Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: C (1,658)

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• C cellA type of cell in the thyroid. C cells make calcitonin, a hormone that helps control the calcium level in the...
• C7R-expressing EBVSTsA preparation of human Epstein-Barr virus (EBV)-specific T lymphocytes (EBVSTs) that have been genetically...
• CA 15-3A protein found on epithelial cells that is part of a larger protein called MUC 1. CA 15-3 may be found in...
• CA 19-9A substance released into the bloodstream by both cancer cells and normal cells. Too much CA 19-9 in the...
• CA 19-9 assayA laboratory test that measures the level of CA 19-9 in the blood. CA 19-9 is a substance released into the...
• CA 27.29A protein found on epithelial cells, which line the inside and outside surfaces of the body. It is part of a...
• CA-125A substance that may be found in high amounts in the blood of patients with certain types of cancer...
• CABIn medicine, a group of non-scientist volunteers that serves as a link between a community and clinical trial...
• CabazitaxelA drug used with prednisone to treat prostate cancer that has spread to other parts of the body and is...
• CabergolineA synthetic ergoline derivative and a long-acting dopamine receptor agonist with high affinity for the...
• CABGSurgery in which a healthy blood vessel taken from another part of the body is used to make a new path for...
• CabiralizumabA humanized monoclonal antibody directed against the tyrosine kinase receptor colony stimulating factor 1...
• c-ABLAn enzyme that is involved in many cell processes, such as cell division. The gene for c-ABL is on chromosome...
• CabliviA drug used with plasma exchange and immunosuppressive therapy to treat acquired thrombotic thrombocytopenic...
• CabometyxA drug that contains the active ingredient cabozantinib-s-malate and is used alone or with other drugs to...
• CabotegravirA human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), that is used for...
• CabozantinibAn orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic...
• Cabozantinib-s-malateA drug used alone or with other drugs under the brand name Cabometyx to treat certain types of differentiated...
• CachexiaA condition marked by a loss of more than 10% of body weight, including loss of muscle mass and fat, in a...
• CADA disease in which there is a narrowing or blockage of the coronary arteries (blood vessels that carry blood...
• CAD systemA computer-based system that uses special software to help look for suspicious areas of tissue on an x-ray...
• CadazolidAn oxazolidinone-type antibiotic, with activity against gram-positive bacteria, including Clostridium...
• CadmiumA metallic element that occurs naturally in tiny amounts in air, water, soil, and food. It is a byproduct of...
• CadonilimabA bispecific antibody directed against the human negative immunoregulatory checkpoint receptors programmed...
• CAFAn abbreviation for a chemotherapy combination used alone or together with other therapies to treat breast...
• CAF regimenAn abbreviation for a chemotherapy combination used alone or together with other therapies to treat breast...
• CafelkibartA monoclonal antibody against C-C-chemokine receptor 8 (CCR8), with potential immunomodulating and...
• Caffeic acidAn orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant...
• CaffeineA substance found in the leaves and beans of the coffee tree, in tea, yerba mate, guarana berries, and in...
• Caffeine-based creamA topical cream containing the alkaloid caffeine in a lipoderm base, with potential anti-inflammatory...
• CAIX inhibitor DTP348An orally bioavailable, nitroimidazole-based sulfamide, carbonic anhydrase IX (CAIX) inhibitor with potential...
• Calaspargase pegolA drug used with other drugs to treat acute lymphoblastic leukemia in children and young adults aged 1 month...
• Calaspargase pegol-mknlAn intravenous formulation containing E.coli-derived L-asparaginase II conjugated with succinimidyl carbonate...
• CalbindinA group of proteins that bind calcium and move it into cells. Calbindins are found in many different tissues...
• CalcificationDeposits of calcium in the tissues. Calcification in the breast can be seen on a mammogram, but cannot be...
• CalcinosisA condition in which abnormal amounts of calcium salts are found in soft tissue, such as muscle.
• CalcipotrieneA synthetic vitamin D derivative usually formulated for topical dermatological use, antipsoriatic...
• CalcitoninA hormone formed by the C cells of the thyroid gland. It helps maintain a healthy level of calcium in the...
• CalcitriolThe active form of vitamin D. Calcitriol is formed in the kidneys or made in the laboratory. It is used as a...
• CalciumA mineral needed for healthy teeth, bones, and other body tissues. It is the most common mineral in the body...
• Calcium aluminosilicate anti-diarrhealA clay compound consisting of aluminosilicate and calcium ions with potential antidiarrheal activity. Calcium...
• Calcium antagonistA type of drug that keeps calcium from entering the muscle cells of the heart and blood vessels. This causes...
• Calcium Ca 41-chloride aqueous solutionA substance used to diagnose and monitor cancer that has spread to the bones. It is also used to study the...
• Calcium Ca 46-chloride aqueous solutionA substance used to study the turnover of bone tissue in certain diseases, such as osteoporosis or cancer...
• Calcium carbonateA form of the mineral calcium that is used to prevent or treat osteoporosis (a decrease in bone mass and...
• Calcium channel blockerA type of drug that keeps calcium from entering the muscle cells of the heart and blood vessels. This causes...
• Calcium chlorideA crystalline, white substance, soluble in water, calcium chloride is the chloride salt of calcium, a...
• Calcium citrateThe citrate salt of calcium. An element necessary for normal nerve, muscle, and cardiac function, calcium as...
• Calcium gluconateThe mineral calcium combined with a form of the sugar glucose. It is used to prevent and treat osteoporosis...
• Calcium infusion testA test used to help diagnose a type of pancreatic islet cell tumor called a gastrinoma. The patient receives...
• Calcium release-activated channel inhibitor CM4620A calcium (Ca2+) release-activated channel (CRAC) inhibitor, with potential anti-inflammatory and protective...
• Calcium release-activated channels inhibitor RP4010A calcium (Ca2+) release-activated channel (CRAC) inhibitor, with potential antineoplastic activity. Upon...
• Calcium saccharateThe calcium salt form of glucaric acid, a natural substance found in many fruits and vegetables, with...
• calcium-41 chloride aqueous solutionAn orally bioavailable aqueous solution containing the chloride salt of the radioisotope calcium-41 (41Ca)...
• calcium-46 chloride aqueous solutionAn orally bioavailable aqueous solution containing the chloride salt of the radioisotope calcium-46 (46Ca)...
• Calculus bovis/Moschus/Olibanum/Myrrha capsuleAn orally available traditional Chinese medicine (TCM)-based capsule formulation containing Calculus bovis...
• CaldonirimabA bispecific antibody directed against the human negative immunoregulatory checkpoint receptors programmed...
• Calendula officinalis/Plantago major/Cochlearia armoracia/ Hamamelis virginiana herbal toothpasteA phytochemical-based toothpaste containing Calendula officinalis, Plantago major, Cochlearia armoracia...
• Calendula ointmentA substance made from the flower of the marigold plant Calendula officinalis. Calendula-based skin products...
• CalfactantA sterile suspension composed of an extract of bovine pulmonary surfactant with surfactant activity...
• Calgranulin AA protein that is made by many different types of cells and is involved in processes that take place both...
• Calgranulin BA protein that is made by many different types of cells and is involved in processes that take place both...
• Caloric intakeRefers to the number of calories (energy content) consumed.
• CalorieA measurement of the energy content of food. The body needs calories as to perform its functions, such as...
• CalquenceA drug used alone to treat adults with chronic lymphocytic leukemia or small lymphocytic lymphoma and adults...
• CALR exon 9 mutant peptide vaccine/Montanide ISA-51A peptide vaccine consisting of a calreticulin (CALR) mutant peptide, CALRLong36, and montanide ISA 51 with...
