DNA minor groove binding agent PM060184
Term · Oncology and biomedicine · MLC-T-ONC-013091
A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.
| Identifier | MLC-T-ONC-013091 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013091",
"term": "DNA minor groove binding agent PM060184",
"field": "Oncology and biomedicine",
"definition": "A marine-derived, synthetically produced compound with potential antineoplastic activity. DNA minor groove-binding agent PM060184 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dna-minor-groove-binding-agent-pm060184/"
}
Record 6,107 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.