MLchartDataset catalogue

DNA minor groove binding agent PM060184

Term · Oncology and biomedicine · MLC-T-ONC-013091

A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.

Table 1. Record
IdentifierMLC-T-ONC-013091
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013091",
  "term": "DNA minor groove binding agent PM060184",
  "field": "Oncology and biomedicine",
  "definition": "A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dna-minor-groove-binding-agent-pm060184/"
}

Record 6,107 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.