• CALR geneA gene that makes a protein that is involved in many cell functions. This protein helps control the amount of...
• CalusteroneA 17-alkylated orally active androgenic steroid. Calusterone may alter the metabolism of estradiol and reduce...
• CAMA term used to describe a medical product or practice that is used together with (complementary) or instead...
• CamceviA drug used to treat adults with advanced prostate cancer. Camcevi initially causes the pituitary gland to...
• Camidanlumab tesirineAn immunoconjugate consisting of a human immunoglobulin (Ig) G1 monoclonal antibody directed against the...
• CamizestrantAn orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon...
• CamonsertibAn orally available inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase, with potential...
• CamoteskimabA human immunoglobulin G1 (IgG1) monoclonal antibody against the pro-inflammatory cytokine interleukin-18...
• CampathA drug used to treat B-cell chronic lymphocytic leukemia. It is also being studied in the treatment of other...
• CamphorA substance that comes from the wood and bark of the camphor tree or is made in the laboratory. It has a very...
• Camphor/herbal formulation-based topical plasterA combination topical plaster preparation containing camphor and herbal ingredients including Lamiophlomis...
• CamptosarA drug used alone or with other drugs to treat colorectal cancer that has spread to other parts of the body...
• CamptothecinAn anticancer drug that belongs to the family of drugs called topoisomerase inhibitors.
• Camptothecin analogAn anticancer drug related in structure to camptothecin, a topoisomerase inhibitor. One such drug is...
• Camptothecin analogue TLC388A synthetic analogue of camptothecin with potential antineoplastic and radio-sensitizing activities...
• camptothecin-20(S)-O-propionate hydrateThe hydrated, crystalline propionate ester (attached in position C-20) prodrug of camptothecin, an alkaloid...
• CamrelizumabA monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed...
• CamsirubicinA synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential...
• CanagliflozinA C-glucoside with a thiophene ring that is an orally available inhibitor of sodium-glucose transporter 2...
• CanakinumabA recombinant monoclonal antibody targeting human interleukin-1 beta (IL-1b), with anti-inflammatory and...
• canarypox-hIL-12 melanoma vaccineA vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) that encodes the gene for...
• CancellA liquid mixture that has been promoted as a treatment for cancer and other diseases. None of the ingredients...
• CancerA term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer...
• Cancer antigen 125A substance that may be found in high amounts in the blood of patients with certain types of cancer...
• Cancer cell lineCancer cells that keep dividing and growing over time, under certain conditions in a laboratory. Cancer cell...
• Cancer cell metabolism modulator OMT-111A cancer cell metabolism modulator, with potential antineoplastic activity. Upon administration, OMT-111...
• Cancer clusterThe occurrence of a larger-than-expected number of cases of cancer within a group of people in a geographic...
• Cancer Information ServiceThe National Cancer Institute’s Cancer Information Service (CIS) provides cancer-related information to the...
• Cancer Intervention and Surveillance Modeling NetworkA group of researchers supported by the National Cancer Institute (NCI) who use statistical models to help...
• Cancer of the adrenal cortexA rare cancer that forms in the outer layer of tissue of the adrenal gland (a small organ on top of each...
• Cancer of unknown primary originA case in which cancer cells are found in the body, but the place where the cells first started growing (the...
• Cancer peptide vaccine S-588410A cancer peptide vaccine containing five human leukocyte antigen (HLA)-A*2402-restricted epitope peptides...
• Cancer predisposing gene mutationA term used to describe mutations (changes) in certain genes that may increase a person’s risk of some types...
• Cancer predisposition geneA term used to describe a gene that may increase a person’s risk of developing some types of cancer if it has...
• Cancer prevention vaccineA type of vaccine that helps protect the body against infection with viruses that can cause certain types of...
• Cancer subtypeDescribes the smaller groups that a type of cancer can be divided into, based on certain characteristics of...
• Cancer susceptibility geneA term used to describe a gene that may increase a person’s risk of developing some types of cancer if it has...
• Cancer susceptibility gene mutationA term used to describe mutations (changes) in certain genes that may increase a person’s risk of some types...
• Cancer treatment vaccineA type of treatment that helps the body’s immune system recognize and destroy cancer cells. A cancer...
• Cancer-related post-traumatic stressA condition that develops in some people who are diagnosed with cancer. Symptoms of cancer-related...
• Candesartan cilexetilA synthetic, benzimidazole-derived angiotensin II receptor antagonist prodrug with antihypertensive activity...
• Candida albicans antigen injectionAn injectable formulation composed of antigens derived from the culture filtrate and cells of two different...
• Candida albicans skin test reagentA culture filtrate of cells of Candida albicans propagated in a chemically defined medium and used as a...
• Candida antigen extract patch VDMN-21An dissolvable microarray-based formulation containing an extract of Candida albicans (C. albicans) antigens...
• CandidiasisA condition in which Candida albicans, a type of yeast, grows out of control in moist skin areas of the body...
• CandidosisA condition in which Candida albicans, a type of yeast, grows out of control in moist skin areas of the body...
• CanerpaturevA non-engineered, naturally oncolytic, replication-competent spontaneous herpes simplex virus (HSV) type I...
• Canertinib dihydrochlorideA substance being studied in the treatment of some types of cancer. Canertinib dihydrochloride blocks the...
• Canfosfamide hydrochlorideThe hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity...
• CannabidiolA chemical that comes from the hemp (Cannabis sativa) plant. Cannabidiol contains very low levels of...
• CannabinoidA type of chemical in marijuana that causes drug-like effects all through the body, including the central...
• Cannabinoid-derived inhalation capsule PPP011A capsule-based inhalation formulation containing a blend of synthetic cannabinoids, including cannabidiol...
• CannabinolA cannabinoid isolated from the plant Cannabis that is a metabolite of tetrahydrocannabinol (THC), with...
• CannabisThe dried leaves and flowering tops of the Cannabis sativa or Cannabis indica plant. Cannabis contains active...
• Cannabis extract oil SR capsuleA sustained-release (SR), oil-based oral capsule composed of a cannabis extract, which contains a variety of...
• Cannabis sativa extractAn extract from the flowering top of Cannabis sativa, which contains a variety of cannabinoids such as...
• CantrixilA cyclodextrin-encapsulated, third generation super-benzopyran (SBP) compound with potential antineoplastic...
• CantronA liquid mixture that has been promoted as a treatment for cancer and other diseases. None of the ingredients...
• Cantuzumab ravtansineAn immunotoxin of a humanized monoclonal antibody C242 (MoAb HuC242) conjugated to a derivative of the...
• CAP-1A small piece of a tumor marker called carcinoembryonic antigen (CEA). CEA may be found in the blood of...
• CapecitabineA drug used alone or with other drugs to treat certain types of colorectal cancer, breast cancer, esophageal...
• Capecitabine rapidly disintegrating tabletA rapidly disintegrating film-coated tablet composed of the fluoropyrimidine carbamate antimetabolite...
• Capecitabine/methotrexate/vinorelbine regimenA regimen composed of capecitabine, methotrexate and vinorelbine that can potentially be used in the...
• CapillaryThe smallest type of blood vessel. A capillary connects an arteriole (small artery) to a venule (small vein)...
• Capillary leak syndromeA condition in which fluid and proteins leak out of tiny blood vessels and flow into surrounding tissues...
• Capillary malformationAn overgrowth of capillaries (small blood vessels) near the surface of the skin. Capillary malformations are...
• Capillary malformation-arteriovenous malformation syndromeA rare genetic condition that causes abnormalities of blood vessels, including swelling of the capillaries...
