Carmustine with propylene glycol formulation VI-0609
Term · Oncology and biomedicine · MLC-T-ONC-012313
An injectable ethanol-free formulation containing carmustine with propylene glycol, with antineoplastic activity. Upon administration, carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. The ethanol-free formulation of carmustine may lead to fewer toxicities than the ethanol-based formulation.
| Identifier | MLC-T-ONC-012313 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | carmustine ethanol-free formulation VI-0609; carmustine formulation VI-0609 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012313",
"term": "Carmustine with propylene glycol formulation VI-0609",
"field": "Oncology and biomedicine",
"definition": "An injectable ethanol-free formulation containing carmustine with propylene glycol, with antineoplastic activity. Upon administration, carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. The ethanol-free formulation of carmustine may lead to fewer toxicities than the ethanol-based formulation.",
"synonyms": [
"carmustine ethanol-free formulation VI-0609",
"carmustine formulation VI-0609"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/carmustine-with-propylene-glycol-formulation-vi-0609/"
}
Record 4,263 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.