Carbon C 11 sarcosine

{
  "id": "MLC-T-ONC-012256",
  "term": "Carbon C 11 sarcosine",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer consisting of sarcosine, the N-methyl derivative of the amino acid glycine, labeled with the positron-emitting isotope carbon C 11, that can be used for tumor imaging upon positron emission tomography/computed tomography (PET/CT). Upon administration, C-11 sarcosine is taken up by and accumulates in tumor cells, thereby allowing tumor imaging with PET/CT. Sarcosine, a non-proteinogenic amino acid and oncometabolite, is elevated in certain tumor cell types. Its expression seems to correlate with increased tumor invasiveness.",
  "synonyms": [
    "11C-sarcosine",
    "11C-labeled sarcosine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/carbon-c-11-sarcosine/"
}