Oncology and biomedicine terminology · MLC-0111
Oncology and biomedicine terms: C (1,658)
- CDK2/4/6 inhibitor SYH2043An orally bioavailable small molecule inhibitor of cyclin-dependent kinase (CDK) types 2 (CDK2), 4 (CDK4) and...
- CDK2/4/6/FLT3 inhibitor FN-1501A small molecule multi-kinase inhibitor of cyclin-dependent kinase (CDK) subtypes 2 (CDK2), 4 (CDK4), and 6...
- CDK4 geneA gene that makes a protein involved in the cell cycle (the process a cell goes through each time it...
- CDK4 inhibitor BGB-43395An orally bioavailable inhibitor of cyclin-dependent kinase 4 (CDK4), with potential antineoplastic activity...
- CDK4 inhibitor P1446A-05A protein kinase inhibitor specific for the cyclin-dependent kinase 4 (CDK4) with potential antineoplastic...
- CDK4 inhibitor PF-07220060An orally bioavailable inhibitor of cyclin-dependent kinase 4 (CDK4), with potential antineoplastic activity...
- CDK4/6 degrader BTX-9341An orally bioavailable bifunctional degrader of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6)...
- CDK4/6 inhibitor BPI-1178An orally bioavailable selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with...
- CDK4/6 inhibitor BPI-16350An orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential...
- CDK4/6 inhibitor CS3002An orally bioavailable selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with...
- CDK4/6 inhibitor FCN-437An orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential...
- CDK4/6 inhibitor GLR2007An orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential...
- CDK4/6 inhibitor HS-10342An orally bioavailable, small molecular, selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4)...
- CDK4/6 inhibitor PRT3645An orally bioavailable, brain-penetrant, selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4)...
- CDK4/6 inhibitor QLS12004An inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential antineoplastic...
- CDK4/6 inhibitor SPH4336An orally bioavailable selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with...
- CDK4/6 inhibitor TQB3303An orally bioavailable selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with...
- CDK4/6 inhibitor TQB3616An orally bioavailable, selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6)...
- CDK4/6 inhibitor UCT-03-008An orally bioavailable inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with potential...
- CDK4/6 inhibitor XZP-3287An orally bioavailable selective inhibitor of cyclin-dependent kinase (CDK) types 4 (CDK4) and 6 (CDK6), with...
- CDK6 geneA gene that makes a protein involved in the cell cycle (the process a cell goes through each time it...
- CDK7 inhibitor LY3405105An orally bioavailable, selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential...
- CDK7 Inhibitor LY3405105 BesylateThe besylate salt form of LY3405105, an orally bioavailable, selective inhibitor of cyclin-dependent kinase 7...
- CDK7 inhibitor Q901A selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential antineoplastic activity. Upon...
- CDK7 inhibitor SY-1365A selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential antineoplastic activity. Upon...
- CDK7 inhibitor SY-5609An orally bioavailable, selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential...
- CDK7 inhibitor TY-2699aAn orally bioavailable inhibitor of cyclin-dependent kinase 7 (CDK7), with potential antineoplastic activity...
- CDK7 inhibitor XL102An orally bioavailable, selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential...
- CDK8/19 inhibitor RVU120An orally bioavailable inhibitor of cyclin-dependent kinases 8 and 19 (CDK8/19), with potential...
- CDK9 inhibitor AZD4573A selective, short-acting inhibitor of the serine/threonine cyclin-dependent kinase 9 (CDK9), the catalytic...
- CDK9 inhibitor GFH009A selective inhibitor of the serine/threonine cyclin-dependent kinase 9 (CDK9), the catalytic subunit of the...
- CDK9 inhibitor KB-0742An orally bioavailable, selective inhibitor of the serine/threonine cyclin-dependent kinase 9 (CDK9), the...
- CDK9 inhibitor PRT2527A selective inhibitor of the serine/threonine cyclin-dependent kinase 9 (CDK9), the catalytic subunit of the...
- CDKN2A geneA gene that makes two major proteins involved in controlling cell growth, cell division, and a type of cell...
- CEAA substance that may be found in the blood of people who have colon cancer, other types of cancer or...
- CEA assayA laboratory test that measures the level of carcinoembryonic antigen (CEA) in the blood. An increased amount...
- CEA peptide-1A small piece of a tumor marker called carcinoembryonic antigen (CEA). CEA may be found in the blood of...
- CEA-MUC-1-TRICOM vaccine CV301A cancer prime/boost vaccine-based immunotherapeutic consisting of a prime, which is comprised of a...
- CEA-targeting agent RG6123An agent targeting the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), with potential...
- CEA/tetanus toxoid T helper epitope fusion protein-expressing DNA plasmid vaccineA plasmid vaccine encoding wild type human carcinoembryonic antigen (CEA) fused to a tetanus toxoid T helper...
- C/EBP beta antagonist ST101A peptide antagonist of the transcription factor CCAAT/enhancer-binding protein beta (C/EBP beta), with...
- CEBPA-targeting saRNA MTL-CEBPA liposomeA lipid-based nanoparticle formulation composed of liposomes encapsulating a small oligonucleotide encoding a...
- cebranopadolAn orally available benzenoid that acts as an opioid peptide receptor agonist for the nociceptin/orphanin FQ...
- cecumA pouch that forms the first part of the large intestine. It connects the small intestine to the colon, which...
- cedarwoodA type of evergreen tree with hard fragrant wood that is a member of the cypress family. The oil from the...
- cedazuridineAn orally available synthetic nucleoside analog derived from tetrahydrouridine (THU) and cytidine deaminase...
- cedazuridine/azacitidine combination agent ASTX030An orally available fixed-dose combination agent containing cedazuridine, a cytidine deaminase (CDA)...
- cediranibAn orally bioavailable indole ether quinazoline derivative and vascular endothelial growth factor receptor...
- cediranib maleateA substance being studied in the treatment of some types of cancer. Cediranib maleate may prevent the growth...
- CefamandoleA second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole is active against...
- cefazolinA beta-lactam antibiotic and first-generation cephalosporin with bactericidal activity. Cefazolin binds to...
- cefazolin sodiumThe sodium salt of cefazolin, a beta-lactam antibiotic and first-generation cephalosporin with bactericidal...
- cefepimeA drug used to treat infection. It belongs to the family of drugs called cephalosporin antibiotics.
- cefepime hydrochlorideThe hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin...
- cefiximeAn antibiotic drug used to treat infection. It belongs to the family of drugs called cephalosporins.
- cefmetazole sodiumThe sodium salt form of cefmetazole, a second-generation, semi-synthetic, beta-lactam cephalosporin...
- cefotaximeA third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits...
- cefoxitin sodiumThe sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with...
- cefpodoxime proxetilA third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity...
- ceftaroline fosamilAn N-phosphono prodrug of the fifth-generation cephalosporin derivative ceftaroline with antibacterial...
