chromomycin A3

{
  "id": "MLC-T-ONC-012586",
  "term": "chromomycin A3",
  "field": "Oncology and biomedicine",
  "definition": "A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3 reversibly binds to guanine-cytosine (G-C) base pairs in the minor groove of DNA, thereby inhibiting RNA synthesis. This agent is used as a fluorescent chromosome dye.",
  "synonyms": [
    "antibiotic 69895 A",
    "antibiotic B 599",
    "antibiotic from Streptomyces griseus",
    "toyomycin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/chromomycin-a3/"
}