-dimensional (3-D) pictures of tissues inside the body. The...
• diflunisalA difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with...
• difluoromethylornithineA substance being studied in the treatment of cancer. Also called DFMO.
• digestible starchA polymeric carbohydrate that is digested by enzymes in the gastrointestinal (GI) tract with dietary...
• digestionThe process of breaking down food into substances the body can use for energy, tissue growth, and repair.
• digestive systemThe organs that take in food and liquids and break them down into substances that the body can use for...
• digestive tractThe organs that food and liquids travel through when they are swallowed, digested, absorbed, and leave the...
• digital breast tomosynthesisA procedure that uses x-rays to take a series of pictures of the inside of the breast from many different...
• digital image analysisA method in which an image or other type of data is changed into a series of dots or numbers so that it can...
• digital mammographyThe use of a computer, rather than x-ray film, to create a picture of the breast.
• digital photographyA type of photography in which images can be viewed on a computer screen.
• digital rectal examinationAn examination in which a doctor inserts a lubricated, gloved finger into the rectum to feel for...
• digitalisA substance used to make drugs that are used to treat several heart conditions, including congestive heart...
• digoxinA drug used to treat irregular heartbeat and some types of heart failure. It is also being studied in the...
• dihematoporphyrin etherUsed in photodynamic therapy, a drug that is absorbed by tumor cells; when exposed to light, it becomes...
• dihydro-5-azacytidineA synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase...
• dihydrofolate reductase inhibitorA substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that...
• dihydrolenperoneA butyrophenone that has been investigated for antineoplastic activity.
• dihydroorotate dehydrogenase inhibitor AG-636An orally available inhibitor of dihydroorotate dehydrogenase (DHODH), with potential antineoplastic...
• dihydroorotate dehydrogenase inhibitor ASLAN003An orally available inhibitor of dihydroorotate dehydrogenase (DHODH), with potential antineoplastic...
• dihydrotestosteroneA hormone made from testosterone in the prostate, testes, and certain other tissues. It is needed to develop...
• diindolylmethaneA substance being studied in the treatment of prostate cancer and in the prevention of cervical cancer...
• DilantinA drug used to treat or prevent seizures or convulsions that may be caused by epilepsy, brain surgery, or...
• dilatation and curettageA procedure to scrape and remove tissue from the inner lining of the uterus. The cervix is dilated (made...
• dilateTo widen or enlarge an opening or hollow structure beyond its usual size, such as the pupil of the eye or a...
• dilation and curettageA procedure to scrape and remove tissue from the inner lining of the uterus. The cervix is dilated (made...
• dilatorA device used to stretch or enlarge an opening.
• DilaudidA drug used to treat moderate to severe pain. It may also be used to treat certain types of cough. Dilaudid...
• DI-Leu16-IL2 immunocytokineA recombinant fusion protein consisting of de-immunized and humanized anti-CD20 monoclonal antibody Leu16...
• dill-based dietary supplementA dietary supplement prepared from Anethum graveolens. Anethum graveolens contains tannins, terpenoids...
• diltiazem hydrochlorideA benzothiazepine calcium channel blocking agent. Diltiazem hydrochloride inhibits the transmembrane influx...
• diluteTo make something thinner, weaker, less concentrated, or less pure by adding something to it.
• DIMA substance being studied in the treatment of prostate cancer and in the prevention of cervical cancer. DIM...
• DimericineA lotion being studied in the treatment of skin cancer and a skin condition called xeroderma pigmentosum. It...
• dimerizing agent-regulated immunoreceptor complex-expressing CD33-specific autologous CAR T cells SC-DARIC33A preparation of equal amounts of autologous CD4-positive and CD8-positive T lymphocytes transduced with a...
• dimesnaA drug that belongs to the family of drugs called chemoprotective agents.
• dimethicone-containing botanicals-based lotionA skin lotion containing various proprietary botanical ingredients and the skin protectant dimethicone, a...
• dimethicone/polymer barrier creamA topical cream containing the silicon-based polymer dimethicone, with potential skin protective activity...
• dimethyl fumarateAn orally bioavailable methyl ester of fumaric acid and activator of nuclear factor erythroid 2...
• dimethyl sulfoxideA colorless liquid that readily dissolves many chemicals and penetrates animal and plant tissues. It is used...
• dimethylbusulfanAn aliphatic analogue of busulfan with potential antineoplastic activity. As an alkylating agent...