- ceftazidime sodiumThe sodium salt of ceftazidime, a third-generation cephalosporin antibiotic with bactericidal activity...
- ceftazidime/avibactam sodiumA combination preparation containing the third-generation cephalosporin ceftazidime and the sodium salt form...
- ceftobiprole medocarilA water-soluble prodrug of ceftobiprole, a pyrrolidinone cephalosporin antibiotic, with bactericidal...
- ceftolozane-tazobactamA combination preparation containing ceftolozane, a semi-synthetic, broad-spectrum, fifth-generation...
- ceftriaxoneA drug used to treat infection. It belongs to the family of drugs called cephalosporin antibiotics.
- ceftriaxone sodiumThe sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with...
- celecoxibA drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory...
- CelexaA drug used to treat depression. It belongs to the families of drugs called antidepressant agents and...
- celiac diseaseA digestive disease that is caused by an immune response to a protein called gluten, which is found in wheat...
- cellIn biology, the smallest unit that can live on its own and that makes up all living organisms and the tissues...
- cell cultureThe growth of microorganisms such as bacteria and yeast, or human, plant, or animal cells in the laboratory...
- cell cycleThe process a cell goes through each time it divides. The cell cycle consists of a series of steps during...
- cell cycle checkpoint/DNA repair antagonist IC83A proprietary agent with potential antineoplastic activity. IC83 appears to target cell cycle checkpoint/DNA...
- cell cycle inhibitorA substance used to block the cell division cycle, which is a series of steps a cell goes through each time...
- cell differentiationThe process during which young, immature (unspecialized) cells take on individual characteristics and reach...
- cell divisionThe process by which a single parent cell splits to form new cells, known as daughter cells. There are two...
- cell membrane-anchored/CSV-targeted IL-12-expressing T lymphocytesA preparation of T lymphocytes engineered to express cell membrane-anchored and cell-surface vimentin...
- cell motilityThe ability of a cell to move.
- cell proliferationAn increase in the number of cells as a result of cell growth and cell division.
- cell respirationA chemical process in which oxygen is used to make energy from carbohydrates (sugars). Also called aerobic...
- cell signalingThe process by which a cell responds to substances outside the cell through signaling molecules found on the...
- cell typeDescribes the kinds of cells found in normal or cancer tissue. The cell type is usually identified by looking...
- cell-cell signalingThe transfer of information from one cell to another. Cells signal each other by direct contact with each...
- CellCeptA drug used to prevent graft-versus-host disease (GVHD) after organ transplants. It is also being studied in...
- cell-cycle regulationAny process that controls the series of events by which a cell goes through the cell cycle. During the cell...
- cell-to-cell signalingThe transfer of information from one cell to another. Cells signal each other by direct contact with each...
- cellular adhesionThe close adherence (bonding) to adjoining cell surfaces.
- cellular adoptive immunotherapyA type of immunotherapy in which T cells (a type of immune cell) are given to a patient to help the body...
- cellular metabolismThe sum of all chemical changes that take place in a cell through which energy and basic components are...
- cellulitisAn acute, spreading infection of the deep tissues of the skin and muscle that causes the skin to become warm...
- celluloseA building block of plant cells and fiber. Cellulose cannot be digested by people, and is used to add bulk to...
- CEMAn abbreviation for a chemotherapy combination used to treat high-risk neuroblastoma. It includes the drugs...
- CEM regimenAn abbreviation for a chemotherapy combination used to treat high-risk neuroblastoma. It includes the drugs...
- cemadotin hydrochlorideThe hydrochloride salt form of cemadotin, a synthetic dolastatin 15 analogue with potential antineoplastic...
- cemdisiranA proprietary formulation composed of small-interfering RNAs (siRNAs) directed against terminal complement...
- cemiplimabA drug that binds to the protein PD-1 to help immune cells kill cancer cells better and is used to treat...
- cemiplimab-rwlcA human monoclonal antibody directed against the negative immunoregulatory human cell surface receptor...
- cemsidomideAn orally bioavailable modulator of the E3 ubiquitin ligase complex containing cereblon (CRL4-CRBN E3...
- cenersenA phosphorothioate oligonucleotide harboring nucleotide sequences complementary to tumor suppressor p53 mRNA...
- cenisertibA water-soluble, synthetic small molecule with potential antineoplastic activity. Cenisertib selectively...
- CENP-E inhibitor GSK-923295AA small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), with potential...
- Centella asiatica/melon extract/vitamins supplementA nutritional supplement composed of Centella asiatica extract, melon extract rich in the antioxidant enzyme...
- Centers for Disease Control and PreventionA U.S. federal government agency whose mission is to protect public health by preventing and controlling...
- centimeterA measure of length in the metric system. There are 100 centimeters in a meter and 2½ centimeters in an inch.
- Centipeda minima decoctionA traditional Chinese medicine (TCM) formulation containing multiple flavones and their glycosides, phenolic...
- central nervous systemThe brain and spinal cord. Also called CNS.
- central nervous system depressantA type of drug that slows down brain activity, which causes the muscles to relax and calms and soothes a...
- central nervous system metastasisCancer that has spread from the original (primary) tumor to the central nervous system (CNS). Also called CNS...
- central nervous system primitive neuroectodermal tumorA type of cancer that arises from a particular type of cell within the brain or spinal cord. Also called CNS...
- central nervous system prophylaxisA type of treatment that uses intrathecal chemotherapy (chemotherapy injected directly into the fluid-filled...
- central nervous system stimulantA type of drug that increases the levels of certain chemicals in the brain and increases alertness...
- central nervous system tumorA tumor of the central nervous system, including brain stem glioma, craniopharyngioma, medulloblastoma, and...
- central venous access catheterA device used to draw blood and give treatments, including intravenous fluids, drugs, or blood transfusions...
- cenvacibartAn immunoglobulin G4 (igG4), human anti-factor XI (FXI) antibody, with potential anti-thrombotic activity...
- cenzestotugAn agonistic recombinant humanized immunoglobulin G1 (IgG1) monoclonal antibody that recognizes the...
- CEP-2563 dihydrochlorideA substance being studied in the treatment of some types of cancer. CEP-2563 dihydrochloride blocks certain...
- CEP-701A drug being studied in the treatment of acute leukemias and some other types of cancer. It binds to a...
- cephalexinAn antibiotic drug that belongs to the family of drugs called cephalosporins.
- cephalosporinA drug used to treat bacterial infections. It belongs to the family of drugs called antibiotics.
- Cephalothin SodiumThe sodium salt form of cephalothin, a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic...
- ceralasertibAn orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR)...
- ceramideA type of lipid (fat) found in the membranes of cells and the covers of nerves. Some ceramides are important...
- ceramide nanoliposomeA lipid-based nanoparticle formulation composed of the apoptosis-inducing sphingolipid ceramide encapsulated...