• CAPIRIAn abbreviation for a chemotherapy combination used to treat colorectal cancer that has spread to other parts...
• CAPIRI regimenAn abbreviation for a chemotherapy combination used to treat colorectal cancer that has spread to other parts...
• CapivasertibA drug used with fulvestrant to treat adults with hormone-receptor positive, HER2-negative breast cancer that...
• CaplacizumabA drug used with plasma exchange and immunosuppressive therapy to treat acquired thrombotic thrombocytopenic...
• Caplacizumab-yhdpA humanized, bivalent anti-von Willebrand factor (VWF) nanobody, with potential anti-platelet and...
• CapmatinibAn orally bioavailable inhibitor of the proto-oncogene c-Met (also known as hepatocyte growth factor receptor...
• Capmatinib hydrochlorideA drug used to treat adults with non-small cell lung cancer that has spread and has a certain mutation...
• CAPOXAn abbreviation for a chemotherapy combination used to treat advanced colorectal cancer. It is also being...
• CAPOX regimenAn abbreviation for a chemotherapy combination used to treat advanced colorectal cancer. It is also being...
• CaprelsaA drug used to treat medullary thyroid cancer that is locally advanced and cannot be removed by surgery or...
• Capromab pendetideA substance used to detect prostate cancer. It contains a monoclonal antibody that binds to prostate cells...
• CapsaicinA component of certain plants, including cayenne and red pepper, used topically for peripheral nerve pain. It...
• capsase-9-PP2A interaction inhibitor PEP-010A cell penetrating and interfering peptide composed of a cell-penetrating part that delivers the peptide into...
• CapsuleIn medicine, a sac of tissue and blood vessels that surrounds an organ, joint, or tumor. A capsule is also a...
• Capsule endoscopeA device used to look at the inside of the intestines and other parts of the digestive tract. It is a capsule...
• Capsule endoscopyA procedure used to look at the inside of the intestines and other parts of the digestive tract. The patient...
• CaptoprilA drug used to treat high blood pressure that is also being studied in the prevention of side effects caused...
• CARA special receptor created in the laboratory that is designed to bind to certain proteins on cancer cells...
• CAR NK cells SZ003A preparation of natural killer cells (NKs) expressing a chimeric antigen receptor (CAR) specific for an as...
• CAR T-cell therapyA type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory...
• CaracA drug that contains the active ingredient fluorouracil and is used as a cream to treat actinic keratosis (a...
• CaracemideAn agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits...
• CarbamazepineA tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic...
• CarbamideA substance formed by the breakdown of protein in the liver. The kidneys filter carbamide out of the blood...
• CarbendazimAn anticancer drug that belongs to the family of drugs called antifungal agents.
• CarbenicillinA broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant...
• CarbetimerCarbetimer (carboxyimamidate) is a low molecular weight derivatized copolymer of ethylene and maleic...
• CarbetocinA long-acting synthetic agonist analogue of human oxytocin, with antihemorrhagic and uterotonic activities...
• CarbidopaA hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an...
• Carbidopa/levodopaAn orally available combination of carbidopa, an inhibitor of aromatic amino acid decarboxylation, and...
• CarbogenAn inhaled form of oxygen and carbon dioxide that has more oxygen than air has. It is being studied in the...
• CarbohydrateA sugar molecule. Carbohydrates can be small and simple (for example, glucose) or they can be large and...
• Carbohydrate supplement drinkA nutritional supplement drink containing 12.5% carbohydrates, which may enhance recovery following...
• Carbolic acidA very poisonous chemical substance made from tar and also found in some plants and essential oils (scented...
• Carbomer/polycarbophil-based vaginal gelA carbomer and polycarbophil-based vaginal gel preparation that may be used for vaginal lubrication and for...
• Carbon C 11 alpha-methyltryptophanA radiopharmaceutical containing an analogue of tryptophan, alpha-methyltryptophan (AMT), labeled with carbon...
• Carbon C 11 AZ14193391A radioconjugate composed of AZ14193391, a central nervous system (CNS) penetrant and selective inhibitor of...
• Carbon C 11 erlotinib hydrochlorideThe hydrochloride salt form of the quinazoline derivative erlotinib labeled with the positron-emitting...
• Carbon C 11 glutamineUpon intravenous administration of 11C-glutamine, glutamine is preferentially taken up by cancer cells. Upon...
• Carbon C 11 martinostatA radioconjugate composed of martinostat, a histone deacetylase (HDAC) inhibitor, labeled with the...
• Carbon C 11 metforminA radiopharmaceutical tracer containing the anti-diabetic agent metformin, a biguanide and hydrophilic...
• Carbon C 11 methylaminoisobutyrateA synthetic neutral amino acid analog radiolabeled with carbon C 11 with potential use for metabolic tumor...
• Carbon C 11 N-desmethyl-loperamideA radiopharmaceutical containing N-desmethyl loperamide (dLop) labeled with carbon 11 (11C), used to measure...
• Carbon C 11 PBR-28A radioconjugate composed of a ligand for the 18 kDa translocator protein (TSPO) conjugated to the...
• Carbon C 11 Pittsburgh compound BA radioconjugate composed of the beta-amyloid binding agent Pittsburgh compound B (PiB), a derivative of the...
• Carbon C 11 sarcosineA radiotracer consisting of sarcosine, the N-methyl derivative of the amino acid glycine, labeled with the...
• Carbon C 11 sepantronium bromideA radiotracer composed of the bromide salt form of sepantronium, a small-molecule survivin antagonist and...
• Carbon C 11 YJH08A radioconjugate composed of YJH08, a synthetic glucocorticoid receptor (GR) agonist, labeled with the...
• Carbon C 11-acetateA radioactive substance being studied in positron emission tomography (PET) imaging. Carbon C 11-acetate gets...
• Carbon C 11-cholineA radioactive substance being studied in positron emission tomography (PET) imaging to find certain types of...
• Carbon C 11-choline PET-CT scanA procedure in which a small amount of carbon C 11-choline (a radioactive form of the vitamin choline) is...
• Carbon C 11-JNJ-63779586A radioconjugate composed of JNJ-63779586 labeled with the positron-emitting isotope carbon C 11, with...
• Carbon C 11-osimertinibA radioconjugate composed of osimertinib, a third-generation, orally available, irreversible...
• Carbon C 13 acetateThe non-radioactive, naturally occurring isotope of acetate, carbon C 13 acetate, with potential use for...
• Carbon C 13 dextromethorphanA radioconjugate consisting of dextromethorphan, a synthetic, methylated dextrorotatory analogue of...
• Carbon C 13 hyperpolarized bicarbonateA hyperpolarized (HP) bicarbonate labeled with carbon C 13 (13C), with potential usage in the diagnostic...
• Carbon C 13 idasanutlinA radiopharmaceutical agent composed of an orally available, small-molecule antagonist of MDM2 (mouse double...
• Carbon C 13 lycopeneCarbon C 13 labeled lycopene used as a tracer for carotenoid metabolism studies in vivo. After oral...
• Carbon C 13 phytoeneA 40-carbon hydrocarbon precursor of carotenoids radiolabeled to carbon C 13 and potentially used for tracer...
• Carbon C 13 phytoflueneA 40-carbon hydrocarbon precursor of carotenoids radiolabeled to carbon C 13 and potentially used for tracer...
• Carbon C 13 sodium octanoateThe sodium salt form of the medium-chain fatty acid octanoate, and labeled with the isotope carbon C13, used...
• Carbon C 13/nitrogen N 15-labeled valineA radioconjugate composed of the essential amino acid valine radiolabeled to carbon C 13 and nitrogen N 15...
