CDK inhibitor SNS-032

{
  "id": "MLC-T-ONC-012438",
  "term": "CDK inhibitor SNS-032",
  "field": "Oncology and biomedicine",
  "definition": "A small aminothiazole molecule and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. SNS-032 binds to and prevents the phosphorylation of cyclin-dependent kinases, especially CDK2, 7, and 9 that regulate cell cycle progression. Inhibition of CDKs leads to cell cycle arrest and induces apoptosis. As a result, this agent causes cytotoxicity and prevents further tumor cell growth.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cdk-inhibitor-sns-032/"
}