- ceramide/CLA/cholesterol controlled-release skin barrier emulsionA lipid-rich emulsion containing ceramide, conjugated linoleic acid (CLA) and cholesterol in an emollient...
- c-erbB-2A protein involved in normal cell growth. C-erbB-2 may be made in larger than normal amounts by some types of...
- c-erbB-2 positiveDescribes cells that have a protein called HER2 on their surface. In normal cells, HER2 helps control cell...
- cerclageA procedure in which a special stitch or band is placed around the cervix to help keep it closed during...
- CerdulatinibAn orally bioavailable dual inhibitor of spleen tyrosine kinase (Syk) and Janus-associated kinases (JAK)...
- cerebellar hemangioblastomaA benign, slow-growing tumor in the cerebellum (part of the brain at the back of the head), made up of...
- cerebellar mutism syndromeA condition that may occur in patients who have had surgery to remove a tumor in certain parts of the brain...
- cerebellopontineHaving to do with two structures of the brain, the cerebellum (located at the lower back of the brain) and...
- cerebellumThe portion of the brain in the back of the head between the cerebrum and the brain stem. The cerebellum...
- cereblon modulator BTX-1188An orally bioavailable small molecule modulator of cereblon (CRBN), part of the cullin 4-RING E3 ubiquitin...
- cereblon modulator SP-3164An orally bioavailable avadomide derivative, which contains the stable, active (S)-enantiomer form of...
- cereblon modulator TQB3820An orally bioavailable modulator of cereblon (CRBN), part of the cullin 4-RING E3 ubiquitin ligase complex...
- cerebral edemaA buildup of fluid in the brain that causes swelling and increases pressure inside the skull. This pressure...
- cerebral hemisphereOne half of the cerebrum, the part of the brain that controls muscle functions and also controls speech...
- cerebrospinal fluidThe fluid that flows in and around the hollow spaces of the brain and spinal cord, and between two of the...
- cerebrospinal fluid diversionA process that uses a shunt (a long, thin tube) to drain extra cerebrospinal fluid (CSF) that has built up...
- cerebrospinal fluid shuntA long, thin tube that is placed in a ventricle (fluid-filled space) of the brain to drain extra...
- cerebrovascular accidentIn medicine, a loss of blood flow to part of the brain, which damages brain tissue. Cerebrovascular accidents...
- cerebrumThe largest part of the brain. It is divided into two hemispheres, or halves, called the cerebral...
- ceremonyA series of acts performed for a special occasion or to mark a rite of passage. Ceremonies can be casual or...
- cergutuzumab amunaleukinA recombinant fusion protein comprised of cergutuzumab, a genetically engineered human immunoglobulin G1...
- ceritinibA drug used to treat adults with non-small cell lung cancer that has spread and is ALK positive. It is also...
- certolizumabA Fab fragment of a recombinant, humanized monoclonal antibody directed against the proinflammatory cytokine...
- certolizumab pegolA Fab fragment of a recombinant, humanized monoclonal antibody directed against the proinflammatory cytokine...
- CervarixA vaccine that is no longer available in the United States but is still used in other countries to protect...
- cervicalRelating to the neck, or to the neck of any organ or structure. Cervical lymph nodes are located in the neck...
- cervical adenocarcinomaA type of cervical cancer that begins in the glandular cells of the cervix. These cells make mucus and are...
- cervical cancerCancer that forms in tissues of the cervix (the organ connecting the uterus and vagina). It is usually a...
- cervical dysplasiaA term used to describe the presence of abnormal cells on the surface of the cervix. Cervical dysplasia is...
- cervical intraepithelial neoplasiaA term used to describe abnormal cells that are found on the surface of the cervix when a biopsy is done...
- cervical squamous cell carcinomaA type of cervical cancer that begins in squamous cells of the cervix. Cervical squamous cells are found in...
- cervical squamous intraepithelial neoplasia 1A cervical biopsy finding that means slightly abnormal cells were found on the surface of the cervix...
- cervical squamous intraepithelial neoplasia 2A cervical biopsy finding that means moderately abnormal cells were found on the surface of the cervix...
- cervical squamous intraepithelial neoplasia 2/3A cervical biopsy finding that means a mix of moderately abnormal and severely abnormal cells were found on...
- cervical squamous intraepithelial neoplasia 3A cervical biopsy finding that means severely abnormal cells were found on the surface of the cervix...
- cervicectomySurgery to remove the cervix. There are two types of cervicectomy: simple cervicectomy and radical...
- CerviPrepA device used to deliver drugs directly to the cervix (the lower, narrow end of the uterus that forms a canal...
- cervixThe lower, narrow end of the uterus (womb) that connects the uterus to the vagina (birth canal). The cervix...
- CesametA synthetic pill form of an active chemical in marijuana called delta-9-tetrahydrocannabinol (THC). Cesamet...
- cesarean deliveryThe delivery of a baby through an incision (cut) made in a person’s abdomen and uterus. After the baby is...
- cesarean sectionThe delivery of a baby through an incision (cut) made in a person’s abdomen and uterus. After the baby is...
- cesium Cs 137A radioactive isotope of cesium with an atomic mass of 139 and potential application in radiotherapy. Cesium...
- cesium Cs-131An unstable radioisotope of cesium (Cs) with radiocytotoxic application. Cs-131 is a gamma photon-emitting...
- cEt KRAS antisense oligonucleotide AZD4785A proprietary formulation composed of a high affinity antisense oligonucleotide (ASO) that contains 2'-4'...
- cetrelimabA monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed...
- cetrorelixCetrorelix is a synthetic decapeptide which is structurally related to gonadotrophin-releasing hormone...
- cetuximabA drug used alone or with other drugs to treat certain types of head and neck cancer and colorectal cancer...
- cetuximab sarotalocan sodiumThe sodium salt form of cetuximab sarotalocan, which consists of a chemical conjugate composed of the dye...
- cetuximab-IRDye 800An immunoconjugate comprised of the recombinant chimeric monoclonal antibody cetuximab conjugated to the...
- cetuximab-loaded ethylcellulose polymeric nanoparticles decorated with octreotideA preparation of ethylcellulose polymeric nanoparticles loaded with cetuximab, a recombinant, chimeric...
- CEVAn abbreviation for a chemotherapy combination used to treat retinoblastoma in children. It includes the...
- CEV regimenAn abbreviation for a chemotherapy combination used to treat retinoblastoma in children. It includes the...
- cevidoplenib dimesylateThe dimesylate salt of cevidoplenib, an orally available inhibitor of spleen tyrosine kinase (SYK), with...
- cevimeline hydrochlorideA drug used to treat certain disorders of the salivary gland. It is also being studied as a treatment for dry...
- cevostamabA proprietary recombinant bispecific T-cell engager (BiTE) antibody composed of two single-chain variable...
- CFC syndromeA rare genetic condition that affects many parts of the body, especially the heart, face, and skin. People...
- cFMS tyrosine kinase inhibitor ARRY-382A small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; cFMS) with...