• Carbon C 14 anlotinib hydrochlorideA radioconjugate composed of the orally bioavailable hydrochloride salt form of anlotinib, a receptor...
• Carbon C 14 dacomitinibA radioconjugate consisting of an orally bioavailable small-molecule inhibitor of the epidermal growth factor...
• Carbon C 14 eribulin acetateA radioconjugate containing the acetate salt of eribulin, labeled with the beta particle-emitting...
• Carbon C 14 fluzoparibAn orally bioavailable radioconjugate composed of fluzoparib, an orally bioavailable inhibitor of poly...
• Carbon C 14 gilteritinibA radioconjugate composed of gilteritinib, an inhibitor of the receptor tyrosine kinases (RTKs) FMS-related...
• Carbon C 14 ibcasertibAn orally bioavailable radioconjugate composed of ibcasertib, an orally bioavailable inhibitor of select...
• Carbon C 14 idasanutlinA radiopharmaceutical agent composed of an orally available, small-molecule antagonist of MDM2 (mouse double...
• Carbon C 14 lenvatinib mesylateA radioconjugate composed of the orally bioavailable mesylate salt form of lenvatinib, a receptor tyrosine...
• Carbon C 14 lerociclibAn orally bioavailable radioconjugate composed of lerociclib, an orally bioavailable inhibitor of...
• Carbon C 14 mivavotinib citrateA radioconjugate composed of the citrate form of mivavotinib, an orally bioavailable selective inhibitor of...
• Carbon C 14 ombrabulinA synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush...
• Carbon C 14 oxaliplatinA radioconjugate composed of the platinum agent oxaliplatin labeled with the isotope carbon C 14, that can be...
• Carbon C 14 pevonedistatAn orally bioavailable radioconjugate composed of pevonedistat, a small molecule inhibitor of...
• Carbon C 14 roniciclibAn orally bioavailable radioconjugate composed of roniciclib, a cyclin dependent kinase (CDK) inhibitor...
• Carbon C 14 selumetinibA radioconjugate containing the orally available selumetinib, an inhibitor of mitogen-activated protein...
• Carbon C 14 telotristat etiprateAn orally bioavailable, tryptophan hydroxylase (TPH) inhibitor prodrug labeled with carbon C 14, which could...
• Carbon C 14 vemurafenibA radioconjugate composed of vemurafenib, an ATP-competitive, small-molecule inhibitor of BRAF(V600E) kinase...
• Carbon C 14-AC0010A radioconjugate composed of AC0010, an orally available, third generation, selective inhibitor of mutant...
• Carbon C 14-labeled ixazomibA radioconjugate comprised of the orally-available, reversible 20S proteasome inhibitor ixazomib and labeled...
• Carbon C 14-pamiparibAn orally bioavailable radioconjugate composed of pamiparib, a nuclear enzyme poly(ADP-ribose) polymerase...
• Carbon C11 nicotineA radiotracer consisting of nicotine radiolabeled with the positron-emitting isotope carbon C11, with...
• Carbon C11 temozolomideA radioconjugate composed of temozolomide, a imidazotetrazine analog of dacarbazine, labeled with the...
• Carbon C14 EGFR inhibitor ASP8273A radioconjugate composed of ASP8273, an orally available, third-generation, mutant-selective, irreversible...
• Carbon C14-labeled carboplatinA radioconjugate composed of the platinum compound carboplatin conjugated to the isotope carbon C 14...
• Carbon dioxideA colorless, odorless gas. It is a waste product made by the body. Carbon dioxide travels in the blood from...
• Carbon monoxideA poisonous gas that has no color or odor. It is given off by burning fuel (as in exhaust from cars or...
• Carbon nanoparticle-based formulationA nanoparticle-based formulation containing carbon, with both a mean size of 150 nm, and potential use as a...
• carbon-11 acetateThe acetate salt of the radioisotope carbon-11. Although the mechanism is unclear, carbon-11 acetate...
• CarboplatinA drug used to treat advanced ovarian cancer that has never been treated or has come back after treatment...
• Carboplatin/etoposide/melphalan regimenA regimen containing carboplatin, etoposide and melphalan used for the treatment of childhood neuroblastoma.
• Carboplatin/paclitaxel regimenA regimen consisting of carboplatin and paclitaxel that may be used for the treatment of breast, kidney...
• Carboplatin-paclitaxel-bevacizumab regimenA chemotherapy combination used to treat advanced, nonsquamous non-small cell lung cancer. It includes the...
• carboplatin-TaxolA chemotherapy combination used to treat endometrial, ovarian, and head and neck cancers, and non-small cell...
• carboplatin-Taxol regimenA chemotherapy combination used to treat endometrial, ovarian, and head and neck cancers, and non-small cell...
• carboplatin-Taxol-bevacizumab regimenA chemotherapy combination used to treat advanced, nonsquamous non-small cell lung cancer. It includes the...
• Carbo-Tax regimenA chemotherapy combination used to treat endometrial, ovarian, and head and neck cancers, and non-small cell...
• CarboxyamidotriazoleAn anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.
• Carboxyamidotriazole orotateThe orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable small molecule with potential...
• Carboxylesterase-expressing allogeneic neural stem cellsA preparation of allogeneic neural stem cells (NSC), derived from a human fetal cell line, that are...
• Carboxymethyl starch topical powderA topical powder formulation composed of an ionic assembly of carboxymethyl starch and calcium, with...
• carboxypeptidase-G2A drug used to treat toxic levels of the anticancer drug methotrexate in the blood of adults and children...
• Carboxyphenyl retinamideA synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and...
• CarbutamideA first-generation sulfonylurea with hypoglycemic activity. Carbutamide was one of the first sulfonylurea...
• Carcinoembryonic antigenA substance that may be found in the blood of people who have colon cancer, other types of cancer or...
• Carcinoembryonic antigen assayA laboratory test that measures the level of carcinoembryonic antigen (CEA) in the blood. An increased amount...
• Carcinoembryonic antigen peptide 1-6DA 9-residue human leukocyte antigen (HLA)-restricted fragment of carcinoembryonic antigen (CEA). Vaccination...
• Carcinoembryonic antigen peptide 1-6D virus-like replicon particles vaccineA cancer vaccine, consisting of alphavirus vector-derived virus-like replicon particles expressing the...
• Carcinoembryonic antigen peptide-1A small piece of a tumor marker called carcinoembryonic antigen (CEA). CEA may be found in the blood of...
• Carcinoembryonic antigen RNA-pulsed DC cancer vaccineA vaccine comprising autologous dendritic cells pulsed with mRNA-encoded Carcinoembryonic Antigen (CEA) that...
• Carcinoembryonic antigen-expressing measles virusAn attenuated oncolytic Edmonston (Ed) strain of measles virus (MV) encoding the soluble extracellular...
• CarcinogenAny substance that causes cancer.
• CarcinogenesisThe process by which normal cells are transformed into cancer cells.
• Carcinoid syndromeA combination of symptoms caused by the release of serotonin and other substances from carcinoid tumors of...
• Carcinoid tumorA slow-growing type of tumor usually found in the gastrointestinal system (most often in the small intestine...
• CarcinomaCancer that begins in the skin or in tissues that line or cover internal organs.
• Carcinoma in situA condition in which abnormal cells that look like cancer cells under a microscope are found only in the...
• Carcinoma of unknown primaryA case in which cancer cells are found in the body, but the place where the cells first started growing (the...
• CarcinomatosisA serious condition in which cancer cells from an original (primary) tumor spread to form many tumors...