• dimethylxanthenone acetic acidAn anticancer drug that is a type of angiogenesis inhibitor.
• DINA condition in which abnormal cells are found in the lining of a breast duct (milk duct). Having DIN may...
• dinaciclibA substance being studied in the treatment of advanced melanoma (a type of skin cancer) and other types of...
• dinitrophenylA small molecule containing 2 phenol rings, characterized as a hapten for use in vaccine preparation...
• dinoprost tromethamineA synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates...
• dinoprostoneA synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been...
• dinutuximabA drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and...
• Dioscorea nipponica Makino extract DNE3An extract of the plant Dioscorea nipponica Makino and inhibitor of both the serine/threonine protein kinase...
• DIPGA rare, fast-growing tumor that forms in cells called glial cells in a part of the brain stem called the...
• diphencyproneA synthetic, potent allergic contact sensitizer with potential immunostimulatory activity. After...
• diphenhydramineA drug used to treat allergies and relieve cough and itching caused by insect bites, sunburn, and poison oak...
• diphenhydramine hydrochlorideThe hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist...
• diphenhydramine hydrochloride/dexamethasone/nystatin magic mouthwashAn oral suspension containing diphenydramine hydrochloride, dexamethasone and nystatin, with anithistaminic...
• diphenoxylate hydrochloride/atropine sulfateA formulation containing the hydrochloride salt form of diphenoxylate, a synthetic opioid of the...
• diphosphonateA drug or substance used to treat hypercalcemia (abnormally high blood calcium) and bone pain caused by some...
• diphtheria toxin fragment-interleukin-2 fusion protein E7777A cytotoxic recombinant fusion protein consisting of the human cytokine interleukin-2 (IL-2) fused to...
• diphtheria toxoid/tetanus toxoid vaccine adsorbedA vaccine containing detoxified tetanus toxoid and detoxified diphtheria toxoid adsorbed on aluminum...
• diphtheria toxoid/tetanus toxoid/acellular pertussis adsorbed, recombinant hepatitis B/inactivated poliovirus vaccine combinedA vaccine consisting of detoxified tetanus toxoid, detoxified diphtheria toxoid, acellular pertussis...
• diphtheria toxoid/tetanus toxoid/acellular pertussis vaccine adsorbedA vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and acellular pertussis...
• diphtheria toxoid/tetanus toxoid/inactivated pertussis vaccineA vaccine containing detoxified tetanus toxoid, detoxified diphtheria toxoid and inactivated pertussis...
• diphtheria-tetanus-acellular pertussis-inactivated poliomyelitis-Haemophilus influenzae type b vaccineA vaccine consisting of detoxified diphtheria toxoid (D), detoxified tetanus toxoid (T), acellular pertussis...
• diploidA term that describes a cell or organism with two complete sets of chromosomes. Most human cells, except for...
• dipyridamoleA drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other...
• direct ophthalmoscopyAn exam of the inside of the back of the eye using an ophthalmoscope (a flashlight-sized instrument with a...
• direct oral anticoagulantAn agent taken orally to prevent blood clot formation by directly inhibiting certain coagulation factors...
• disability insuranceAn insurance plan that pays some of a person’s income when he or she is disabled from an illness or injury...
• disaccharide tripeptide glycerol dipalmitoylA lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity...
• dischargeIn medicine, a fluid that comes out of the body. Discharge can be normal or a sign of disease. Discharge also...
• diseaseAn abnormal condition that affects the structure or function of part or all of the body and is usually...
• disease progressionCancer that continues to grow or spread.
• disease-causing mutationA change in the DNA sequence of a gene that causes a person to have or be at risk of developing a certain...
• disease-free survivalIn cancer, the length of time after primary treatment for a cancer ends that the patient survives without any...
• disease-specific survival rateThe percentage of people in a study or treatment group who have not died from a specific disease in a defined...
• disinfectantAny substance or process that is used primarily on non-living objects to kill germs, such as viruses...
• disitamab vedotinAn antibody-drug conjugate (ADC) composed of trastuzumab, a humanized immunoglobulin G1 (IgG1) monoclonal...
• disorderIn medicine, an abnormal condition that affects the body's function but may or may not have specific signs...
• disorientationA mental state marked by confusion about time, place, or who one is.
• disseminateIn medicine, disseminate means to scatter or spread widely throughout the body’s tissues or organs. For...