- c-fos antisense oligonucleotideA substance that has been studied in the treatment of cancer and is being studied in the treatment of...
- CFSA condition that lasts for more than 6 months in which a person feels tired most of the time. They may also...
- CgAA protein found inside neuroendocrine cells, which release CgA and certain hormones into the blood. CgA may...
- CGP 48664A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
- CGP-6809A water-soluble nitrosourea that cross-links with DNA, causing inhibition of DNA synthesis.
- Ch14.18A drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and...
- ChAdOx1-PSA/PAP/STEAP1/5T4 prostate cancer vaccine ChAdOx1-PCAQA cancer vaccine consisting of recombinant non-replicating chimpanzee adenovirus Oxford 1 (ChAdOx1) viral...
- Chamberlain procedureA procedure in which a tube is inserted into the chest to view the tissues and organs in the area between the...
- chamomileA family of plants with daisy-like flowers. Two types are German chamomile and Roman or English chamomile...
- ChantixA drug used to help people stop smoking by acting the same way nicotine acts in the brain. It is a type of...
- chaplainA member of the clergy in charge of a chapel or who works with the military or with an institution, such as a...
- charged-particle radiation therapyA type of external radiation therapy that uses a special machine to make invisible, high-energy particles...
- chaste tree berryAn extract made from the fruit of the chaste tree (Vitex agnus-castus) found in parts of Asia and Europe. It...
- checkpoint kinase inhibitor AZD7762A synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity...
- checkpoint kinase inhibitor XL844A synthetic small-molecule inhibitor of checkpoint kinases 1 and 2 (Chk1 and Chk2) with potential...
- cheekboneOne of a pair of bones on each upper side of the face that forms the cheek and part of the eye socket. The...
- chelating agentA chemical compound that binds tightly to metal ions. In medicine, chelating agents are used to remove toxic...
- chemabrasionA procedure used to improve the way certain skin problems look. These problems include acne scars, wrinkles...
- chemexfoliationA procedure used to improve the way certain skin problems look. These problems include acne scars, wrinkles...
- chemicalA substance made up of elements, such as hydrogen or sodium.
- chemical imbalanceToo much or too little of any substance that helps the body work the way it should. A chemical imbalance may...
- chemical peelA procedure used to improve the way certain skin problems look. These problems include acne scars, wrinkles...
- chemo brainA term commonly used to describe thinking and memory problems that a patient with cancer may have before...
- chemoembolizationA procedure in which the blood supply to a tumor is blocked after anticancer drugs are given in blood vessels...
- chemoimmunotherapyChemotherapy combined with immunotherapy. Chemotherapy uses different drugs to kill or slow the growth of...
- chemokineOne of a large group of proteins that is made by certain immune cells and other cells in the body. Chemokines...
- chemokine modulation therapyTherapy used to modulate the activity of chemokine receptors or their ligands, potentially modifying immune...
- chemopreventionThe use of certain drugs or other substances to help lower a person’s risk of developing cancer or keep it...
- chemoprevention studyIn cancer prevention, a clinical trial that studies whether taking certain medicines, vitamins, minerals, or...
- chemoprotective agentA type of drug that helps protect healthy tissue from some of the side effects caused by certain anticancer...
- chemoradiationTreatment that combines chemotherapy with radiation therapy. Also called chemoradiotherapy.
- chemoradiotherapyTreatment that combines chemotherapy with radiation therapy. Also called chemoradiation.
- chemoreductionChemotherapy given to shrink a retinoblastoma tumor before treatment with radiation or surgery. It is a type...
- chemosensitivityThe susceptibility of tumor cells to the cell-killing effects of anticancer drugs.
- chemosensitivity assayA laboratory test that measures the number of tumor cells that are killed by a cancer drug. The test is done...
- chemosensitizerA drug that makes tumor cells more sensitive to the effects of chemotherapy.
- chemotherapeutic agentA drug used to treat cancer.
- chemotherapyTreatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them...
- cherry juiceA juice extracted from bitter and sour cherries.
- chest wallThe skin, fat, muscles, bones, and other tissues that form a protective structure around vital organs in the...
- chest x-rayAn x-ray of the structures and organs inside the chest. An x-ray is a type of high-energy radiation that can...
- chewing gumA semi-solid composed of synthetic, polymerized polysaccharide and flavorings, intended to be chewed to...
- chewing tobaccoA type of smokeless tobacco made from cured tobacco leaves. It may be sweetened and flavored with licorice...
- CHFA condition in which the heart has trouble pumping blood through the body. It may develop over a long period...
- chiasmaAn anatomy term for an X-shaped crossing (for example, of nerves or tendons).
- chickenpoxA highly contagious disease marked by an itchy, blister-like rash caused by the varicella-zoster virus (a...
- childhood acute lymphoblastic leukemia risk group systemA way of grouping patients that is used to plan treatment for children with acute lymphoblastic leukemia. A...
- childhood cancerA term used to describe cancers that occur between birth and 14 years of age. Childhood cancers are very rare...
- Childhood Cancer Data InitiativeA large effort led by the National Cancer Institute to collect, analyze, and share information to address the...
- childhood cancer risk groupA group of children with cancer that has been formed based on certain characteristics of the children and...
- child-life specialistA health care professional who is trained in the emotional and developmental needs of children. A child-life...
- child-life workerA health care professional who is trained in the emotional and developmental needs of children. A child-life...
- Children's Oncology GroupA large group of researchers, hospitals, and cancer centers that get support from the National Cancer...
- chimericHaving parts of different origins. In medicine, refers to a person, organ, or tissue that contains cells with...
- chimeric antigen receptorA special receptor created in the laboratory that is designed to bind to certain proteins on cancer cells...
- chimeric antigen receptor T-cell therapyA type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory...
- chimeric costimulatory converting receptor-modified NK-92 cellsA preparation of genetically-modified natural killer (NK) cells derived from the allogeneic NK-92 cell line...
- chimeric humanized anti-CD47 antibodyA humanized, high-chimeric antibody targeting the human cell surface antigen CD47, with potential...
- chimerismA condition in which some cells or tissues in a person’s body contain at least two different sets of DNA...
- Chinese herbal formulation LC09A traditional Chinese medicine (TCM) decoction containing Herba Epimedii that can be used for...
- Chinese herbal formulation PHY906An oral traditional Chinese herbal formulation in powder form containing a spray-dried preparation of an...
- Chinese herbal medicine YQ1A Chinese herbal medicine, with potential immunostimulating and antineoplastic activities. Although the...
- Chinese herbsHerbs used in Chinese Herbal Therapy for toxicity attenuation. (NCI)
- Chinese meridian theoryIn traditional Chinese medicine, meridians are channels that form a network in the body, through which qi...
- Chinese rhubarbThe root of this plant has been used in some cultures to treat certain medical problems. It may have...