• Carcinomatous lymphangitisA serious condition in which cancer cells spread from the original (primary) tumor to the lymph vessels (the...
• Carcinomatous meningitisA serious condition in which cancer cells spread from the original (primary) tumor to the meninges (the thin...
• CarcinosarcomaA malignant tumor that is a mixture of carcinoma (cancer of epithelial tissue, which is skin and tissue that...
• CarcinosisA serious condition in which cancer cells from an original (primary) tumor spread to form many tumors...
• CarcinostaticPertaining to slowing or stopping the growth of cancer.
• CARD11-BCL10-MALT1 complex inhibitor XL114An orally bioavailable inhibitor of the caspase recruitment domain-containing protein 11 (CARD11...
• CardiaThe part of the stomach that is closest to the esophagus. Food and liquids pass through the cardia to enter...
• CardiacHaving to do with the heart.
• Cardiac catheterizationA procedure used to diagnose and treat some heart conditions. During cardiac catheterization, a flexible tube...
• Cardiac pacemakerAn electronic device that is implanted in the body to monitor heart rate and rhythm. It gives the heart...
• Cardiac sarcomaA rare cancer that develops in tissues of the heart. Also called heart cancer.
• Cardiac tamponadeA serious condition that occurs when extra fluid or blood builds up in the space between the heart and the...
• CardinA plant whose leaves, stems, and flowers have been used in some cultures to treat certain medical problems...
• Cardiofaciocutaneous syndromeA rare genetic condition that affects many parts of the body, especially the heart, face, and skin. People...
• CardiologistA doctor who has special training to diagnose and treat diseases of the heart and blood vessels.
• CardiologyA branch of medicine that specializes in diagnosing and treating diseases of the heart, blood vessels, and...
• Cardioprotective agent DH001An orally bioavailable agent, with potential cardiac protective activity. Upon oral administration...
• CardiopulmonaryHaving to do with the heart and lungs.
• Cardiopulmonary resuscitationAn emergency procedure used to restart a person’s heartbeat and breathing after one or both have stopped. It...
• CardiotoxicityToxicity that affects the heart.
• CardiovascularHaving to do with the heart and blood vessels.
• Cardiovascular diseaseA type of disease that affects the heart or blood vessels. The risk of certain cardiovascular diseases may be...
• CarduraA drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes...
• CaregiverA person who gives care to people who need help taking care of themselves. Examples include children, the...
• CarfilzomibA drug used alone or with other drugs to treat adults with multiple myeloma that came back or did not get...
• Caricotamide/tretazicarA combination therapy consisting of the prodrug tretazicar and the enzyme co-substrate caricotamide with...
• Carina of tracheaA ridge at the base of the trachea (windpipe) that separates the openings of the right and left main bronchi...
• CarlumabA human IgG1 kappa monoclonal antibody directed against human CC chemokine ligand 2 (CCL2) with potential...
• CarmustineA drug used alone or with other drugs to treat certain types of brain tumors, Hodgkin lymphoma, and...
• Carmustine implantA drug used with surgery and radiation therapy to treat high-grade glioma that has not already been treated...
• Carmustine in ethanolA formulation containing carmustine dissolved in ethanol for intra-tumoral administration that allows...
• Carmustine sustained-release implant waferA sustained release (SR) implant wafer containing the lipophilic nitrosourea carmustine (BCNU) with...
• Carmustine with propylene glycol formulation VI-0609An injectable ethanol-free formulation containing carmustine with propylene glycol, with antineoplastic...
• Carney complexA rare, inherited disorder marked by dark spots on the skin and tumors in the heart, endocrine glands, skin...
• Carney dyadA rare, inherited disorder marked by tumors of the gastrointestinal tract and tumors that form in embryonic...
• Carney syndromeA rare, inherited disorder marked by dark spots on the skin and tumors in the heart, endocrine glands, skin...
• Carney triadA very rare disorder marked by tumors of the gastrointestinal tract (usually the stomach), tumors that form...
• Carney-Stratakis dyadA rare, inherited disorder marked by tumors of the gastrointestinal tract and tumors that form in embryonic...
• Carney-Stratakis syndromeA rare, inherited disorder marked by tumors of the gastrointestinal tract and tumors that form in embryonic...
• CarnitineA substance made in the muscle and liver tissue and found in certain foods, such as meat, poultry, fish, and...
• CarnitorA form of carnitine, which is a substance made in muscle and liver tissue and found in certain foods, such as...
• CAR-NK cells SZ011A preparation of natural killer cells (NKs) expressing a chimeric antigen receptor (CAR) specific for an as...
• CarnosineA dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with...
• Carnosine/hibiscus-based oral mucoadhesive tabletA plant-based formulation and food supplement composed of carnosine and hibiscus, with potential...
• CarotenoidA yellow, red, or orange substance found mostly in plants, including carrots, sweet potatoes, dark green...
• Carotid arteryA major artery that carries blood from the heart to the head. There is a carotid artery on each side of the...
• CarotuximabA human/murine chimeric monoclonal antibody directed against endoglin (CD105) with potential antiangiogenic...
• Carrageenan-containing gelA water-based, vaginal moisturizing gel containing a mixture of lambda- and kappa- carrageenans, sulfated...
• CarrierIn genetics, a person who has one copy of a mutated (changed) disease-causing gene but has no symptoms or...
• Carrier frequencyThe proportion of individuals in a population who have a single copy of a specific recessive genetic variant...
• Carrier oilAn oil with little or no scent that is used to dilute or “carry” essential oils (scented liquid taken from...
• Carrier rateThe proportion of individuals in a population who have a single copy of a specific recessive genetic variant...
• CarrimycinA 16-membered macrolide antibiotic, with potential antibacterial and immunomodulatory activities. Upon...
• Carrot juiceThe juice from carrots, with potential antioxidant and protective activities. Carrot juice, depending on the...
• carrot/Jilin ginseng/licorice root/tangerine peel/soy beverageA soy-based powdered nutritional supplement drink containing carrot, Jilin ginseng, licorice root and...
• cARTTreatment that uses a combination of three or more drugs to treat HIV infection. cART stops the virus from...
• CAR-T cells AMG 119A preparation of T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR)...
• CartilageA tough, flexible tissue that lines joints and gives structure to the nose, ears, larynx, and other parts of...
• CarubicinAn anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin...
• CarvedilolA synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic...
• Carvedilol phosphateA drug used to treat high blood pressure and certain heart problems. It is also being studied in the...
• Carvedilol phosphate extended-release capsuleAn extended-release capsule formulation containing the phosphate salt of carvedilol, a nonselective...
• CarvyktiA treatment used for adults with multiple myeloma that came back or did not get better after treatment with...
• CarzelesinAn anticancer drug that belongs to the family of drugs called alkylating agents.
• Cascade genetic testingThe process of extending genetic testing to individuals at risk within a family for inheriting a pathogenic...
• Cascade screeningA systematic process for the identification of individuals within a family at risk for a hereditary...
• Cascade testingThe process of extending genetic testing to individuals at risk within a family for inheriting a pathogenic...
• CasdozokitugA human immunoglobulin G1 (IgG1) monoclonal antibody against the p28 subunit of the immunosuppressive...
• Case management nurseA registered nurse who has special training in how to plan, manage, and evaluate all aspects of patient care...
• Case reportA detailed report of the diagnosis, treatment, and follow-up of an individual patient. Case reports also...
• Case seriesA group or series of case reports involving patients who were given similar treatment. Reports of case series...
• Case-control studyA study that compares two groups of people: those with the disease or condition under study (cases) and a...
