carzelesin

{
  "id": "MLC-T-ONC-001479",
  "term": "carzelesin",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An anticancer drug that belongs to the family of drugs called alkylating agents.",
    "A cyclopropylpyrroloindole prodrug analogue and DNA minor groove binding agent, with antineoplastic activity. After hydrolysis, the cyclopropyl group of carzelesin alkylates N3-adenine in a sequence-selective fashion. This results in tumor growth inhibition."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/carzelesin/"
}