- ChiNing decoctionA decoction of Liang Ge San, a traditional Chinese herbal medicine, with potential anti-inflammatory and...
- CHIPThe presence of somatic mutations in hematopoietic stem cells in an individual without a detectable...
- CHIR-265A substance being studied in the treatment of melanoma. CHIR-265 may block the growth of tumors and the...
- ChiRhoStimA drug used to help diagnose gastrinomas (tumors that cause too much gastric acid to be made) and other...
- chiropractic therapyA type of therapy in which the hands are used to manipulate the spine or other parts of the body. Sometimes...
- chitinA type of polysaccharide (sugar molecule) that is made by some plants and animals. The hard outer shell of...
- chitin oligosaccharides supplement T-ChOSA proprietary, nutritional supplement comprised of chitooligosaccharides extracted from deproteinized and...
- Chk1 inhibitor BBI-355An orally bioavailable small molecule inhibitor of checkpoint kinase 1 (chk1), with potential antineoplastic...
- Chk1 inhibitor GDC-0425An orally bioavailable inhibitor of checkpoint kinase 1 (chk1), with potential antineoplastic and...
- Chk1 inhibitor GDC-0575A small molecule inhibitor of cell cycle checkpoint kinase 1 (Chk1), with potential chemosensitization...
- Chk1 inhibitor LY2880070An orally bioavailable, selective, adenosine triphosphate (ATP)-competitive inhibitor of checkpoint kinase 1...
- CHK1 inhibitor MK-8776An agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and...
- Chk1 inhibitor PEP07An orally bioavailable inhibitor of checkpoint kinase 1 (Chk1), with potential antineoplastic and...
- CHK1 inhibitor PF-477736A proprietary compound targeting cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiation...
- Chk1 inhibitor SRA737An orally bioavailable inhibitor of checkpoint kinase 1 (chk1), with potential antineoplastic and...
- Chlamydophila psittaciA type of bacterium that can infect humans and animals. It spreads to humans from infected birds and can...
- chlorambucilA drug used to treat chronic lymphocytic leukemia, Hodgkin lymphoma, and certain types of non-Hodgkin...
- chlorambucil-prednisoneA chemotherapy combination used to treat chronic lymphocytic leukemia (CLL). It includes the drugs...
- chlorambucil-prednisone regimenA chemotherapy combination used to treat chronic lymphocytic leukemia (CLL). It includes the drugs...
- chlorhexidineA biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is...
- chlorhexidine gluconateThe gluconate salt form of chlorhexidine, a biguanide compound used as an antiseptic agent with topical...
- chlorhexidine gluconate skin cleanserA skin cleanser containing chlorhexidine gluconate. Chlorhexidine gluconate is a biguanide compound used as...
- chlorhexidine/ethyl alcohol mouthwashA mouthwash containing the biguanide chlorhexidine and ethyl alcohol, with topical antibacterial activity...
- chlorineA chemical used in manufacturing, as a bleach, and to kill bacteria and other organisms in water.
- chlorine dioxide sterilizationA sterilization process that uses chlorine dioxide at ambient temperatures to kill microorganisms. This...
- chlorogenic acidA polyphenol and the ester of caffeic acid and quinic acid that is found in coffee and black tea, with...
- chloromaA rare type of cancer that is made up of myeloblasts (a type of immature white blood cell) and forms outside...
- chloroquineA 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and...
- chloroquinoxaline sulfonamideA substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. Also called...
- chlorotoxinA substance being studied in the diagnosis and treatment of glioma (a type of brain cancer) and other types...
- chlorotoxin (EQ)-CD28-CD3zeta-CD19t-expressing CAR T lymphocytesA preparation of genetically modified T lymphocytes transduced with a lentiviral vector expressing a chimeric...
- ChlorozotocinA glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA...
- chlorphenesin carbamateThe carbamate ester form of chlorphenesin, a preservative agent and centrally-acting muscle relaxant with...
- chlorpromazineA phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its...
- chlorpropamideA long-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to other sulfonylureas...
- chlorzoxazoneA benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its...
- chocolate-based dietary supplementA dietary supplement containing chocolate derived from the cacao bean, with potential vasodilating...
- cholangiocarcinomaA rare cancer that forms in the bile ducts. A bile duct is a tube that carries bile (fluid made by the liver)...
- cholangiosarcomaA tumor of the connective tissues of the bile ducts.
- cholecalciferolA nutrient that the body needs in small amounts to function and stay healthy. Cholecalciferol helps the body...
- cholecalciferol/d-alpha tocopherol/L-selenomethionine/green tea extract/saw palmetto berry extract/daidzein/genistein/lycopene prostate health supplementA dietary supplement consisting of a blend of 8 natural ingredients with potential antineoplastic and...
- cholecalciferol/whey protein isolate/EPA/DHA-based nutritional supplementA gluten-free, energy-rich, non-complete nutritional supplement drink composed of juice from the concentrates...
- cholelithSolid material that forms in the gallbladder or common bile duct. Choleliths are made of cholesterol or other...
- cholestasisAny condition in which the release of bile from the liver is blocked. The blockage can occur in the liver...
- cholesterolA waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body...
- cholestyramineAn anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile...
- cholic acid-24-13CA preparation of carbon C 13-labeled cholic acid with potential diagnostic applications. Upon intravenous...
- cholic-2,2,4,4-D4 acidA deuterated form of cholic acid with potential diagnostic applications. Upon intravenous administration...
- cholineA nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy...
- choline kinase alpha inhibitor TCD-717A small-molecule inhibitor of choline kinase alpha (CHKA), with potential antineoplastic activity. TCD-717...
- choline magnesium trisalicylateA substance used to treat arthritis and relieve pain, inflammation, and fever. It is also being studied in...
- choline salicylateThe choline salt of salicylic acid, a nonsteroidal anti-inflammatory drug (NSAID), with analgesic...
- chondrocyteCartilage cell. Chondrocytes make the structural components of cartilage.
- chondroitin sulfateThe major glycosaminoglycan (a type of sugar molecule) in cartilage.
- chondromaA rare, slow-growing tumor that is made up of cartilage and forms on or in bones or soft tissue. It is not...
- chondrosarcomaA type of cancer that forms in bone cartilage. It usually starts in the pelvis (between the hip bones), the...
- CHOPAn abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma and is being...
- CHOP regimenAn abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma and is being...
- CHOPEAn abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma. It includes the...
- CHOPE regimenAn abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma. It includes the...
- chordomaA type of bone cancer that usually starts in the lower spinal column or at the base of the skull.
- chorioadenoma destruensA type of cancer that grows into the muscular wall of the uterus. It is formed after conception...
- chorioallantoic membraneThe membrane in hens' eggs that helps chicken embryos get enough oxygen and calcium for development. The...
- chorioblastomaA malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to...
- choriocarcinomaA malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to...
- chorioepitheliomaA malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to...
- chorionic carcinomaA malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to...