• Caseinate protein isolateAn isolate comprised of the sodium or calcium salt of the glycoprotein casein, the primary protein found in...
• Casein/whey protein/soy protein/pea protein/fat mix/EPA/DHA-based nutritional supplementA gluten-free, calorie-rich nutritional supplement containing all essential vitamins, minerals, and trace...
• CasirivimabA recombinant, human immunoglobulin G1 (IgG1) kappa monoclonal antibody directed against the spike protein...
• Casirivimab/imdevimabA combination of two monoclonal antibodies, casirivimab and imdevimab, directed against the spike protein...
• CasodexA drug used with another drug to treat prostate cancer that has spread to other parts of the body. It is also...
• Casopitant mesylateThe mesylate salt of a centrally-acting neurokinin 1 (NK1) receptor antagonist with antidepressant and...
• Caspofungin acetateA drug used to prevent or treat infections caused by a fungus (a type of microorganism). It belongs to the...
• Castleman diseaseA rare disorder in which benign (not cancer) growths form in lymph node tissue. There are two main ways that...
• Castrate-resistant prostate cancerProstate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low...
• Castrate-sensitive prostate cancerProstate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are...
• CastrationRemoval or destruction of the testicles or ovaries using radiation, surgery, or drugs. Medical castration...
• CAT scanA procedure that uses a computer linked to an x-ray machine to make a series of detailed pictures of areas...
• CatapresA drug used to treat high blood pressure. It is also being studied in the treatment of certain types of...
• CataractA condition in which the lens of the eye becomes cloudy. Symptoms include blurred, cloudy, or double vision...
• Catch-up vaccinationThe practice of giving a vaccine to people who did not receive it at the recommended age. Catch-up vaccines...
• CatechinA substance found in tea that helps protect cells from damage caused by free radicals. Free radicals are...
• CatecholA chemical originally isolated from a type of mimosa tree. Catechol is used as an astringent, an antiseptic...
• CatecholamineA type of neurohormone (a chemical that is made by nerve cells and used to send signals to other cells)...
• Catequentinib hydrochlorideThe hydrochloride salt form of catequentinib, a receptor tyrosine kinase (RTK) inhibitor with potential...
• Cathepsin-activatable Cy5 fluorescent imaging probe LUM015A cathepsin-activatable fluorescent probe with imaging activity. The cathepsin-activatable fluorescent probe...
• Cathepsin-cleavable NIR substrate probe 6QC-ICGA fluorescently quenched, cysteine cathepsin-cleavable near infrared (NIR) substrate probe containing the dye...
• Cathepsin-cleavable NIR substrate probe 6QC-NIRA cysteine cathepsin-cleavable near infrared (NIR) substrate probe, that may be used for cancer imaging...
• Cathepsin-targeted fluorescent imaging probe VGT-309A fluorescently quenched, cathepsin-activatable, near infrared (NIR) probe containing the dye indocyanine...
• CatheterA flexible tube used to deliver fluids into or withdraw fluids from the body.
• Cationic liposome-encapsulated paclitaxelA cationic liposome preparation of paclitaxel with antineoplastic activity. Paclitaxel, the active ingredient...
• Cationic peptide cream Cypep-1A topical cream containing Cypep-1, a cationic lytic peptide of 27 amino acids, with potential antineoplastic...
• CatumaxomabA trifunctional bispecific monoclonal antibody with potential antineoplastic activity. Catumaxomab has two...
• Cause-specific survivalThe length of time from either the date of diagnosis or the start of treatment for a disease, such as cancer...
• CauterizeTo destroy tissue using a hot or cold instrument, an electrical current, or a chemical that burns or...
• CavityA hollow area or hole. It may describe a body cavity (such as the space within the abdomen) or a hole in a...
• CavrotolimodA spherical nucleic acid (SN)-based agonist of toll-like receptor 9 (TLR9), with potential immunostimulating...
• Caxmotabart entudotinAn antibody-drug conjugate (ADC) composed of trastuzumab, a humanized monoclonal antibody targeting the...
• CB10-277A synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties...
• CBCA measure of the number of red blood cells, white blood cells, and platelets in the blood. The amount of...
• CBC with differentialA measure of the number of red blood cells, white blood cells, and platelets in the blood, including the...
• CBDA chemical that comes from the hemp (Cannabis sativa) plant. CBD contains very low levels of delta-9-THC (the...
• CBEA physical exam of the breast performed by a health care provider to check for lumps or other changes. Also...
• CBL-B inhibitor HST-1011An orally bioavailable, allosteric, small-molecule inhibitor of Casitas B-lineage lymphoma proto-oncogene-b...
• CBL-B inhibitor NX-1607An orally bioavailable, small-molecule inhibitor of Casitas B-lineage lymphoma proto-oncogene-b (CBL-B), with...
• CBL-B inhibitor-treated autologous tumor-infiltrating lymphocytes DeTIL-0255A preparation of autologous tumor-infiltrating lymphocytes (TILs) derived from a patient's tumor that have...
• CBP/beta-catenin modulator E7386An orally bioavailable, specific inhibitor of the canonical Wnt/beta-catenin signaling pathway, with...
• CBP/p300 bromodomain inhibitor AUR-107An orally bioavailable inhibitor of the bromodomain of the histone acetyltransferase (HAT) paralogs, CREB...
• CBP/p300 bromodomain inhibitor FT-7051An orally bioavailable inhibitor of the bromodomain of the histone acetyltransferase (HAT) paralogs, CREB...
• CBP/p300 bromodomain inhibitor OPN-6602An orally bioavailable small molecule inhibitor of the bromodomain of the histone acetyltransferase (HAT)...
• CBP/p300 bromodomain inhibitor TT125-802An orally bioavailable small molecule inhibitor of the bromodomain of the histone acetyltransferase (HAT)...
• CBTA type of psychotherapy that helps patients change their behavior by changing the way they think and feel...
• CBT-1A substance taken from plants that is being studied in the treatment of cancer. It may help drugs kill tumor...
• CcA measure of volume in the metric system. One thousand ccs equal one liter. Also called cubic centimeter...
• CC-1088A drug that is being studied in the treatment of cancer. It is similar but not identical to thalidomide...
• CC-401A second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential...
• CC-4047A drug that is similar to thalidomide and is used alone or with other drugs to treat adults with certain...
• CC-49A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are...
• CC49-streptavidinA substance that is being studied in the treatment of cancer. It is made by combining the monoclonal antibody...
• CC-5013A drug that is similar to thalidomide and is used alone or with other drugs to treat adults with certain...
• CC-8490A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called...
• CCDIA large effort led by the National Cancer Institute to collect, analyze, and share information to address the...
• CCI-779A drug used to treat advanced renal cell carcinoma (a type of kidney cancer). It is also being studied in the...
• CCL21-expressing H1944 cell vaccineA cancer cell vaccine comprised of the allogeneic human lung adenocarcinoma cell line H1944 that has been...
• cCLB8A drug used to treat a rare condition called multicentric Castleman disease in patients who do not have HIV...
• CCNUA drug used to treat brain tumors that have already been treated with surgery or radiation therapy and...
• CCR2 antagonist CCX872-BAn orally available human C-C chemokine receptor type 2 (CCR2) antagonist, with potential immunomodulating...
• CCR2 antagonist PF-04136309An orally available human chemokine receptor 2 (CCR2) antagonist with potential immunomodulating and...
• CCR2/CCR5 antagonist BMS-813160An antagonist of both human C-C chemokine receptor types 2 (CCR2; CD192) and 5 (CCR5; CD195), with potential...
