ChAdOx1-PSA/PAP/STEAP1/5T4 prostate cancer vaccine ChAdOx1-PCAQ

{
  "id": "MLC-T-ONC-012541",
  "term": "ChAdOx1-PSA/PAP/STEAP1/5T4 prostate cancer vaccine ChAdOx1-PCAQ",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of recombinant non-replicating chimpanzee adenovirus Oxford 1 (ChAdOx1) viral vector encoding genes for the prostate cancer-associated antigens prostate-specific antigen (PSA), prostatic acid phosphatase (PAP), six-transmembrane epithelial antigen of the prostate 1 (STEAP1), and 5T4 oncofetal antigen, with potential immunostimulatory and antineoplastic activities. Upon administration, ChAdOx1-PSA/PAP/STEAP1/5T4 prostate cancer vaccine ChAdOx1-PCAQ expresses PSA, PAP, STEAP1 and 5T4 peptides, which may elicit humoral and cellular immune responses against prostate cancer cells expressing these antigens.",
  "synonyms": [
    "ChAdOx1-PCAQ",
    "recombinant ChAdOx1 PSA/PAP/STEAP1/5T4 vaccine ChAdOx1-PCAQ"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/chadox1-psa-pap-steap1-5t4-prostate-cancer-vaccine-chadox1-pcaq/"
}