- choroidA thin layer of tissue that is part of the middle layer of the wall of the eye, between the sclera (white...
- choroid plexusA network of blood vessels and cells in the ventricles (fluid-filled spaces) of the brain. The blood vessels...
- choroid plexus tumorA rare tumor that forms in the choroid plexus (a network of blood vessels and cells in the fluid-filled...
- CHP-HER-2 peptide vaccineA peptide vaccine, containing nanoparticles of cholesteryl hydrophobized pullulan (CHP) complexed with the...
- CHP-NY-ESO-1 peptide vaccine IMF-001A peptide cancer vaccine containing nanoparticles of cholesteryl hydrophobized pullulan (CHP) complexed with...
- CHPPA treatment used during surgery in which a heated solution containing anticancer drugs is infused directly...
- chromaffin cellA type of cell that makes neurohormones (chemicals that are made by nerve cells and used to send signals to...
- chromatinA highly organized condensed structure made up of DNA, RNA, and proteins that forms the chromosomes in the...
- chromatographyA laboratory technique used to separate different substances in a mixture. A gas or a liquid is used to pass...
- chromogranin AA protein found inside neuroendocrine cells, which release chromogranin A and certain hormones into the...
- chromomycin A3A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3...
- chromosomal instabilityA genomic imbalance that occurs when a cell has an abnormal number of chromosomes. This can be caused by...
- chromosomePart of a cell that contains genetic information. Except for sperm and eggs, all human cells contain 46...
- chromosome 17One of a pair of chromosomes that is part of the 46 chromosomes found in the nucleus of most human cells...
- chromosome 17p deletionThe loss of all or part of the short arm (also called the p arm) of chromosome 17. The chromosome 17p...
- chromosome 3One of a pair of chromosomes that is part of the 46 chromosomes found in the nucleus of most human cells...
- chromosome 7One of a pair of chromosomes that is part of the 46 chromosomes found in the nucleus of most human cells...
- chronic bacterial prostatitisInflammation of the prostate gland that is caused by a bacterial infection and that continues or gets worse...
- chronic bronchitisA lung condition that develops over time in which the bronchi (large air passages that lead to the lungs)...
- chronic coughA cough that lasts for 8 weeks or longer. It may occur with other symptoms, including a runny or stuffy nose...
- chronic diseaseA disease or condition that usually lasts for 3 months or longer and may get worse over time. Chronic...
- chronic eosinophilic leukemiaA disease in which too many eosinophils (a type of white blood cell) are found in the bone marrow, blood, and...
- chronic fatigue syndromeA condition that lasts for more than 6 months in which a person feels tired most of the time. They may also...
- chronic granulocytic leukemiaAn indolent (slow-growing) cancer in which too many myeloblasts are found in the blood and bone marrow...
- chronic heart failureA condition in which the heart has trouble pumping blood through the body. It may develop over a long period...
- chronic idiopathic myelofibrosisA progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in...
- chronic kidney diseaseA condition in which the kidneys become damaged slowly over time and are not able to remove waste products...
- chronic leukemiaA slowly progressing cancer that starts in blood-forming tissues such as the bone marrow, and causes large...
- chronic lung diseaseA type of disorder that affects the lungs and other parts of the respiratory system. It usually develops...
- chronic lymphocytic leukemiaAn indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly...
- chronic lymphocytic leukemia/small lymphocytic lymphomaAn indolent (slow-growing) cancer in which immature lymphocytes (white blood cells) are found in the blood...
- chronic myelogenous leukemiaAn indolent (slow-growing) cancer in which too many myeloblasts are found in the blood and bone marrow...
- chronic myeloid leukemiaAn indolent (slow-growing) cancer in which too many myeloblasts are found in the blood and bone marrow...
- chronic myelomonocytic leukemiaA slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a...
- chronic myeloproliferative neoplasmA type of disease in which the bone marrow makes too many red blood cells, platelets, or certain white blood...
- chronic neutrophilic leukemiaA disease in which too many neutrophils (a type of white blood cell) are found in the blood. The extra...
- chronic obstructive pulmonary diseaseA type of lung disease marked by permanent damage to tissues in the lungs, making it hard to breathe. Chronic...
- chronic painPain that can range from mild to severe, and persists or progresses over a long period of time.
- chronic phaseRefers to the early stages of chronic myelogenous leukemia or chronic lymphocytic leukemia. The number of...
- chronic phase chronic myelogenous leukemiaA phase of chronic myelogenous leukemia in which fewer than 10% of the cells in the blood and bone marrow are...
- chronic prostatitis/chronic pelvic pain syndromeA condition of the prostate gland that continues or gets worse over a long period of time. Symptoms include...
- Chrysanthemum morifolium/Ganoderma lucidum/Glycyrrhiza glabra/Isatis indigotica/Panax pseudoginseng/Rabdosia rubescens/Scutellaria baicalensis/Serona repens supplementAn herbal mixture with potential antineoplastic effects. PC-SPES, an herbal supplement containing extracts...
- chrysotherapyA procedure that uses gold salts (a salt form of the metal element gold) to treat diseases, such as...
- CHS 828A drug that is being studied in the treatment of solid tumors.
- chyleA milky-white fluid that forms in the small intestine during digestion. It is made of lymph fluid and fats...
- CI-1033A substance being studied in the treatment of some types of cancer. CI-1033 blocks the action of proteins...
- CI-958A substance being studied in the treatment of some types of cancer. CI-958 binds to DNA and stops cells...
- CI-980An anticancer drug that belongs to the family of drugs called mitotic inhibitors. Also called mivobulin...
- CI-994A substance being studied in the treatment of non-small cell lung cancer. Also called N-acetyldinaline.
- CialisA drug used to treat erectile dysfunction. It is also being studied in the treatment of sexual problems in...
- cibisatamabAn anti-carcinoembryonic antigen (CEA)/anti-CD3 bispecific monoclonal antibody with potential antineoplastic...
- ciclopirox olamine lotionA lotion preparation of the olamine salt of ciclopirox, a synthetic hydroxypyridone derivative with...
- ciclopirox olamine oralAn aqueous suspension of the olamine salt form of ciclopirox, a synthetic, broad-spectrum hydroxypyridone...
- Cidan herbal capsuleA capsule-based formulation containing artificial bezoar, Strychni pulveratum (strychnos powder), camphol...
- cidofovirA drug used in the treatment of infections caused by viruses.
- ciforadenantA small molecule immune checkpoint inhibitor of the adenosine A2A receptor (ADORA2A) with potential...
- cifurtilimabA proprietary, non-fucosylated monoclonal antibody directed against the cell surface receptor CD40 with...
- cigarA tube-shaped tobacco product that is made of tightly rolled, cured tobacco leaves in a tobacco leaf wrapper...
- cigaretteA tube-shaped tobacco product that is made of finely cut, cured tobacco leaves wrapped in thin paper. It may...