• CCR8 inhibitor IPG7236An orally bioavailable inhibitor of C-C-chemokine receptor 8 (CCR8), with potential immunomodulating and...
• ccRCCA type of kidney cancer in which the cells look clear or very pale when viewed under a microscope. ccRCC...
• CCSGFunds awarded to certain U.S. institutions by the National Cancer Institute (NCI) for them to become cancer...
• CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope plasmid DNA vaccineA plasmid DNA vaccine containing the mammalian expression vector pUMVC3 (pNGVL3) encoding epitopes of CD105...
• CD117A protein found on the surface of many different types of cells. It binds to a substance called stem cell...
• CD11b agonist GB1275An orally bioavailable small molecule agonist of CD11b (integrin alpha-M; ITGAM; integrin alpha M chain)...
• CD122-selective IL-2/Anti-CD25 antibody-like fusion protein ANV419A formulation consisting of lipid nanoparticles (LNPs) encapsulating nucleoside-modified messenger RNA (mRNA)...
• CD123-CD33 compound CAR T cellsA preparation of T lymphocytes transduced with a lentiviral vector expressing a compound chimeric antigen...
• CD123-specific adapter SPRX002A soluble protein antigen-receptor X-linker (sparX) protein containing a CD123 tumor-associated antigen (TAA)...
• CD123-specific targeting module TM123A preparation of soluble adapter molecules consisting of an antigen-binding moiety targeting CD123 linked to...
• CD133 antigen peptide-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with human leukocyte antigen...
• CD134A protein being studied in the treatment of cancer. Substances that attach to CD134 on the surface of T cells...
• CD137 agonistAny agent that targets and activates CD137 (4-1BB; tumor necrosis factor receptor superfamily member 9...
• CD137L/Epstein-Barr virus-targeting autologous dendritic cell vaccineA cell-based cancer vaccine composed of in vitro generated, highly potent, CD137 ligand (CD137L)-dendritic...
• CD137/Nectin-4 bispecific-targeting agent BT748A synthetic tumor targeted immune cell agonist composed of two bicyclic peptides targeting CD137 (4-1BB...
• CD137/PSMA/HSA trispecific-targeting agent CB 307A trispecific T-cell enabler targeting the human tumor-associated antigen (TAA) prostate-specific membrane...
• CD138CAR-CD137/TCRzeta-expressing T lymphocytesT-lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) specific for...
• CD16-based ROR1-targeted NK cell engager PBA-0405An engineered natural killer (NK) cell engager comprised of an anti-receptor tyrosine kinase-like orphan...
• CD16/IL15/CD33 trispecific killer cell engager OXS-3550A trispecific killer engager (TriKE) molecule containing an anti-cluster of differentiation 16 (CD16...
• CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T lymphocytesA preparation of genetically modified central memory (Tcm) enriched T cells transduced with a replication...
• CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T lymphocytesA preparation of genetically modified lymphocytes comprised of CD62L-positive naïve and memory T cells...
• CD19CAR-CD28zeta-4-1BB-expressing allogeneic T lymphocytesAllogeneic T-lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR)...
• CD19CAR-CD3zeta-4-1BB-CD28-expressing autologous T lymphocytesAutologous T-lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR)...
• CD19CAR-CD3zeta-4-1BB-expressing allogeneic T lymphocytesAllogeneic T-lymphocytes transduced with a modified lentiviral vector expressing a chimeric antigen receptor...
• CD19CAR-CD3zeta-expressing autologous T lymphocytesAutologous T lymphocytes transduced with a modified lentiviral vector expressing a chimeric antigen receptor...
• CD19-CD34 tagged metabolically programmed CAR T cellsA preparation of a subset of T lymphocytes, that are metabolically enhanced based on selection and...
• CD19-expressing oncolytic virus CF33A genetically modified oncolytic virus (OV) composed of CF33, a replication competent orthopoxviral chimera...
• CD19R(EQ)-CD28-CD3zeta-EGFRt-expressing T lymphocytesA preparation of genetically modified T cells transduced expressing a chimeric antigen receptor (CAR)...
• CD19-specific adapter molecule SWI019A preparation of adapter molecules consisting of an antibody fragment (Fab) targeting CD19 linked to a 14 aa...
• CD19-targeted 4-1BB ligand RO7227166An immunotherapeutic agent that targets both CD19 and 4-1BB (CDG5:I9necrosis factor receptor superfamily...
• CD19-targeted CAR T cells BZ019A preparation of T lymphocytes that have been genetically modified and transduced with a non-viral vector...
• CD19-targeted CAR T2 cellsA preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor...
• CD19-targeting agentAny agent targeting CD19.
• CD19x22 bicistronic CAR T cellsA preparation of T lymphocytes that have that have been transduced with a bicistronic vector encoding two...
• CD20A protein found on B cells (a type of white blood cell). It may be found in higher than normal amounts in...
• CD20 antigenA protein found on B cells (a type of white blood cell). It may be found in higher than normal amounts in...
• CD200 activation receptor ligand hP1A8A humanized peptide ligand of the CD200 activation receptors (CD200ARs), with potential immunostimulating and...
• CD20-CD19 compound CAR-T cellsA preparation of T lymphocytes transduced with a lentiviral vector expressing a compound chimeric antigen...
• CD20/CD47 bispecific fusion protein CPO107A bispecific fusion protein composed of the anti-CD20 antibody ofatumumab fused to the CD47 binding fragment...
• CD20-targeted Polypeptide TRU-015A proprietary antibody-based single-chain polypeptide with B cell-depleting activity. Significantly smaller...
• CD22 immunotoxinAn immunotoxin composed of an anti-CD22 monoclonal antibody and a toxin moiety, which targets...
• CD22 positiveDescribes cells that have a protein called CD22 on their surface. CD22 is found mostly on B cells (a type of...
• CD24 extracellular domain-IgG1 Fc domain recombinant fusion protein CD24FcA recombinant fusion protein composed of the extracellular domain of the mature human glycoprotein CD24...
• CD28CAR/CD137CAR-expressing T lymphocytesThird generation, chimeric antigen receptor (CAR) cells composed of T-lymphocytes transduced with a...
• CD28/ICOS antagonist ALPN-101An Fc fusion protein comprised of a human inducible T-cell costimulator ligand (ICOSL) variant immunoglobulin...
• CD30 CAR-expressing autologous T lymphocytesA preparation of autologous T lymphocytes that have been genetically modified to express a chimeric antigen...
• CD30 proteinA protein found on some T cells and B cells (two types of white blood cells). It is a receptor for a protein...
• CD33 positiveDescribes cells that have a protein called CD33 on their surface. In normal cells, CD33 is involved in cell...
• CD33CAR-CD3zeta-4-1BB-expressing autologous T-lymphocytesAutologous T-lymphocytes transduced with a retroviral vector expressing a chimeric antigen receptor (CAR)...
• CD33-specific CAR lentiviral vector-transduced allogeneic T lymphocytesA preparation of allogeneic T lymphocytes transduced with a lentiviral vector expressing a chimeric antigen...
• CD33-specific CAR lentiviral vector-transduced autologous T lymphocytesAutologous T lymphocytes transduced with a lentiviral vector expressing a chimeric antigen receptor (CAR)...
• CD34 antigenA protein found on the surface of some bone marrow and blood cells.
• CD34/TK75 retroviral vector-transduced donor lymphocytesA preparation of donor T lymphocytes that are transfected with a retroviral vector encoding a chimeric...
• CD371-specific/YSNVz/IL-18 CAR T cellsA preparation of T lymphocytes engineered to express a chimeric antigen receptor (CAR) specific for the...