• distalIn medicine, refers to a part of the body that is farther away from the center of the body than another part...
• distal bile duct cancerCancer that forms in the area where the ducts from the liver and gallbladder join to form the common bile...
• distal colonThe last part of the colon. The distal colon includes the descending colon (the left side of the colon) and...
• distal pancreatectomySurgery to remove the body and the tail of the pancreas. The spleen may also be removed. A distal...
• distal urethraThe part of the urethra closest to the outside of the body. The urethra is the tube through which urine...
• distal urethral cancerA rare cancer that forms in the part of the urethra that is closest to the outside of the body. The cancer...
• distant cancerRefers to cancer that has spread from the original (primary) tumor to distant organs or distant lymph nodes...
• distant metastasisRefers to cancer that has spread from the original (primary) tumor to distant organs or distant lymph nodes...
• distant recurrenceCancer that has recurred (come back) in another part of the body that is far away from where the original...
• distilled waterAn ultra-pure form of water with potential antineoplastic activity. Derived by boiling impure water and...
• distractionIn medicine, a pain relief method that takes the patient's attention away from the pain.
• distressEmotional, social, spiritual, or physical pain or suffering that may cause a person to feel sad, afraid...
• disufenton sodiumA disulfonyl derivative of phenyl-tert-butyl nitrone (PBN), with potential anti-glioma activity. Although the...
• disulfiramA drug that slows the metabolism of retinoids, allowing them to act over a longer period of time.
• ditiocarb sodiumThe sodium salt form of ditiocarb, an active metabolite of disulfiram, with potential antineoplastic and...
• diuresisAn increase in the amount of urine made by the kidney and passed from the body.
• diureticA type of drug that causes the kidneys to make more urine. Diuretics help the body get rid of extra fluid and...
• divalproex sodiumA stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and...
• divarasibAn orally available inhibitor of the oncogenic KRAS substitution mutation, G12C, with potential...
• diversityHaving people with different physical, social, and personal traits or characteristics in a group or...
• diverticulitisInflammation of one or more pouches or sacs that bulge out from the wall of a hollow organ, such as the...
• diverticulosisA condition marked by small sacs or pouches in the walls of a hollow organ, such as the colon. These sacs can...
• diverticulumA small pouch or sac that bulges out from the wall of a hollow organ, such as the colon.
• DJ-927A substance being studied in the treatment of cancer. It is a type of taxane derivative.
• DKCA rare, inherited disorder that can affect many parts of the body, especially the nails, skin, and mouth. It...
• DKC1 geneA gene that makes a protein involved in protecting and maintaining telomeres (the ends of chromosomes) and in...
• DLK1/ EPHA2/HBB/NRP1/RGS5/TEM1 peptide-pulsed alpha-type-1 polarized dendritic cell vaccineA cell-based cancer vaccine composed of mature polarized dendritic cells (alphaDC1) pulsed with six human...
• DLL3/CD3e tri-specific T-cell activating construct HPN328A recombinant antibody derivative composed of tri-specific T-cell activating construct (TriTAC) containing...
• DM4-conjugated anti-Cripto monoclonal antibody BIIB015A humanized IgG1 monoclonal antibody directed against the cell surface-associated protein Cripto and...
• DM-CHOC-PENA cholesterol carbonate derivative of 4-demethylpenclomedine (DM-PEN) with potential antineoplastic...
• D-methionine formulation MRX-1024A proprietary oral formulation of D-methionine with antioxidant and antimucositis activities. D-methionine...
• dMMRDescribes cells that have mutations (changes) in certain genes that are involved in correcting mistakes made...
• DNAThe molecule inside cells that contains the genetic information needed for a person and most other organisms...
• DNA cross-linking agentA substance that binds DNA nucleotides together and blocks DNA synthesis. In cancer treatment, DNA...
• DNA gene-expression microarrayA process that allows thousands of pieces of DNA that are fixed to a glass slide to be analyzed at one time...
• DNA indexIn medicine, a measure of the amount of DNA or number of chromosomes in cancer cells compared to that in...
• DNA intercalating agentA substance that inserts itself into the DNA structure of a cell and binds to the DNA. This causes DNA...
• DNA interference oligonucleotide PNT2258A liposomal formulation of the 24-mer oligonucleotide PNT100, with potential antineoplastic activity. PNT2258...