- cilastatin sodiumThe sodium salt form of cilastatin, a renal dehydropeptidase inhibitor, that can be used to inhibit the...
- cilengitideA substance that is being studied as an anticancer and antiangiogenesis drug. Also called EMD 121974.
- cilgavimab/tixagevimabA combination of two neutralizing human monoclonal antibodies cilgavimab and tixagevimab, that are isolated...
- ciliary bodyA part of the middle layer of the wall of the eye. The ciliary body is found behind the iris and includes the...
- cilostazolA quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III...
- ciltacabtagene autoleucelA treatment used for adults with multiple myeloma that came back or did not get better after treatment with...
- ciltistotugA humanized agonistic antibody targeting the immune checkpoint human B-cell surface antigen CD40, with...
- cimdelirsenAn antisense oligonucleotide targeting the growth hormone receptor (GHR; somatotropin receptor) mRNA, with...
- cimetidineA drug usually used to treat stomach ulcers and heartburn. It is also commonly used in a regimen to prevent...
- CINA term used to describe abnormal cells that are found on the surface of the cervix when a biopsy is done. CIN...
- CIN 1A cervical biopsy finding that means slightly abnormal cells were found on the surface of the cervix. CIN 1...
- CIN 2A cervical biopsy finding that means moderately abnormal cells were found on the surface of the cervix. CIN 2...
- CIN 2/3A cervical biopsy finding that means a mix of moderately abnormal and severely abnormal cells were found on...
- CIN 3A cervical biopsy finding that means severely abnormal cells were found on the surface of the cervix. CIN 3...
- cinacalcet hydrochlorideThe orally bioavailable hydrochloride salt of the calcimimetic cinacalcet. Cinacalcet increases the...
- Cinnamomum cassia capsulesA nutritional supplement composed of the blue-green microalgae spirulina. Spirulina is high in protein and...
- cinobufaginA bufadienolide compound extracted from the dried venom secreted by the parotid glands of toads and one of...
- cinobufotalinA bufadienolide isolated from toad venom and utilized in traditional Chinese medicine (TCM) for its...
- cinrebafusp alfaA bivalent, bispecific fusion protein comprised of an anti-human epidermal growth factor receptor (HER2)...
- cintirorgonAn orally bioavailable agonist of retinoic acid-related orphan receptor gamma (RORg), with potential...
- cintredekin besudotoxA recombinant chimeric protein with potent antitumor activity. Cintredekin besudotox is composed of...
- CinvantiA drug used with other drugs to prevent nausea and vomiting caused by chemotherapy and nausea and vomiting...
- cipepofolA 2,6-disubstituted alkylphenol and structural analog of propofol, that may potentially be used for the...
- CiproA drug that is used to treat infections caused by bacteria and is being studied in the treatment of bladder...
- ciprofloxacinA drug that is used to treat infections caused by bacteria and is being studied in the treatment of bladder...
- circadian rhythmThe natural cycle of physical, mental, and behavior changes that the body goes through in a 24-hour cycle...
- circulating tumor cellA cancer cell that breaks away from the original (primary) tumor and enters the bloodstream. Circulating...
- circulating tumor DNASmall pieces of DNA that are released into a person’s blood by tumor cells as they die. A sample of blood can...
- circulating tumor markerA substance, such as a protein or fragment of DNA, that is released into a person’s blood, urine, other body...
- circulationIn the body, the flow of blood through the heart and blood vessels, and the flow of lymph through the lymph...
- circulatory systemThe system that contains the heart and the blood vessels and moves blood throughout the body. This system...
- circumcisionSurgery to remove part or all of the foreskin (loose skin that covers the head of the penis).
- cirmtuzumabA humanized monoclonal antibody against the extracellular domain of the human receptor tyrosine kinase-like...
- cirrhosisA type of chronic, progressive liver disease in which healthy liver tissue is replaced by scar tissue. The...
- CISThe National Cancer Institute’s Cancer Information Service (CIS) provides cancer-related information to the...
- cisaprideA substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the...
- cisatracurium besylateThe besylate salt form of cisatracurium, a non-depolarizing skeletal muscle relaxant of the...
- CISNETA group of researchers supported by the National Cancer Institute (NCI) who use statistical models to help...
- cisplatinA drug used alone or with other drugs to treat certain types of bladder cancer, ovarian cancer, and...
- cisplatin liposomalA synthetic formulation in which the antineoplastic agent cisplatin is encapsulated in lipids. Cisplatin...
- cisplatin micelle formulation HA132A micelle formulation containing the inorganic platinum agent cisplatin, with potential antineoplastic...
- cisplatin nano-engineered intraoperative system PRV211A nano-engineered intraoperative system containing a liquid permeation enhancer (PE) and a patch composed of...
- cisplatin transmucosal patchA transmucosal patch containing cisplatin, an inorganic platinum agent, with potential antineoplastic...
- cisplatin-E therapeutic implantAn injectable gel comprised of a collagen matrix containing the inorganic platinum (Pt) agent cisplatin and...
- Cisplatin/Gemcitabine RegimenA regimen consisting of cisplatin and gemcitabine that can be used in the treatment of biliary tract...
- cisplatin/vinblastine/cell penetration enhancer formulation INT230-6A formulation composed of three agents in a fixed ratio: two chemotherapeutic agents, the platinum compound...
- cis-urocanic acidA derivative of the amino acid histidine, formed in the mammalian skin from trans-urocanic acid upon...
- citalopramA drug used to treat depression. It belongs to the families of drugs called antidepressant agents and...
- citalopram hydrobromideThe orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with...
- citarinostatAn orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral...
- citatuzumab bogatoxA fusion protein immunotoxin consisting of a humanized, single-chain monoclonal antibody Fab fragment...
- CiticolineA nutritional supplement and source of choline and cytidine with potential neuroprotective and nootropic...
- citric acid monohydrateA tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical...
- citric acid/potassium-sodium citrateA drug used in the treatment of metabolic acidosis (a disorder in which the blood is too acidic).
- citrovorum factorA form of folic acid used alone or with other drugs to treat certain types of colorectal cancer and anemia...
- citrullineA non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of...
- cixutumumabA substance being studied in the treatment of some types of cancer. It is a monoclonal antibody that is made...
- CK1 alpha degrader CC-91633An orally bioavailable degrader of casein kinase 1 alpha (CK1alpha; CK1a), with potential antineoplastic...
- CK1 alpha degrader GLB-001An orally bioavailable molecular glue degrader of casein kinase 1 alpha (CK1alpha; CK1a), with potential...
- CK1alpha/CDK7/CDK9 inhibitor BTX-A51The ditosylated salt of A51, an orally bioavailable inhibitor of casein kinase 1alpha (CK1alpha) and...
- CK2-targeting synthetic peptide CIGB-300A synthetic peptide targeting the substrates of casein kinase 2 (CK2), with potential antineoplastic...
- CKDA condition in which the kidneys become damaged slowly over time and are not able to remove waste products...
