Clodronate disodium

{
  "id": "MLC-T-ONC-012644",
  "term": "Clodronate disodium",
  "field": "Oncology and biomedicine",
  "definition": "The disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain.",
  "synonyms": [
    "clodronic acid disodium salt",
    "clodronate",
    "dichloromethylene diphosphonate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/clodronate-disodium/"
}