• DNA methylaseAn enzyme (a protein that speeds up chemical reactions in the body) that attaches methyl groups to DNA. A...
• DNA methyltransferaseAn enzyme (a protein that speeds up chemical reactions in the body) that attaches methyl groups to DNA. A...
• DNA minor groove binding agent PM060184A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor...
• DNA minor groove binding agent SG2000A sequence-selective pyrrolobenzodiazepine (PBD) dimer with potential antineoplastic activity. Following...
• DNA plasmid encoding human IL-12 phIL12A preparation of non-viral DNA plasmids encoding the human pro-inflammatory cytokine interleukin-12 (IL-12)...
• DNA plasmid encoding interleukin-12 INO-9012A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential...
• DNA plasmid vaccine ITI-1001An off-the-shelf (OTS) plasmid DNA cancer vaccine containing two DNA plasmids, one encoding for the two human...
• DNA plasmid vector pPRA-PSM vaccineA cancer vaccine consisting of a DNA plasmid encoding epitopes of the human preferential antigen of melanoma...
• DNA plasmid-encoding interleukin-12 INO-9012/PSA/PSMA DNA plasmids INO-5150 formulation INO-5151A DNA-based combined formulation composed of INO-5150, DNA plasmids encoding the tumor-associated antigens...
• DNA plasmid-encoding interleukin-12/HPV DNA plasmids therapeutic vaccine MEDI0457A DNA-based combination immunotherapeutic, MEDI0457, composed of VGX-3100, a preparation of DNA plasmids...
• DNA ploidyIn medicine, a measure of the amount of DNA or number of chromosomes in cancer cells compared to that in...
• DNA polymerase theta inhibitor ART6043An orally bioavailable selective and reversible inhibitor of DNA polymerase (pol) theta, with potential...
• DNA polymerase theta inhibitor GSK4524101An orally bioavailable inhibitor of DNA polymerase (pol) theta, with potential chemosensitizing and...
• DNA polymerase theta inhibitor MOMA-313An orally bioavailable inhibitor of DNA polymerase (pol) theta helicase, with potential antineoplastic...
• DNA polymerase theta inhibitor RP-3467An orally bioavailable inhibitor of DNA polymerase (pol) theta, with potential chemosensitizing and...
• DNA repair deficiency syndromeA type of inherited disorder caused by mutations (changes) in certain genes involved in DNA repair. Changes...
• DNA repair disorderA type of inherited disorder caused by mutations (changes) in certain genes involved in DNA repair. Changes...
• DNA repair inhibiting oligonucleotideA preparation of cell-permeant, short double-stranded DNA fragment that mimics double-strand breaks and...
• DNA replicationThe process by which a copy of the DNA in a cell is made before the cell divides.
• DNA sequencingA laboratory process used to learn the exact sequence (order) of the four building blocks, or bases, that...
• DNA-dependent protein kinase inhibitorAny agent that inhibits DNA-dependent protein kinase (DNA-PK).
• DNA-dependent protein kinase inhibitor VX-984An ATP-competitive inhibitor of the catalytic subunit of DNA-dependent protein kinase (DNA-PK), with...
• DNA-dependent protein kinase-targeting siDNA DT01A proprietary preparation of small interfering DNA (siDNA) molecules with potential chemo/radiosensitizing...
• DNAJB1-PRKACA fusion kinase peptide vaccineA cancer peptide vaccine composed of a fusion peptide derived from the fusion protein DnaJ homolog subfamily...
• DNAJB1/PRKACA fusion proteinA fusion protein that is encoded by the DNAJB1/PRKACA fusion gene. This protein contains the N-terminus of...
• DNA-PK inhibitor AZD7648An orally bioavailable ATP-competitive inhibitor of the catalytic subunit of DNA-dependent protein kinase...
• DNA-PK/TOR kinase inhibitor CC-115A dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with...
• DNMT1 inhibitor NTX-301An orally bioavailable inhibitor of human DNA methyltransferase 1 (DNMT1), with potential antineoplastic...
• DNP-modified autologous renal cell carcinoma tumor cell vaccineA cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten...
• DNR orderA legal document in which a person or their proxy (such as a spouse, relative, friend, or lawyer) states that...
• DNR-expressing nasopharyngeal carcinoma-specific cytotoxic T lymphocytesA preparation of autologous, dominant-negative receptor (DNR)-expressing nasopharyngeal carcinoma...

690 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.