- c-kitA protein found on the surface of many different types of cells. It binds to a substance called stem cell...
- CL 246738An immunomodulator, 3,6-bis(2-piperidinoethoxy) acridine trihydrochloride, used in a phase I study for...
- cladribineA drug used to treat hairy cell leukemia. It is also being studied in the treatment of other types of cancer...
- clarithromycinAn antibiotic drug used in the treatment of infections. It belongs to the family of drugs called macrolides.
- Clark level I skin cancerSkin cancer that is found only in the epidermis (outer layer of skin).
- Clark level II skin cancerSkin cancer that has spread from the epidermis (outer layer of skin) down into the papillary dermis (the thin...
- Clark level III skin cancerSkin cancer that has spread down through the papillary dermis (the thin top layer of the dermis) but not into...
- Clark level IV skin cancerSkin cancer that has spread down into the reticular dermis (the thick bottom layer of the dermis).
- Clark level V skin cancerSkin cancer that has spread down into the subcutaneous tissue (tissue beneath the skin).
- Clark levelsA system for describing how deep skin cancer has spread into the skin. Levels I-V describe the layers of skin...
- Class 1 PI3K family inhibitor XL147An orally bioavailable small molecule, targeting the class I phosphatidylinositol 3 kinase (PI3K) family of...
- classic familial adenomatous polyposisAn inherited disorder in which many polyps (usually hundreds to thousands) form on the inner walls of the...
- classic familial polyposisAn inherited disorder in which many polyps (usually hundreds to thousands) form on the inner walls of the...
- classic FAPAn inherited disorder in which many polyps (usually hundreds to thousands) form on the inner walls of the...
- classic Hodgkin lymphomaThe most common type of Hodgkin lymphoma (a cancer of the immune system). Classic Hodgkin lymphoma is marked...
- Claus modelA computer program that uses statistics to predict a person’s risk for developing breast cancer based on...
- clavicleOne of a pair of bones at the base of the front of the neck. The clavicles connect the breastbone to the...
- clavulanic acidA semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam...
- clazakizumabA humanized monoclonal antibody directed against the pro-inflammatory cytokine interleukin-6 (Il-6) with...
- CLDA type of disorder that affects the lungs and other parts of the respiratory system. It usually develops...
- clear cellA type of cell that looks clear inside when viewed under a microscope.
- clear cell adenocarcinomaA rare type of cancer in which the cells look clear when viewed under a microscope. Clear cell adenocarcinoma...
- clear cell carcinomaA rare type of cancer in which the cells look clear when viewed under a microscope. Clear cell carcinoma...
- clear cell renal cell cancerA type of kidney cancer in which the cells look clear or very pale when viewed under a microscope. Clear cell...
- clear cell renal cell carcinomaA type of kidney cancer in which the cells look clear or very pale when viewed under a microscope. Clear cell...
- clear cell sarcoma of soft tissueA soft tissue tumor that begins in a tendon (tough, cord-like tissue that connects muscle to bone or to...
- clear cell sarcoma of the kidneyA rare type of kidney cancer, in which the inside of the cells look clear when viewed under a microscope...
- clear liquid dietA diet that is made up of only liquids and foods that are clear liquids at room temperature. Clear liquids...
- cleavedHaving to do with the appearance of cells when viewed under a microscope. The nucleus of cleaved cells...
- CLEC12A-targeting CCR/anti-ADGRE2 CAR T cells ADCLEC.syn1A preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor...
- clemizole hydrochlorideThe hydrochloride salt form of clemizole, an orally bioavailable histamine H1 antagonist, with potential...
- clergyOrdained individuals who perform spiritual and/or religious functions.
- clevudineA synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is...
- CLIAChanges to a 1988 U.S. law that sets the standards for all laboratory testing that is done on human tissue...
- clifutinib besylateThe besylate salt form of clifutinib, an orally bioavailable, selective, small molecule inhibitor of FMS-like...
- clindamycin phosphateThe phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad spectrum antibiotic produced by...
- clindamycin/hydrocortisone lotionA topical lotion, containing clindamycin and hydrocortisone, with antibacterial and anti-inflammatory...
- clinicalHaving to do with the examination and treatment of patients.
- clinical breast examA physical exam of the breast performed by a health care provider to check for lumps or other changes. Also...
- clinical diagnosisThe process of identifying a disease, condition, or injury based on the signs and symptoms a patient is...
- Clinical Laboratory Improvement AmendmentsChanges to a 1988 U.S. law that sets the standards for all laboratory testing that is done on human tissue...
- clinical practice guidelinesGuidelines developed to help health care professionals and patients make decisions about screening...
- clinical researchResearch in which people, or data or samples of tissue from people, are studied to understand health and...
- clinical research costsThe costs related to taking part in a treatment clinical trial. These costs may include the drug or other...
- clinical researcherA health professional who works directly with patients, or uses data from patients, to do research on health...
- clinical resistanceThe failure of a cancer to shrink after treatment.
- clinical seriesA case series in which the patients receive treatment in a clinic or other medical facility.
- clinical stageThe stage of cancer (amount or spread of cancer in the body) that is based on tests that are done before...
- clinical stagingA method used to find out the stage of cancer (amount or spread of cancer in the body) using tests that are...
- clinical studyA type of research study that tests how well new medical approaches work in people. These studies test new...
- clinical trialA type of research study that tests how well new medical approaches work in people. These studies test new...
- clinical trial phaseA part of the clinical research process that answers specific questions about whether treatments or other...
- clinical trial sponsorA person, company, institution, group, or organization that oversees or pays for a clinical trial and...
- clinical utilityA term that refers to the likelihood that a test will, by prompting an intervention, result in an improved...
- clinical validityA term that refers to the predictive value of a test for a given clinical outcome (e.g., the likelihood that...
- clinicianA health professional who takes care of patients.
- Clino-San vaginal lubricantA vaginal lubricant formulated as a topical gel used to prevent and treat vaginal dryness. With a pH similar...
- ClioquinolAn orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal...
- clivusA bone at the base of the skull, near the spine. Tumors, such as chordomas and chondrosarcomas, may form on...
- CLK inhibitor BH-30236An orally bioavailable macrocyclic ATP-competitive inhibitor of CDC2-like kinase (CLK) family kinases...
- CLK inhibitor CTX-712An orally bioavailable inhibitor of CLK family kinases, with potential antineoplastic activity. Upon oral...
- CLLAn indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly...
- CLL/SLLAn indolent (slow-growing) cancer in which immature lymphocytes (white blood cells) are found in the blood...
- clobetasolA topical synthetic corticosteroid with anti-inflammatory, anti-pruritic, and vasoconstrictive properties...
- clobetasol propionateThe propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory...
- clodronateA drug used in the treatment of hypercalcemia (abnormally high levels of calcium in the blood) and cancer...
- clodronate disodiumThe disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate...
1,658 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.