• CD38-targeting antibody recruiting molecule KP1237A synthetic, small, bispecific antibody-redirecting/recruiting molecule (ARM) that recognizes the...
• CD3-activating CD19-bi-specific antibody A-319A recombinant T-cell activating bispecific antibody directed against the B-cell-specific membrane protein...
• CD3+/CD19+ cell-depleted autologous hematopoietic stem cellsA preparation of autologous hematopoietic stem cells (HSCs) that have been selectively depleted of...
• CD3+/CD19+ cell-depleted unrelated or partially matched donor-derived allogeneic peripheral blood stem cellsA preparation of allogeneic peripheral blood stem cells (PBSCs) from an unrelated or partially matched...
• CD3/CD28 costimulated autologous T cellsA population of T cells that have been sensitized to vaccine tumor antigen(s) in vivo; collected from the...
• CD4+ CD25+ regulatory T cellsRegulatory T cells that express CD4 and CD25 (interleukin 2 receptor) antigens, with immunomodulating...
• CD40 agonist monoclonal antibody CP-870,893A fully human monoclonal antibody (mAb) agonist of the cell surface receptor CD40 with potential...
• CD40L-augmented autologous tumor infiltrating lymphocytesA preparation of autologous tumor-infiltrating lymphocytes (TILs) derived from a patient's tumor that have...
• CD40L-Fc fusion protein MEDI5083A fusion protein composed of CD40 ligand (CD40L; CD154; TRAP; TNFSF5) fused to a modified immunoglobulin (Ig)...
• CD40-ligandA substance that is being studied in the treatment of cancer. It binds to certain immune cells and may...
• CD44 targeted agent SPL-108A proprietary agent that targets the cancer stem cell (CSC) antigen CD44, with potential antineoplastic...
• CD44v6-specific CAR-T cellsA preparation of genetically modified T lymphocytes transduced with a lentiviral vector encoding a...
• CD45RA-depleted donor T lymphocytesA preparation of donor lymphocytes that have been depleted of CD45RA-positive cells, that can potentially be...
• CD47 antagonist AUR103 calciumThe calcium salt form of AUR103, an orally bioavailable, small molecule antagonist of the human cell surface...
• CD47/SIRPa blocking agent TQB2928An agent blocking the interaction between the leukocyte surface antigen CD47 and the signal regulatory...
• CD4-positive T lymphocyteA type of immune cell that stimulates killer T cells, macrophages, and B cells to make immune responses. A...
• CD4-specific telomerase peptide vaccine UCPVaxA therapeutic peptide vaccine containing the human telomerase reverse transcriptase catalytic subunit...
• CD56-enriched CD3-positive donor lymphocytesA population of CD3-positive lymphocytes expressing the CD56 surface antigen, with potential immunomodulating...
• CD73 inhibitor ATG-037An orally bioavailable inhibitor of the ectoenzyme CD73 (cluster of differentiation 73; 5'-ecto-nucleotidase...
• CD73 inhibitor LY3475070An orally bioavailable inhibitor of the ectoenzyme CD73 (cluster of differentiation 73; 5'-ecto-nucleotidase...
• CD73 inhibitor ORIC-533An orally bioavailable inhibitor of the ectoenzyme CD73 (cluster of differentiation 73; 5'-ecto-nucleotidase...
• CD8+ and CD4+ donor memory T cells-expressing HA1-specific TCRA preparation of CD4+ and CD8+ central memory (CM) T lymphocytes isolated from the peripheral blood of a...
• CD8 enriched young autologous tumor-infiltrating lymphocytesA preparation of autologous young tumor infiltrating lymphocytes (TILs), that are isolated from the patient's...
• CD80A protein found on the surface of some immune system cells, including B cells and monocytes. Cells with CD80...
• CD80 breast cancer vaccineA vaccine comprised of CD80-transfected allogenic breast cancer cells to induce T-cell response.
• CD80-Fc fusion protein ALPN-202A fusion protein composed of the N-terminal Ig variable-like (IgV) domain of CD80 fused to a human...
• CD80-Fc fusion protein FPT155A recombinant fusion protein composed of the extracellular domain (ECD) of human CD80 (B7.1) fused to a human...
• CD80-Fc fusion protein KM602A recombinant fusion protein composed of the extracellular domain (ECD) of human CD80 (B7.1) fused to a human...
• CD8-depleted non-engrafting HLA-mismatched unrelated donor lymphocytesA preparation of allogeneic lymphocytes from an HLA-mismatched donor that have been selectively depleted of...
• CD8+NKG2D+ AKT cellsA preparation of human CD8-positive tumor-specific T lymphocytes engineered to express the natural killer...
• CDAC targeting EGFR mutant BG-60366An orally bioavailable chimeric degradation activation compound (CDAC) targeting mutant epidermal growth...
• CDCA U.S. federal government agency whose mission is to protect public health by preventing and controlling...
• CDC7 inhibitor SGR-2921An orally bioavailable small molecule inhibitor of cell division cycle 7-related protein kinase (CDC7), with...
• CDC7 inhibitor TAK-931An orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase...
• CDC7 inhibitor TQB3824An orally bioavailable inhibitor of cell division cycle 7 (CDC7) kinase, with potential antineoplastic...
• CDC7 kinase inhibitor BMS-863233An orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic...
• CDC7 kinase inhibitor LY3143921 hydrateThe hydrated form of an orally bioavailable inhibitor of cell division cycle 7 (CDC7) kinase, with potential...
• CDC7 kinase inhibitor NMS-1116354An orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic...
• CDDOA substance being studied in the treatment of some types of cancer. CDDO may block enzymes involved in...
• CD-expressing bifidobacterium APS001FA recombinant anaerobic bacterium, Bifidobacterium longum, encoding the cytosine deaminase (CD) gene with...
• CDK inhibitor AT7519An orally bioavailable small molecule with potential antineoplastic activity. AT7519M selectively binds to...
• CDK inhibitor AT7519MA substance being studied in the treatment of some types of cancer. CDK inhibitor AT7519M blocks enzymes...
• CDK inhibitor P276-00A flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. P276-00...
• CDK inhibitor R547An orally bioavailable diaminopyrimidine compound and a cyclin-dependent kinase (CDK) inhibitor with...
• CDK inhibitor SCH 727965A substance being studied in the treatment of advanced melanoma (a type of skin cancer) and other types of...
• CDK inhibitor SNS-032A small aminothiazole molecule and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic...
• CDK1/2/4 inhibitor AG-024322A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits...
• CDK2 degrader NKT3964An orally bioavailable, targeted degrader composed of an E3 ubiquitin ligase-binding moiety that is...
• CDK2 inhibitor ARTS-021An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2 inhibitor BG-68501An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2 inhibitor BLU-222An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2 inhibitor INCB123667An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2 inhibitor INX-315An orally bioavailable small molecule inhibitor of cyclin-dependent kinase 2 (CDK2), with potential...
• CDK2 inhibitor NKT3447An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2 inhibitor PF-07104091An orally bioavailable inhibitor of cyclin-dependent kinase 2 (CDK2), with potential antineoplastic activity...
• CDK2/4/6 inhibitor NUV-422An orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 2 (CDK2), 4 (CDK4) and 6 (CDK6), with...
• CDK2/4/6 inhibitor PF-07224826An orally bioavailable small molecule inhibitor of cyclin-dependent kinase (CDK) types 2 (CDK2), 4 (CDK4) and...
• CDK2/4/6 inhibitor RGT-419BAn orally bioavailable third-generation inhibitor of cyclin-dependent kinase (CDK) types 2 (CDK2), 4 (CDK4)...

1,658 of 17,717 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.