cancer predisposition gene

{
  "id": "MLC-T-ONC-001369",
  "term": "cancer predisposition gene",
  "field": "Oncology and biomedicine",
  "definition": "A term used to describe a gene that may increase a person’s risk of developing some types of cancer if it has certain mutations (changes). For example, a person who has mutations in the BRCA1 or BRCA2 gene has more risk than normal of developing breast cancer and/or ovarian cancer. Cancer predisposition genes are usually passed from parent to child and may be seen within families. Knowing if a person has a cancer predisposition gene may help prevent, diagnose, and treat cancer. Not all people who have a cancer predisposition gene will develop cancer. Also called cancer susceptibility gene.",
  "synonyms": [
    "cancer susceptibility gene"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/cancer-predisposition-gene/"
}