cationic peptide cream Cypep-1
Term · Oncology and biomedicine · MLC-T-ONC-012338
A topical cream containing Cypep-1, a cationic lytic peptide of 27 amino acids, with potential antineoplastic activity. Upon topical administration, Cypep-1 selectively targets tumor cells with negatively charged cell membranes and ruptures the cell membranes. This leads to tumor cell lysis and the release of neoantigens into the tumor microenvironment (TME) and circulation. This elicits a specific and potent cytotoxic T-lymphocyte (CTL) response against tumor cells expressing these neoantigens. Warts are benign skin tumors caused by human papilloma virus (HPV).
| Identifier | MLC-T-ONC-012338 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012338",
"term": "cationic peptide cream Cypep-1",
"field": "Oncology and biomedicine",
"definition": "A topical cream containing Cypep-1, a cationic lytic peptide of 27 amino acids, with potential antineoplastic activity. Upon topical administration, Cypep-1 selectively targets tumor cells with negatively charged cell membranes and ruptures the cell membranes. This leads to tumor cell lysis and the release of neoantigens into the tumor microenvironment (TME) and circulation. This elicits a specific and potent cytotoxic T-lymphocyte (CTL) response against tumor cells expressing these neoantigens. Warts are benign skin tumors caused by human papilloma virus (HPV).",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/cationic-peptide-cream-cypep-1/"
}
Record 4,329 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.