dianhydrogalactitol

{
  "id": "MLC-T-ONC-013034",
  "term": "dianhydrogalactitol",
  "field": "Oncology and biomedicine",
  "definition": "A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest.",
  "abbreviation": "DAG",
  "synonyms": [
    "galactitol",
    "bi-functional alkylating agent VAL-083",
    "diepoxygalactitol",
    "dulcitol diepoxide",
    "diepoxydulcitol",
    "dianhydrodulcitol"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dianhydrogalactitol/"
}